PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  bile, acid reflux I experienced dizziness all day on 1 pill a day along with stomach ache, trembling, nausea and vomiting, cloudiness in head, fatigue... I researched the ingredients and find it shocking that the FDA ALLOWS the consumption of such a combination of poisons by humans! The medical field in general ignores the importance of 1st testing for HPylori and eradicating it as it is a sinister bacteria. They simply mask it w/ dangerous poisons like PRILOSEC instead!! If you have Hpylori have your doctor prescribe OMECLAMOX for PRECISE eradication because even chemotherapy won't kill it, it simply cloaks itself and becomes stronger. 56 4 days
20mg
6/27/2015
 1  Barrett's I took Omeprazole/Prilosec at 40mg for almost 6 years. I stopped taking it in January of this year and have been supplementing with magnesium since. This has been terrible and the worst time of my life. Becoming ill crept up on me slowly and by December last year I thought I was in my last days on earth! My symptoms are: anxiety and depression, muscle weakness and fatigue, nausea, headache, vertigo/loss of balance, fuzzy confused feeling in my head, inability to focus and concentrate, dry eyes, terrible cramp in legs abdomen and even hands and fingers, heart palpitations, no appetite, no interest in the future (an inability to get excited about anything from vacations to birthdays). I could go on.......... I have experienced a gradual improvement since I stopped taking the drug, dramatic at first when nausea, headache, flatulence and general unwell feeling disappeared almost overnight. I had a further dramatic improvement when I started supplementing with magnesium in March and lost the extreme depression, anxiety and vertigo, again within a few days. I can now get mildly excited and look forward to things again and my appetite is coming back a little. However, muscle weakness/fatigue has continued to worsen and I am very concerned as I was previously very active and now can't run at all due to muscle weakness and muscle fatigue and I am now even struggling to walk. This drug should be taken off the market. M 54 6 years
40mg 1X day
6/27/2015
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Patient History
 1  GERD SEVERE ANXIETY, DEPRESSION, EXTREME FATIGUE, WEIGHT LOSS, DIARRHEA NEVER TAKING THIS AGAIN!! STARTED WELL BUT WENT FROM HAVING ACID REFLUX TO DEPRESSION WHICH LASTED WEEKS. M 34 14 days
20MG 1X day
6/11/2015
 1  barratts oesophagus Heart palpitations.generally feeling unwell.clearing thoat constantly. Joint pain in knees.thudding headaches.anxiety.depression.tingling in soles of feet. Muscle cramps.insomnia.high bp.osteoporosis liver problems.. list is endless!! Ive been taking omeprazole (prilosec) for 3 years for barratts and i have been fine,, no side effects and felt really well..then in jan this year i started feeling very down and generally unwell,the soles of my feet started tingling and pain/ cramps started shooting up my legs,my knees started aching.i went to the docs and had blood tests done and scans arranged.the scans showed osteoporosis..the bloods showed liver functions abnormal..this is still ongoing and being investigated. Im now getting foggy headaches ( never suffered with bad headaches before) and feeling very down. This pins and needles in my legs is constant and driving me mad! Nobody has suggested that omeprazole could be the cause of my mounting problems.l found this website on sat 30th may when looking for side effects of omp....omg! I couldn't believe what I was reading!!!ive stopped taking this drug, and im trying to cope without it. Ive started taking magnisium calcium and b12 supplements as thats the commom suggestion on this site. Im hoping i can get though this,, im in agony.thanks to all previous users of this shit for reporting the repercussions! F 59 3 years
20mg
6/4/2015
