PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  GERD These effects happened upon withdrawal of this medication: severe anxiety and panic attacks, heart palpitations and prolonged qt interval on ecg, tremors, muscle pain, stiffness, severe twitching, insomnia, nausea/vomiting, headaches, neurological problems, brain fog, memory loss, and more. Symptoms persisted for weeks. These issues result from immune activation when you stop taking the medicine also calcium and magnesium imbalances. I am writing this on behalf of my husband. The only things that helped him were the following: taking chewable calcium, taking a magnesium supplement and tapering off over several months. He had to get a prescription for a 10mg pill from his doctor in order to do this. The calcium was really helpful and the chewable form seems to be more bioavailable and helped with the tremors. Your body can quickly become dependent on this so be careful taking this, that’s why it is only recommended for short term use (2 weeks and under) but most doctors believe it is a harmless pill. Just like others on here, none of the doctors acknowledged my husbands symptoms as being a result of coming off this medication, they all thought we were crazy even though there are articles stating that these drugs effect the muscles, brain and immune system and cause serious withdrawal effects. M 36 1 years
40
4/9/2019
Email
 1  Acid reflux Extreme anxiety terrible gas and bloating back pain. chest pain. This stuff is awful. I have been off it about a week now and still feel so much anxiety I have to take something to calm down. I read that hcl+betain will help restore digestive health. I feel that Prilosec destroys gut health which affects mental and physical state. I have ordered hcl+betain and plan to try this. Please do not take this drug. F 65 30 days
40mg
4/4/2019
Email
 1  Possible stomach ulcer After 4th day of being on this med, I started having blurry vision, night sweats, fatigue, body aches, heartburn, and anxiety. After a week off from the meds I am still having these side effects. It has been difficult going to work because I so tired. How long can these side effects last? Please email me. Thanks! F 35 10 days
20xD
4/2/2019
Email
 5  GERD...Acid Reflux Have had no side effects from this drug. It has worked great for me. Controls acid and keeps it away. M 51 20 years
20mg
4/1/2019
Email
 1  Heartburn Severe stress and anxiety, confusion, crying over everything, headache, stomach pain, racing heart, fatigue, sweating. HORRIBLE!! It got rid of heartburn but the side effects were bad. On the 3rd day I started stressing really bad over everything and having severe anxiety as well. Heart would race and pound and crying wouldn't stop. Almost ended up going to the er when I decided to not take prilosec anymore. I started feeling better after 2 days but not feeling 100%. Anxiety attacks are still happening. F 40 7 days
20mg
3/26/2019
Email
 1  Chronic Heartburn Anxiety, heart palps, panic attacks, disassociation. This is to update from my review 2/26/19. Panic attacks have lessened but are still present. Heart palps are not as frequent, but still a nuisance. I ended up at the er anyway - $1500 later I was diagnosed with PVC's. I'm still hoping this is not permanent and that I can get on with my life soon. F 38 3 months
20
3/7/2019
Email
 1  GERD Spaced put feeling, muscle twitching, insomnia, rapid heart rate, abdominal pain, back pain, high anxiety I had a single bout of acid reflux. I was prescribed these pills and they worked for the 1st month. Started having upper abdominal pain along with some back pain between my shoulder blades. I had an esophageal barium x-ray, abdominal ultrasound, endoscopy and colonoscopy. All came back clean but still felt like something was wrong. Anxiety was on 100 which exacerbated my stomach pains. Decided to go cold turkey 4 days ago. Anxiety has come down a bit and my body is starting to feel better. We'll see in the next few weeks! M 47 3 months
20mg
3/6/2019
Email
 1  Acid reflux Extreme chest tightness and burn, zapping electrical type pain in arms and under ribcage, severe panic attacks, agitation, dizzy and brain fog Why is this stuff being prescribed is what I want to know! I ended up in the ER thinking I was having a heart attack!! F 55 3 days
