PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Acid reflux Gained 30 lbs since I started taking it while working out 4-5 days a week increasing the intensity due to the weight gain but I just kept gaining. Unquenchable thirst, days when I'd spit thick sputum all day, headaches, dizziness, memory problems, feeling like I just can't think, some days hungry all the time and other times I don't have an appetite for a week, hip pain that woke me from sleep that hurt so bad I was in tears, dry eyes, extreme fatigue doesn't come close to describing the last 3yrs. My body has felt so exhaustively heavy i can barely get off the couch to workout 3 days a week ( I used to be up to 10miles running without feeling tired).Lately I'm tired after being awake for 3hrs, I'm falling asleep by 7pm but I can only sleep for 3hrs a night then I toss and turn, I used to work at least two jobs now I can barely work part time at one job. I've stayed very diligent about eating right and exercising and I've had no reason to believe that just getting older would cause I stopped taking prilosec a week ago and I've been sleeping through the nights, I worked out today and felt 10yrs younger I had so much energy. I feel renewed and no longer out of sorts. F 40 10 years
20mg 1X day
7/9/2012
 3  GERD The Prilosec helped the reflux, but I have stomach cramps, belching; and a feeling of anxiousness and anxiety. Dr. switched me to protonix 2 days ago, still feeling uneasy. Wants me to have an ultrasound on my belly but after reading all this I'm convinced I am dealing with side effects of 40mg of daily Prilosec M 52 4 months
20mg 2XD 1X day
5/11/2012
 3  Acid reflux and Barretts Diareha mostly, slight mental effects. Have to alternate between other forms of PPIs Concerned about long term use. They need to come up with another solution. Dr. Insists that I stay on acid reducers to prevent further scaring and the potential from my Barretts to turn to cancer. If you suffer from GERD or Barretts people make sure you have an upper GI yearly for cancer screening. M 49
20 1X day
2/6/2012
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Patient History
 3  Acid reflux I'm sitting on the fence about this medication at the moment. There is no doubt that my stomach feels MUCH better than it did 9 months ago but there are definitely side effects, some of which I'm only starting to link to the drug. I'm constantly exhausted & have become really forgetful (but do have a stressful job so unsure of linked!). I also sometimes feels really nauseous, even more so than before I started taking the meds. Also, pain underneath left rib cage, numbness in fingers, vertigo (all only occasionally) and started developing facial hair on one side. Also head & neck ache. It's hard to say whether any or all of these symptoms are linked to Prilosec but after reading some of these reviews I'm starting to think I might be better off just suffering from the pain of acid reflux!?! F 31 9 months
1/24/2012
 3  Acid reflux/Esophagitis It seemed to help subside the pain from the reflux/esophagitis, but had a ton of very frightening side effects so my doctor told me to stop taking it. Still trying to overcome the effects of this medication and hopefully it will clear from my system soon. Update 1 month later: The anxiety/panic attacks took about 1 1/2 weeks to subside for the most part, but I am still having very minor attacks it seems which include throat tightness. I have been switched to Zantac as my reflux medication. F 24
20 MG 1X day
1/22/2012
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Patient History
 3  bleeding ulcer-h. pylori severe headaches, nausea with vomiting and dry heaves, tingling and numbness in hands and feet. I don't know for sure if it was the omeprazole causing the headaches, etc. because I am also on a preventive med (Amitriptyline) daily for the headaches and levothyroxin low dose for hypothyroidism, but I was hospitalized for the bleeding ulcer in Oct 2003 and have been on the omeprazole ever since and that is about when these sick headaches started. They are so bad they totally disrupt my life and I have never had headaches quite like these, I'm sick all day and night and then a whole day after to recover from that. So I've been off the Prilosec for about ten days now and so far no headache but it's too early to tell but will keep updating as time goes by, whatever happens. I am still having the numbness in fingers and toes and since that involves circulation and vascular issues it may be awhile to determine what that is about. I hope this may help. I'll be back with more in the future. F 53 8 years
20 1X day
1/16/2012
