There are 874 ratings for the drug: PRILOSEC in the Askapatient database.

The average rating for prilosec is 2.3.
Results are sorted by Gender with males listed first.    
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Key to ratings for prilosec:
5-Very Satisfied: this medicine cured me or helped me a great deal.
4-Satisfied: this medicine helped.
3-Somewhat Satisfied: this medicine helped somewhat.
2-Not Satisfied: this medicine did not work to my satisfaction.
1-Dissatisfied: I would not recommend taking this medicine.

                    
Page: 1  2 3 4 5 6 7 8 9    Results are sorted by Gender with males listed first.
Rating   Reason Side Effects Comments Sex Age Time Taken
and Dosage
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 5  acid reflux slight headache at first, then none at all I suffered from acid reflux for 15 years or more and tried everything you can imagine, nothing worked- Prilosec has worked curing my acid reflux symptoms 100%! It really has changed my life. M 35 6 months
4/28/2001

 5  heartburn initial headache and minor stomach pains it is very effective but expensive M 63
12/22/2000

 5  Gastro-esophageal reflux disease None Suffered from GERD since childhood. Tried several OTC drugs, with no relief. Gastroenterologist prescribed Prilosec approx 7 mos ago. Never again have I experienced a single stomach pain. M 20 7 months
6/19/2001

 5  Advil side effects Discolored stools Taken to protect my stomach from all the Advil I consume. Wash two of these down with some Maalox liquid before bedtime. My nighttime reflux is gone, and no more ulcers from the ibuprofen. Aside from funny looking poop (two-toned like marble rye bread), I have had NO side effects with any PPI, including omeprazole over the counter. You'll find a lot of selection bias here - people with no side effects don't come here to comment. I'm only here because of my experience with Zantac and thought I'd come over and leave one about Prilosec, too. M 45 1 years
40mg 1X D
2/18/2010
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 5  acid reflux None. Wouldn't take anything else. M 48 5 days
20mg 2X D
3/6/2010

 5  daily heartburn none at all I was taking a daily dose of Zantac which moved to two to three doses daily to control the heartburn. Decided to try something new and I'm glad I did. On this site to see if taking it longer than recommended would be a problem and I have found enough positive comments to assure me that I can use this as I did the Zantac. I probably will cut the pills in half but would consider this medicine a rousing success. M 53 20 days
20 1X D
4/1/2010

 5  acid reflex / flap doesn't close Well although i do have some of those side effects i have never attributed them to prilosec/omemprisole. I have always called it the miracle drug. I have tried many of the others, and NOTHING has helped me as much as this drug. I do have an anxiety disorder and i have join aches/pains etc. But I am 60 years old too. I will try changing to something else for a few days/weeks and see if anything changes, but i doubt it. I have had GREAT luck with it. M 60 20 years
20mg 1X D
4/3/2010
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 5  Gastric ulcer absolutely none and I have IBS.no headache no diarrhea no muscle pain M 56 4 years
10mg 2X D
4/5/2010

 5  GERD None I am concerned with long term effects. Especially after reading comments posted herein; however, I can illustrate NO adverse effects. I have joint pain (but had it before treatment). I run 5 miles 3x per week, and weightlift 3x per week. I have noticed no ill effects. I have tried stopping, but experience GERD after about the 3rd day off treatment. I tried H3 blockers. They work, but require increasing dosages after time. M 53 6 years
20mg 1X D
5/12/2010

 5  Very strong heartburn None I really do love this stuff. I had such bad heartburn that sometimes I would wake up violently at night gasping for air. I used to have to take upwards of 10 tums a day until a doctor told me about this stuff. I have no heartburn at all anymore and will continue to take this as long as I live probably. I might cut down to once a day soon, I think that will probably be fine but doctor recommended this dose for now. M 45 1 years
20 2X D
5/15/2010

 5  acid reflux, heartburn, etc. None I tried Nexium, but my insurance company wouldn't cover it, so I went back to Prilosec. Not certain about the dosage, but have been taking the standard Prilosec OTC for the last 10 years or so, with no changes in effectiveness. M 67 15 years
20 1X D
5/27/2010

