CLOZARIL Reviews (CLOZAPINE)

Average Rating: 2.8 (59 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

CLOZARIL  (CLOZAPINE):  See also Warning section. This medication is used to treat certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine is a psychiatric medication (anti-psychotic type) that works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. Clozapine decreases hallucinations and helps prevent suicide in people who are likely to try to harm themselves. It helps you to think more clearly and positively about yourself, feel less nervous, and take part in everyday life.   FDA Approval Date: 2019-05-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3


More on CLOZARIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CLOZARILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  bipolar depression super-intense weight gain via surge in appetite 45 mins-1hr later,bed wetting,extremely sedating,and drooling The ONLY reason I gave this med a 5 is because it is the only med in the universe that will put me to sleep.NOTHING else works.I do hate this drug for the side effects,especially the bedwetting and drooling.But what can I do?I need it for survival. The mandatory bloodwork is a major inconveinence and pain in the rump.The 2 good things about it are:no sexual side effects,and good for anxiety. M 12 years
12/13/2008
 2  Schizophrenia Drooling, knocked out straight after taking it  This is meant to be the 'Gold standard' the 'Best' antipsychotic. Did NOT do much for me. PLZ remember everyone responds differently to medication. The thing doctors rarely mention is that Clozaril is one of the hardest drugs to discontinue if you don't like the side effects. It can cause 'rebound psychoses' at its worst. Basically your psychoses can sky rocket off the universe by trying to get off this medication even if your doctor takes you off it slowly. Once on Clozapine you might be on it for the rest of your life coz of what is mentioned above. This can be a miracle drug for some people but for me my paranoia and hallucinations were NOT stopped and were actually worse. I hated the drooling which as far as I know can NOT be stopped by anything. Missing more than 2 doses in a row can make you have a relapse which happened to me. On the up side. This is the only antipsychotic that does NOT cause TD(tardive dyskinesia). If your doing fine on something else don't bother changing hoping for a cure coz at the moment there is NONE.  M 11 months
500 1X day
11/6/2012
 1  Schizophrenia Drooling, drooling This is more sedating than seroquel. Clozaril is the most sedating antipsychotic. Clozaril has the more weight gain than zyprexa. Like the comments before: UR bed when u wake up in the morning will be full of saliva. