PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  H Pylori / Gastritis Chest tightness, tender feeling in esophagus when swallowing, very sore neck and upper back, stabbing pain in upper back, rib cage or similar pain, tingling down left leg shin and foot, joint pain in wrists and ankles. Had stomach pains, doctor prescribed omeprazole without doing any tests. Took 1st dose and straight away felt weird sensation in chest, then neck stiffness and pain, back pain and joint pain. Depression. Didn't feel was right, eventually got 2nd opinion. Had endoscopy and tested positive for H Pylori. Antibiotics + PPI Omeprazole 7 days. On day 2 of course noticed very sore right side neck, first i thought this was due to indigestion and reaction to antibiotic (even though first time I ever took antibiotics no reaction like this), but then realised it could be omeprazole as had same pain first time I took it a few weeks back. Then, day 3 got progressively worse. Mid upper back pain, and joint ankle pain left side, depression and feeling so low and moody, creaky voice, sore and dry throat. Over the course of the next 3 days, I was almost bed bound with my laptop as just had no will to do anything (I work from home) and so much pain in my chest and back I thought I was going crazy. Day 6 was the final straw. Took my dose at 5pm. By 5.30, had severe esophageal tenderness that even drinking water hurt! That night in bed I was jolted awake with tingling in my left foot and stabbing pain right side of chest. I have 1 more day of antibiotic course tomorrow, but I'm going to talk to my GP and say I'm not taking another dose of PPI. F 39 6 days
20mg 2X day
7/6/2023
Email
 1  Too much stomach acid, IBS, hernia I have always had stomach issues. I was having an IBS flare up and my doctor ran some tests. I had 7 ulcers, gastritis, and bloody stools. I was prescribed this medication to reduce stomach acid. On the second day I started having headaches and heartburn, which I hadn't felt in years. My appetite was shot. I was basically surviving off oranges. It made my diarrhea worse and the most painful gas set in. Can't sleep or if I do it's brief. Constantly thirsty and frequent urination. I started having heart palpitations, muscle weakness and pain, brain fog.... It's been total hell. I ended up feeling way worse then I ever felt beforehand. Please be very cautious if you choose to take it. Ask for another option if you start having these issues. F 47 7 days
40mg 2X day
7/5/2023
 1  Acid Reflux Extreme weakness and fatigue, shortness of breath, blurred vision, muffling of hearing, diarrhea, bloating, anxiety, panic, feeling of dread/doom. Provoked an extreme flare of a chronic illness. I had one night of insomnia due to a sudden bout of regurgitation and my doctor suggested Prilosec. Nothing seemed out of the ordinary the first 6 days, but then all the sudden all the side effects set in and I've been mostly bedridden for the past 3 days feeling like I've been struck with the flu yet have no signs of an infection. I am chronically ill, but this is the worst flare I've ever felt since diagnosis years ago. Too sick to work for the past 2 days. Had to make a trip to the store to pick up something and had a major panic attack just driving there and felt like I was going to pass out in the store; not like me. Going to stop taking immediately today after reading all the similar stories here. M 32 9 days
20mg 1X day
6/4/2023
 1  GERD Extremely tired, sad, crying, feeling like I was going crazy, very cold I took Prilosec about 10 years ago for GERD and didn't have a problem. However, this time is different. I woke up two days ago with a huge anxiety attack. That has never happened to me. I am normally a pretty calm and carefree person. Ever since then I have these crying spells where I just want to be better. I'm so tired all the time, and even after I take a nap I feel like I could still sleep. I truly feel like I'm going crazy. These side effects are not listed very well (at least not where I have looked). After I found this page, I decided I'm not going crazy and it has to be the Prilosec causing all of these. Today is the first day I have stopped taking it, so hopefully I will improve mentally. F 36 16 days
20 MG 1X day
4/27/2023
Email
 1  Gastritis Extreme nausea, stabbing stomach pains, life-altering anxiety and depression, weight loss, no appetite, insomnia, heartburn. Worst experience of my life. This pill should be illegal! I was prescribed omeperazole after getting gastritis. After about 2.5 weeks on the medication, I began to go severely downhill. Insane nausea, stomach pains, that would not cease. I also started getting very intense anxiety and would pace my house literally all day and night, trembling. I still didn't know it was the omeperazole! Went to my GI, had every blood and stool test imaginable done, had an upper endoscopy done which revealed a perfectly fine stomach, had ultrasounds of all my organs done, etc. Everything came back fine. But I was going downhill and fast. In a matter of 6 days, I lost 14 pounds. Then something clicked and I thought about the only common denominator: omeperazole. I went online and realized I wasn't alone; so many people have experienced the same symptoms: nausea, stabbing pain, weight loss, insane anxiety and depression, etc. I went off cold turkey that day, even though they say doing so in that fashion can be dangerous due to rebound effects. I immediately started feeling better. The nausea, stabbing pain, etc., went away! The anxiety has been slower, but I'm getting better every day. It's been about 4 weeks since I stopped the awful medication, and I am almost back to normal. The anxiety has taken some mental work to get through but you can do it! Do not take this medication! And if you have and have experienced these F 36 4 weeks
