PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  GERD, persistant sore throat panic attacks, heart palpitations, dry eyes and blurry vision, numbness in my hands and feet, hair falling out, headache I thought I was going to have to go to the ER as I have NEVER experienced anything so scary. My stomach felt like I was hungry, my head hurt, my mouth was dry and my eyes were dry with blurry vision and I was in a complete state of panic. Will never take this medication again. Threw it in the garbage. I too called the dr. and pharmacist who said they didn't think these symptoms were from the medication. F 40 4 days
7/2/2009
 1  sour stomach I have mild anxity but wow its beed awful the last few days, and my heart is racing. after reading reviews I know why. Also felt way more sick to my stomach than b4, burping way more and awful stomach cramps (both stomach and having to use the bathroom).. dry mouth that can't be satisfied, feeling oflump in my throat and dry cough.... I'm gonna stop taking it today scared of how worse it could get F 25 4 days
20mg
6/20/2012
Email
 1  acid reflix Made me me odd not myself. Anxiety that got worst, had mood swings off and on again. And thouhts of harming my self Don't not take this med it changea that why you think. M 20 4 days
20 mg
6/25/2012
Email
 1  Reflux I cannot believe what I am reading. I have had all the side effects. Will never take again. I had diarrhea, anxiety, feeling like I can't breathe. Very weak like I have low blood sugar Will go back to the apple cider vinegar and watch what I eat F 51 4 days
20mg 1X day
8/12/2013
Email
 1  Ulcer Numbness in legs, headaches, stomach aches, red numb face with a tingling feeling some times also with decreased sensitivity in it, head feeling out of it, dazed. I went to the ER in Jan 2010, feeling like I was out of my body. With head pains in everything. At that point I had stopped the Zantac as that was what I was taking at the time. I did not know it was the medicine. At the end of Jan, my stomach pain had returned so I started taking the Zantac (ranitdine) again, after a couple days I felt weird and read that Priolsec (the offbrand) was better at healing ulcers in the studies they had done. Well, I happened to have some on me from last year (it has not experienced yet) and when I took it I had only taken it a couple times. So, I took it every morning at 9 or 10am. Before I ate. The 1st day an hour after I took it I felt out of my body and crazy. By the 4th day my face was hot and numb for a couple of hrs then it would go back to normal. I've stopped taking it for 3 days now, I need to know how long it takes to get out of someones system and if anyone else has experienced these things. I still have some numbness in my legs and in my face it's red and numb. Please EMAIL me and tell me if you guys experienced this and how long it took to go away! I am taking benedryl right now, because the dr thought maybe it was an allergic reaction to it. The benedryl works a little, but I still have the numbness. So, IDK. Please Email and help! Thanks in advance! F 30 4 days
1 20 MG 1X day
2/3/2010
Email
 1  STOMACH ACID ISSUES ANXIETY ANXIETY ANXIETY! HORRIBLE FEELING! HAVENT HAD THOSE IN YEARS BUT THIS MEDICINE DEF... DOES IT! HAD TO STOP AFTER 3 DAYS! SYPTOMS WENT AWAY AND NOW I FEEL NORMAL AGAIN! HAD THE SAME THING HAPPEN WHEN TAKING AN ANTIBIOTIC CALLED OMNICEF?? WONDER IF THEY HAVE A SAME ACTIVE INGREDIENT ??? F 42 4 days
1/27/2010
 1  Recurring heartburn, acid reflux Stomachache, abdominal bloating, constipation, loss of appetite, elevated blood pressure, anxiety, insomnia. On the first couple of days I took prilosec the heartburn eased up and there were no problems. Day 3 is when things started going downhill. I started feeling abdominal pains and my stomach would become bloated if I even ate as little as a couple of slices of toast, so that pretty much killed my appetite. Then yesterday (Day 4) my blood pressure, which is controlled by medication, started to spike up to 150/95. I also became very jittery and was too wired to sleep last night. I decided last night to stop taking prilosec because the side effects were worse than the heartburn. It was only after doing a google search on side effects that I found this place, I wish I had sooner. At the very least there should be a warning on the box for people with hypertension. This experience has taught me to be much more vigilant in the future about researching side effects before taking new medication. F 45 4 days
