PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  GERD General side effects include many of the things listed here (joint pain, fatigue, stomach discomfort and sharp pains (probably from intestinal gas), lower back pain, etc.). However, much more severe side effects include a very bad case of clostridium difficile (C.Diff infection) a couple of years ago, and B-12 deficiency. The C. Diff went untreated due to me being such an unlikely candidate for contracting it. The B-12 deficiency has shown up in the form fatigue, back pain, minor vision problems, and is possibly even playing a role in fertility problems. After failure to conceive after trying for 18 months, I tested low for count (~11 million/mL, when it should be >>20 million/mL) and motility was below average. B-12 is essential to development of healthy sperm and sperm count. It is also essential in the production of DNA and cell reproduction functions. If stomach acid is insufficient, B-12 cannot be absorbed from food. There are also proton pumps present in the male re Prilosec was a miracle drug for me for some time. Specialists told me that I would likely have to take Prilosec (or similar) for the rest of my life. They said it was one of the safest and most effective drugs on the market and it was okay to disregard the warning labels. I believe that it is effective, and safe in the short term, but long term users beware. There are many reasons that your stomach produces acid (proper nutrient digestion/absorption, immuno-defence). Stopping acid production for short periods may be effective to allow esophagal healing, but long term use may be risky. I stopped taking Prilosec 3 months ago. I have controlled stomach acid problems through diet (mainly low sugar) and occasional Tums. I no longer have stomach pain, lower back and joint pain has diminished. I have been supplementing B-12 intake (1000mcgs/day methyl-cobalmin w/ B-6 and folate) for less than one month, but already notice I am feeling more energy and mood improvements. It is yet to be M 32 5 years
4/7/2008
 1  GERD Bloating, gas, nausea/stomach cramps after meals, constipation, depression, back pain, confusion, clumsiness, fatigue Have only been taking omeprazole (generic) for about 10 days. Started noticing all my symptoms about 5 days ago, but was on antibiotics and attributed it to that. Antibiotics are gone and still having almost unbearable stomach and abdominal cramps after eating. It almost never goes away. I didn't think it was the antibiotics anyway because I've taken this one several times before and never had a problem. Emetrol is about the only thing that will even make a dent. Going to stop the omeprazole and see what happens. I'm just so glad I found this info here. The insert with the med does not even name any side effects!! F 44 10 days
4/8/2008
 1  Heart Burn The drug helped my heart burn, but I believe my optic nerve tremor is being caused by it. I have never had this before, but did not think the agitation and flutter of my eyelid was a result of the medicine. However, the more I read, the more I am convinced it is being caused by it. The flutter started on about the 8th day. I have stopped the medicine on the 12th day of 14 day dosage. Please someone let me know if the eyelid nerve flutter will stop. Please, use diet, not this drug, to help stop your heartburn or acid reflux. This drug is dangerous! M 47 12 days
4/8/2008
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 5  Acid reflux, heart burn None, This produced the best results of any medication I ever tried. M 63 8 years
4/10/2008
 1  acid reflux I took 40mg nexium for two years. I decided to try prilosec otc because I didn't need a prescription. After taking the prilosec for 4 days, I developed a severe dry persistant cough. After 48 hours of not taking prilosec, I'm still experiencing a severe cough. F 45 4 days
4/10/2008
 1  side effects blood pressure meds gas,explosive diarrhea,and horrible chest pains Had quad heart bypass in Dec.'07.Taking this to ward off side effects from blood pressure meds. It feels like my chest has been cut open a second time. Will never use this product again. M 58 4 days
4/11/2008
 3  heartburn Extreme fatigue, dizziness, stomach cramps, back pain It helped the heartburn go away, but not worth the side effects......I'd rather have heartburn than be so tired all the time. F 34 11 days
4/12/2008
 1  GERD/acid reflux Some relief from acid reflux symptoms, but had diarrhea almost on a daily basis, daily stomach pain which kept me feeling like I needed to eat all the time, and worst of all--decreased bone density (discovered later, due to incomplete absorption of minerals), condition known as osteopenia (precursor to osteoporosis). Am now 61, but started this drug around age 52. Had suffered with GERD for at least 20 years, but symptoms got worse with age and increasing weight. Went off Nexium, then to Prevacid, and later to Prilosec, hoping to get fewer side effects, but not successful at this at all. All together, was on proton-pump inhibitor (PPI) drugs for about 7 years. Gallbladder removed at age 44. Diagnosed with rare-type pancreas tumor in 2005 and had surgery in Dec. 2005. Went off all PPI drugs in early 2006. Real reasons for GERD: eating too much sugar and wheat (and other gluten grains) for many years, and not enough bile acids for proper digestion. MY CURE: taking bile acid salts and full-strength pancreatic enzymes supplements with every meal. Drastically changed my diet to high-fat, moderate-protein, low-carb (NO wheat or other gluten grains) with absolutely no processed food; added raw dairy and grassfed, pastured, locally-grown beef, poultry, pork, organic produce. I have normal digestion now--no F 61 4 years