 5  Gerd Very minimal if any. I got more side effects from Rolaid's. I tried all of the antacid's available at the time and still had indigestion and GERD problems. Prilosec (Omeprazole) solved all of the indigestion and Gerd problems immediately. I didn't like the high prices at the pharmacy so living in San Diego I drove to Mexico and found it for $79 for 180 20gr capsules. I moved and now buy it online from (pharmacymex.com). It comes from Mexico City and takes a couple of weeks to arrive. I use my Visa card and have never had a problem. If you are going to use Prilosec you may as well save lot's of money. You can use the savings for pepperoni pizza ;-) and de-fuse the indigestion misery. M 63 7 days
11/27/2005
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 5  Acid Reflux Couldn't explain sudden onset of migraine-like headaches - taking me out for entire days at a time. Lot's of Ibuprofen (about 600-880mg) was the only thing I could do that helped. But the headache was then dull. I had suspected that this might have been the Prilosec since it's the only systemic thing that has changed in my diet/life. I thought maybe I had a gas leak in the house because the headach was sooo bad. Guess I'll keep using the Prilosec and see if the headaches fade - it's worth the acid control it provides. ALSO noticed that I get hungrier and have gained 10 pounds in two weeks! Wierd. M 42 14 days
9/8/2005
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 5  Acid reflux dry mouth, thirsty, usually only on the day I take the pill I was having acid reflux mostly at night, usually only when I had eaten within about 2 hours of going to bed, but did have occasional symptoms during the day. Following suggestions found here and elsewhere, I started with 1 20mg per day, then to one every other day, then tried 1 every 3 days. Taking them in the morning, on the 3rd evening, I experienced mild acid reflux at bedtime, so I switched to taking them in the evening, around suppertime. Now on the 3rd day, I have no reflux at all. M 49 3 weeks
9/13/2005

 5  acid reflux I have yet to determine a side affect from this drug. I was fisrt introduced to this drug by a Gastrenologist in 1993. This was when acid-reflux was fisrt being recognized. I began this drug and was taking 30mg twice daily for about 3 years. I now take one 20mg O.T.C every morning. I cannot go one day without taking it. It is an absolute life saver!!! I have had one bout with h-pilory bacteria, which is caused from the prilosec and is treated with pepto bismol 3 times a day and antibiotics. Which is no fun. M 36 13 years
9/5/2006
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 5  GIRD Nasty headache for a day when starting or restarting if off for more than 2 days. No other side effects noticed, but am concerned about calcium loss. It works great. Got rid of my GIRD cough and stomach pain. The recent (to me at least) information about calcium absorbtion has me wondering if its effecting my teeth. My dentist recently had to replace two crowns and said the tooth under the cap was spongy. M 54 3 years
12/31/2006
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 5  Acid reflux/Acid indigestion This stuff is INCREDIBLE !!! Ilived 24/7 with heartburn (usually accompinied or followed by nasua and vomiting). Life was HELL !!! I was having to resort to a couple of tablespoons of baking soda in water almost every day - Uck !!! This stuff started working the first day even though is said 2 to 3 days before I would notice anything. I won't stop taking it now. My sinuses are very dry but I'm not sure if this is somehow related. Anyone else have this slightly negative effect ? I've tried Tums, Pepcid, and Zantac 75 - this has all of them beat Hands down. M 46 3 months
11/27/2005
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 5  Chronic heartburn None Without it I couldnt survive! I take 1 each day and it seems to do the trick. Sometimes I pop a few tums right before I lay down if I have a late dinner to help. But otherwise I dont know what I would do without it! M 26 2 years
8/26/2006

 5  reflux Appearent increased sensitivity to heat/humidity, and hot drinks Works much better than antacids, very happy with results M 49 2 weeks
2/17/2006
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 5  Hiatus Hernia So far, I have not seen or feel any side effect since I have start using this medication. The pri-losec is the best medication that can be used to cure the Hiatus Hernia effects because I have been suffering the acid reflex for a long time and non of the heartburn medications worked out only the prilosec. M 40 2 days
12/14/2006
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 5   After one year of taking it everyday I've had some serious side effects like diahrea and stomach pains. M 1 days
7/13/2005

 5  GERD Occasional stomach pain which is brief and goes away. Prilosec OTC worked every bit as well for me as precription Nexium, but cost significantly less. And it worked much better for me than Zantac. I've been on meds for GERD for almost 7 years now and for the last 2 I've used Prilosec OTC. It's been the best one for me. M 38 2 years
4/30/2007

 5  Frequent Heart Burn Non Worked in one day, I had been taking 4-5 antacids nightly before this M 45 14 days
4/30/2006

 5  acid, reflux Occaisional feeling of lump in throat, otherwise none. Great stuff for me. Taking OTC every day in times of stress and backing off to every other day whenever I can. Would eat 3-4 antacids and a OTC Pepcid, Zantac or Tagamet before supper almost every day before this. Recommended by my GI doc who said he has many patients who have been taking for years. M 52 1 years
8/20/2007

 5  Acid-reflux The only side effects I have had are when I stop taking it for a couple of days when I run out. I get headaches, nausea and general flu like symptons M 48 4 years
1/7/2007

 5  ARD - Have No Cardio-Sphincter Very recently had an acute swelling of both feet/ankles, progressed up to the knees. Hot to the touch. We thought CHF @ first (scared the hell outta me), but Low K levels were the only indicitive suspect. Upon first taking prilosec: minor to acute migraines, back of the head right at brain stem, basically...very occasional, but very painful with a duration of approx. 1-3 hrs each time. Have tried others out of curiosity, with little or no effective comparison toward general comfort. Unbeatable thus far, well worth the occasional "throbber". *note, small family history of migranes - but mainly the women* M 39 14 years
1/12/2007
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 5  Heartburn Nothing that I can notice and have been using for about a year. I have been taking this cause Im no longer on a HealthCare program and dont want to pay for Previcid. BUT - PREV is much better of course. Still my Dr. Said OTC is fine and just about the same. I can still eat all my spicy foods as long as they are not too late at night. I now get my PRI OTC from a Canada Shop and its much cheaper. I can get 150 pills at a time with OUT a prescription. M 41 1 years
6/17/2007

