NULYTELY Reviews (POLYETHYLENE GLYCOL 3350; POTASSIUM CHLORIDE; SODIUM BICARBONATE; SODIUM CHLORIDE)

Average Rating: 3.2 (411 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on NULYTELY: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR NULYTELYCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Colonoscopy prep Nausea, gagging, bloating, bad chills and eye-watering. Tip: Do NOT chug. Sip it. And NOT through a straw either. If that doesn't work, hold it in your mouth and toss it back 3 times until it's completely swallowed. It's the same principle as swallowing a horse pill with water. I'm amazed by the polarity of comments here. For the people with high thresholds for punishment, good for you. But this was THE hardest thing I've ever had to in my life (until I had to take my own stool samples). I drank HalfLitely. The flavor packet I used (Citrus Berry) did not make the solution taste any better. If I had to describe the taste of it, it's like drinking salty baking soda water with a hint of fake fruit flavoring. I drank it EXACTLY as prescribed (8 oz every 30 minutes for 4 hours split up in 2 sessions). My bowel movements were surprisingly non-urgent. I actually had to force myself to go each time. The HalfLitely did what it was supposed to do; made my stool look like urine. I managed to get through the whole jug without vomiting one time, even though I considered chucking the last few ounces. In short, I would NEVER... EVER drink this again. It's VILE. I wouldn't even wish this kind of torture on my worst enemy. The person who created this solution should be strapped down into a chair and forced to drink it so that noone will ever have to endure such misery again. M 99 1 days
8 oz 8X day
3/14/2010
 1  cleansing-pre colonscopy I have spontaneous bleeding of bladder as a reseult of radiation treatment for prostate cancer. This condition is worsened by such things as aspirin (which I no Longer Take). Twelve hours after completing cleansing procedure I had a great deal of spontanous bleedilng of bladder. More than ever experienced before. this continued to a lesser degree off and on for a week. I believe, without a doubt, that one or more of the ingredientsaffected my bladder condition. I will take another colonscopy only if the doctor agrees to use another cleansing agent. I know some doctors use other products such as Fleet. M 78 1 days
6/21/2004
 1  colonoscopy prep drank this poison on 7/7/15, close to death for 6 months, I now have chemical colitis and permanent never damage that is incurable as per my physician. From my mouth to my rectum was burned from this poison. I have spent my entire life savings on treatments trying not to die. The only reason this is given to medicare pts is because it is the one medicare will pay for. In my past I had 7 other colonoscopies without a problem. This drug has destroyed my life from what I had prior to taking the drug.I am basically a shut in a go only to the doctor or to purchase supplements.It is always about money for the drug companies, not for the safety of the patients. My advice to everyone is don't take this poison as there are many gentle cleansers available, medicare just wont pay. F 77 1 days
1X day
1/4/2018
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 1  colonoscopy Soon after a colonoscopy procedure on 6.5.07 I became aware of fatigue and chest pressure with exercise. A primary doctor appointment was scheduled. A blood test revealed "renal insufficiency" with 2.2 Creatinine and 10.5 Hemoglobin levels. I next proceeded to a urologist and an ultrasound of kidneys, tract and bladder which revealed nothing unusual. A week later a nephrologists diagnosis was "acute not chronic renal failure" with some kidney self repair indicated by blood tests. The nephrologist questioned me on "what major medical event" had transpired since perfectly normal blood panels on 2.23.07. I had no major issues to advise and did not consider a colonoscopy as “major medical event”. The nephrologist suggested a prompt visit to a hematologist. A hematologist’s diagnosis on 7/20 was a acute kidney reaction to my colonoscopy bowel prep Nulytely (4 liters). I am now on a regimen of blood testing and a synthetic hormone, Arane Difficult product to injest over required 4 hours. M 75 1 days
9/18/2007
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 1  colonoscopy prep Absolutley Horrible! The taste is disgusting and iit is so nauseating. The only reason doctors use this vile chemical is because in the case of Medicare, that is what they approve. Guess why? It is all about MOney! The insurance companies dictate what meds we can and cannot have, not the doctors...Drank this most horrific solutions, cleaned out, lost 6 pounds in less than 24 hours, vomited, had a migraine headache and a full blown Meniere's attack. My gut was completely robbed of all good flora. I have been taking pharmaceutical probiotics for a month and my gut and stomach still feel as though they are being eaten from the inside.. I have had 7 i.vs trying to replace the fluids I lost. Tuesday will be exactly 4 weeks and I am still very ill. I did call the company but all they wanted to know was what color is the label? they didn't seem concerned at all. Adding that I am 74, female and weigh 110-112. I have had 5 previous colonoscopies with no problem what so ever with the prep F 74
1X day
8/2/2015