20mg 1X day
3/1/2010
Email
 1  GERD Severe nausea, bloating, gas, dizziness, blurred vision, tingling in arms and hands, weakness, tiredness, insomnia, constipation. Heartburn/Acid Reflux went away, but the side effects are worse. 4 days on this was enough for me. I'll stick with TUMS. F 26 4 days
20MG 1X day
3/4/2010
 1  acid reflux headache, drowsiness, stomache, nausea, dry tight throat, hard to swallow I was ready and willing to take this drug advised by my doctor. When I called the office to report the side effects the nurse said, "Oh I have never heard of it doing that to anyone" Hmm, I think the doctors don't believe us, and not sure why that is. She said get off of it, see how you do, come in if you are not better. I am trying Mylanta for now and not sure what to do. F 61 4 days
20mg 1X day
7/28/2010
 1  GERD blood pressure went up to 180/100....extreme anxiety, sick to my stomach, especially when lying on side, dizziness, feeling like I was going to die, felt like I was going to pass out,confusion. I cannot believe this drug is on the market. On day 4 my GERD was better, but I felt like someone should take me to the hospital because I thought I was having a nervous breakdown. This drug should be off the market. How long does it take for these symptoms to go away ???? I've been off it now for a day and a half and I am starting to feel myself. Also I am having blurring vision. I thought I was having a stroke !! I cannot stand the Pharm companies !!! F 57 4 days
20mg 2X day
11/18/2010
 1  Asprin stomach burn super high blood pressure (180/130), hypertension, rapid heartbeat (100 bpm), chest pains, shortness of breath, blurry vision, difficulty swallowing, potassium deficiency This drug has wreaked havoc on my body like none other. I am a 23 year old college student who eats healthy, exercises every other day, doesn't smoke, and doesn't eat salty foods so you can understand how surprised I was for this to happen. The first two days of taking Prilosec were great. My gastritis was gone and my spirits were up. By the third day I began to feel weakness in my knees and pain deep in my arms and legs where my veins were. Then on the fourth night I came very close to having a stroke. I couldn't check my B/P at the time but all the veins in my neck were protruding and my heart felt as if it was gonna explode. I went to the doctor's the next day and my b/p was 180/140! I have been to multiple doctors, emergency rooms, and even my psychiatrist since and they all say it is the same thing: anxiety. This infuriates me. I stopped taking Prilosec OTC 42 hours ago and expected to be back to normal by now but my blood pressure is still through the roof (anywhere between 160/95 - 140/110) and am now worried I have done permanent harm to my cardiovascular system. I am going to my regular doctor on friday to start blood pressure medicine. Any Idea how long these symptoms will last. Please Email M 23 4 days
20mg 1X day
8/24/2010
 1  GERD Severe headache, fatigue and irritability. M 52 4 days
20 MG 1X day
11/28/2010
 1  acid reflux muscle weakness, headaches, foggy head,felt like i had pins and needles in my brain, sharp pains in the ribs/stomach, legs felt like they were dead as did my arms, extreme fatigue. DONT TAKE THIS DRUG!!!! i have just stopped taking this after 4 days, i have 2 young children and i have not been able to function for the last four days!!!! glad ive stopped it now after realising what bad long term effects it can have! im feeling more myself now after 2 days of stopping it, my brain has been freed and the muscle pain has gone... it really is poison!!!! just thought id google if anyone else has been affected by it and i am shocked at this site, not just me then lol F 31 4 days
20mg 1X day
3/17/2011
Email