40MG 1X day
4/22/2023
 1  For Acidity I took 11 Omeprazole caps for 11 days and have symptoms like stomach cramping, lack of appetite, bloating, lack of sleep, tarry stool's and dry mouth. Even after stopping it, today's 11th day but still having stomach cramping, bloated, lack of appetite. Horrible medicine. F 65 11 days
20 mg 1X day
3/23/2023
Email
 1  For Acidity I took 11 Omeprazole caps for 11 days and have symptoms like stomach cramping, lack of appetite, bloating, lack of sleep, tarry stool's and dry mouth. Even after stopping it, today's 11th day but still having stomach cramping, bloated, lack of appetite. Horrible medicine. F 65 11 days
20 mg 1X day
3/23/2023
Email
 1  Gastrointestinal issues Hot flashes,cold chills, complete loss of appetite, insomnia I was doing ok until I took this medication, I feel like I have been poisoned M 40 3 days
20mg x1 1X day
2/20/2023
Email
 1  Reflux Anxiety and depression. Very dry eyes. Brittle nails. Depression and anxiety have increased. My eyes are burning in the night no matter how much eye gel I use. I feel like I'm in a dark emotionless hole. F 69 30 days
20 mg 1X day
1/22/2023
 1  Gerd I have commented on this forum before. I thought I would come back on to give an update. I have had pulled muscle sensations in both legs for a year and a half now since stopping this medicine from hell. I was hoping that by now these overworked, pulled muscle sensations would be gone but they still bother me to this day and I only took omeprazole for a week. Please, please, please stay away from this medication. It is truly the worst thing I've ever done. I was previously very active and now I struggle some days with the discomfort I get in my legs. Don't take this stuff if your life depends on it! It is so damaging. I hope I recover fully from this. Any person I have spoken to about this do eventually recover but it can take years. F 31 1 weeks
20mg 1X day
1/15/2023
Email
 1  GERD/Hiatal Hernia Severe Anxiety/depression, panic attacks, shortness of breath, loss of appetite, stomach pain, muscle fatigue, nausea, chills, sweating, clammy hands/feet, bad taste in mouth I have been healthy and happy my whole life. I was diagnosed with GERD and a Hiatal Hernia (runs in my family). I was prescribed 40mg of omeprazole a day for life. I took it for 2 months and everything was great, my symptoms were gone and I had no side effects. I was off of it for a few days without withdrawal symptoms because I went on vacation and forgot my meds. I came back and started taking it again. 2 days into taking them I was just standing around and I had a horrific panic attack out of nowhere. I almost passed out about 5 times in the span of an hour, I had chills, I was shaking, I could barely breathe, my heart was racing. So naturally I went to the ER. All of my tests came back perfect. I then talked to my uncle (who is a doctor) and he told me it's just anxiety, and that I must be stressed about something in my life. The only thing is that I'm happier than I've ever been at this stage in my life, and ive never even had anxiety or depression. Theres no way that 2 days into taking the meds again, I feel these side effects without them being correlated. Every doctor ive spoken to has said that omeprazole doesnt cause side effects. This pisses me off because I know my body better than anybody else, a PhD doesnt make you god. I stopped taking the meds a few days ago and have started taking B12, magnesium and 5htp supplements to combat the sever anxiety that I'm feeling constantly. I've also decided to abandon prescriptions for my GERD and am trying to change my diet. M 25 2 months
40mg 1X day
1/8/2023
Email
 1  GERD After the 10th day, I had a sudden panic attack (seemingly out of nowhere), my whole body was trembling and my body got very cold - then just a few minutes later incredibly hot and my ENTIRE body started sweating heavily. And when I say heavily, my wife saw sweat pouring from my face like I had just taken a shower. I'm glad I found this forum, because I'm shocked to see how many people have experienced the same thing. M 34 10 days
1X day
12/6/2022