 5  heart burn/acid reflux no side affects after 5 years and feel great heart burn since i was a teen, always taking antiacids until they seemed not to work any more, started prilosec everyday when i wake up with no side affects,we've all seen the commerical with the glass of orange juice that would be like acid to most of us and especially me but i havent had that problem i years, chocolate, pizza, milk, greasy foods,really good itialian food was all the kiss of death for me when i was younger and these were my fovorite foods so i would suffer thru it but no more suffering, i've herd it causes hair loss? i still have all my hair! even after 5 years, M 43 5 years
10/10/2008

 5   None whatsoever. Have been taking it regularly for two years with no side effects. It's the only thing that has helped my heartburn. Tried lots of natural remedies, none of which worked. M 58 2 years
10/20/2008

 5  acid reflux No side affects at all. None that i'm aware of anyway. I take the prescription version, omeprazole. I take half a dose daily, 20mg. It has totally stoped my acid reflux. M 61 4 years
10/16/2008
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 5  scaring, reflux, gas. gagging no side effects stopped taking it, dont like anything that warns about liver problems, all symptems returned. 10 mg was all I needed was taking lipitor, and had liver elevated, dont know what was cause. its a jungle out there M 71 2 years
8/8/2004

 5  Severe Acid Reflux Must take medication for the rest of life. Miss just two days and reflux returns. M 65 15 years
3/7/2004
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 5  acid reflux none M 40 7 years
10/25/2002

 5  Acid Reflux Severe heartburn. Burning sensation upon lying down. Asthma and hoarseness/sore throat in the morning due to backup of acid. I never believed that I could eat basically anything, particularly a food with any amount of fat content and not think I was going die, prior to finding Prilosec. Tagamet and Pepcid were only pretenders. M 48 2 years
6/20/2002

 5  Acid Reflux None Severe heartburn. Burning sensation upon lying down. Asthma and hoarseness/sore throat in the morning due to backup of acid. I never believed that I could eat basically anything, particularly a food with any amount of fat content and not think I was going die, prior to finding Prilosec. Tagamet and Pepcid were only pretenders. M 48 2 years
6/20/2002

 5  Severe daily heartburn I have had a low blood count and elevated liver enzymes for several years. No physician has connected these symptoms with the drug, but I have no other health problems, and am in excellent physical condition. I honestly think I would have had several major surgeries for ulcers and erosion of the esophagus if I had not taken Prilosec. One 20 mg tablet a day and I am completely symptom free. The drug probably saved my life to this point. M 52 20 years
4/23/2007

 5  Acid Reflux, Gurd None so far, after 6 years of taking the drug daily. After running out a couple of times, the old symptons returned. That's about it. M 57 6 days
3/17/2007
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 5  GERD / Barrets Esophogus Have taken for 10 years; every few years when trying to get off of it I experienced typical rebound acid, bloating, leg cramps and vivid dreams; indeed Prilosec seems to suppress my dreams almost completely when I take it. Overall very effective at suppressing acid. Note: it is effectively the same as Nexium so don't waste your money on Nexium (or your insurance carrier if covered). Nexium was just a way for the manufacturer to profit on patent expiration of Prilosec. I sat in on a sales seminar for Pharma Salesguys, and it is only a few molocules different, only to get past patent expiration, and has no real differences from an efficacy perspective. Don't waste your money on Nexium and the marketing hype. Just take OTC Prilosec. M 45 10 years
6/6/2007

 5  Gerd & Gastroenteritis As I am also on maintainance dosage of Klonopin; a known interaction: increased sedation occured. My Psychiatrist & I are working with adjusted dosages of Klonopin as result. Other Side Effects: At first had headaches, some stomach pain and mood swings (maybe result of Klonopin interaction). These side effects have basically abated after 1 week of OTC/20mg 2x per day. What remains is feeling of lump in throat, pills feel like they're getting stuck in throat and some emotional irritability and mild flu-like fatigue remain. I took Nexium for 5 years until it stopped working; tried trial of Aciphex: agony! Severe stomach cramping and fatigue. Then, Prevacid: after initial headaches and stomach cramping & fatigue stopped acid but not consistently; bright yellow stool had me concerned. Despite Dr's. assurances about this my instinct said NO.....stop the Prevacid. It wasn't 100% effective with my acid anyway. So, I decided to try my last resort; Prilosec OTC: Stopped GERD completely. No acid! Just some side effects I'm hoping will stop after becoming more accustomed. My Gastroenterologist has ordered an Esophagram to be sure feeling of pills getting stuck is just feeling and not reality.....have read that most PPI's can also cause this side effect. I'll know more next week. Good luck everyone; I know how GERD can cause tremendous suffering; I have gotten the better part of the acid relief; now to fine-tune the rest. M 57 6 days
7/18/2007

