Drug Ratings for PROMETRIUM

Average Rating: 3.1 (503 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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RATING  REASONSIDE EFFECTS FOR PROMETRIUMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 5  Menopause Less muscle pain, brain fog, and improved fine motor skills / cognative function; some abdominal weight gain, other weight gain (which I can live with since the pain and fine motor skills / cognative function have improved). I already take something to sleep (trazadone) so, it really hasn't affected my sleep. Vivelle dot .50 mgs 2 X a week didn't help me very much by itself; doctor added Prometrium (100 mgs); no joy. Per "The Estrogen Alternative: Natural Hormone Therapy with Botanical Progesterone" [Raquel Martin], Progesterone ratio needs to be 125% to 1% for estrogen to be effective. Applied Prometrium topically 2 X and rotated location to areas of skin that is thin (forearm, wrist, tops of hands, back of knees). Also, now I just "forget" to use it; naturally cycle myself off. Interval between mood going to &^$# is getting longer and intensity of mood swings are less. Other things to also consider (as previously mentioned) is bio-identical thyroid medication (like Armour); and adrenal support (like Relora) and cortisol precursors like 7-keto DHEA and Pregnenolone. Yes, I have gained weight, but, was not active nor eating a "clean diet" (craved carbs - sure sign of weak adrenals); sodium / potassium not balanced? Water retention less severe since eating 2 blended potassium rich meals every day (lots of resources for blended meals on web). And exercise has helped with burning fat. (It takes a lot more energy to burn fat after menopause -- see "THE COMPLETE FIT or FAT" by Covert Bailey (great section of menopause) or one of "Zone" exercise books / websites. You are NOT exercising as efficiently as you think you are because some exercises are not effective for burning fat as you might think! F 55 180 days
100 2X D
10/22/2013
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 4  night sweats/peri-menopause Drowsiness, mild stomach cramps, lethargy, somewhat depressed, mild headaches. Had a period (I was told by my doctor that I shouldn't but it was at the beginning therefore waiting a while before worrying too much about this) I am hoping the drowsiness goes away as I am finding it hard to function. Unfortunately for me I had just started a new position and my head is in the fog. When I first began taking it I couldn't wait to go home to go to bed. I stopped going to the gym, had no energy. I have since gained weight, mostly in the stomach area. On the upside, since taking prometrium in combination with Estrogel, my night sweats have all but disappeared. I hadn't slept a full night in years. Now I pass out before being able to count to 10. I feel much better because I am getting some much needed sleep. Will be taking HRT for the shortest possible length of time. Just trying to get me through the rough spot I experienced. Before taking HRT, I was coping with acupuncture and homeopathic meds but in April, the floodgates opened and my entire system just went crazy on me. Night sweats were the worse (that and not sleeping a wink and trying to work full time). I am going to continue taking it and hope that the negative side effects disappear after a while because the pros are better than the cons for me right now F 52 30 days
100 mg 1X D
6/20/2013
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 4  Perimenopause Side effects only when dosage is off. Initially I had some irritability and urinary/bladder irritation and not much help with insomnia and fatigue I was hoping for. Now that my dosage is right, I dont have the side effects and it has helped with sleep, bloating and fatigue. I suggest anyone starting progesterone/prometrium start off at a low dose from compounding pharmacy. My first doctor put me on 100mg since that is the only dosage available unless you get it from compounding pharmacy. This was too high a dose and caused bad bladder irritation. I went to another doctor that prescribed progesterone in 25 mg dose so I could start out low and adjust as needed. I started on 50mg and didnt have side effects and it started helping with the bloating, skin itching/dryness, insomnia issues. When it started to lose efficacy, I increased to 75mg, and it worked well again. I am now taking 75-100 mg nightly with good results. Helps a lot with bloating/PMS symptoms. I cant believe some doctors are starting people on 200mg -- no wonder the terrible side effects! You have to ramp up slowing with HRT as the body needs to get used to it. If you had a bad experience, as I did initially, I would suggest trying again starting on a low dose. It takes a good 30 days at least with all the bioidential hormone replacement for the body to adjust and it takes some tweaking. Its worth experimenting to get it right if you are having extreme perimenopausal issues as I am having. BHRT has helped my quality of life, but it has required patience to get dosage right. Everyone is different and starting on lowest dose is best. You have to be your own doctor for the most part. Most doctors are ignorant and not very good at dealing with this issue... F 44 6 months
75-100mg 1X D
4/7/2013
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 2  Menoupause symptoms Racing heart, numerous hot flashes, insomnia, jittery feeling into the next morning. Tried this in combination with Divigel (estradiol) for mild menopause symptoms, the worst of which is insomnia. The very first night I took this I noticed side effects. It made my heart pound all night long and caused numerous hot flashes that woke me up every hour. During the night, I felt exausted, dizzy and loopy yet I could not sleep. I still felt jittery the next morning. Too afraid to feel that way another night, so it's going right in the trash. Too bad, because it's expensive! F 49 1 days
100mg 1X D
2/8/2013

 3  Post menopausal symptoms If you have side effects, you may have high levels of progesterone due to drug-drug or drug-food interactions. DO NOT CONSUME GRAPEFRUIT PRODUCTS! The CYP3A4 enzyme clears most of prescribed drugs (substrates) from your system. Check to see if any of your meds or supplements are CYP3A4 substrates and or if they are inhibitors of CYP3A4. Grapefruit stops the action of CYP3A4 gut enzymes completely in 30 minutes, permanently and irreversibly. You renew the enzyme in over 24 hours, so taking grapefruit products separately from your drugs does not help. When you can not clear substrates, levels of them get too high and side effects, even fatalities, may occur. Many herbal supplements are CYP3A4 inhibitors as well. Do not take them. Ginkgo, garlic, turmeric, for example. Research every substance for CYP3A4 interactions. Be well! F 57
100-200mg 1X D
1/27/2013
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 1  Perimenopausal OMG! I thought I was having a heart attack. 200mg Oral. Resting heart rate over 140 for 6-8 hours while sleeping, over 100 the next day. Vomitting all night, Sweating, so weak had to be carried to bathroom. Headaches.Stopped taking immediately. Cannot imagine taking for 14 days. Maybe it should have been a suppository at 200mg? on Estridot but goal was to create period. F 47 1 days
200 mg 1X D
1/8/2013
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 5  menopause No adverse side effects observed Sleep, glorious sleep! I'm fairly certain this is the first time I have experienced a full night of uninterrupted sleep in over a year. I also have a greater sense of well-being. Very pleased indeed and hope I can take it forever! F 51 7 days
100 1X D
8/31/2012

 3  PCOS Extreme dizziness, "drunk" feeling, constant headache, lethargy, uncontrollable crying, difficulty concentrating I hate having to take it, but it works in terms of helping me have a period. The first 2-3 days are the absolute worst. I can barely get out of bed and when I do, I walk around in a daze and anything will make me cry. I tried the 100 mg dosage which had less severe side effects, but I had to take them for a longer period of time (which I didn't like). So, I sucked it up and went for the 200mg. I take it before bed to help with the dizziness, but it still lingers the following day. F 32 12 days
200mg 1X D
8/31/2012
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 5  low progesterone after a TAH/BSO None other than menstrual type cramps. My appetite is wayyyy down, no more swelling in my hands and face! :) SO happy! F 45 7 days
100 mg 1X D
8/10/2012
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 5  Menapause symptoms none really helps with sleep My OBGYN who is a researcher informed that Prometrium is recommended along with Vivelle Dot to combat the risk of breast cancer. F 51 2 years
100 mg 1X D
8/7/2012
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 1  menopauase with premarin Nausea every day, stomach irritation, constipation, HEADACHE, pain in calves, blurred vision, sore ,enlarged breasts. It is hard to know for sure which drug is causing all these problems, but I think it is the prometrium, for the nausea and headache. It helped my depression, but I can't tolerate the side effects at this time. Will quit both and start to get rid of the side effects/ F 50 60 days
100mg 1X D
8/7/2012
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 3  Help with implantation after IUI Severe joint pain; fatigue; bloating; sore breasts; moodiness; F 39 2 weeks
200 mg 1X D
7/24/2012

