PROMETRIUM Reviews (PROGESTERONE)

Average Rating: 3.1 (568 Ratings)

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 ESTROGENS PROGESTINS

 Type: Rx Drug

  

PROMETRIUM  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.   FDA Approval Date: 1999-10-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROMETRIUM: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROMETRIUMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Peri menopausal Breakthrough bleeding all the time. Always thirsty. Felt angry and very moody. Bloated and farting, stomach feels like its getting period all the time. I was taking the topical estrogen gel and felt so calm and happy on it. Then I had to introduce prometrium which instantly made me feel angry and moody again. F 47 20 days
200mg/day 1X day
9/23/2023
 1  Menopause It was fine at first. After a few weeks I started having horrendous Depression and anxiety. I wanted to cease to live. This was an absolutely horrible experience that I wouldn't wish on anyone. F 54 4 weeks
1X day
9/17/2023
 1  Peri menopause Horrendous!! Now I'm reading the other reviews it's the same as what I felt! So so depressed and suicidal thoughts: Today was awful and thankfully appt with my doctor and I'm now off it: I tried it orally and vaginally on two sep occasions(most recent vaginally) and not better. Not only did I feel like I was hit by a bus in the mornings, but the depressed thoughts were incredibly severe, hopelessness and suicidal thoughts were prob the worst I've ever felt. Horrible med F 51 12 days
100mg d 1X day
12/16/2022
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 1  Perimenopause Anxiety and panic Sweating Frequently urinating I tried this medication twice. I will never touch it again. First time, last month I used it 200mg vaginally at night and after two days I was very depressed. I tried it last night 200mg orally, and after one hour I woke up sweating and in panic. I had all morning full anxiety and I am waiting for it to clear my body. Why is this medication working in few women but not on so many. It’s horrendous! F 45 1 days
200 2X day
8/26/2022
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 1  Low prog in 1st trimester Severe depression, suicidal thoughts, crying, fatigue I have never felt the way I felt taking this medication and I have been through some tough times in my life. The depression and feeling of no longer wanting to be alive were strong. I went against my provider and stopped taking this medication. The moment you feel sad or depressed, stop taking this medication immediately! F 37 14 days
200 1X day
8/1/2022
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 1  Sleep problems from menopause Panic attacks gerd constipation F 52 100 days
100mg 1X day
6/23/2022
 1  Menopause. An awful experience (life threatening). Prior to this I had been on bio-identical hormones for 10 years after peri-menopause left me with no readable levels of estrogen, progesterone nor testerone. Advised that I'd be taking hormones for the rest of my life I chose bio-identical. It worked brilliantly - I'd remained slim, energised and happy and with no side effects whatsoever. Then my doctor suddenly retired and its a 6 month wait (in sth-east Qld, Australia) to get into see anyone who works in bio-identicals. So I opted for an online service in the interim, that replaced the bio-identical troche, with a Prometrium tablet, claiming it to be 'body-identical' yet the side effects are shocking. Its been an awful 3 monrhs. Although the first month of high nighttime anxiety and daytime dizziness has gradually lessened, I still wake every morning feeling like I've been hit by a bus. Groggy tiredness, heaviness, apathy, no energy, no libido, (NIL alcohol while on this because the waves of depression become suicidal), a constant headache and brain fogginess. But the worst side effect is the respiratory struggle, even after the slightest exertion. I'm now 'living' on an asthma spray (20-50puffs every day) and can't go anywhere without it. Some nights I wake hardly breathing. Exercise is out of the question. The prescribing service suggested doubling the estrogel to try to balance it. Now they've had me cut back the Prometrium to every second night. I certainly don't wake feel There is another webite showing reviews of prometrium as all extremely positive. Clearly sponsored. What a shame for those that ready that site for guidance. F 55 3 months
100mg 1X day
5/8/2022
 1  Menopause Skin rash that looked like chicken pox. Red itchy blisters which then changed into smaller itchy spots and by three months were less frequent but still appearing. I did some research and found peanut oil is in the ingredients of Prometrium. I am highly allergic to peanuts!!!! Why anyone would include peanut oil in a drug is beyond me. F 59 90 days
100 1X day
10/13/2021
 1  Menopause - to thin lining Horrible anxiety, panic attacks that I had never experienced before, waking up every hour at night with anxiety, crying, over emotional, loss of appetite, felt I needed to eat every few hours, dizziness and nausea. I couldn’t figure out what was wrong with me. Two trips to Er for them to tell me everything was fine. Thought I was going crazy until I read many reviews of women experiencing the same issues. The one positive thing to come out of taking this was it made me bleed which thinned my lining. F 60 8 weeks