 5  Acid Reflux Pretty major headache the first few days but it went away and hasn't been back. Completely stops my acid reflux. All symptoms are gone. Within 2 weeks my esophagus no longer felt irratated when I swallowed. I do have to stay on Prilosec continuously though, because if I miss a single pill, the reflux is back, with a vengeance. M 24 4 months
6/9/2007

 5  heatburn gas, Works great,I take it every morning and i can eat whatever i want.Tried numerous heartburn otc remedies.The only one that worked is prilosec. M 39 2 years
6/23/2007

 5  Severe acid reflux On-off diharrea, weight gain. I started taking omeprazole 17 years ago because of severe acid reflux I ignored until my esophagus shut down. Taking it changed my life. I cannot quit taking it but I have learned through the years that I can usually take 20mg every 2 or 3 days. After that simptoms return. I have gained about 40 pounds and have to deal with episodes of diharrea (I do not know if these are actually side effects because I have not been able to stop taking it). I have exercised more or less regularly. When I diet and only eat healthy food, I can usually space the 20mg to about twice a week, but not more. I also have noticed that I can take prilosec less often if I do not eat any wheats (no bread, pasta, etc). My main concern is not being able to lose the weight and would love to find out if this is related to the medicine. M 48 17 years
8/2/2007

 5  Acid Reflux None M 52 2 months
12/8/2007

 5  had stomach ulcer I HAD NO SIDE EFFECTS.AND ALL MY PAIN WENT AWAY. i AM NOW ABLE TO STAY OFF THE DRUG FOR DAYS. WITHOUT PAIN. UNTIL i EAT SOMETHING SPICY AND THEN i KNOW i HAVE TO TAKE A PILL. i NOW USE THE OVER THE COUNTER PACKAGES OF 42. THANK YOU PRILOSEC.KEEP MAKING IT . AND DROP THE PRICE SOON M 6 years
12/31/2007

 5  heartburn none This has truly been a MIRACLE DRUG for me and I buy the 42-count packages at Walmart without missing a single day! Can't live without the stuff now because I formerly would go to bed and as soon as I put my head on the pillow my heartburn would make me want to sit up again (took Tums by the handful before this!). Now I eat well and have NO HEARTBURN and NO SIDE EFFECTS. I would strongly recommend Prilosec to anyone! M 45 10 months
2/12/2008
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 5  GERD None. This has been a great drug for me. After 8 years, a recent blood test flagged me as Vitamin B12 deficient. Research showed that B12 is broken down from the animal proteins we eat, and the acid in the stomach is needed for this to happen. So does long term use of PPI drugs bring this on? I read where there is no hard connection of this as of yet. Am now taking a B12 supplement as of 4 days ago. M 44 8 years
2/15/2008

 5  Acid reflux, heart burn None, This produced the best results of any medication I ever tried. M 63 8 years
4/10/2008

 5  acid reflux No side effects I thought I was having a heart attack!! The doctor said the esophogus can spazm because of being irritated and feel like a heart attack. I take prilosec otc every other day. If I stop taking it, my reflux comes back after 3 days. I have tried to stop drinking coffee, alcohol, everything I was told to stop. Nothing worked. I won't stop taking prilosec, unless someone proves to me it is killing me. LOL. M 41 7 years
11/20/2008

 5  acid reflux No side effects I'm aware of. I have a history of esophageal problems, including having food stuck for up to 60 minutes (Shatzki's Ring) This was fixed twice by balloon dilation, but is likely to come back if I don't take a Proton Pump Inhibitor (PPI) daily. I took Protonix, another PPI, for 2 years but got tired of the $70 copay. I tried Omeprazole, which has a $16 copay on my plan, and it works about as well. I can drink caffeinated beverages, drink alcohol, and in general don't need to avoid anything, and have not had a recurrence of esophageal symptoms so far. If I were to have symptoms again I would go back to Protonix or one of the other expensive PPI's but so far so good with Omeprazole. M 70 2 years
11/29/2008

 5  acid reflux disease I usually get some gas and/or acid stomach late in the day about three hours before bedtime. I usually take three Rolaids Fruit flavor as an antacid. Sometimes I need the Rolaids Berry flavor for gas relief. This is cheaper than the Gas-X that I sometime use. I've taken Prilosec OTC everyday for over 6 years now. I can really tell after my lunch meal if I haven't taken it in the morning! My doctor had originally prescribed Nexium. After the pharmacist wanted to charge me over one hundred dollars for a thirty day supply, I knew I had to find something else for my acid reflux disease. Prilosec is the answer for me. I've sure saved a lot of money over the years, and it has kept my acid reflux in check! M 66 6 years
1/1/2009
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 5  Acid Reflux Lower back pain and neck pain I take 3 20mg tablets per day. Occasionally I get a batch of pills that cause lower back and neck pain. This pain was very common for me with Nexium so I switched to Prilosec and the pain went away. M 46 6 years
1/28/2009
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 5  acid reflux decreased acid reflux Idk where these reviews are coming from but I have been taking this for 2 years now and have not experienced any of these symptoms, it works very well compared to similar products. M 21 2 years
7/14/2008