 1  h. pylori ANXIETY, DIZZINESS, NAUSEA, INSOMNIA, spacey feeling, memory issues, OFF BALANCED feeling, JITTERY sensation in body, muscle aches, joint pain, tingling and numbness in toes and fingers, loss of appetite, low blood sugar (I'm not diabetic) having to eat every 2-3 hours, LETHARGIC, blurred vision, eye pain, ringing ears, sore gum, weird fullness in my head, black stool, frequent urination, feeling like I'm about to pass out but I don't, back ache Took Pylera and Prilosec to eradicate h. pylori. Currently going through day 3 of horrible withdrawal which is many of the symptoms listed above. Waking up with anxiety, nausea, off balance feeling, dizziness, and jittery feeling. Having to take Ativan twice a day to take the edge of what I'm going through. The anxiety is constant, the jittery feeling is constant, the dizziness varies in intensity, off balance whenever I'm walking also varies in intensity. Taking vitamins, probiotics and eating plenty of yogurt and kefir to repair my system. Praying that the bacteria has been eradicated. There has to be a kinder, safer, better way to eradicate h. pylori without having patients suffer so much. I feel that my original digestive ailments were intensified by the medication side effects. How long before I begin to feel "normal" again? F 54 14 days
20 2X day
5/30/2015
 2  gerd, stomach and esophagus inflamm Joint pain, primarily in hips, knees, ankles. Burning sensation in legs, thighs, calves, shins. After just 3 days on omeprezole (twice a day), I noticed the feeling of inflammation in my legs when lying down to sleep. First I'd feel it in my left hamstring, then right shin, then ankle. It was a dull, burning sensation. Doctor said it was a rare side effect, and he switched me to zantac. The burning legs sensation went away that first night. No reflux symptoms, either. F 42 3 days
20 mg
5/20/2015
 1  Dysphagia and GERD Anxiety, depression, fatigue, insomnia, apathy, suicidal ideation etc. Started taking this as a young teenager and after 12 years decided it was time to stop because I had read omeprazole could cause osteoporosis if taken long term. Very quickly (within 2 days) after discontinuation a lot of what I had thought were mental health issues lessened considerably and I felt so much better emotionally apart from a few episodes of crying for no reason in the few weeks after stopping. I had seen psychiatrists for 10 years but could never get a decent diagnosis or work out any causes for my depression and so on. I am certain it was omeprazole contributing to my poor mental health especially as these side effects seem to have just crept up on me. I am now a little upset that if I had not taken this drug for so very long I might have done better at school and university which was always a struggle. But, anyway, I am so much happier without it and it is never too late to have stopped. However, I do recognise that there are medical circumstances where such a drug as omeprazole together with any side effects is definitely worth taking as it does stop stomach acid. The point is I wouldn't fear taking this drug for a short period if you need it, but don't be left on it for no reason like me. As for how I dealt with acid on withdrawal, I took Gaviscon Advance double action 6 times a day for 2 weeks. It worked great. M 26 12 years
20-40mg 1X day
5/19/2015
 1  H Pylori Where do I start: pain all over body, particularly joint pain, depressing thoughts, mild headaches, extreme fatigue, dizziness that would last pretty much the whole day. This drug has been hell on wheels for me. It had me believing that something serious was going wrong with me. I have been off it for about 3 weeks now & I feel so much better. I am back to my normal self again but the acid reflux is back, going to change my diet to see if that helps. I welcome any suggestions on controlling the acid. Best wishes to everyone suffering from this horrible drug. F 33 2 months
20 Mg
5/17/2015
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 5  GERD Dry mouth, headache. M 56 2 years
10
5/16/2015
 1  acid reflux Stomach pain, nausea, sun sensitivity, dizziness, depressed mood (including suicide ideation), lethargy, itchy skin, acid rebound on day 5 when tried to stop after two weeks use. Then reinstated after recognizing the rebound for one week and then decreased dose by half for one week and then stopped. Negative symptoms went away. On week two with no medication and feel better. F 13 4 weeks
20 mg 1X day
5/14/2015
 1  Acid reflux anxiety my god I can't list them too many. lets just say I have thought I would not be here to write this please contact if you have any ideas on getting this stuff out of my life feed up with the bed room as lovely as my wife is of 35 years marriage this is beginning to wear thin also contact for any reason some times knowing someone else going though same things helps M 55 10 years
20mg
5/11/2015
Email