20 mg
3/5/2019
 1  Chronic Heartburn Anxiety, tachycardia, chest tightness, confusion, adrenaline, heart palpitations, panic attacks. I was on the rx form many years ago for an ulcer and I never noticed any side effects. I picked up the otc for returning symptoms, for some reason the otc is NOT the same as the rx! After 2 months I began developing the above side effects. Its been 6 days since I discontinued and I am STILL having debilitating panic attacks! I am very close to going to the er, but after reading these reviews I know it will be a waste of money....i will just have to suffer, but who knows for how long? And DUH the package says do not use for more than 14 days but all my drs said it was fine to use beyond that. F 38 3 months
20 mg
2/26/2019
Email
 1  Gerds Bad side effects. Sick at stomach. hair loss. pain in stomach. Teeth hurt. Back hurts. Lots of serious gas. Can't sleep. Burning in throat. Feel depressed. Cant eat much. Chest hurts. I take no other meds. Crying withth pain. Restless. Legs. Don't take it. Can't get off or it's worse. Hate this drug. F 63 10 days
20 mg
2/26/2019
Email
 5  Lpr No side effects F 54 4 months
20mg 2 a d
1/17/2019
 1  LPR, stomach bleed from endoscopy Brain fog, irritability, easily stressed, depression, increased anxiety, muscle aches, numb limbs, heart palpitations, join paint especially in right shoulder and arm, wrist pain, memory and attention issues.. probably more. ***update*** This drug treats the symptoms of acid reflux. This should not be used long term. Find out the underlying cause of your issues! If you must take it long term make sure you're in the care of a good doc that will test your vitamin levels regularly.. B12, iron, magnesium, D etc. This drug will likely cause more harm than good even if it isn't immediately. I am still suffering with minor improvements after 4 weeks off the drug. M 27 5 months
40mg 1x da
12/12/2018
 1  LPR, Mild Acid Reflux and Dysphagia Severe anxiety, panic attacks, dizzy spells, brain fog, blurred vision, fatigue, feeling faint, nausea, stomach cramps, sharp pain radiating from chest to back shoulders, dysphagia, feeling of doom and hopelessness Do NOT take this drug or any sort of PPI. Please email me if you know of a way to get this drug completely out of your system, and return to a normal life. I'm desperate. F 24 50 days
40mg
12/5/2018
Email
 1  Ulcer, Gastritis Panic attacks, adrenaline rushes, heart palpitations, light headed, breathless (inability to take deep breaths), pain in abdomen (tightening, cramping) and soreness in ribs, pain twinges and pressure in chest, hot flashes. I am still not off this med. My doc insists what I am experiencing are not side effects yet all these symptoms started 4 days after taking prilosec. I am still trying to figure out how I can get off this drug before it kills me. What do I replace it with? F 47 12 days
20 mg 2X day
12/2/2018
 1  Gerd Brain fog, extreme anxiety, right chest, shoulder, back and under arm pain.. can't tell if it's from tension or just pain, hard to describe, bloating, indigestion, weight gain, magnesium deficiency I quit Prilosec the first time without having any natural tools to combat the rebound (which my doctor did not warn me about when his prescription ended) had severe reflux and esophageal spasms. This drug is a nightmare, cure GERD by increasing stomach acid not lowering it. This drug makes things worse for your gut and leaves you malnourished! M 27 5 months
40mg 1x
11/14/2018
Email
 2  GERD M 45 100 days
40 MG 1X day
8/21/2018
Email

Patient History
 2  Heart Burn Palpitations, upset stomach/nausea, chest pain, chest tightness, a bit short of breath, fatigue I thought I was crazy, like a lot of other people on this medication. I'd only been on it for 3 days before I felt the symptoms. I was sitting, eating breakfast and right as it kicked in I suddenly felt my chest was tight, harder to breath. It didn't go away the entire day which was unusual, not like the mild chest ache from heart burn. I was scared of course! I thought I was having a heart attack or something was just really really off. A lot of other people say this medication spiked their anxiety; I'm not sure if the omeprazole gave me anxiety or just the symptoms made me more panicky. The