 5  GERD None I have been taking 1/2 pill for 6 years with excellent results. One must remember that millions take prilosec with great results. This site is mainly visited by those with negative results tnat may or may not be from prilosec. M 55 6 years
3/12/2009

 5  acid reflux None I have always been an anxious person so in no way can i attirbute that to the Prilosec OTC. I started taking Aciphex but the doctor kept wanting to see me every 6 months which made no sense since the situation was the same everytime... i still needed the meds because my heartburn would come right back if i stopped taking it. Instead of just renewing my prescription i had to keep going in which was too much. Switched to Prilosec OTC and have loved it for about 8 years. Heartburn still comes back if i forget to take it for a day, so i need to stay on it. Hard to believe people have such severe mental side effects. M 28 8 years
3/19/2009

 5  Acid Reflux Side effects have been rare. Occasionally I experience headaches but I am not sure they are directly related. I do notice some flatulence but I don't know if it is related to the drug or just my age. In any event, it is not excessive. When Prilosec first came out, I was taking generic Zantac before bed or before eating spicy foods. My doctor suggested I try Prilosec. Since they were quite expensive at the time, I tried a half tablet each morning and found I still got all day relief. I told my doctor about it and he said if it works to continue. I asked about the 14 day warning, but he said with a half tablet I should be OK taking them indefinitely. He said the warning is for those who do not tolerate this drug. I ask about continued use each time I go in for medical visits. My new doctor concurs that it is safe to take in half-tablet form and can be effective for most patients. If you are on a limited budget, you might try a half tablet to see if you continue to get relief. M 62 5 years
7/18/2008

 5  GERD Just gas. Does anybody know if Beano helps? This is the only drug I've ever taken on a regular basis, and I like it and think it's effective. M 53 2 years
7/18/2008
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 5  GERD None. I've been taking 20 to 40mg Prilosec each day for many years (10?)and it has stopped my GERD symptoms completely. Acid reflux starts again if I miss a dose. I've not had any side effects and I'll change my doctor if she tries to take me off of it. M 66 10 years
8/6/2008

 5   No side effects what so ever. I have been using Prilosec for about 3 weeks, and have had no side effects. I decided to test it out on a double slice of pepperoni pizza today and was surprised that what would usually be the kiss of death for my stomach resulted in no heartburn. I love this medicine and take it within 5 minutes after waking up in the morning with no side effects what so ever. After waking up from an endoscopy procedure after being told I had very bad acid reflux, my doctor answered my question of, “ how long will I have to take this medication?”, by saying , “forever. I don’t know if I want to be on this med indefinitely, but for now, it has been a godsend. M 50 22 days
8/24/2008
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 5  heartburn possibly increased blood pressure I think Prilosec OTC is very good. I took the standard 14 day regimen, and have had no heartburn since I started. I have had heartburn since early 20's and tried many things. Zantac worked fairly good until the last year, when it started seeming ineffective, and I started using Rolaids and/or Tums with the Zantac. I don't know if Prilosec will continue working now that I finished the 14 day treatment. I feel hopeful. I had no side effects except for possible elevated blood pressure. I had not had mine taken for a couple of years, so I don't know what is normal, but it was up a bit over the last time. This may or may not be a side effect of Prilosec M 50 14 days
4/18/2009

 5  GERD NONE I've taken Omeprazole for over 10 years and have never had a side-effect. And it totally relieves the heartburn. It's a wonder drug M 60 10 years
12/27/2009

 5  GERD None that I know of... Used asiphex for many years, until I lost my insurance, this was recommended, and has worked great for the last 5 months. M 54 5 months
1/12/2010