200 1X day
6/18/2021
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 1  Perimenopause Horrendous depression and anxiety. Dizziness, weight gain. Apathy. Chest pain, muscle spasm. Please be careful when using this drug. I didn't know what was wrong with me and had no hope of recovery. The most scary experience ever. F 49 2 months
1X day
5/30/2021
 1  Menopause constant headaches, nausea, constant thirst, frequent urination, bloating, lethargy, depression, brain fog, decreased response to estrogen replacement, dry skin and brown spots on skin. Just awful, this drug actually prevented my body from using the estrogen pills/cream I was using and gave me added horrible side effects. No matter how much estradiol hrt I took I still had low E symptoms. 100mg progesterone for some of us is much too high a dose. Stopped taking prometrium and felt so much better, symptoms mostly resolved, in about a week and my hyperpigmentation is going away. I had endometrial ablation 10 yrs ago so my risk of endometrial cancer is almost zero and the risk of endometrial cancer is the only reason for taking progesterone hrt. Btw progesterone actually increases breast cancer risk and causes hyperpigmentation of skin but doctors don't tell you that. F 56 4 years
100mg 1X day
3/20/2021
 1  PCOS/induce a period About an hour after each pill I feel insanely dizzy and weak. I can't move my eyes or head quickly or I feel like I might fall over. I honestly feel like I'm drunk. My anxiety is at an all time high. I've been thinking my vitamin d was critically low until reading these comments. My hands and feet get numb and I get really cold after taking the pills and I am never cold. Absolutely will never take this again. I only made it to day five and I feel miserable. I've regularly taken other progesterone with no side effects. 0/10 would NEVER recommend. F 34 10 days
200 mg 2X day
3/14/2021
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 1  Endometriosis Severe anxiety depression, suicidal thoughts. Should be taken off the market shockingly horrific drug nothing like the bio identical natural progesterone that is compounded that I have always used.. F 50 5 days
1X day
2/6/2021
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 1  Peri menopause While on Prometrium I experienced anxiety attacks, broke out in hives and a tight chest which made in hard to breathe. - I experienced outrageous bloating and gain weight. F 45 50 days
100 1X day
10/4/2020
 1  Due to varicose veins on left ovaie Its being 3 days since I started taking it and my anxiety got worse last night I felt restless and very desperate. My eyes felt really dry This medicine made me cry. Horrible medicine. F 28 3 days
100 mg 1X day
10/4/2020
 1  Perimenopause Non stop headaches, sinus pain, heart palpitations & bloating My head was in pain for the entire time I took this medication. It started out as "regular" headaches, but became a combination of both a headache and a sinus headache. I did not have a cold, allergies or any other type of sinus conditions at the time. Also, the fast irregular heart palpitations were terrible. The word that best describes this drug is toxic. F 53 40 days
100mg 1X day
9/5/2020
 1  PMDD and Perimenopause Absolutely HORRIBLE !! The first month was Ok and then after that it was heart palpitations every night. The heart palpitations got so bad I felt like I was having a heart attack or stroke. Dizziness, headaches, brain fog, blurry vision, stomach pain, diarrhea and anxiety. This drug is horrible!! F 50 3 months
200 mg 1X day
8/17/2020
 1  Peri Menopause Severe Anxiety, Panic Attack, Fear of own brain, Suicidal images/worries, Unable to think of words in sentences, Brain 'flashes' resulting in extreme fear. It took me a while to work out what the culprit was. Always had general anxiety, never medicated. Went on Prometrium and all my troubles started ending with me having a full blown panic attack and spending the day in hospital.. Absolutely horrifying. Been off it for 2 days and am almost back to my normal (sane) self. If I'd only done more research before taking this drug I never would have done it. Been left with PTSD from my 10 day long 'nervous breakdown' which ended a day after I stopped taking this horrible drug. F 50 40 days
100 1X day
7/21/2020
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 1  IUD removal cause golf sized blood Headaches, dizziness, shortness of breath, increased heart rate. Havent taken it in 4 days and the side effects are still happening. My doc said it shouldnt be happening since the pills are only in effect for 12 hours. Had me tested for covid-came out negative. Problem still there! F 30 5 days
400mg 1X day
7/15/2020
Email
 1  Menopausal symptoms/low progesteron Horrible side effects. Dizziness, vertigo, feeling drunk, gums swelling, gums bleeding. F 48 5 months
100-200mg
2/15/2020
  

PROMETRIUM  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.   FDA Approval Date: 1999-10-15 (Sources: U.S. Centers for Medicare Services, FDA)

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