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 3  Acid reflux Slowly developed and maintained stiff, achy neck and uncomfortable mouth sores. I read the Mayo Clinic webite where it stated mouth sores are a rare but possible side effect as well as muscle (neck) tightness and pain. The med worked well or my reflux, but these side effects are too miserable to permit me to continue. Now I try a naturopathic remedy: when I feel reflux, I eat a pickle! The acid in the pickle fakes out my proton pumps to think they've produced enough acid, I suppose, and the reflux symptoms vanish! Tried on 3 other people with success. F 47 8 days
40 mg 1X day
1/10/2012
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 3  Gastritis I have had anxiety that cannot be controlled even when I stop worrying. I don't actually have panic attacks but just begin to shake A LOT when I have a worrisome thought. I keep feeling like I'm getting better but Prilosec keeps bringing me down to states of anxiety. It's not worth it. If you have gastritis, be careful about what you are eating for a while and address the anxiety, stress, mental side of the problem if there is one. Don't let your doctor put you on this and forget about you. M 17 2.5 months
20 mg 1X day
12/17/2011
 3  Acid reflux/ GERD All over muscle twitching, stiff neck, sore joints, tingly hands. However it has helped alot with the reflux/gerd. I like that it works but dislike the side effects. F 26 7 days
20mg 2xday
12/6/2011
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 3  Acid reflux Weakness in back of legs and arms, faint feeling, unsteadiness, palpitations, trouble swallowing. I was put on Omeprazole four years ago for acid reflux and have taken it sporadically ever since. I find that if I take it for more than a day at a time I seem to be having unpleasant side effects, the worst of which are this strange weakness in the arms and legs, plus feeling that if I go outside or into a shop I'm going to keel over. Am going to try not taking it for a few days in a row now to see if there is any improvement. Not too happy with the side effects. F 44 4 years
20mg 1X day
11/23/2011
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 3  GERD Leg pains, stiff sore neck, gas, anxiety. F 36 10 days
20
11/21/2011
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 3  gastritis/acid reflux The side effects were dry mouth, upper left abdomen pain, gas, insomina and burning lips at times. Headache too. It may have helped but the side effects - I am just not that brave a warrior. F 41 14 days
20 mg 1X day
11/15/2011
 3  Acid reflux/gastritis dry mouth, burning lips, headache, insomina(I would only sleep a few hours a night), mood swings, anxiety (to the point that I just said forget it - when you start thinking about throwing a stapler at someone, about people coming to hurt you, having a wreck, etc. and you didn't do it before the medicine, and it started the day you took the medicine, well...) fogginess, flu like symptoms I was having major reflux - that included palpitations, etc, gurgling and pains and burning in the stomach. They told me I had a UTI and a sinsus infection - gave me Zpack first (horrible reaction to that), then they gave me Cipro (GROSS) and I got off that and started the prilosec. IT could be that the 20 mg was too strong a dose for me - and it seems to have knocked out the gas and palps, but the anxiety just got to me. I go back to my doc on Thursday. I just am medicine phobic because every time I take something - I get weird reactions. Hoping these side effects go away SOON! Funny thing is - I had the burning lips when I took Zegerid too. I do have thyroid problems and I take synthyroid and perhaps this has been inhibiting my medicine - we just adjusted that a little - and hence more anxiety, i am sure. Just not going to take this unless I am seriously ill. Would like to know from other people about the anxiety - if it really made them more anxious or if it just what people say here? F 41 5 days
20 mg 1X day
11/14/2011
 3  GERD, IBSC,Hiatal Hernia,Gall Stone Heart racing and jumping, nausea, dizziness, depleted vitamin B 12, pain in legs, feet, hands,fingers, back, hip, really bad weight loss,hair loss,belching,acid back up in mouth,pain in left abdomen, bloating,bad,constipation, bad dreams,anxiety,crying sometimes,atomach pain severe,headaches, neck ache, feeling like I am geting worse,still cannot eat, or drink without pain, and tightness in middle of stomach.Dry mouth gums tight, swelling sometimes.blurred vision.Cannot sleep, either.weakness,tiredness. It helped a little to calm the stomach down, to reduce the acid which is still there so i could eat a little bit but cannot eat meals, or drink a lot of juices or water or hot drinks without burning, and acid coming back.Although, if i don't take it i end up in the ER, with acute esophagitis, and GERD, so bad i could die.I do not drink or smoke, eat healthy small small meal only 1 or 2 a day. tightness is bad, and food won't go down or digest, but without Prilosec, the burning inflamed insides return.Don not know what to do doctor tells me do not stop, other doctor said don't take it anymore.Then what do I do for my condition? F 65 5 years
