PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Acid reflux I feel completely sad, headaches, I have phlegm in my throat and cough with wheezing taking Atrovent for it to see what I have meanwhile I see a pulmonologist. X Ray are fine and blood exams fine. This drug has me depressed and I'm so hyper and pumped always. No sex drive whatsoever.... I'm very strong mentally... this isn't like me. When I take it I feel annoyed want to be left alone and not talk to anyone. I get annoyed by my husband poor guy. I feel like everyone is bothering me and I get sad bad thoughts. It's really horrible to be honest. They don't even know if my cough is in fact reflux Lol! I been with a 5 month cough from prednisone to albuterol, benzonate, doxycycline , zythromax , mucinex, home remedies, steam with anamu plants and steaming to bring out phlegm , honey tea lemon .. you name it this fought began after a cold in the middle of pandemic but it was negative covid. I even had an inspector come to my house see if it's mold idk! I'm the only one like this. Before this year I was perfect healthy never needed a doctor. I am a teacher I teach from home. I have a daughter my life is good ... no one knows why I'm coughing yet but this medication needs to go... it makes you feel worse. Forget it F 29 1 months
40 1X day
11/27/2020
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 1  Upper GI Bleed/ Ulcer Worst god damn drug. How do they even get this sh*t FDA approved. I was prescribed this after I had an upper GI bleed from an Ulcer. Literally from the day I took I started feeling dizzy.. Day 2, bouts of depression and crying, overwhelming anxiety and random pains in the stomach area. I couldn't sleep for the few nights I took this and when I could get an hour or so of sleep I would jolt myself awake. DO NOT TAKE THIS IF YOU CAN AT ALL AVOID IT. M 40 2 days
20mg 2X day
11/18/2020
 1  Reflux asthma severe depression, severe anxiety, panic, agitation, confusion, rapid thoughts, social nervousness, fatigue, feeling very cold, lump in throat, mild sore throat, increased stomach pain My asthma doctor prescribed this to see if it'd lessen my need for my rescue inhaler from attacks I get after eating and I wish I wouldn't have touched this stuff. I already have depression and social anxiety and adhd-type symptoms, but have been relatively stable lately and all that changed 2 days into taking this. Wasn't sure at first if it was the medication until I started googling reviews. I've been feeling like I'm losing my mind. I haven't noticed a significant improvement in my ‘reflux' since I never have heartburn, though I haven't reached for inhaler daily like I was before. It's definitely not worth it and I'll just stick with my inhaler. Glad I got on here and read through some of these reviews so now I know it's not just me. It's crazy that a medication like Prilosec can cause so much emotional trouble for someone in four-days' time. F 29 4 days
20 1X day
11/13/2020
 1  Possible ulcer/mild gastritis Night sweats, heart palpitations, insomina (woken out of sleep), rapid heart beat, bloating, restlessness, loss of appetite I went to the ER with extreme nausea systems, I had intermittent nausea for about four weeks prior, a bloddy stool(once), and dull burning upper abdomen pain for about six months. They put me on an EKG, X-rayed my chest, blood and urine, all normal. Then they pumped me with metoclopramide along with other antacid meditcations. I was on a prescription for omeprazole for two weeks until this past Tuesday. I haven't had a full night sleep since. When I laid down my heart would be pounding and if I tried to close my eyes I'd immediately be awaken with rapid heart beat and a feeling of an adernaline rush/fight or flight feeling. I've had higher resting rate rates since. I can't sleep for more than three hours on a good night some nights it's up every hour and a half. It's been 48 hours since I've taken my last dose and I've started to sleep more hours of the night but the sleep is still broken up. I had a three night span of a total of 5 hours sleep. Anyone with similar reactions to being on Omeprazole and how long it took you to get back to normal sleep. M 35 14 days
40-80 1X day
11/6/2020
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 1  acid abdominal pain M 68 56 days
2X day
11/4/2020
 1  silent reflux pins and needles, twinges, twitches, burning feelings in hands, arms, legs, feet, sensitivity to cold, tense/ tight muscles, brief occasional stabbing pain, pricking/ prickly feelings One day, 2 weeks ago I started having pins in needles in my hands, arms, legs, feet. By the end of the day I was worried. Checked my medications and saw that Prilosec can cause pins and needles. So I stopped Prilosec the next day. Pins and needles abated a little, but soon new symptoms appeared in addition - burning feelings in legs, feet, arms and legs, twinges primarily in my legs, muscle tightness in my upper arms and legs, sensitivity to cold in my hands and feet, very very slight tremors in my hands, occasional brief stabbing pain in ankle waking me from sleep/ strong pricking feelings. Feelings of muscle weakness but I don't think I've actually had any muscle weakness. Everyday is different. Worsens at night when lying down. Had bloodwork done to check for vitamin and mineral deficiencies and all blood work came back normal. My ENT and PCP had not heard of these symptoms of Prilosec withdrawal but my neurologist had. Thankfully! He asid that Prilosec can cause an "inhibition of vitamin B12 absorption" and can cause "sensory symptoms." He said that even if the bloodwork doesn't show a vitamin B12 or B1 deficiency, my body can still be having a hard time absorbing it bc of the Prilosec. He is having me take vitamin B complex (vitamin B12 and B1 were the ones he specifically mentioned) for the next 3 months and expects me to have a gradually improvement during that time. He also evaluated my balance etc and since that was all fine, he said my sympto F 41 4 months