 3  Low Progesterone/TTC Have to drink with a lot of water or it feels like it is sitting in my throat. Then I start to feel jumpy and tingly, eyes feel puffy- I just feel off after taking it. Heart flutters also. I do not feel sleepy after taking it, but dr. told me to take it before bed. Lay awake for a while. Then I have really weird and vivid dreams of people, places or thoughts from the day before. Wake up after 5 hours in the middle of the night and can't go back to sleep. Do not feel tired in the morning. I think it has opposite effect on me- makes me hyper. Not loving this but taking it to higher progesterone levels and in case I do concieve. I take it starting the third day after ovulation through day 12, and I assume will cont. if get a PPT. F 28 4 days
200 1X D
7/19/2012

 4  Panhypopituitarism Strange dreams. In this 3rd week of taking, I'm watching my stomach distend like a basketball. I am hoping this is temporary. Since becoming panhypopituitary (due to surgeries) in my 30's I lost all my hormones. I had to replace and balance so many other hormones and vitamin deficiencies that the doctors were not ready to deal with the female hormones until everythign else was balanced. That took almost seven years... seven years I would not wish on my worst enemy. In my first week on this 100mg of Progesterone and an estrogen patch I felt like myself for the first time in years. I slept without waking up 6 or 8 times like I had been doing and I could THINK clearly. All the awful night sweats stopped and all the uncharacteristic despair and crying went away. I no longer felt cold, old and tired 24/7 and wan't getting flustered over stupid little things. I even got a sense that my libido was returning. All was wondeful but now it's the third week and I can no longer get into any of my pants. If I see myself sideways in a mirror it looks like I swallowed a basketball. I also could not sleep at all last night with those old aches and pains and woke up to two pimples and I haven't had a pimple since I was a teen. I REALLY hope this is a temporary glitch because those 15 days/nights of feeling like my normal self again were the best gift I've ever received. F 45 17 days
100mg 1X D
6/29/2012

 5  perimenopause, bleeding, anxiety In the beginning - lethargy, depression, drowsiness, breast tenderness The side effects were in the 1st month only. Now I take Prometrium 100 mg 12-14 days a month, vaginally, before going to bed. In the beginning I had to use some Estrogel to get out of the depression, However using Estrogel led to extra bleeding/ spotting and anxiety, so now I am using Prometrium only. Lack of progesterone in the perimenopause is the reason women get anxious because of estrogen fluctuations, (Natural) progesterone down-regulates estrogen receptors thus reducing this sensitivity and diminishing anxiety. One more comment: progesterone creams and gels did not help me at all, since progesterone, unlike Estrogel, is not absorbed by my skin. Vaginal way is the best way to take it, also for endometrium protection. F 49 3 months
100 1X D
5/4/2012