 5  Excess acid production None I am 52 and I have been on Omeprazole 20mg for over 18 years now. I started when it was only available as Losec / Prilosec but I now have generic Omeprazole. It completetly changed my life for the better. Pretty early on I found that taking the 20mg every other day worked best for me unless I feel I have a particularly acidic reaction to some food in which case I just take an extra one. So dosage has remained stable and effective for 18 years. I can say hand on heart that I have been lucky enough to experienced absolutely no side effects. However, I know that I would not now be able to give the drug up. After so many years my body is so used to the regular drug that if I was to miss, say, three days I would get an uncomfortable reaction - But I am quite happy to stay on it for the rest of my life and have no worries. I felt I should post this because you always get lots of negative reation posted on the internet making people frightened and I wanted to provide a positive side - this drug worked wonderfully for me and after 18 years without a problem I think it will continue to do so. M 52 18 years
1/18/2010
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 4  Acid Reflux After 2-3 years on Protonix, then 6 years on Prilosec, I hurt my back about 3 years ago and never really healed. I have recently started having pain under rib cage on the right side, like a kidney punch. I have had the weakness in hands as mentioned by others as well. I do not know if I can attribute these symptoms to Prilosec, but I am going to try getting off it for a while. This was absolutely fantastic for acid reflux, but if the above are side effects, I will take a lot of Tums instead. M 38 9 years
10/17/2009
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 4  Gerd Extreme weekness. Tingling in hands, legs and feet. Frequent headaches. Some muscle cramps and twitching. Doctor finds nothing wrong. Product works as advertised. Recent research has shown a link between long term use and B12 deficiency because of the reduced acid in stomach ( check WEBMD consumer info on Prilosec). B12 deficiency causes these nuerological symptoms. Just started taking sublingual liquid B12. Too soon to tell difference. If this does not work will see about injections. Wish I could stop taking Prilosec but heartburn is fierce without. M 45 10 years
5/22/2009
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 4  Esphogis protection/ Acid reflux None so far, I have taken Prilosec for just under two years to keep my acid reflux in check as well as protect the lining of my esphagis from being deteriorated any more. Im not a good speller but that has nothing to do with prilosec. I Found no evidence of any of the side effects listed on this web site exept for some slight gas but i am also slightly lactose intolerant. recently I discontinued use if prilosec becuase of research that I have done about the side effects for prolonged use. My doctor also dismissed the two week warning label. I noticed increased digestion times(quicker food pass through) and a general feeling of lack of protection of my esophagous. Not to mention an increase in effects felt from acid reflux spouts. M 21 1 years
9/25/2008
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 4  "Acid Reflux" The only one that I could probably recall is tingling in arms. I ended up damaging the lower esophageal sphincter (LES) by eating foods that were too acidic without even thinking about it.Prilosec has helped tremendously after taking it for about five months.It takes time to completly heal the LES.Need to watch the diet! Symptoms like burping and fatigue could be from acid reflux itself. M 25 5 months
4/11/2009
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 4  GERD I tolerated the drug well for 14 days, then, following the instructions I stopped taking it and immediately had much worse acid reflux and nausea than before! So I have started taking the pills again. Why does the drug company limit consumption to 14 days? Are they just covering themselves legally? M 72 15 days
2/15/2009
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 4  Severe Acid Reflux Hard to attribute them directly to the medicine, but I am experiencing thirst and headaches (I don't have diabetes as far as I know) For me, this medicine is highly effective but the side effects may not be worth it. I can keep my acid reflux in check with dietary measures, so that's probably the smarter way to go. M 47 3 years
1/23/2009
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 4  Silent Reflux Funny feeling after eating. No problems whatsoever. I expect that with the reduction in acid production, some foods will be less likely to fully digest, thus encouraging weight LOSS. There is absolutely no reason why anyone should GAIN weight while taking this medication - it has no effect on metabolism. M 50 4 weeks
3/12/2008

 4  heartburn I had really bad heartburn before I started to take Prilosec. I took at least 2-4 Tumbs a day to get rid of it. At night I woke up several times because of heartburn. I started taking Prilosec and the heartburn was gone in about 2 days. However I experienced very bad headaches during the treatment (3times in two weeks) which I never ever had before. The headache usually hit me in the middle of the night and wouldnīt go away even after taking two Ibuprofen (200mg each). Additionally my upper back and shoulders hurt really bad too, so I couldnīt lay down anymore. So I spend about half the night sleeping in a sitting position with a really bad headache. The headaches did not come back after the 14-day treatments but the heartburns are gone. M 32 14 days
2/23/2008

 4  Acid Reflux Some severe knuckle/toe joint swelling and pain. Not constant and random. Leg aches. Constant and sometimes crippling muscle pain in the lower right back. Sleep problems. Constant minor headache. I've been taking this for almost 2 years on doctors orders. I asked about the max 14 days and he said not a problem. Any food at any time, especially but not limited to chicken, rice, french fries can close my throat down without warning. That means no swallowing even water or no burping to relieve pressure. I've had my throat expanded twice with good results the second time. Tried Protonix before and after the first procedure but it didn't work well enough resulting in quickly returning problems and a second procedure a year later. Without Prilosec daily (I skip days to test it) the acid reflux problem returns immediately. The throat is scarring regardless. Another procedure will have to be done but this stuff is buying me time. Not liking taking them though. M 56 2 years
2/24/2008

 4  heartburn gas it says right on the package not to take it for more than 2 weeks... im not sure why any of you consumed this product for such an elongated period of time... maybe this is why your side effects were much more serious than mine M 20 8 days
1/4/2008

 4  Acid reflux, Gurd Bad Bloating, vision problems, aches and pains,soft stool, light headed, Water weight gain. I went off the Medicine and all these symptoms went back to normal but the acid reflux was so bad I had to go back on it. It works for the acid but I hate the side effects. I've also been on Nexium, Prevacid,Acephex, Zantag, Pepcid Ac, Tums M 52 8 years
1/26/2008

