PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Gastroparesis Syndrome Anxiety, Bad dreams, waking up in middle of night, unable to get back to sleep. I have only taken about 7 of these pills and starting having anxiety almost immediately. Last two nights have been especially rough, Thank God for my wife. Doctor just told me to stop taking it. M 50 3 days
3/10/2008
 1  acid reflux anxiety attacks, confusion, diarrhea, memory loss, couldn't remember what my dog's name was. Symptoms began occuring on the third day. SHOULD BE RENAMED PRILOSUCK F 44 3 days
8/1/2007
 1  night-time acid reflux It triggered a leaden depression I haven't felt for years and increased my anxiety attacks and muscle tension. My digestion seemed to quit working altogether - zero appetite, bloating, continual burping... worst was the inability to sleep because I was hiccupping non-stop every time I lay down. I had to sleep on the couch because the bed was shaking so hard my poor husband couldn't sleep. I didn't expect problems from this - the pack makes it sound like a side-effect-free wonder drug. It's not. I only took two pills, felt the effects, and THEN read about them here... DH thought I was depressed because the prilosec didn't solve my sleep problem, but that wasn't it. I felt like I was having a nervous breakdown this week, but now the prilosec's out of my system I feel a thousand times better! It cut down my stomach acid - too well! Do NOT take this med if you have problems with digestion or anxiety/depression. One plus - it did reduce the acid and prevent night-time choking. Only I still couldn't sleep because of its other effects. F 35 3 days
9/29/2006
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 1  Acid Reflux, H. Pylori, Gastritis I felt like a mental health case, experiencing severe anxiety that was leading to depression. Suffering from vision problems, headaches and tight neck and shoulder pain, probably due to the hypertension it seemed to be giving me. It felt like I was hyped up on caffeine. I also had trouble getting to sleep, once asleep I was more inclined to have vivid dreams, as mentioned by others. These side effects were hideous. Prilosec worked incredibly well in eliminating the acid reflux I was experiencing. The trouble I had, swallowing, dissipated and so did the abdominal pain I felt after consuming spicy or fatty foods. However, when advised, by my doctor, to increase the dosage of omeprazole from 20mg to 40mg the anxiety went through the roof. So too did the headaches and blurriness of vision that had grown progressively worse since I began taking the medication. 4 days ago I ceased taking this medication and am already noticing a vast improvement. I take no other medication so I can clearly attribute this improvement to the removal of omeprazole from my life. Although I seem to be experiencing acid reflux again in my throat, this is a small price to pay for the anti depressant drugs my doctor was likely to prescribe for me, to address symptoms brought about by another drug. M 31 3 days
1/2/2007
 1  gerd depression, anxiety, carb cravings,weight gain, ect. I love the drug, but too many side side effects, it is not worth. While on it, I couldn't stop eating, I gained 5 poundes in 2 days. F 21 3 days
7/29/2006
 1  LPR Waking up in the middle of the night with severe heart palpatations, shortness of breath, MAJOR ANXIETY, sense of dread. Prilosec made me suicidal. I thought I was going insane. My heart has been pounding nonstop. I would not have attributed this to Prilosec if I hadn't read this thread.. Stopping the medication immediately. I pray that this feeling goes away. F 25 3 days
20mg 1X day
3/10/2022
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 1  Gastrointestinal issues Hot flashes,cold chills, complete loss of appetite, insomnia I was doing ok until I took this medication, I feel like I have been poisoned M 40 3 days
20mg x1 1X day
2/20/2023
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 1  Acid Reflux First day after taking the medicine, I woke up with flu like symptoms (muscle aches and extreme fatigue). Got worse the second day after taking the second dose. Started feeling better a few days later but the acid reflux came back. Took one pill and by the end of the day I had Muscle weakness, tingling, pins and needles all over my body. If anyone has any advise pls email me. F 25 3 days
20mg 1X day
1/4/2021
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 1  Gerd I only took this medicine for 3 days and started to have severe anxiety. I've always had mild anxiety, but I've never in my life been depressed. Lately I've been feeling super depressed, and have lost all interest in my normal hobbies. I've been off the medicine for for 5 days now and I still get super anxious and don't have any interest. I'm hoping it will get better I'm due time. Wouldn't recommend this at all. M 28 3 days
1X day
9/13/2020
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 1  Gastritis After 3 days of use severe stomach pain, instant diarrhea and severe burning diarrhea. Second attempt at trying this med, same results. Not for me. Terrible experience both times M 67 3 days
9/19/2020