 1  insomnia Put on this by my naturopath so I assumed it was safe. Foolish me! Slept terrible and woke up with a raging headache, nauseated and just feeling very strange. Decided that since I don't tolerate meds well, it isn't worth feeling awful 24/7 just to try to sleep better. Threw it away and will never try HRT again--will go back to using my natural progesterone cream that doesn't have any side-effects. F 56 1 days
100 mg 1X D
4/11/2012
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 5  PMDD Water Retention AMAZING!! Had horrible PMDD. It's completely gone. Not only is the PMDD gone but all the anxiety I was experiencing the rest of the month that I thought was normal is gone as well. I feel like a completely new person. I could be the poster child! My doctor put me on a low dose water pill which has alleviated the water retention. Also, my appetite has gone down tremendously. Its a win win for me! F 48 2 months
100MG 1X D
3/21/2012
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 4  sustain pregnancy tender breasts, drowsiness, cramps, swelling of feet and hands, shortness of breath my husband and I have been ttc for 2 years, miscarried in June 2011 and got positive preg test Feb 20, 2012, saw pregnancy on sono Feb 22 and have another appt March 5 to see heart beat. I cramp severely, but I believe its from being on my feet most days. Tylenol seems to relieve cramping, as long as I don't see bleeding I can handle it! I am only suppose to take this for 28 days....I will take it full term if necessary. F 31 28 days
200 mg 1X D
3/1/2012
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 5  Full hysterectomy at 27 I feel way better. The hot flashes aren't as bad. I'm breaking out on my face but I will take that over feeling like crap any day. I do notice that after I take it I'm a bit dizzy but that is a side effect. Overall very happy! F 33 1 months
100 mg
2/24/2012
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 5  Sustain pregnancy Have had 2 m/c and a hard time getting pregnant. This medication makes me feel so calm and mellow I'd keep taking it, besides if it lets me carry my baby to term I don't mind. It does make me super tired but I work from home so I'm lucky I don't have to even dress up and can stay in yoga pants all day! It does scare me to read about birth defects though F 31 2 months
100mg x2
2/16/2012

 4  menopausal My right shoulder and arm felt sore.I felt hyper alittle. My hair was so smooth after I took have to be careful I get migraines. F 53 6 days
200 mg
2/15/2012
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 3  thick uterine wall, peri-menopausal on the 17th day I had swelled ankles. The next day I had tremors with my right hand so bad I could not hold a phone nor pour water into a glass from a bottle. Doc said that neither of those was caused by this med. The next 3 days I had a powerful headache and felt "spacey" all day. nothing in the last 5 days. F 54 21 days
200MG 1X D
2/2/2012
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 2  Menopause symptoms Take a bedtime,feeling drunk and dizzy. Mornings feel calm and drunk. Face broke out within the 1st day. Need to rest all day. Feel worse on the meds depressed. Bloating, F 46 1 years
100 mg 1X D
1/28/2012

 5  Bleeding for 4 months thick uterine None, I feel wonderful! The bleeding stop after 4 days of using Prometrium. I am sleeping great and I wake up feeling happy and Energized! My OB-GYN put me on Prometrium just to see if the bleeding would stop while comtemplating the Cryoablation to stop the bleeding. I am so glad I tried Prometrion is working wonderfully for me I feel great I sleep great after 4 months of heavy bleeding non-stop. Another OB/GYN Did a D&C and put me on birth control pill but nothing work. MY new DR put me on prometrium before doing a CryoAblation and is working for me hopefully i wont have to do the Ablation. I will post later. This site is great it help me alot. F 45 10 days
100mg 1X D
1/24/2012
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 2  Jump Start a Cycle - no cycle 7 yrs I have not noticed any side effects. I have not gotten a period. My doctor recently upped my dose to 300mg per day, rather than 200. and increasing my estradial to double - thinking my lining wasnt thickening and nothing to shed. I really need to start getting periods, to start ovulating, to get pregnant. Anyone else have this situation? i am 35. no period since 2005. F 35 60 days
100mg 3X D
1/22/2012
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 4  menopausal symptoms none started on Prometrium because my progesterone level was 0.5, it has greatly improved my anxiety, constant sweating, and mood. I also sleep a little better. I am very glad I started taking the drug and I plan to continue! F 54 4 weeks
100 mg 1X D
1/5/2012
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 3  To get pregnant. Used injectables. Breasts are very sore. Acne on cheeks and forehead. F 33 8 days
1/4/2012

 4  Main pregnancy Really tired and cramping with a bit of lower back pain. Breasts are starting to get sore as well. I have had 2 miscarriages this year and I am currently 18 DPO going strong. I starting taking the medicine at 9 DPO and it seems to be working great. I will take the mild side effects if it helps me to go full term :) F 31 10 days
200mg 2X D
12/9/2011

