PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Reflux asthma severe depression, severe anxiety, panic, agitation, confusion, rapid thoughts, social nervousness, fatigue, feeling very cold, lump in throat, mild sore throat, increased stomach pain My asthma doctor prescribed this to see if it'd lessen my need for my rescue inhaler from attacks I get after eating and I wish I wouldn't have touched this stuff. I already have depression and social anxiety and adhd-type symptoms, but have been relatively stable lately and all that changed 2 days into taking this. Wasn't sure at first if it was the medication until I started googling reviews. I've been feeling like I'm losing my mind. I haven't noticed a significant improvement in my ‘reflux' since I never have heartburn, though I haven't reached for inhaler daily like I was before. It's definitely not worth it and I'll just stick with my inhaler. Glad I got on here and read through some of these reviews so now I know it's not just me. It's crazy that a medication like Prilosec can cause so much emotional trouble for someone in four-days' time. F 29 4 days
20 1X day
11/13/2020
 1  Eosinophilic esophagitis I suffered extreme lethargy as well as severe diarrhea and projectile vomiting. I went to ER because I was so desperately ill. All tests came back normal. I will never take this drug again. F 60 4 days
10
9/9/2020
Email
 1  GERD excessive belchin sleeplessness, elevated heart rate, elevated blood pressure, abdominal cramps, jitters, wierd dreams F 55 4.5 days
2/8/2008
 5  acid reflux None. Wouldn't take anything else. M 48 5 days
20mg 2X day
3/6/2010
 4  acid reflux A lump in my throat- I thought it was some kind of tumor because I am a professional singer. The omeperazole/prilosec DID help amazingly! I drink wine and that seemed to cause the acid reflux just suddenly about 6 months ago. I would take a pill 20 minutes BEFORe wine and VOILA! all was fine from the miserable previous effects of acid reflux- burning esophagus, nausea feeling and stomach cramps. If the doctor just TOLD ME- the trade off is-- acid reflux gone BUT you will experience a lump or tumor feeling in your throat- then I WOULD KNOW and not experience great anxiety thinking my throat may be swelling and I would sufficate and die if I do NOT go to ER or that I may have polyps due to singing , etc! It is the NOT knowing that causes great problems- PLEASE advise patient specifically and correctly- LUMP in throat, dry skin and dehydration IF you take this pill and if you don't then suffer acid reflux or delete specific items from your diet- simple and exact and no trip to ER! Oh and The drug DID remove my acid reflux immediately upon taking just one 20 mg pill; but the lump in throat would appear maybe 6 to 24 hours later and dry skin in hands/appendages was quite severe since I already have dry skin. Dehydration also occurred and diarrreaha (sp?) but did not know all 4 were related until I came to this website. Thanks! F 42 5 days
20 mg 1X AN
8/25/2010
Patient History
 4  ulcer Flu-like symptoms. Ulcer pain stopped within hours. Then same night developed severe head cold, severe coughing incidents. Coughing woke me every 1-1.5 hrs. Extremely fatigued after days/nights of taking only short naps, then waking with severe coughing episodes. Coincidence? or Side effects of P? Not going to take the P this afternoon. I gotta get some decent sleep. Let me know if anyone else has had this experience. Send me email. My numerical rating of "4" is because it did stop the ulcer pain, or maybe the Chimichanga I ate at the same time stopped it. No kidding! M 64 5 days
5/6/2007
 4  GERD Some uneasiness and stomach irritability I’ve had GERD for the last couple of years. Two months ago I started having “lump in throat” feeling and last month my doctor prescribed Prilosec. After reading comments here, I decided not to take it… what a mistake! I’ve been dying every day from “choking from lump in throat”, until it became unbearable. Finally, I decided to take Prilosec. After only two doses, lump in throat disappeared. I feel so stupid for suffering for so long, even though I had this medication all the time, but didn’t take it because I was afraid of horrible side effects people described here. F 44 5 days
20 mg 2X day
3/20/2014
 3  GERD Episodes of anxiety, head & face pressure. Headaches & dizziness. Dry mouth, throat. Lump feeling in throat. A little bit of confusion. Ringing in ears, head. Muscle spasms. Chest, stomach & abdominal pain. Nausea. Trouble breathing at times. Frequent urination, constipation & diaherra. Trouble sleeping. Rapid, fast & abdnormal heartbeats (especially at night) I rate it a 3 because it has helped with my GERD symptoms a lot. No more burning in stomach or chest. But these side effects are horrible! I had an EKG & CT scans & blood drawn all in less than a week. They checked my heart, lungs, stomach, liver, kidneys, pancreas. Everything was fine. So it has to be this medication. Can't wait till I finish my 2 week treatment. M 20 5 days
20 MG
2/28/2015
Email