20 MG 1X day
11/12/2011
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 3  GERD Night sweats, waking up night thinking I was dying, anxiety, depression, sense of doom, loose stool/diarrhea Has helped with the GERD. Prior to taking Prilosec was regurgitating in the mornings (3-4 times a week). Waiting to see if side-effects linger. M 38 10 days
20MG 1X day
10/31/2011
 3  Ulcer/GERD Belching/Depression/Mental Slowness/Heightened Anxiety The first 1 1/2 weeks of taking Prilosec, I felt better. My MD prescribed 2 doses of 20 mg per day, and the one day I took both doses, I felt a major mental slow down. I had to focus to remember what my train of thought was just 10 minutes prior. After about 12 days of the medicine, I had a MAJOR panic attack to the point that I refused to go out in public with friends. Before starting Prilosec, I had anxiety, but NEVER to the point of crying and refusing to go out. 1 week later I stopped Prilosec, and I had a major LOW mood swing. I started up on Prilosec a few days later because I had severe intestinal pain, but by Friday I once again felt some anxiety and depression with what I refer to as hyperactive thinking - I just kept thinking of things that upset me and gave me anxiety. I seriously thought I was going crazy... Then I realized I never had it this bad before. So this last Monday was the last time I took Prilosec because about 3 hours later I had mini panic attacks for ABSOLUTELY NO REASON. I'm not certain that the medication is causing it - but it is definitely exacerbating any issues I've had in the past, and I shouldn't have to deal with it if I don't have to. I have now been off of Prilosec for 3 days, and while I've still had major mood swings (mostly LOW swings), I feel like I am getting better. I cannot say HOW RELIEVED I feel to know that others have felt the mental side effects because I seriously thought for a few days that I was going crazy. F 23 4 weeks
20 mg 1X day
9/15/2011
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 3  acid reflux update i posted recently about my conditions from taking prilosec for 6 years. after almost 2 weeks off the drug normality is coming back,no more night fevers no more panic attacks i still have the tingling in my forhead and right arm but slowly subsiding. my personality has done a 180 my friendlyness is back going out with my friends more and no more dread. i still have an emotional episode once in awhile for some reason my sensitivity to certain things must have been exagerated while on this med but im sure it to will subside.im glad im getting back to normal the feeling is like being in my 20's again. i have been using tums as a temp replacement not eating late and drinking lotts of water seems to help but i would rather have the heartburn that all of the side effects for sure !!! M 41 6 years
20 mg 1X day
9/12/2011
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Patient History
 3  Esophageal Stricture depression; brain fog; general feeling of "blah"; not much trouble swallowing anymore.... I've had trouble swallowing (feels like food/beverage stuck in throat) since I was a teen. I am now 45 & one night a few months ago food got stuck so bad all I could do was gasp - my husband had to hit me on the back to get the food out (he has since learned heimlich). My dad had hiatal hernia & brother had esophageal stricture so I went to the doc and sure enough I had esophageal stricture. The doc stretched my esophagus during the endoscopy and put me on prilosec forever. I have been told that I have to take this med or possibly face esophageal cancer in the future due to acid. I NEVER have heartburn. After reading about other people w/the same side effects, I think I will be getting a second opinion. The doc also told me to raise the head of my bed - haven't tried that one yet. F 45 2 months
20 MG 1X day
8/11/2011
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 3  Acid Reflux & Stomach Pain Broke out in hives on lower half of body. NEVER had any signs of hives in my life. It works. Helped on the stomach and acid reflux even after 5 doses. Will have to find something else though since the hives are scary. M 37 5 days
30 MG 1X day
8/5/2011
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 3  acid reflux shaking, numbness in arms and legs, heart palpitations, increased anxiety, constant fatigue My doctor put me on this drug to control my constant acid reflux. I have been on it for maybe six months or more and have just started to have these symptoms. I have been to the ER four times in the last six days with the same symptoms and all the usual tests have come back normal. After reading others complaints, I can only deduce that my long time on this drug has caused these effects. F 31 6 months
20 - 40 mg 1X day
6/18/2011
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