 4  Perimenapausal symptoms hot flashes Gas pains in chest near heart daily. Acid reflux just started. Of course Thanksgiving could have contributed to that too. Migraine headaches located behind right eye. But have history of both acid reflux & migraines. I have not had a period for a few years. I had been on Femhrt 1/5 for about a year to treat hot flashes and waking up every few hours. It seemed to help a bit with flashes and sleeping but husband and I noticed I was becoming very short fused. New Gyn put me on estradiol 1 mg under tongue in AM and Prometrium 100 mg at bedtime. Felt better almost immediately. My only worries are the gas pains and continued migraines. F 48 25 days
100 mg 1X D
11/27/2011
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 4   F 64 8 years
100 1X D
11/10/2011

 4  To jump start my period Some nights when I took it I got drowsy, however it only last for about 2 hours. During the last few nights I got bloated. I was prescribed 400mg of prometrium, the pharmacy didn't have 400mg so I was given 200mg and just doubled up. I took it for 10 nights, its best you take it at night because it causes drowsiness. I started bleeding 2 nights after stopping the medicine. I'm pretty sure my doctor will prescribe it again next month, we're trying to make my cycles regular again after they just suddenly decided to skip 3 months. I will have no problems taking this medicine again. It did exactly what it was suppose to do! F 25 10 days
200 MG 2X D
10/30/2011
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 4  Sustain Pregnancy I have only been taking for two weeks but have to take for 12...body ackes, severe nausia, stomich pain, extreme tiredness but sleep deprevation, gas, diarea when i'm not constipated. If it weren't for the 3 miscarriages I have had I wouldn't think this was worth it but I'm farther along then i previously had been with some of the other pregnancies. I have hurd vaginal suppositories don't make you feel this bad, I am asking for them tomorrow. F 26 2 weeks
200 1X D
9/7/2011
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 5  Taking this with Divigel Estrogen A strange skin sensitivity on my hip area that went away in about a week. That's all. No other side effects. I look forward to taking this at night, as it gives me a sense of calm - not sleepy - but rather more like I had a glass of wine. Just calm. I do not experience any sleepyness or grogginess in morning. I have to take this because it offsets the effects of Estrogen gel. F 49 1 months
100 mg 1X D
9/3/2011

 3  prolonged bleeding during cycle Day 1. Was told that it would make me sleepy. WOW. I felt completely drunk. Wondering if this is normal for dosage. There is no way I could take this other than at bedtime. So far no other symptoms. F 34 12 days
400 mg 1X D
8/31/2011

 3  Stop frequent menstruation Gained 17 lbs in a month, severe depression, major bloat, Knocked me out within 30 minutes of taking it. Stronger than other sleeping pills. I had almost constant periods for about 5 months and was feeling very fatigued from the loss of blood. Prometrium stopped the bleeding and kept me from having a period from May until October. The only problem is I gained so much weight while on it and I was horribly depressed. I ran into an ex boyfriend recently and he asked me how I was and if I still had to take "that hormone." He told me he had never seen me that sad or bloated and was happy to see me these days being so happy. F 31 21 days
1X D
8/15/2011

 5  menopause none I am taking prometrium 100 mg orally at night. I am also on the vivelle dot 0.05. The mood swings have gone. I was a loaded gun. My symptoms with irritability and emotional lability at a #10. All gone now. the severe hot flashes are gone. (I think that is the patch and not the Prometrium that took the hot flashes away???) The wakening at night from the hot flashes is gone. The vaginal dryness and dry skin are not. Lots of lubs on the market though. The one thing that continues is the awakening at night. I also have difficulty falling asleep immediately now it takes up to one hour to fall asleep. stopped all caffeine for 30 days and the problems with sleep still continue. My libido has improved 300%. . Laurel F 60 1 years
1X D
8/10/2011