 3  Acid Reflux I am very happy with the results of how it has helped my acid reflux but...I have been on it for 5 days now and am having vertigo. So far it seems to happen only when I move to quickly(which isnt often due to severe back problems). I think I will give it a lil more time to see if it worsens. I am willing to put up with the dizziness for now at least at this degree. It seems manageable if I rise slowly and dont move fast. F 45 5 days
11/4/2009
 3  Acid Reflux causing throat pain Facial skin rash on cheeks, next to the nose. Lower left back pain that didn't allow me to sleep on one side. Dry mouth and metallic taste in my mouth. Was not on any other medication (other than a Tdap vaccine) during these 5 days. It did help my acid reflux though, so I stopped after the first 5 days. Hoping that the skin rash will go away soon (has been 3 days since I stopped Prilosec) M 36 5 days
20mg 1X day
4/15/2018
 3  gastritis lightheadedness on day #1, also starting getting muscle pains in the back on the right side and down right arm, also feelings of sadness am so glad to find this site, i thought i was becoming a hypochondriac with the side effects happening so soon after I started the Prilosec (which is helping the gastritis). but would like to find another drug with less side effects!! F 35 5 days
10/8/2007
 3  acid reflux headache, depression, bloating, stomach pain, feeling spaced-out--just like I had a big dose of MSG--in a major fog all day. stopped the acid at night, but jeez, my daytime life is not fun being so depressed and out of it. M 44 5 days
3/24/2008
 3  gastritis HORRIBLE painful leg cramps. Generalized muscle, joint and bone pain. Prior had NEVER had this pain in my life. Going to quit and try zantac instead. I developed these symptoms by day 4 which is really fast. It did take the stomach pain away but replaced it with serious joint pain. F 49 5 days
20 mg 1X day
3/14/2010
 3  acid reflux/ dyspepsia M 68 5 days
20 mg 1X day
8/24/2010
Email

Patient History
 3  Acid reflux/gastritis dry mouth, burning lips, headache, insomina(I would only sleep a few hours a night), mood swings, anxiety (to the point that I just said forget it - when you start thinking about throwing a stapler at someone, about people coming to hurt you, having a wreck, etc. and you didn't do it before the medicine, and it started the day you took the medicine, well...) fogginess, flu like symptoms I was having major reflux - that included palpitations, etc, gurgling and pains and burning in the stomach. They told me I had a UTI and a sinsus infection - gave me Zpack first (horrible reaction to that), then they gave me Cipro (GROSS) and I got off that and started the prilosec. IT could be that the 20 mg was too strong a dose for me - and it seems to have knocked out the gas and palps, but the anxiety just got to me. I go back to my doc on Thursday. I just am medicine phobic because every time I take something - I get weird reactions. Hoping these side effects go away SOON! Funny thing is - I had the burning lips when I took Zegerid too. I do have thyroid problems and I take synthyroid and perhaps this has been inhibiting my medicine - we just adjusted that a little - and hence more anxiety, i am sure. Just not going to take this unless I am seriously ill. Would like to know from other people about the anxiety - if it really made them more anxious or if it just what people say here? F 41 5 days
20 mg 1X day
11/14/2011
 3  Acid Reflux & Stomach Pain Broke out in hives on lower half of body. NEVER had any signs of hives in my life. It works. Helped on the stomach and acid reflux even after 5 doses. Will have to find something else though since the hives are scary. M 37 5 days
30 MG 1X day
8/5/2011
Email
 2  Acid/Heartburn Weakness - Severe Constipation - Bloating/Gas After being on this for 5 days, I deduced that it was giving me severe constipation. Also, because of the bloating and gas, sleeping was uncomfortable (I don't think it caused sleeplessness directly). I've stopped taking it for 2 days now, but the side effects are still there. I'm going to wait a few more days and see if it subsides. I did seem to help with the acid/heartburn, but mine isn't severe, so this wasn't worth it. M 39 5 days
20 MG 2X day
12/26/2011
Email
 2  GERD Hand and feet swelling; fatigue; lightheaded; muscle aches in shoulders, arms and legs. M 64 5 days
20MG 1X day
5/24/2012
 2  acid reflux I was taking omeprazole for the last 3 months, terrible pain in stomach and anxiety which became much worse, bouts of diarrhea then constipation so went off that and now taking the over counter prilosec 20 mg which started off ok but now pains are coming back. F 52 5 days
20 mg 1X day
11/24/2010
Email
 2  Ulcer EXTREME thirst, nasty phlegm globs in back of throat, calf pain, anxiety. It took my acid reflux away, but the thirst I felt was crazy. No matter how much water I drank I was thirsty. I stopped after 5 days and the day after I stopped the thirst went away. M 33 5 days
20mg 1X day
12/9/2010

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