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 1  Gastritis After 3 days of use severe stomach pain, instant diarrhea and severe burning diarrhea. Second attempt are trying this med, same results. Not for me. Terrible experience both times M 67 3 days
9/19/2020
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 1  Heartburn Vertigo!!! It was awful!!! Prilosec depletes your body of vitamin B12 which is needed to digest food & causes vertigo. I'd rather deal with heartburn than feeling like I'm spinning for days & vomiting. F 50 3 days
20mg 1X day
10/16/2020
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 1  Silent Reflux Lightheaded, extreme flatulence, burping.. General feeling of off balance. Constipation. Had some issues due to neck problems prior, this just seems to magnify them, don't think they are the "cause" except for the gas/constipation F 46 3 days
20.6mg 1X day
4/22/2016
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 1  Gerd ,hiatal hernia Soar throat, anxiety,dry mouth Do not recommend. I was on protonix for 6 months which gave me heart palpitations. Switched to pepCid didn't work after while.Dr put me on prilosec 40mgs been on 3 days n I feel terrible.I have been healthy up until this Gerd 2years ago..not taking anymore I'll go on a strict Gerd diet and hopefully won't need any meds ! F 46 3 days
40 mg
4/15/2017
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 1  GERD Increased anxiety, increased heart rate and horrible palpitations. Extreme fatigue and just plain feeling "out of it". Before anyone begins taking Prilosec OTC for GERD....BEWARE... This med has an MAJOR interaction with many antidepressant and anxiety drugs. I take Celexa for anxiety and depression. I did not consult my physician. I took this med to alleviate temporary GERD symptoms but the side effects were much worse after only 3 days of treatment. Stopped cold turkey!! Always check for interactions between prescribed meds before taking over the counter drugs. I learned a valuable lesson. NEVER AGAIN!! M 68 3 days
20MG 1X day
5/21/2017
 1  Possible damaged esophagus from flu Nausea so bad I was up all night running to the bathroom feeling like I had to vomit. Loose stool, heart palpitations, anxiety, muscles spasms followed by muscle soreness in legs and eye irritation. My doctor prescribed it to me after making a guess at why I had chest and stomach pain for 3 weeks. I had had the flu and possibly suffered damage to those areas because of all the coughing. I had been feeling perfectly fine, other than the chest/stomach pain, for the past week until day 3 of taking Prilosec. It almost felt like I had the flu again (although flu is worse). This is the next day and the nausea hasn’t fully gone away. F 37 3 days
40 1X day
3/16/2018
 1  gastritis Severe Muscle pain in back & down my legs. This is the second time I tried prilosec & same issue- can't sleep due to muscle pain in the back & down the legs. I thought I was going crazy, but it has to be the prilosec. M 50 3 days
20mg 1X day
10/4/2017
 1  GERD Nausea, nearly vomiting, headache, fatigue, weak jittery feeling The benefits are not worth continuing this medication with these horrible side effects - calling my doctor today. F 64 3 days
20 MG 1X day
3/23/2018
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 1  Acid reflux Extreme chest tightness and burn, zapping electrical type pain in arms and under ribcage, severe panic attacks, agitation, dizzy and brain fog Why is this stuff being prescribed is what I want to know! I ended up in the ER thinking I was having a heart attack!! F 55 3 days
20 mg
3/5/2019
 1  GERD Arm and leg tingling, burning sensations in feet, muscle weakness, anxiety and panic attacks, rapid heart rate, shortness of breath, muscle twitching, excessive burping I took Prilosec for 3 days and stopped because the third day I experienced pins and needles sensation in my arms and legs immediately after taking the 3rd pill. I had an anxiety attack within an hour of the pill and have spent the past 3.5 weeks in an anxious state. The tingling/pins and needles in my arms went away and lasted in my legs for about a week, however, now I’m left with constant burning sensations in my legs and feet. It is worse when I lay down before going to bed and is still there when I wake up in the morning. My muscles also feel so weak. Things I used to be able to do with no problem make me feel tired. Like walking up the stairs makes my legs feel weak. I can’t believe an over the counter drug can cause such horrible symptoms. Doctors say it’s my anxiety but I never experienced anxiety like this before taking Prilosec. It has ruined my life and been the worst month of doctor appointments and ER visits. I have lost hope of this burning feeling going away. Panic attacks were extreme the first week stopping Prilosec. I would wake up in the middle of the night hyperventilating and crying. 2nd week panic attacks are gone and anxiety calmed down. 3rd week I thought anxiety was gone but I feel anxious when I wake up and after I eat. So weird. Will the anxiety ever go away? If you have experienced tingling and burning sensations in your legs after taking this Prilosec email me. I want this to go away!! F 25 3 days
20 mg
7/26/2019
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