40mg 1X day
11/3/2020
 1  Acid reflux First time anxiety - feeling the end of me Helped my acid reflux at higher cost M 40 1 days
20 1X day
10/30/2020
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 1  Acid reflux Tremors, SEVERE anxiety, sore throat, dizziness, fatigue, numb hands and face, bad stomach cramps, back aches. M 27 6 days
20mg 1X day
10/29/2020
 1  GERD Extreme leg, Ankle pain. Started on day four in the middle of the night. Took one more dose and decided to stop. I'll never take this drug again. It's been 36 hours since I stopped still have the leg pains hoping this resolves quickly F 66 6 days
20mg 1X day
10/23/2020
 1  GERD Extreme aching both legs, ankle pain, hamstring tightening My symptoms started on day 4 in the middle of the night. Took one more dose and decided no more! It's now 36 hrs since my last dose . Legs feel miserable still. I hope it resolved quickly. I'll never take it again. Scary stuff. F 66 6 days
20mg 1X day
10/23/2020
 1  GERD Extreme aching both legs, ankle pain, hamstring tightening My symptoms started on day 4 in the middle of the night. Took one more dose and decided no more! It's now 36 hrs since my last dose . Legs feel miserable still. I hope it resolved quickly. I'll never take it again. Scary stuff. F 66 6 days
20mg 1X day
10/23/2020
 1  Stomach pain UPDATE: I have posted on here before several months ago suffering from all of the same nasty side effects as everyone else. After nearly 6 months of dealing with these issues, I have learned the following: The initial wave of side effects does subside after several weeks however some (chest pain, brain fog, heart palpitations, and lightheadedness) persisted. Every numerous tests/doctors, I finally found a doctor who listened to my complaints and put me on an elimination diet. Turns out I have now developed a corn and soy intolerance. I'm convinced it is from the Prilosec destroying my gut bacteria. Anyway, now that I have eliminated both (not easy in today's processed food society), I feel like my old self. Those still suffering, talk to your doctors or do your own research and look into food allergy/intolerances. M 33 14 days
20 mg 2X day
10/20/2020
 1  Heartburn Vertigo!!! It was awful!!! Prilosec depletes your body of vitamin B12 which is needed to digest food & causes vertigo. I'd rather deal with heartburn than feeling like I'm spinning for days & vomiting. F 50 3 days
20mg 1X day
10/16/2020
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 1  Acid Reflux Anxiety, Insomnia, Depression, Heart Palpitations, Hot Flashes I found this site in search of comfort. I was looking for some clarity on how long people experienced the side effects. I was supposed to take for 30 days. Only took it for 20 days then started having anxiety and sleeplessness. I didn't link the 2 together I really stopped taking the MED b/c I was on it for throat irritation and felt like it had cleared up so I stopped. It just so happened it was around the same time the sides started. Let me first start by saying I am an excellent sleeper and can normally not even make it through a movie without falling asleep. I can usually take naps no problem and could sleep 10-12 hrs if I didn't have to get up. When I was on vacation all of a sudden I started waking up for no reason(this was about 20 days on the MED) 2-3 times a night. I would wake up feeling hot, and kind of in a panic and felt claustrophobic. I was usually able to get back to sleep. I attributed to not being in my Some things I tried- Drinking Chamomile Tea before bed, melatonin, benydryl, magniesium, b12, b6, multivitamin, CBD oil On about the 2-3 week after stopping the MED I would still wake at night every 1-2 hrs. but would be able to go back asleep within 30 mins or so, I would still feel hot, the anxiety was lower but still intermittent. I was still not anywhere near my normal self but it was more tolerable as I could get some decent sleep and function the next day. Wk 4-6 I cont. to wake less freq. and would be able to get back to sleep within 10 mins. The anxiety was gone mostly After Wk 6 I felt like I was back to normal. I started sleeping through the night, could take nap during day, had no more waking up feeling hot, and no more anxiety. Also I have never had any sleep or anxiety problems ever in my life. I am not sure if any of the vitamins/ meds listed above helped decrease the amount of time to help me get back to myself or not. It could be that your body just needs time. I was willing to do about anything during the 2 worst weeks. I went to a sleep doctor (who just told me I had a sleep maintenance insomnia from anxiety). Anyways it looks like I am back to normal and hopefully no long term effects will be done. But this is a NASTY drug and I will never take again. I hope this helps someone in the future to give you hope that you will get back to normal with time. I had some long and miserable days of wondering if it would ever end. Best Wishes M 37 20 days
40mg 1X day
10/14/2020