frustrating thing is the more I worried, the more the possibility that I was making it worse. I was so relieved to find other people commenting on this medication, I teared up. So even people only on it for a short time also feel like death is behind them! I didn't want to eat, I could barely do basic things I was so tired, and of course I was scared out of my mind that I was dying. It's only been one day I'm off of it, and the palpitations started up. I wish I didn't have to think about them, that's why I'm writing this to give help to someone who may need it. I think that if you've found other medications to make you sleepy or give you brain-fog, or basically mess with your head, this one may too. Besides that PPI drugs don't even fix heartburn necessarily, they just block the acid but the moment you're off the medication, the floodgates open and in come all the acid. F 18 5 days
20 mg 1X day
7/17/2018
 1  Minor Gastritis heartburn Headache, Brain fog, unpredictable bowel habits, anxiety, panic attacks, out of body feeling, weird sensations in extremities, mood swings This drug is terrible. I was a normal healthy person until I started having severe stomach issues. I went to my GP and he prescribed me Prilosec 20mg twice a day. I started taking this and immediately got a headache which I thought might have been caused by another medication they prescribed me at the same time. Long story short my gallbladder was the problem. I had it removed but was told to continue with the prilosec. STUPID. I have since stopped the drug and I am getting better. SLOWLY, 2 steps forward and 3 steps back it feels like. I am taking b12, D3, and Magnesium. These have helped with the headaches and for the past week I have felt better. I stopped the prilosec about 3 or 4 weeks ago and still have some of the side effects. I really thought i was going crazy, never depressed, never anxious, and typically was in a good mood until i started this hell drug. I wasn't producing enough acid and they still kept me on a PPI?? you have to do your own research and cure yourself if you dont want to be pumped full of medication. Feel free to reach out to me and talk this was/is a horrible time in my life but I am seeing the light at the end of the tunnel. I am more than happy to talk to anyone about my experience. M 28 8 weeks
20 2X day
7/13/2018
Email
 1  Gastroenteritis I really regret taking prilosec, i fell ill with a virus last december that caused gastroenteritis (severe acid reflux and diarrhea).. i was told to take omeprazole for 14 day treatment.. at the time i did not experience any side effects so after the 14 day treatment was over, about a week later i experienced acid rebound that sent me to the ER. The er dr said i needed to up the dose to 40 mg 2x/day... and this is when i became more ill.. i had severe diarrhea for 9 days, blurry vision, brain fog, muscle twitching, cramping, body jolts before going to sleep, . i couldnt digest my food.. but i did not know what was happening to me.. i was so sick i had to have a colonoscopy and egd.. i was told i had unspecified colitis.. i stupidly cont this drug bc thats what the drs told me to do.. and as im trying to heal my gut from whatever virus i had i started to develop new symptoms.. extreme brain fog, memory loss, fatigue, anxiety, muscle twitching, buzzing in certain parts of my body.. frequent urination in am. I feel as if i have nerve damage of some kind because of this ppi.. after 4 1/2 months of this posion i have since stopped this med and it has been 11 days but my twitching is still there.. i know this drug caused these other problems bc as i weaned from 40 mg to 20mg to then every other day i began experiencing body jolts and more nerve problems, numbness in certain parts, etc. has this happened to anyone else and did anyone make a full recovery?? I need some help please.. Awful, do not take this drug. F 33 5 months
40mg
6/21/2018
 1  Suspected gastritis Severe anxiety, unexplained deep muscle pain, and general feeling of not being well. Stopped taking this crap 2 months ago, and anxiety has lessened but muscle pain in my thigh persists. Some days better than others, hope I can return to my old self soon. M 59 30 days
20MG 1X day
4/30/2018

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