 4  acid reflux Severe dry mouth, especially in the morning accompanied by severe headaches and nausea. Weight gain, and weakness in legs and arms. Sometimes would get a tingling in my left arm, and a metallic taste in mouth. Chest pains every so often. Cured my Acid Reflux. Weight gain may be due to the fact that since I have no acid reflux, I can eat more. I thought something bad was wrong with me with the dry mouth and headaches, and my doctor sent me to a sleep study suggesting sleep apnea, but none was found. I finally put 2 and 2 together and pinpointed it to PRILOSEC. I will be looking for another med. M 36 10 months
11/24/2007
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 4  stomach ulcer I had similar issues, however joint pain was present before taking Prilosec. I have read that stomach problems can cause joint pain, especially in the heels. Still having joint pain but not as severe. However 3 weeks after taking the 14 day regimen, the stomach pain is beginning to return. The package directions state not to take it again for 4 months. Has anyone tried taking Prilosec sooner than the 4 months? If so, what side effects, if any, did you experience? M 51 14 days
8/25/2007
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 4  acid reflux and indigestion Tiredness, weakness, sleeplesness, muscle ache, dizziness, i dont know if these side effects are due to prilosec but i noticed these side effects after i started prilosec. Well it does help my indigestion and acid reflux M 22 3 months
4/4/2007

 4  Acid Reflux Consistent gas, some dryness in mouth. The gas is nasty as hell and I figure it has to do with Prilosec. I have to take it daily or my GERD returns with added punch and pain. My stool is not very solid either. M 39 3 months
3/29/2007

 4  Dr. prescribed. I seem to itch all over at times, and then it goes away for a while. I will take Prilosec every other day to hopefully stop my itching. Any other ideas would be appreciated from others that had/have this problem. M 52 40 days
4/21/2005
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 4  GERD Occasional hives, burning sensation and muscle pain in armpits and upper arm; mild abdominal discomfort; joint pain, especially at shoulders, wrists, and behind knees. Prilosec certainly relieved the burning from my GERD problems but the added side effects make me worry that I have some sort of severe problem as yet undiagnosed. M 34 4 weeks
4/19/2007

 4  ulcer Flu-like symptoms. Ulcer pain stopped within hours. Then same night developed severe head cold, severe coughing incidents. Coughing woke me every 1-1.5 hrs. Extremely fatigued after days/nights of taking only short naps, then waking with severe coughing episodes. Coincidence? or Side effects of P? Not going to take the P this afternoon. I gotta get some decent sleep. Let me know if anyone else has had this experience. Send me email. My numerical rating of "4" is because it did stop the ulcer pain, or maybe the Chimichanga I ate at the same time stopped it. No kidding! M 64 5 days
5/6/2007
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 4  gerd M
5/15/2007

 4  too much ACID stomach pain, gas, very loose BM for weeks, sore throat?, redness in face, anxiety it completely cured my heartburn M 42 2 months
5/14/2007
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 4  Acid Reflux Disease Hair Loss. Unfortunately, I'm a lifer. symptonms return when I stop taking my medicine M 37 4 years
12/13/2001

 4  acid reflux and severe stomach pain Headaches and musculoskeletal pain ... especially within the shoulders Very effective for controlling the pain which was disabling in nature M 22 months
12/21/2001
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 4  Acid Reflux at end of day Muscle pain in the neck, arms and upper legs. Loose stools (not to the point of diarrhea, but close at times) and flatulence. My doctor initially had me on samples of Protonix, which worked great, but when I filled my own prescription, the $105 for a 30 day supply seemed pretty excessive, so he switched me to Prilosec OTC as an alternative. Prilosec is working great for the reflux problem, but my neck, arms and upper legs have been very sore since I started using the drug. M 40 14 days
2/11/2005

 4  acid reflux burning tender irratable bowels with occasional bleeding acid reflux is gone except it feels like it left my throat and went to my rear M 43 2 years
11/22/2004

 4  GERD Because my insurance company would not pay for Nexium I switched to Omeprazole. Within the first week of taking the drug I had two horrific nightmares that literally made me awaken to stop their continuance. The drug is working fine otherwise and I hope this side effect is only a brief conditioning until my body acclimates to the new drug. If the nighjtmares persist I will have to consider asking my physician for another medication. M 58 4 days
4/5/2007

 4  Acid Reflux Weight gain (75lbs) Low blood platelets, which resulted in severe nosebleeds. High blood pressure. Numbness in right side of my leg (syatica) probably caused by the weight gain. My doctor has diagnosed me prediabetic. Could Prilosec be contributing to this? Will Actos interact? My doctor doesn't think so. I'm not so sure. Is there any research on this? Any info is appreciated. Please email. Over all I am thankful for the drug,,, so far.. UPDATE UPDATE UPDATE UPDATE UPDATE UPDATE. The low blood platelets have become serious. 200 is normal. I had 15. Scary! There is some research to suggest the Prilosec may cause this. I was referred to a hematologist who had me stop taking the Prilosec. Within 2 months my platelets are up to 90 and rising. I have no doubt this was caused by the Prilosec. The only other medication I am taking is Actos. I am now using Pepcid for the acid reflux. Nowhere near as effective. So back to using antacid tabs for those flare ups. Oh, and I seem to be stuck with the extra wieght. DAMN! M 48 3 years
7/15/2006
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 4  acid reflex Sudden weight gain of about 6-7lbs after taking it for two weeks It apperas to stop the acid reflex M 55 2 weeks
1/22/2007