 1  Misdiagnosed Gerd Horrendous rib pain, unable to move by the end if the 3rd week. Chest tightness, difficulty breathing, heart palpitations. Anxiety, horrible brain fog. Dizziness, tiredness, swollen toes, hiccups. Abdominal pain. This medicine is hell itself. Terrible side effects, horrendous pain. I am 2,5 months off of it and still not normal. Things have gotten much better but its still horrible. I have acid coming up at night giving me sore throat, chest tightness, difficulty digesting food. I lost 15 lbs in 2 months. This stuff is poison, the worst kind. Do not take it! F 35 3 weeks
40 1X day
10/14/2020
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 1  GERD/LPRD I started Prilosec at 20 mg once a day from my PCP (slight acid reflux) and then ENT increased to 40 mg once a day because I started having a lot of burping and feeling of something stuck in back of throat (looking back I think this was a side effect of Prilosec). I then was referred to GI because I was having a feeling of gagging and burping SO bad. GI increased to 40 mg twice a day and two days later, I had the first panic attack of my life. I've never had issues with mental health but felt like I couldn't sit still, think straight, and SO much anxiety. I didn't even know what anxiety felt like until I took this drug and they increased my dosage. I then googled prilosec and and anxiety and came across this page. I immediately stopped taking because I knew this drug was causing all my problems. I have been off Prilosec for a little over 3 months now and truly 3 of the hardest months of my life. I was so sick after coming off this drug. It really messed up my digestive system and I got blood work done and my B12 was incredibly low. Every month coming off this drug I continue to feel better and like myself again. I now tell everyone I know to NEVER take this drug. I was so dizzy, nauseous, diarrhea, no appetite, tingling in my face/hands, felt like everything good I had was disappearing and the worst anxiety/depression (something I'd never felt in my life). I had a colonoscopy and endoscopy last week and everything was completely fine, so reassuring to know nothing is actually wrong. Best of luck to anyone taking this drug and recommend if you have any side effects get off ASAP. It will get better, it does take a lot of time. F 28 3 months
20mg/40mg 1X day
10/12/2020
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 1  Burning acid/indigestion Lightheaded first time I took it. Felt anxious, but did not relate it to the medication. Acid resolved in 1 hr. after taking it. Acid controlled for two days, then it returned. I took a second dose. Controlled acid in 2 hours. Lightheaded again. I then also began suffering from full anxiety attacks, heart palpitations, crying spells, nausea, brain fog, and ears ringing. It has been 5 days since I last took it, and I am still suffering. This is torture!!! If anyone knows how to reverse these effects, please contact me. I am in agony!!! F 40 2 days
20 1X day
10/5/2020
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 1  Gerd/heartburn/acid reflux SEVERE ANXIETY. Panic attacks. Insomnia. Chest palpitations. Forearm pain. Limb pain. Chest pain. Stiff neck. Neck pain. I started Prilosec/omeprazole 5 years ago when I started having acid reflux in my throat at night. I've had anxiety and panic disorder for years not tieing the two together. I had no intense symptoms until recently when they upped my medicine to 40mg. I started having severe anxiety, not being able to sit still. Irritable. Panic attacks at night. A adrenaline like shot waking me up in the middle of the night out of deep sleep with pounding heart racing heart and heart palpitations. Night sweating. Stiff painful neck. Tightness around throat in front. Forearm pain. Headaches. Head pain. Blurred vision. I'd rather deal with the horrible gerd and heart burn then go through this hell again! Horrible should be recalled and never put back on shelves! How do they get by with feeding us this poison! F 29 5 years
40mg 1X day
10/5/2020
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 1  Stomach Ulcer Extreme fatigue, heaviness in arms chest, jolted out of sleep, anxiety, panic attacks ,tingling in legs, twitching, depression, hopelessness, lack of good emotions, crying, heart palpitations, I am writing this for my husband, am so relieved to find this web site, I thought he was losing his mind so did he! His first symptons showed after 6mths of taking Omeprazole (UK) he was not given any advise on how long to take the meds, with tingling in legs, a visit to the Dr blood samples ruled out everything but a slight increase in iron levels. He then went through a whole array of side effects. He found taking valerium and magnesium helped with his night jolts, sleep and twitching in limbs . After 10 months he stopped taking his meds and things started to improve. Unfortunately after 2 months he had symptoms of ulcer and started taking omeprazole again. This time his side affects were instant! Hes weaning himself of the omeprazole and we are now looking at alternative solutions to manage his acid levels. It's strange and am angry that his Dr had not picked up on his side affects and prescribed an alternative med., all of this could have been avoided. I cant wait to get my husband back to his normal self, hes not the man he was, 2020 has been a living hell for him. M 57 10 months
20mg 2X day
10/1/2020
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 1  Suspected getd Anxiety, chest pain, stomach cramps, random cramps around body. Sleeplessness, irritability, random crying spurts. Moments where I feel fine then BAM heavy chest. Please dont take this if you have history with anxiety. Even if you dont. Itll mess you up. F 23 6 days
20 MG 1X day
9/29/2020
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