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 4  Colonoscopy Bloating and chills until I started eliminating. Taste is not horrible to me - I don't have a strong gag reflex either. (actually the last three or four portions were horrible) Drinking a little warm or hot water after each glass helped me to relax and took some of the chill of me. It didn't begin working it's magic until I had drunk well over half the jug. This is my 3rd colonoscopy, the first time I waited until my bottom was sore to apply any ointment - big mistake. 2nd time I applied Desitin before starting and kept applying it until I was done. Desitin is very messy and got through my shorts onto my trousers. This time I used A&D ointment, baby wipes with aloe and put on some Depends. M 72 1 days
4L 1X day
11/21/2014
 1  For a colonoscopy HORRIBLE!!! Entire body is swollen. Can't even move ankles. Legs twice their normal size. My butt hole is inflamed & itches like crazy. Sores all over my mouth & lips. Even though I am high cancer risk I will NEVER do this prep again!!! I started this @ 3:30 p.m. the day before & was up all night. It took over 10 hours & still could not do the last 2 cups. It even said not to but it down the sink. That should tell you how awful this is on your body!!! Very bad side effects. Started the prep Sunday & it's Wednesday & still feel bad!! Still swollen & problems with my butt. M 71 1 days
3-4 Liters 1X day
4/25/2012
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 1  colonoscopy prep Slight chills for first 2 hours Yucky stuff. Took it with the orange flavoring. Took it all in about 5 hours. I have a stoma so it was not as bad as some folks had it at the other end. Still a word of caution. The pouch fills up quickly at times so you don't want to leave home. For you stoma viewers, colonoscopy was easy with a 2-piece pouching system. M 70 1 days
1/8/2008
 5  colonoscopy none I ate a low residue diet for 2 days and an all liquid diet on prep day. Made the trylite UNFLAVORED in the morning (flavors all smelled horrible)and chilled it. Took 2 ducolax at 2:15PM and started the trylite at 5:15PM, 8oz every 15 min. Drank it cold, in an 8 oz glass, through a big straw (MacDonald's)and sucked lime wedges before and after every glass. Made a BIG difference! Tasted like weak flat alka seltzer or weak bicarb of soda, almost tasteless, with a zing of lime. The consistency was NOT thick (like the horrible cherry golytely was 10 yrs ago); it was not bad at all - kind of refreshing on a hot evening. When I felt full after about 2 liters I stretched time to 20 or 25 min for a couple of times and then back to 15 min. After I started to go (walked around to get started)the bloating went away. It took the full 4 liters in 5-1/4 hours to get clear. Finished at 10:30PM, then up all night to go, and had procedure at 7AM. That was no problem. Felt fine afterwards and went to IHO F 69 1 days
6/28/2008
 4  Clonoscopy Mild bloating, slight nausea, no cramps, some chilling at first until liquid warmed up. Not as bad as expected after reading other comments. Boated for the first few glasses but OK after the first bowel movement. After some experimentation, found the best method was chugalugging. More palatable if taken on the side with Crystal Light lemonade. Finished the 4 liters in about 3 hours. Started defacating after the 8th glass. Turned cloudy yellow after the 12th glass. Took about 25 to 30 bowel movements to completely evaculate the intestines. Next time I hope they either develope a tasteless version or in pill form taken with 4 liters of plain water. M 69 1 days
7/25/2005
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 3  Colonoscopy Nausea & bloating, which went away after the first expelling. Sore bottom, but prevented soreness with Balmex before starting and after each expelling. I think that the orange flavor is the best for me Keep it very chilled & chugalug it. Follow it each time with a cup of any clear liquid. I took it every 30 minutes starting at 2PM. I had to sit on the throne after the first expelling. There is no warning after that. I just take a book in with me. It took all evening. I, too, would love to be able to take pills, followed with water. The taste is the worst vile thing with which you have to cope.There is an awful aftertaste. I have had to do this for 3 colonoscopys (ies?) in 4 years! It is not very pleasant & I consider it an ordeal. F 69 1 days
7/28/2006
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 5  Colonoscopy this is my 3rd colonoscopy. Before I took go lightly which seemed thicker and tasted salty. So far this solution seems lighter and easier but takes longer to work. I sip a little 7up before and after each glass, more like a mouthwash really I'm not done and I was scared too even had some "D" this morning from nerves but this seems ok. Also use A&D ointment often find in baby section, very soothing. Some day they'll have an easier way we can only hope😛 F 68 1 days
8oz every
8/5/2015
 5  colonoscopy prep None OK this stuff is gross. I used all four flavor packets (I've got a sweet tooth), and the taste was not unlike lemon/lime 7UP. Of course it is thick and salty. I found that if I took sips, chased by a diet 7UP or a sugar free popsicle, it was tolerable. It took three hours to complete the entire 4 liter jug. That time included two successful, but not urgent trips to the john. By trip number three, at the end of the three hour ordeal, you know what, was clear. Industrial strength tp ( I used ultra strong Charmin "heavy doody"), and disposable wipes are recommended. I began by putting the drink in the freezer after mixing. At three is was prescribed that I take 4 Ducolax - I took 5. And at 5PM I began drinking the concoction from the freezer, almost like a slushy. I noticed that as the drink warmed it tasted grosser and saltier. After each sip, I would take a sip of 7UP or alternately a bite of the lemon flavored popsicle. This worked quite well for me. It is 10:52, I had another visit to the john at 10:30PM -again clear. I feel great, have played 5 hands of cards: gin; spades and hearts and I'm Looking forward to going to sleep. I'll probably have to go again- a little growling, but no discomfort. I think if there is anything to be learned from my experience, it is the importance of sipping as opposed to drinking the four liters. M 67 1 days