 3  Kick start my cycle. Bloating, weight gain, cramping I've missed 5 cycles since going off the pill so the doctor put me on to see if it would kick start me back into normal. I've been on it for 5 days now and am BLOATED and putting on weight although I'm hopeful it will go away once I get off. It does make me sleep better at night though. It doesn't seem to be working for the cycle but the doctor has indicated that I am peri-menopausal so that would be why. F 45 5 days
2 x 200 mg 1X D
7/23/2011

 4  to induce period Dizziness, drowsiness, bloating, soreness of breasts(nipples), fatigue, difficulty concentration, anxiety, mild cramps and tingling pain in lower-right abdomen and groin area, gas. Got period after 6th dose. I am ttc . I have PCOS and was on birth control until my laparascopy recently. I had the surgery to remove an ovarian cyst (and an ovary) and had two regular menstrual cycles afterwards. This time (3rd cycle) around I missed my period and showed negative on pregnancy, so the doc prescribed prometrium to bring on my period. I took the pill by mouth. M 29 10 days
200 mg 1X D
7/21/2011
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 3  perimenopausal symptoms Used alone I'm not certain of any side affects as I take prometrium with premarin (1x daily). When I take the two together (the last 10 days of the month) I have heavy, extended periods 0f 9-11 days,and i feel the usual tired, spacey, chocolate cravings asociated with having a period. But I also get some dizziness, and brain fog. I just discovered this site and I found out why I get dizzy and sleepy, my OB-GYN neglected to tell me to take this medication AT NIGHT! makes sense as I was having trouble sleeping and night sweats. I take a over-the counter sleep med, but I will try Prometrium at night to see if it works. I will ask my Dr. to lower my dosage as it may shorten the duration and strength of the periods i'm having. Thanks so much for your comments I don't feel alone anymore!!!! F 55 90 days
200 10X M
7/20/2011
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 2  perimenopausal nightmares I'm taking prometrium since I'm on an estradiol patch (the vivelle dot). No matter the dose or duration I am finding the prometrium intolerable because of the consistent, horrible nightmares - I can tolerate the other side effects. Is anyone else having this experience? It is clearly related to the prometrium because I have been trying it off and on for over 6 months now. I am at a loss as to what else to do to prevent uterine cancer and the estadiol has been a life saver for depressive symptom. F 55 14 days
100--200mg 1X D
7/13/2011
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 4  missed period dizzy, cramping, slight nausea, racing heart, odd dreams I only took the meds for a little over half the prescribed time as I felt as though I had a ball in my belly. Way BLOATED! I gained a few pounds (water weight) and was very cranky and emotional. I started spotting the day I started taking it, and did so until I stopped. The day I stopped I started bleeding like I was dying. I have never had cramps like these that didnt result in child-birth. and I'm bleeding through a super-plus maxi every hour, I switched from tampons as the super-plus tampons were ineffective after a half-hour. considering calling the doctor. If you can stand the violent period, I would say go for it. It works, it just hurts and is rather inconvenient. F 30 6 days
200 2X D
7/3/2011

