PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Acid Reflux pain in arms, pain in side, high anxiety M 31 6 days
1/7/2008
 1  gerd Followup to earlier posts. Even after I went off of omeprazole, I continued to have digestive problems for months -- burping, gas, feeling of regurgitation and lump in throat after meals. This is a followup to my posts on 12/14/08 and 1/3/09. My digestive system is finally returning to normal. I believe that omeprazole, like all proton inhibitor drugs, stopped acid production and killed off the beneficial digestive enzymes. This in turn created a yeast problem. To counteract the yeast, I tried to eliminate all wheat products and processed sugars from my diet. Ate lots of potato dishes, fresh fruit and vegetables, fresh protein. Ate plain yogurt every morning to replace the enzymes. Unflavored Activia is really good. It took a really long time, but I am much, much better. I am now reintroducing yeast products back into my diet. Also dealt with the underlying problem that caused the stress and gerd. TO ALL WHO DON'T THINK THINGS WILL IMPROVE: DON'T GIVE UP! LISTEN TO WHAT YOUR BODY IS TELLING YOU ABOUT YOUR FOOD CHOICES AND FOLLOW UP ON YOUR INSTINCTS. M 47 6 days
4/19/2009
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 1  Gastritis, Acid Reflux Muscle pains, severe joint pain, heart palpatations, blurred vision, & very tired. At first I thought this was a wonder drug until all the side effects started. After reading everyone's comments I realized I have the same side effects. I've researched serveral natural remedies and I've found a couple at my local health food store. F 42 6 days
7/15/2009
 1  helico pyr bacteria Disoriented, anxiety, palpitations Almost passed out, light headed, feeling anxious, heart rate spikes, BP spikes, I'm off the drug now for 3 days, a little better but still not myself. Going through a whole series of EKG and blood tests at the moment M 58 6 days
20 2X day
1/21/2016
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 1  Heartburn achy legs like I have never ever had before! F 59 6 days
1X day
8/10/2022
 1  H Pylori / Gastritis Chest tightness, tender feeling in esophagus when swallowing, very sore neck and upper back, stabbing pain in upper back, rib cage or similar pain, tingling down left leg shin and foot, joint pain in wrists and ankles. Had stomach pains, doctor prescribed omeprazole without doing any tests. Took 1st dose and straight away felt weird sensation in chest, then neck stiffness and pain, back pain and joint pain. Depression. Didn't feel was right, eventually got 2nd opinion. Had endoscopy and tested positive for H Pylori. Antibiotics + PPI Omeprazole 7 days. On day 2 of course noticed very sore right side neck, first i thought this was due to indigestion and reaction to antibiotic (even though first time I ever took antibiotics no reaction like this), but then realised it could be omeprazole as had same pain first time I took it a few weeks back. Then, day 3 got progressively worse. Mid upper back pain, and joint ankle pain left side, depression and feeling so low and moody, creaky voice, sore and dry throat. Over the course of the next 3 days, I was almost bed bound with my laptop as just had no will to do anything (I work from home) and so much pain in my chest and back I thought I was going crazy. Day 6 was the final straw. Took my dose at 5pm. By 5.30, had severe esophageal tenderness that even drinking water hurt! That night in bed I was jolted awake with tingling in my left foot and stabbing pain right side of chest. I have 1 more day of antibiotic course tomorrow, but I'm going to talk to my GP and say I'm not taking another dose of PPI. F 39 6 days
20mg 2X day
7/6/2023
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 1  Acid reflux Panic attacks, general anxiety, fear of dying, heart palpitations, tight esophagus, abdominal pain, mental fog, gas, buzzy feeling in abdomen and legs, muscle spasms, insomnia, psycho dreams, sharp pains under rib cage, feeling strong pulse in abdomen I had chest pains and was alarmed so I went to the ER. Was told it was just bad reflux. Followed up with a doctor and he recommend prilosec otc. 24 hrs after the first dose I had the first of many panic attacks. I sincerely though I was going to die for about a week. I was afraid to be alone with my kids because I didn't want them to see me die. On the 6th day, i could barely swallow and my throat was so tight. My logical brain finally realized something was going on and I started researching. The side effects are insidious. Finding others who shared this awful reaction helped me immensely. This drug is poison to many of us. I experienced all the symptoms I listed for a solid 4 weeks before it started to fade and I only took it for SIX days! I am now 6 weeks off this poison and still have occasional symptoms but thankfully they are weakening over time. M 48 6 days
20 mg 1X day
2/26/2021
 1  Suspected getd Anxiety, chest pain, stomach cramps, random cramps around body. Sleeplessness, irritability, random crying spurts. Moments where I feel fine then BAM heavy chest. Please dont take this if you have history with anxiety. Even if you dont. Itll mess you up. F 23 6 days