9/28/2009
 5  unexpected diarrhea w/blood Some chills half way through cleansing, put a jacket on for comfort. No nausea, bloating or pain. Hind end will become sore, use a cream on anal area often. Remember the less stool you have to pass the easier the cleanout will be. Listen to your doctor. Not nearly as terrible as this site suggested. Tastes like flavored mineral water.I used Lemon/Lime flavor. Took me 16 swallaws to make 8 oz. Had two bags filled with ice to keep mixture cold, followed by sip of 7-up, took 5 hrs to complete the whole bottle. Pacing helps move things along... F 67 1 days
3/20/2007
 4  Colonoscopy Stomach gurgled and I felt really full, but no bad effects from drinking a gallon+ over 3.5 hours. After reading a bunch of the current reviews on Nulytely I came to the conclusion that we all react similarly, but each of us is different. The flavor packets add nothing from what I could tell and the liquid is more viscus than regular water, and slightly salty. This was not a pleasurable experience, but now it's over and it worked. Hallelujah, I'm clear at last! M 67
1X day
9/8/2014
 3  Colonoscopy Prep Extreme bloating and failure to eliminate for the frist three hours. Very uncomfortable I have done a prep in the past but it was with pills and liquids. This did not start taking effect for three hours and it became almost impossible to put any more in my distented stomach. At that point I lengthened the time between glasses. It took me 4 hours to drink the gallon. When I finally did start eliminating, i never really felt any cramps or urges, just started to run out. It would have been better if I had known that this effects people in many differnet ways. All the instructions say you will start eliminating after one hour, or three glasses, so when three hours pass and you feel like you are going to burst, you wonder if this is normal. I did not find the taste as bad as having to take so much liquid in such a short span. I believe if you start eliminating sooner you don't get the uncomfortable bloat. And in the end I was not on the throne that much. Again, I would have felt better if I had been given more information. F 67 1 days
4 litres 1X day
8/7/2011
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 3  Colonoscopy Still taking it. Half way through. I am hungry more than anything. I used the orange flavor and it helps a lot and of course keeping it in the refrigerator over night. The taste isn't to bad. I am just tired of drinking the stuff. Drinking 8 oz. every 15 minutes. I will be so glad when I am through. I am drinking cranberry juice in between and it helps. Will be glad when things turn clear. I feel like the muddy mississippi river is coming out of my body. Hang in there everyone, you can do it. Someone should make up T shirts stating I survived this stuff. I thought about adding a little bit of Bourbon in each glass. That would make it taste better and after awhile you wouldn't care how long it took Good luck everyone. M 67
4/18/2007
 2  upper and lower GI horrible cramps for hours before it worked.and horrible chest pain and hard time breathing until I took prescription pain meds.i take for bone pain.it scares me to death as my upper and lower GI is tomorrow F 67 2 days
2000 2 day
6/2/2020
Email
 2  colonoscopy prep nausea, vomiting In preparation for the colonoscopy, I ate lightly two days before. The day before, I stuck to the liquid diet and took 4 Dulcolax at 3 p.m. I started the Nulytely prep at 5 p.m. I used the lemon-lime flavoring, but couldn't really taste the flavor. It was neither good nor bad. I drank 8 oz. about every 15 to 20 minutes, until about one-half way through. I then started vomiting. I got a little more down -- I think about 2/3 to 3/4 -- and then vomited every time I drank it. I stopped drinking at about 10 p.m., but had not had a BM. (At this point, I started gagging just by looking at a glass of Nulytely.) Finally, at about midnight, I had my first BM. And at about 2:00 a.m., I started eliminations for real. This lasted until about 3:30 a.m. I had to be at the hospital at 6:00 a.m., where they went ahead with the procedure, even though I wasn't entirely cleansed. The doctor said that I had a recumbent intestine, and explained that it was extra long with extra folds, so it took longer for the Nulytely to get through my system. This explained the vomiting -- the Nulytely had nowhere to go, once I had drunk the initial one-half -- as it was traveling through my system at a slower rate than I was drinking it. It also explained the period of time it took for me to have my first BM. Although the doctor found no polyps, and irrigated as he went, he said that he would rate my colonoscopy as only fair, due to the inferior cleansing of my intestines. M 67
4/24/2009
 5  colonoscopy prep mild cramps, mild bloating, anal irritation (which might be from sitting around with a wad of TP stuffed up my butt, just in case I can't make it to the throne in time) Lemon-lime is salty and displeasant but not as bad as expected. (But it would NEVER make it as a drink you'd choose to buy!). 3 liters in 2 hours got me to the desired result. Take a deep breath and chug it chilled with nose pinched. It kicked in around the first hour with little warning. At this writing (about the 4 hour mark) the bathroom trips are frequent (5-10 minutes apart) and urgent. Think: firehose. I am now VERY curious what the rest of the night will bring. M 66 1 times
10/19/2006

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