 1  stomach ulcer Blood pressure went from normal to over 160/100, chest pain, heart palpitations, excessive urination, dizziness, stomach pain Within 4 days of taking Prilosec twice a day as prescribed by my doctor, my blood pressure shot up and I began experiencing chest pain. I suspected it was the Prilosec, did some research on the internet, and found this is a fairly common side effect. I had almost all of the signs of overdose from it. Manufacturer recommends 1x per day for 14 days, and then you can't take it again for 4 mths. Wish I had known that sooner!! I was supposed to be on it 2x daily for a month, but 4 days did me in. I'm also on Carafate for the stomach ulcer, but the Prilosec made my stomach hurt worse than it did previously. There is NO WAY I will take this drug again! Going to find a natural alternative and change my diet instead. F 39 4 days
20 2X day
3/30/2011
 1  Chest pain due to acid reflux 2nd day felt better but after that way worse. Chest pain increased and I can't even find a position to drive in comfort. M 58 4 days
10/1/2009
 1  Target Generic Omeprazole Dry throat, Fatigue, Constipation Took one pill 20 mg for four days though the Doctor told me to take two a day (40 mg daily). I stated noticing the constipation, I have to force myself to have a bowel movement. Been having a dry throat and noticing I was becoming more tired during the day. I am grateful that I did not take the 40 mg a day as I was told. Been off of it now for three days and still having trouble with what I mentioned earlier. M 40 4 days
8/19/2009
 1  Ulcer Increased HR at night and sometimes during the day, BP, night sweats, palpitations (especially in the middle of the night... they would wake me up), anxiety, depression I took this for 4 days and started to experience heart palpitations and night sweats with an increased heart rate. I was having extremely depressing thoughts and broke down daily. I just stopped taking it today and was wondering if these symptoms went away for anyone and how long they took? Email me! Thanks M 21 4 days
40 1X day
3/25/2013
 1  bile, acid reflux I experienced dizziness all day on 1 pill a day along with stomach ache, trembling, nausea and vomiting, cloudiness in head, fatigue... I researched the ingredients and find it shocking that the FDA ALLOWS the consumption of such a combination of poisons by humans! The medical field in general ignores the importance of 1st testing for HPylori and eradicating it as it is a sinister bacteria. They simply mask it w/ dangerous poisons like PRILOSEC instead!! If you have Hpylori have your doctor prescribe OMECLAMOX for PRECISE eradication because even chemotherapy won't kill it, it simply cloaks itself and becomes stronger. 56 4 days
20mg
6/27/2015
 1  gastritis anxiety, dizziness, lethargy, blurred vision, nightmares, insomnia, dry mouth, , depression, dry eyes, dry throat, dry skin, migraines, agitation, vertigo, nausea, horrible brain fog, feeling very dehydrated. I had to stop today after only 4 pills. Each day it got progressively worse (the side effects). I feel much worse after starting this medication. If you google "wistar rats, anxiety, lansoprazole (yes I know this is omeprazole in Prilosec but I think any of these PPI's are similar), then you will come across a study that shows that lansoprazole (Prevacid) induced anxiety in the wistar rats by increasing the Substance P in their brains which is anxiogenic (increases anxiety). So it is not a stretch to think that if lansoprazole could do this rats, probably omeprazole has the same effect on Substance P and anxiety. Increase substance P also causes increased pain. Lovely drug, these PPIs. No more for me. I hope the side effects go away soon. F 4 days
20 1X day
4/27/2015
 1  Acid reflux Extreme anxiety, feeling of doom, tearful most of the time, made my throat worse. My GP thought my sore throat was due to acid reflux. She gave me omeprazole. It worked for 2 days but the sore throat was worse after that and my anxiety went through the roof. Three weeks later I had enough and went to another doctor who gave me nexium. This worked and did not cause anxiety. (At this point I Do not think I had acid reflux in the first place). When that dose finished I was then put on omeprazole again. And OMG my anxiety and paranoia has come back with a vengeance. It makes me feel so low and tearful. So I have left it for the last three days and I seem To be feeling better. Still anxious but but not as bad. Cannot wait to flush it out. To be honest I do not even think I had acid reflux to begin with so I think these have caused more damage. Just going to let me body heal now and recover from suppressing the acidity. F 43 4 days
20
6/27/2020
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