 4  stomach acid Muscle weakness esp. in my shoulders. They feel tired and weak. It helped my heartburn alot. Also, I have some lower bowel gas. None M 59 5 weeks
4/27/2006

 4  reflux diarhea Took my stomach pains away. Diarhea is mild, so all in all, it's helped me. M 16 1 months
10/27/2005

 4  Reflux, Scarring Minor level bowel pressure almost constantly. Irregular and frequent loose bowel movements. Never seem to evacuate completely. Can't tell at times whether I need to pass gas or actually move bowels. Worry about having an inopportune accident. Works very well treating the symtoms. Took two days off and reflux returned. Going back on. Side effects are bothersome, especially the feeling that I gotta go all the time, and not being able to tell the difference between the need to pass gas and move bowels. This is the only side effect I've had. M 48 40 days
10/12/2005

 4  diagnosed with acid reflux Have had spastic colon all my life. Finally got it under control this past year and then I was diagnosed with acid reflux. I am now experiencing constipation again and wonder if Prilosec is the cause. I googled the web for side effects of Prilosec because I finally got chronic constipation under control after many years of experimenting with how to get rid of it. The constipation came back at approximately the same time I started taking Prilosec. I don't know if the Prilosec is causing the constipation, but I can't go off it long enough to find out. The Priolosec has gotten rid of about 99% of the chest pain I was experiencing. (Pain was so bad, I went to the ER because I thought I was having a heart attack.) Going one day without taking it and the pain comes back. A previous contributor mentioned natural remedies for acid reflux and said that Vit. A promotes healing of the stomach lining. For the last 15 years or so, I have taken Vit. A for antioxident properties but only recently stopped because some "expert" said taking it on a regular basis wasn't good for you. Since my first bout with acid reflux was not too long after I quit taking Vit. A, I am wondering if M 51 40 days
9/10/2006
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 4  acid reflux excess weight gain 5-10lbs. decrease in regular bowel movments, if medicationis missed, acid returns instantly. works great stops acid production M 45 60 days
10/29/2006

 4  GERD Cleared up the acid reflux nicely but experienced some side effects. Mild feeling of weakness in arms. Persistent but mild pains and tingling sensation in arms and legs. More pronounced and persistent neck and shoulder pain with slight headache. Was taking Protonix Rx with no side-effects but switched to Prilosec OTC at doctors recommendation for cost savings. Probably going to switch back. M 35 24 days
8/15/2006

 4  acid reflux Possible weight gain over last yr close to 20-30 lbs! But not sure if its from Prilosec or just getting older and lazier! Best OTC on the market. Had heartburn all the time b4 prilosec. COuldnt sleep or enjoy evnings out. Prilosec helped me! M 30 9 months
1/2/2006

 4  Acid reflux and halitosis Mild to moderate headaches at first, then they decreased in intensity. Found that exercising when the headaches come on makes them go away! I'm taking the OTC 20 mg, thought that the 40 mg prescription would give severe side effects like the 150 mg Zantac did and the prescription Protonix. Have tried Zantac 150mg and 75 mg, Protonix 40 mg. The Zantac 75 mg helped alot and also gave me energy, but the headaches wouldn't go away, but they might have if I would have exercised when they came on, Zantac 75 also made me dizzy.. I couldn't believe the low price of the generic Zantac at Costco, it's less than 3 cents a tablet. Prilosec is about 60 cents a tablet at Costco. M 59 11 days
11/6/2005
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 4  constant GERD Occasional rectal bleeding and weight gain Would like to try and moderate the side effects and keep the benefits M 52 1 years
1/29/2006

 4  acid reflux headache,muscle pain, chest pain, back pain been taking proton pump inhibitors for 6 years but lattely noticed all simptomes above. had some in past but never connected dots. nexium and prevacid worked as good as prilosec but without side effect. this medication should be taken of otc market and added side effects on package M 32 7 years
10/11/2006

 4  Acid Reflux None directly attributable to Prilosec If I miss my Prilosec for more than 2 or 3 days (like forgetting to refill perscription :) the acid reflux returns with a vengance - and will take a couple of days to go away after restarting Prilosec. M 39 11 years
9/21/2005


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Average rating for drug: 2.3. This page is printer-friendly; use landscape print with background color turned on.
Key to ratings:
5-Very Satisfied: this medicine cured me or helped me a great deal.
4-Satisfied: this medicine helped.
3-Somewhat Satisfied: this medicine helped somewhat.
2-Not Satisfied: this medicine did not work to my satisfaction.
1-Dissatisfied: I would not recommend taking this medicine.

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