4/13/2008
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 5  GERD and stomach pain None. Prilosec worked great for me immediately after first taking it. Eventually I took it every other day, to cut down on the expense, and it still worked well, then I finally stopped it altogether. I was okay for awhile, but gradually, over several months, my stomach problems increased tremendously.....the bloating was terrible, especially after eating, and I had bad pains.....so I went back to one Prilosec per day. After about three days, I felt great and now my stomach problems are all a thing of the past. I can't get along without this medication and have decided that hang the expense, it's worth it! F 57 2 weeks
4/14/2008
 1  GERD shortness of breath, anxiety, hazy during the day, insomnia, diahrea, vomiting, tighness in chest, weakness, listlessness, i was diagnosed with GERD after what i thought was a heart attack and lo and behold, prilosec was the weapon of choice to combat this ailment. after the first day of dosage i noticed no real problems but i felt slightly short of breath. but after day two the insanity kicked off one by one, with the vomiting and diahrea coming to the plate followed by insomnia and anxiety. then the chest tightness and the feeling of being stabbed in the chest while lying down, sitting up or anything. i haven't been able to hold down more than a small sandwich since day two of this treatment, and that is stretching it. and also my toal sleep is around 7 hours for three days. for what you have to put up with to treat GERD, heartburn, or acid reflux, i don't recommend this product at all. i would gladly rather pop tums all day than feel like i am dying and going crazy at the same time. M 23 8 days
4/15/2008
 3  Stomach Ulcer Chest Pain, Depression, Irritability, Nervousness, Anxiety, Brain Fog, Bloating, Swelling (especially left leg), Itching Itching Itching Skin In October '07 I was diagnosed with a stomach ulcer (H-Pylori present) and was quite sick. The doctor prescribed antibiotics and antacids. All the antacids caused extreme gastric distress, and then I tried Prilosec OTC. I got immediate, miraculous relief from the stomach acid/ pain. I was elated. Unfortunately, I started having chest pain, depression and anxiety, so I cut back on the Prilosec, taking it about 3 days on/ 4 days off. The chest pain went away but I started getting bloating that seemed like extreme water retention, worse in my left leg. Five months later, I am still having swelling problems and the anxiety is worse. Prilosec is the only medication I take, and it is not normal for me to have depression and this much worrisome/ nervousness. Sex drive also disappeared. So I'm going to go off this for a week and see if something gets back to normal. F 47 5 months
4/18/2008
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 3  Acid Reflux Nothing until a few weeks ago, lump in throat, tingling in fingers, neck muscle pain, eye lid twitch, metallic taste, burning tounge, foggyness. Took prilosec 20mg otc for 5 years. Nothing bad happened until a week ago when it felt like a lump was in my throat. My ENT and I thought it was a GERD symptom and keep truckin on with Prilosec. Days later I started having tingling in my fingers and bad neck pain. I thought it was my TMJ and my peripheral neuropathy. Then days after that I noticed a strong metallic taste and burning tounge sensation. I took two 20mg otc and it made me feel very foggy, forgetfull, and the tingling and lump in throat feeling became worse. Read that after a while your body builds up an immunity and causes toxic results. I was having toxic results as one from prilosec is more reflux! After 2 days of no prilosec, lump in throat 90% gone, tingling gone, foggyness gone, neck pain gone, no burning tounge sensation, small metallic taste, upper eye lid twitch comes and goes. Prilosec worked great for me for 5 years, I had built up tolorance and now I am looking for a new helper. F 21 5 years
4/19/2008
 1  too much acid chest pains that spread to my back,neck, arms, shoulder blades and just ached all over. shortness of breath and severe depression. went the er and had 2 ekg's ,blood work and a cat scan,dr. said my heart was fine but there is a mass around my kidney. i told him i thought these pains may be from prilosec and he didn't agree. quit the medicane 3 days ago and still have the pains F 43 11 days
4/22/2008
