CLOZARIL Reviews (CLOZAPINE)

Average Rating: 2.8 (59 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

CLOZARIL  (CLOZAPINE):  See also Warning section. This medication is used to treat certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine is a psychiatric medication (anti-psychotic type) that works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. Clozapine decreases hallucinations and helps prevent suicide in people who are likely to try to harm themselves. It helps you to think more clearly and positively about yourself, feel less nervous, and take part in everyday life.   FDA Approval Date: 2019-05-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3


More on CLOZARIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CLOZARILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  schizophrenia The First year or so, alot of drooling, very tired. Major weigt gain. Id rather be ovedrweight than psychotic. great efffects though from the voices. Been on it since 1992. Been on them all. This is the best. No more voices. M 44 16 years
12/17/2008
 1  Hearing voices It was horrible, it droves me crazy. In and out of institute 30 times. I got tardive dyskinesia. I was misdiagnoses badly. Psychiatrist love gives medications to people with out observation correctly. I had drooling, sleeping too much, diabetes, swelling ankle, couldn't walk, causes heart problem, high blood pressure, very obesity, zombie, paranoia, anxiety, high white cell count and in so much pains. I end up 38 pills a day. I got off all medications and I am back to normal except I got Tardive Dyskinesia. I am fight with that disease which had no cure. I am not on any medications now. I am suffering daily. I end up 38 pills a day. It had way too many side effect. I wouldn't recommend to offer that kinds of medications ever again to anyone especially to women. F 49 14 years
450 1X day
3/31/2017
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 2  Schizophrenia Intense sleepiness till mid-day, after a few years this side-effect went. Drooling on my pillow at night. became obese on this drug. My muscles are ineffective on clozapine. Expect my gait to be different to others. have become pre-diabetic because of clozapine. I don't want to be on this drug but have difficulty getting off this. Would like to say to anyone who is obese or fat on any drug, particularly this one, to ask their doctor to take a diabetes test. M 37 13 years
125mgs 1X day
6/17/2014
 5  bipolar depression super-intense weight gain via surge in appetite 45 mins-1hr later,bed wetting,extremely sedating,and drooling The ONLY reason I gave this med a 5 is because it is the only med in the universe that will put me to sleep.NOTHING else works.I do hate this drug for the side effects,especially the bedwetting and drooling.But what can I do?I need it for survival. The mandatory bloodwork is a major inconveinence and pain in the rump.The 2 good things about it are:no sexual side effects,and good for anxiety. M 12 years
12/13/2008
 5  Suicidal Sleepyness This was the last resort for me, my doctor tried recently to take me off it, but I went through withdrawl, my body hurt and my mind was all over the place so we had to put me back on it .when I amoved on the drug I function better and am in more control of my own actions. F 30 12 years
1X day
11/22/2015
 5  schyzophrenia drooling 1st 2years, constipation,eating sweets in the night,makes sleepy, hard to function in the morning excellent,wonderful, saved my mind F 32 10 years
12/28/2008
 4  Schizo affective disorder Slow metabolism, excessive drooling, dizziness I'm happy that the med has kept me free of Psychosis for almost 9 years..but not happy that despite all of my efforts, I've not been able to lose any weight in the past year. Am 34 pounds overweight.. F 61 8 years
200mg 1X day
6/2/2023
Email
 1  Delusions caused by heavy marijuana Anxiety, depression, weight gain Be very careful taking this drug. I was put on it to treat delusional thinking caused by heavy marijuana use. The marijuana caused severe anxiety, depression, and delusions. The clozapine caused just as much anxiety and depression. The delusions were gone, but that was probably because I stopped the marijuana. And the worst part is I was stuck on it because the withdrawal was so terrible. I was at 300 mg, and if I decreased to 250 mg, after a few days I would feel unbearable anxiety and had to restart. I kept trying to decrease slower, until finally I tried extremely slow tapering and was able to get off of it. It took three years of decreasing. I started at 300 mg, and I lowered it by an average of 8 mg per month. It took about a decade of my life away and had me laying in bed almost all that time. M 32 8 years
150 mg 2X day
6/20/2023
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 5  schizoaffective disorder Puts me to sleep at night. Drooling while sleeping. Very hungry at night. Only medicine that helps me fall asleep. M 35 6 years
200 MG
1/25/2016
 5  Schizophrenia Drooling, Sedation, Seizures I have to take a seizure medication with Clozaril because my seizure threshold is low. Actually, if I take any antipsychotic I have to take an anticonvulsant, so it's not just Clozaril, it's just that I have to take a higher dose on Clozaril. Ah, for the drooling, you can take (sublingually) the eye drops that they give you at the eye doctor to dilate your pupils. It stops the drooling. I take a couple drops under each side of my tongue before bed and I don't drool at night...nice. My doctor taught me that one. When I went to fill my prescription for the eye drops, I had to explain it to the pharmacist...lol. I don't get too much sedation, I mostly sleep it off, as I take the med at night. I've tried all the meds and this is the best one. It even helps the negative symptoms, which are mostly what remained for me with the other meds. I had a lot of problem with "connecting" to people, which affected my ability to form relationships with people and my interactions with people. Clozaril helps a lot with that so I can relate to other people and "connect." It is hard to explain, but it definitely helps me feel human. For me this has been a great medication. F 37 6 years
11/8/2009
 5  Bipolar 1 Drooling (worse in first few years), weight gain, craving for sweets especially after a dose at night, sedation that lasts way into the next day, too much time on the couch watching bad TV. Great drug for treating my terrible depression (suicidal thoughts) and for somewhat stabilising my rapid cycling. Hasn't fixed everything but I wouldn't like to think where I would be without it. At a time when I had run out of options it was a wonder drug for me. F 40 6 years