 1  Possible GERD Panic and anxiety attacks, Hot flashes, Face and arm tingling, insomnia, night sweats, weight loss, upset stomach, yellow poop, loss of appetite, and many more 5 MONTH UPDATE: I am happy to report that after several months all symptoms are gone! Weeks 1-2 were the absolute worst by far. I was suffering from every symptom mentioned above constantly. After about a week, I noticed the near constant anxiety, panic, and depression. (never had any of these before pill) tapered off quite a bit. Stomach was on fire like a swallowed lava after I quit taking the pill, my appetite did return and I started to eat again. I lost 15 pounds that first week from not eating and I’m not a big guy. Weeks 2-4 I still had all my symptoms, it’s just they weren’t as intense. The extreme fatigue was gone. I think I had my first day around week 3 where I almost felt good. Week 4-6 Many of symptoms started to disappear and fade. The night sweats were gone. I was sleeping better. Waking up a lot, but at least getting 5-6 hours a night. Sore tongue was gone. Dizziness and brain fog were fading quickly. Burping was gone. Sour stomach, nausea and hot flashes were fading. I was having a few more good days. Week 6-8. All my symptoms were gone or fading. Headaches are gone. My stomach issues are 98% resolved. Months 3-4 The face and arm tingling remained for the next 2 months. I thought I had permanent nerve dame but it just a really long time for them to completely fade away. IT DOES GET BETTER, IT JUST TAKES A LONG TIME! M 49 8 days
40mg 1X day
11/9/2022
Email
 1  Acid reflux at night Dizziness, bright yellow stool, problems with digestion, nausea, problems persisted 2 months after I weaned off it and then went away My doctors didn't believe my symptoms were side effects of the meds F 46 21 days
1X day
10/22/2022
Email
 2  Heartburn Diarrhea since day one , no appetite still have heartburn , on day 3 body aches chills will stop taking it! F 33 3 days
20mg 1X day
8/30/2022
Email
 1  Heartburn achy legs like I have never ever had before! F 59 6 days
1X day
8/10/2022
 1  Extreme sore throat, regurgitation It was WONDERFUL- for the first 3 hours - and then it hit. HR started increasing, insomnia. When I'd fall asleep, I'd jerk wide awake with racing heart. Worst migraine ever. Body chills. Aches. Back and hips hurt. Tired. Fever of 101! Hoping this stops soon!! Don't use this drug!! F 36 1 days
15 1X day
7/16/2022
 1  Silent GERD Hot flashes, chills, feeling hot, burning, tingly in face, loss of appetite, panic attacks, anxiety, insomnia, night sweats, loss of interest Was prescribed Prilosec for possible silent GERD. Thought 40mg was high for a first time user. Starting having chills and hot flashes. Thought I may be sick but no fever. Started feeling anxious and panicky. More hot flashes and chills lasting minutes to hours. On day 3 I felt so panicky and hot I almost went to Urgent care. I am usually a happy, upbeat and motivated person. I do not feel like myself at all. I don't feel like doing my usual daily things like work and exercise. I also love to cook and eat food. I have had no interest in eating which is weird for me. My sleep has been horrible. Insomnia and night sweats for days now. Had doctor ran blood and urine tests. All came back fine. Hot flashes and burning, tingly face continues. Feel like I am going slightly crazy. DR Google brings back very little for chills and hot flashes with NO Fever. Thought I might be going through "Man-o-pause" with the hot flashes and feeling hot since I am a middle aged guy. Then I stumbled across this forum and was shocked some of you describing the exact same symptoms as me. Perhaps it is just mere coincidence that many of you are experiencing very similar symptoms. Perhaps I do have something else going on medically that I don't know about. I will continue to investigate with my doctor. It just seems very odd that all this started with this medication when I have never been like this my whole life. I have only taken it 8 days so far but have stopped taking it today and see M 49 8 days
40 MG 1X day
6/2/2022
Email
 1  Mild gastritis, esophagitis, reflux Did not notice improvement in symptoms while taking this. Had an increase in reflux symptoms after weaning off, with many symptoms I had never had before I started- nearly constant reflux, lump in throat sensation, increase in epigastric pain and some chest pain while eating. Have been fully off for one and a half weeks. F 35 50 days
40 1X day
5/17/2022
 1  Esophagus Ulcers Severe debilitating anxiety attacks. Dizzy. Headaches. Pins and needles in mouth and throat. Deeply sad. Worsened abdominal pain. Gas and bloating increased. Can't think clearly. I have been fighting with sharp abdominal pain for years. Keep trying to get help. Diagnosed with ulcers in esophagus 2 days ago. Was told prilosec might help. These awful side effects are so bad in some ways they're just as bad as the severe abdominal pain in fighting. They're not worth this feeling like I'm going insane. Prilosec also has too many other possible risks that could cause even more problems to your physical health. Don't take this dangerous drug. It should be discontinued. F 54 1 days
20 MG 1X day
4/8/2022
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PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

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