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 1  acid reflux very bad bloating,dry mouth,cough,neck pain,dizzyness,out fo focuse,abdomine pain like stabbing,head aches,anxiety,depression,lack of energy,tired feeling all day,tingle in hands,back pain,itchyness,eye twitch I was never aware of the side effects before taking this medicine.It was recomended by my doctor to take this for acid reflux,i could not figure out what was wrong with me there was days i couldnt hardly function.DO NOT TAKE THIS PRODUCT IT IS THE WORSE THING I EVER DID!I'm just worried to see how long these horrible side effects last this is day one of me not taking this horrible product.I can't beleive they don't give more warning,im shocked and discusted.All side effects seem to hit slow snd then all at once.ONCE AGAIN STAY AWAY!!!!!!! M 29 6 months
4/24/2008
 1  Omeprazol Eye Twitch! Extreme fatigue, leg cramps, anxiety. Slight anxiety and weight gain. I have switched to using papaya enzyme, to aid in digestion, and a calcium supplement in the morning and it seems to be helping quite a bit. I have also been eating more vinegar and that seems to work. F 38 11 months
5/2/2008
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 3   M 18
5/5/2008
 2  gastritis/esophagitis/GERD trip to ER for severe trembling/near seizure, heart palpitations, almost impossible to breathe, urination 4 times per hour, severe dizziness and confusion, near fainting like curtain being pulled over eyes, blurred vision, arches of feet cramping severely, occasional stabbing pains in different parts of chest, chills, insomnia, nightmares and a general feeling of malaise as though I were going nuts and withering away. For 6 months I had a pain and swelling located dead center of my lower chest, directly beneath the sternum. It was a gnawing pain, but not severe. I thought it was a hernia or pulled muscle, so I just ignored it for a few months. Doc guessed it was a stomach disorder and put me on Omeprazole 20 mg daily. Endoscopy showed gastritis and H. Pylori present. That's when the nightmare began. I think I would rather have gastric cancer than deal with what's been happening the last 5 weeks. Been having hallucinations as though I drink Peyote daily, every symptom of a terminal panic attack to the point where I had to see a shrink to rule it out, hot flashes sometimes, chills sometimes, scariest was the near-fainting feeling and breathing trouble, like I'm on the brink of just passing out. Also, heart rhythm changes, blurred vision, ringing in ears, head pressure, and a generalized feeling like you're are going insane, or losing complete control of your body and mind. Cognition suffers, as well a M 38 6 weeks
5/10/2008
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 3  GERD Mild Headache, occasional nausea/vomiting, occasional light-headedness. Was on Nexium for 7 years. In 6th year I began having fatigue and dizzyness during exercise. Went to ER with atrial fibrillation - they zapped my heart back to normal beat. Tests showed my heart was healthy. Cardiologist said Nexium should have nothing to do with this episode, but I later found out that long-term use can deplete B12 and iron. 2 weeks after starting b12 and iron supplements, I felt much better. Atrial fib has not returned. I concluded my heart was having to work too hard since blood could not carry oxygen properly. Doctors need to warn people about the vitamin issues. Headaches and nausea started when I switched to daily Prilosec OTC, but since it is much cheaper than Nexium, I think I will stick with it, as the side effects are tolerable compared to the GERD. M 50 3 months
5/21/2008
 2  Acid reflux Definitely cramping in the chest, feels like a heart attack. Pain in lower sternum. Stomach aches whenever I cough. Not to mention severe anxiety, suicidal thoughts, extreme depression, and just being in a foggy haze. I made it to day 4 and I'm already throwing the box away. It pisses me off that doctors are forced to push this crap into patients faces cause some big Drug Company is telling them to do so to cash in on the big $$. And how does this make a doctor different than a dealer..? I am quite the socialite (i like to live life). I have been out every night of the week for the past two years. Last nite was the first time I stayed in cause I felt so crappy, physically and mentally, and its do to this satanic pill! M 26 4 times
5/21/2008
 1  vocal cord surgery/reflux Upset stomach, worst heartburn ever, fatigue, diziness, headache, nausea, diahhrea, lump in throat I started taking this 2 weeks ago after being diagnosed with vocal cord polyps. After surgery for polyps, my doctor has had me taking it 2x a day. He recommended this medicine as an alternative to Nexium since my insurance doesn't cover it. All week I've been tired and sick to my stomach. In addition I've got the worst heartburn I've ever had. I would not recommend this product, I only hope it hasn't hindered my recovery from surgery and caused further damage to my vocal cords. F 37 2 weeks
5/26/2008

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