250mg 1X day
9/19/2013
 4  schizophrenia Tachychardy pulse around 100 diastolic pressure about 90 a little constipation Just to make a suggestion, try the blood test on your hand, i find it appears less than on the elbow M 35 6 years
300 1X day
12/13/2022
 1  Borderline Personality Disorder Sedation, Weight Gain, Apathy, Paranoia I took this medicine for 6 years. During this time, I felt absolutely dead to the world, and miserable. I gained 30 pounds and got scar tissue from the blood draws. I was forced to stay on this medication for far too long, and I cannot think of one positive thing to say about it. I have been off of it for about a year now, and I feel infinitely better. The withdrawal is absolutely terrible (severe headache, -extreme- insomnia, nausea, ect.) but it is definitely worth going through to stop taking the medicine! F 13 6 years
300MG 2X day
1/14/2016
 1  Schizophrenia I took this drug because i had no choice. I was in a high secure hospital and quickly realised i had to jump through ihoops if i wanted to get out of there. I had to tell them what they wanted to hear and take the meds. All i wanted was to be my spiritual self. Theres no such thing as mental illness its a state of mind, albeit one that can be difficult, i did not want my soul destroyed by digital machines and chemicals and bullshit psychology. I hope we make spiritual progress for the sake of our future generations. They should not have to be tortured for having a spirit. This drug clozaril will destroy a part of you. It will damage your physical self just as much as your spiritual. Its like being connected to a machine. You feel good at first, silence and peace. But once you come off it, you realise how they are stopping you from being your true self. I realise i was a zombie for 5 years. These people do not want you to think for yourself. What is more dangerous. Being dead inside. I Dont take it. Its the exact chemical opposite of ecstasy. After i have been off this drug for a while i start to get my natural thoughts back. But I cant sleep without it M 30 6 years
400 1X day
4/6/2013
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 5  Schizophrenia Very tired after about an hour after I take it. I get real hungry after about 20 minutes. Problems with dizziness. I need more sleep than before. But it has been the best drug I have had. Scared of what will happen if the blood work says I can't take it anymore, because this has been the only drug that has worked for my. I have been told I am a difficult case. And with this drug I haven't been hospitalized a little over two years. F 45 4 years
400mg
1/27/2017
Email
 5  Schizophrenia Very tired after about an hour after I take it. I get real hungry after about 20 minutes. Problems with dizziness. I need more sleep than before. But it has been the best drug I have had. Scared of what will happen if the blood work says I can't take it anymore, because this has been the only drug that has worked for my. I have been told I am a difficult case. And with this drug I haven't been hospitalized a little over two years. F 45 4 years
400mg
1/27/2017
Email
 3  Drug induced psychosis Bed wetting 3x. Drowsiness. Weight gain - up to 110kg now 64kg. Anxiety. Depression. Embarrassment. I was a drug addict from a very young teenager and constantly in trouble. I completed year 9 barely and attempted suicide at 15 with a dose of paracetamol at just about 63000mg. I was very infatuated with drugs, alcohol and my family life was unstable. I was molested as a child by my father 1 time I remember and again by him at 14. I was also raped in a caravan park at that age by a 37 year old man while looking for drugs and alcohol. This shaped me for the next few years into somebody I wouldn't recognise or want to today. I was introduced onto cloz* at 19 and I was and still am compliant. I have done a short tertiary course at university for 8 months, am part time employed as a support worker with a traineeship and hope to do a bachelor of nursing with hopes to work in an emergency department. However I am not getting support because of my achievements and how normal** I appear to be. I have moved forward with my life and grown into a mature responsible adult but I am suffering from anxiety attacks and moderate depression because I guess my past bothers me. I am embarrassed by it. I would like to try another medication. I do not want to be a mental health outpatient for the rest of my life because I haven't had my life yet. I am very driven and I am not where I want to be yet however I am slowly working towards being something I am proud of. I am getting frustrated because I pick up my prescription after a 3 minute chat to the lovely employees at mental health but I am not F 24 4 years
100MG
3/12/2017
Email
 1  Mental Illness Brain Zombie. Drooling. Bed wetting. Collapsing. Clozaril=Chemical lobotomy. Ban this drug. 41 4 years
900mg 1X day
9/29/2017
 4  Schizoaffective Disorder Extreme drowsiness 1 hour after taking 300mg at bedtime. Very hard to get out of bed with only 6-8 hours of sleep due to the clozapine still in my system. If I have up to 10-12 hours, I wake up okay and feel normal. Do not take huge dosage during the day. You may become very drowsy or even faint. Overall, I noticed a positive change in my behavior, thinking, and outlook on life. I feel stable. M 27 3 years
300 MG 1X day
1/5/2017
Email
 1  psychosis due to family tragedy I turned into an ignorant drooling zombie but did everything in my power to defend the drug no matter what anyone said to me. Don't take this drug. It destroyed my relationship with my partner. It was only after finally getting off this that I woke up and realized what I had been like. F 39 3 years
20
12/22/2014
  

CLOZARIL  (CLOZAPINE):  See also Warning section. This medication is used to treat certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine is a psychiatric medication (anti-psychotic type) that works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. Clozapine decreases hallucinations and helps prevent suicide in people who are likely to try to harm themselves. It helps you to think more clearly and positively about yourself, feel less nervous, and take part in everyday life.   FDA Approval Date: 2019-05-20 (Sources: U.S. Centers for Medicare Services, FDA)

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