 2  no period; start ovulation cycle Did not do anything. Took 200 mg each day and was supposed to get my period at the end but I did not. Nothing happened. Did not have many side effects, either. Was very expensive in addition to not working! Still have not gotten my period or ovulated. F 29 12 days
200 mg 1X D
6/29/2011
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 2  menopause Tired, lethargic, depressed, can't wait to go home every day and just lie down. I had the worst dizzy spell last night. This has been going on for a month and prometrium is the reason. And the doc upped it to 200 mg which I bought and will have to throw away, as the pills cannot be cut in half. I don't think it matters what time of day I take it. I have the side effects 24/7. F 54
100 1X D
6/24/2011
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 3  Dysfunctional Uterine Bleeding Fatigue, cramps I am only on day 3. I am instructed to take 1 po every night before bed. I am able to go to sleep easier, and have a very rough time waking up and getting out of bed in the mornings.I also am feeling cramps, but I am welcoming that, as I have had non-mentrual bleeding for 26 days. Dr. said this should 'reset' things and get my normal cycle started again. Not TTC or anything,just tired of this. It is my second period after having a baby 4 mo ago and he is optimistic this will get me back on track. F 26 10 days
200 1X D
6/20/2011
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 5  to regulate periods & help ovulate My doctor told me it would make you sleepy so take it at night, it didn't make me fall asleep but it kept me asleep which is wonderful because I can never stay asleep! I had to finish the full 10 days of it and then the next day I finally started :) I'm trying to conceive so I'm very excited and hopefully it will help its been good so far in doing its job! F 19 10 days
200 mg 1X D
5/22/2011
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 3  Heavy bleeding with clots for 16wk Dizziness, diarrhea, lethergic, blood sugar increase, muscle cramps at night, indigestion, general body aches, loss of appetite but feel bloated. Biopsy showed simple hyperplasia without atypia. Bleeding and clotting continued. Low progesterone levels which makes my estrogen level dominant. Lack of ovulating. Put on prometrium to stop bleeding. It took 23 days before I saw a significant change. Meantime went back to the doctor who wants to put me on the prometirum15 days per month and them induce bleeding to sloth off uterine lining. I just dont' know that I can go through the horror of the past 4 months feeling like I was wearing a diaper.. At the present time despite the side effects I'm going to continue on the regular dosage of 1 time per day (take at night) and will revisit taking it for only 15 days per month in June. F 54 35 days
100 1X D
5/20/2011
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 3  low progest. lev. in early pregnanc Fatigue, acne, feeling drunk, dizzyness, cramping, Some of the side effects are difficult to discern from regular pregnancy symptoms. F 25 17 days
200mg 2X D
5/18/2011

 5  Low progesterone levels This is my first cycle taking prometrium. For years I have had issues with spotting 3-4 days prior to actually getting my period. With prometrium, this is the first time in years that I have experience no spotting at all. I do find the vaginal mode of admin easier to tolerate than orally. When I took the drugs orally, I felt nauseous. I am now 15 days DPO. So far no sign of a period. I have had 2 miscarriages in the last year and am hoping for good things with this drug. Fingers crossed. F 38 2 weeks
100mg 2X D
5/13/2011
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 4  HOT FLASHES & INSOMNIA POST MENAPAU SLEEP IS MUCH BETTER. I WAS WAKING UP 4+ TIMES A NIGHT. I MAY WAKE UP ONCE DURING THE NIGHT NOW. MOOD IS IMPROVED. WEINING OFF ANTI-DEPRESSANT MEDS. FEEL REALLY GOOD SO FAR. I HOPE I CONTINUE TO FEEL THIS WAY. I TAKE THE PROMETRIUM 6 DAYS ON AND 1 DAY OFF, THEN RESUME. I DID NOT SEE ANY OTHER DOSAGE THE SAME AS THIS. I WAS WONDERING ABOUT THAT.... F 51 12 weeks
100 MG 1X D
5/13/2011
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 4  low progesterone, hashi. thyroid Why are my ratings not being posted, I posted 3 times now and they are not on the rating page? F 44 16 days
100mg 2X D
5/12/2011
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History
 3  maintain pregnancy muscle soreness, leg cramps at night, exhausted all day (almost fell asleep driving), bloated I had a miscarriage in October 2010 and what was thought to be a "chemical pregnancy" in March 2011. I am only 1 month pregnant now and my doctor immediately put me on Prometrium. What is strange is they called into my pharmacy a prescription to take only 200 mg/ 1x day vaginally and then bumped it up to twice daily at 200mg. I am considering not doing the twice a day only because I am soooooooooooo exhausted from the dose I take at night lasting into the next day. Just the thought of taking it again in the morning gives me chills. F 30 2 months
200mg V 1X D
5/10/2011
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 2  Delayed Menstrual Cycle So, far I feel fine. Yes, I do get sleepy, and truthfully I need the rest. However, reading different reviews I am scare of weight gain. My doctor advised me to take two before bedtime for three nights. this is my second night, and a little concern when my period will start. This is my first experience of missing my period other than being pregnant. I was shock to hear the linning of my uterus build up approximately 20, much thicker than the normal 7. However, I was relief to learn of Prometrium to help correct this situtation. Meantime, I feel like I am on stand by waiting for some results. I will follow up in two weeks, and pray this is successful. F 40 2 days
200mg 2X D
4/10/2011
Email
 1  Continual uterus bleeding dizziness, fatigue, heart racing,heavy flood bleeding, shortness of breath,severe cramps and migraine headache for days... I never had any of these symptoms before taking prometruim. I just had a period that was lasting 14-20 days. I have stopped taking it but 15 days later the migraine and shortness of breath are still here. I could not function at work on this medication. I went home sick for 5 days. F 43 10 days
100 1X D
4/10/2011
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 4  Endometriosis & Adenomyosis, curb b The first 3 days very tired and high anxiety. Anxiety is gone now but still tired in the mornings. Taking it vaginally for 30 days to then switch to day 15-30, perhaps change to a natural progesterone. Am very happy how it regulates my period. F 43 7 days
200mg 1X D
4/7/2011
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 4  regulate periods Felt good, I felt calm and relaxed on it, moods were so much better I was having a period every 14-18 days before my doctor put me on this, I was worried about mood swings, and weight gain. No weight gain, and my mood was great. My period was actually 26 day cycle with this medication, I hope this works for me. F 41 12 days
200 1X D
3/28/2011
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 5  unsastainable period strange dreams first 2 or 3 nights It is disappointing that this medication was unable to help for some but it was a good fit for me im 20 years old and due to PCOS i never started having periods i was sixteen before i started and that was only because i was sent to an OBGYN that perscribed birth control which actually did enable me to have a period every month but if i dont take it i dont have one i was uninsured for a year and a half and never had a period i was irritable moody i snapped at people for the dumbest things at times and i never slept very well always too hot or something but i started taking this medication and i have never felt better i sleep great at night and my mood is so much better and i also have even lost a few lbs. but that could be because i actually am sleeping a full 8 hrs a night F 20 10 days
100 mg 1X D
3/19/2011