 1  Bleeding ulcer Dry cough after starting Prilosec. Dr thought BP med caused it and chgd med 3 times. Didn't help. Now I have cough, nose and ear congestion, chest pain. Bowels move 8-10 times a day. Think I have acid burns on, well, you guess. Stopped Prilosec 2 days ago. Taking chewable antacids and watching what I eat till I can reach my Dr. Things WOULD get worse on a Fri night b F 60 4 months
20 mg bid
5/10/2015
 1  Acid Reflux Fatigue, muscle cramps, rash over 70% of my body, chills, frequent urge to urinate, dry mouth, dehydration. My doctor said it was OK to extend the dosage but I only took it for 2 months. I noticed fatigue when doing simple things like walking to my car or climbing stairs, then I got severe muscle cramps, particularly at night. This drug depletes magnesium which, I assume, caused the cramping. The piece de resistance was the rash. It began in my genitals and quickly spread to over 60% of my body which felt like it was on fire. The itching was similar to that of poison oak. After three conversations with advice nurses who just didn't get it and who prescribed ineffective meds I finally was seen by a doc. Now I'm on a steroid and other stuff and it's finally calming down. But I can't wear clothing without discomfort which is a bit of a problem. I have been off Prilosec for a about a week and feel so much better, even though the reflux has returned. I'll find another way to deal with it. Never again will I take PPI. F 67 2 months
30 mg 1X day
5/2/2015
 1  Acid Reflux Lethargic, hip pain. Took for 18 months before finding out that I DID NOT have acid reflux/GERD! Now I walk with a limp because of hip pain. All for NO reason! This is an evil drug. Hard to get off of and can cause permanent damage. Don't use it!! M 58 18 months
40 MG 2X day
5/1/2015
 5  GERD None except breakthrough heartburn Controls my GERD as well as Nexium at a lower price M 50 8 years
20
4/28/2015
Email
 2  GERD, Hiatal Hernia Insomnia, increased anxiety, malaise Took a small dose of this medication daily for years. Did not relate my insomnia, interrupted sleep, waking early and not being able to go back to sleep to this medication until I stopped it for few weeks. Went back on it and the above symptoms returned. Will have to find another alternative. F 60 6 years
1/2 of 20m 1X day
4/27/2015
 1  gastritis anxiety, dizziness, lethargy, blurred vision, nightmares, insomnia, dry mouth, , depression, dry eyes, dry throat, dry skin, migraines, agitation, vertigo, nausea, horrible brain fog, feeling very dehydrated. I had to stop today after only 4 pills. Each day it got progressively worse (the side effects). I feel much worse after starting this medication. If you google "wistar rats, anxiety, lansoprazole (yes I know this is omeprazole in Prilosec but I think any of these PPI's are similar), then you will come across a study that shows that lansoprazole (Prevacid) induced anxiety in the wistar rats by increasing the Substance P in their brains which is anxiogenic (increases anxiety). So it is not a stretch to think that if lansoprazole could do this rats, probably omeprazole has the same effect on Substance P and anxiety. Increase substance P also causes increased pain. Lovely drug, these PPIs. No more for me. I hope the side effects go away soon. F 4 days
20 1X day
4/27/2015
 1  reflux Headaches, nausea, neck And back pain, sadness, eye aches, mood swings, severe bloating, full feeling all the time, loss of appetite I kept feeling like I was coming down with the flu. I have aches all over. Severe bloating. My wife thought I was just being a hypochondriac. Saw doctors telling them I have never felt so bad in my life. They actually thought my sinus issues were the cause and they suggested more prilosec. I called my ENT and he told me of the side effects. I googled them and I literally have all of them. Even the spasms. I'd rather clear my throat than to deal with the mysery this drug has caused. Hope my gas and bloating subsides. I have never in my life had these feelings. Ever. M 36 1 months
20mg
4/21/2015
 5  Gerd I love it. Helps a great deal. F 45 1 years
20mg
4/20/2015
 2  Gastritis, acid reflux 30 mg capsules helped stomach problems in 2 days. However, end of week 2 my blood pressure rose sharply. Dropped to 20 mg, stomach fine, blood pressure rising after 10 days. I will drop all Prilosec. My pharmacist informed me that hypertension is a true side effect for some. I find that my 2 Drs "wave off" the possibilities of side effects from PPI's and other drugs. Find a great pharmacist. They are the drug experts. F 72 3 weeks
30 and 20
4/20/2015

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