20 MG 1X day
9/29/2020
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 1  Acid reflux Tremors, SEVERE anxiety, sore throat, dizziness, fatigue, numb hands and face, bad stomach cramps, back aches. M 27 6 days
20mg 1X day
10/29/2020
 1  GERD Extreme leg, Ankle pain. Started on day four in the middle of the night. Took one more dose and decided to stop. I'll never take this drug again. It's been 36 hours since I stopped still have the leg pains hoping this resolves quickly F 66 6 days
20mg 1X day
10/23/2020
 1  GERD Extreme aching both legs, ankle pain, hamstring tightening My symptoms started on day 4 in the middle of the night. Took one more dose and decided no more! It's now 36 hrs since my last dose . Legs feel miserable still. I hope it resolved quickly. I'll never take it again. Scary stuff. F 66 6 days
20mg 1X day
10/23/2020
 1  GERD Extreme aching both legs, ankle pain, hamstring tightening My symptoms started on day 4 in the middle of the night. Took one more dose and decided no more! It's now 36 hrs since my last dose . Legs feel miserable still. I hope it resolved quickly. I'll never take it again. Scary stuff. F 66 6 days
20mg 1X day
10/23/2020
 1  Acid Reflux/Gastritis Constant heart palpitations...which ended up turning into panick attacks...brain fog... muscle pain in legs....made my original symptoms worst...stop immediately after i read these other post Will never take again!! F 40 6 days
40mg 2x a
1/18/2017
 1  Gastritis Anxiety, racing thoughts, insomnia, loss of appetite, lethargic, depressed, blured vision. This drug should be recalled immediately, after reading what patients have gone through the manufacturers should be held responsible for their inaction to this problem. It’s a disgrace what the pharmaceutical company get away with. Eventually after 6 days of hell I stopped this drug and drank colloidal silver, I will take my chances,I felt better as soon as drinking it in 24 hours. F 50 6 days
20mg
3/22/2016
Email
 5  GERD, Hiatal hernia Slight occasional headaches; seems to have increased appetite (but is that because I'm not worried about heartburn anymore?). Wow! This is an absolute wonder drug (Prilosec OTC 20mg). Had gotten to the point where I had constant heartburn which was making my life a living hell. I was popping Tums Ex-Strength throughout the day and all night, and sleeping upright. Also was having problems with swallowing because of esophigal scarring (Barrett's Syndrom) from too much acid reflux. Please note that I am not overweight, watch what I eat and work out every day. My doctor suggested Prilosec OTC 20mg and within 5-6 hours my pain completely vanished (unbelievable!). I have also noted that I haven't had any problems with swallowing since I've been on this medication. Only negative side effect has been occasional slight headaches (took a couple of Advil). I'm hoping I will eventually be able to reduce the Prilosec dosage to every other day once my scarring has healed. F 51 7 days
9/27/2005
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 5  Gerd Very minimal if any. I got more side effects from Rolaid's. I tried all of the antacid's available at the time and still had indigestion and GERD problems. Prilosec (Omeprazole) solved all of the indigestion and Gerd problems immediately. I didn't like the high prices at the pharmacy so living in San Diego I drove to Mexico and found it for $79 for 180 20gr capsules. M 63 7 days
11/27/2005
 4  heartburn very bad gas, insomnia, out of it feeling during the day Thank God for this web site. I recently had radiation to my brain and am on chemotherapy. I've been blaming my symptons on that. Now that I've read every one else's side effects I realize mine are also from the prilosec. I will stop this drug immediately. F 49 7 days
2/21/2008
 4  Heartburn None yet. I decided to try this after getting rid of Nexium. I also tried Pepcid, but that didn't work much at all. If I'm not on any medications, I will have heartburn for most of the day, every day. Prilosec is definitely working, but I still burp up acid every now and then. F 19 7 days
6/23/2009
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 3  ER dr recommended in lieu of Zantac upset stomach, cramps, diarrhea, constipation, achy lymph nodes, brief daily stabbing headaches It works, but... I cannot confirm that Prilosec is the cause of any or all of these symptoms; however, it is suspicious that they were concurrent with my first week's use of the drug; all but the headache and constipation have persisted now several days after ceasing dosage M 49 7 days
1/4/2007
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 3  Gastritus, vomited blood I took it in the evening to see how I would react. I woke up with a really puffy face! It went away but I felt so lethargic the first half of the day. Hasnt happened since, but now I have itching (but no bumps) on my body: mostly the abdominal area. Will call Dr. to see if it's somthing to take seriously. F 25 7 days
10/17/2006

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