 2  bleeding and thick uterine wall constant bleeding, headache, anxiety, nausea, diarrhea, extremely tired My new OB/GYN prescribed prometrium for me because I was having excessive bleeding - I had a very heavy period for 2 wks straight. At first there were no problems, I tolerated the medication well, but the bleeding continued. She then told me to increase the dosage to 200mg/day. I tried that for 2 days and the anxiety began so I switched back to the original dosage.I was fine until yesterday. I began to have heart palpitations, diarrhea, and anxiety. I felt weak, confused and extremely tired. Today, it is just worse.I took 2 librium today and it did not touch the anxiety. I was afraid to leave my house to run to the store for some necessities. To top it all off, I still have my period! UGH!!! I am so glad this site is here, I thought I was losing my mind! I am stopping this medication. I cannot tolerate the side effects any more. F 43 13 days
100 1X D
3/14/2011

 5  uterine wall too thick None I was so afraid to take this medication. I'm so glad I did. I ususally have high anxiety a couple of weeks prior to my period. With prometrium I had nothing but calm. I was also worried because I am prone to migraines. I experienced no migraines. I have been dieting and experienced no weight increase in fact I've lost weight. Take before bed time. F 38 12 days
200 MG 1X D
3/9/2011

 3  sustain pregnancy after miscarriage Really fatigued, have no motivation & all I want to do is sleep. Breasts are starting to get very tender too. Pink discharge from the capsule lining, it's gross. Was told to take 100mg in morning & 200 mg before bed vaginally. Don't know if it helped any, as I can't take a pg test for 3 more days yet. Fingers crossed, as I've had an ectopic (Oct 2009) and a miscarriage (Nov 2010). F 37 8 days
100 mg 3X D
3/7/2011

 3  balance estrogen, night sweats Inner tube feeling around my stomach, breast larger & tender for awhile, bloated F 60 28 days
30 1X D
2/27/2011

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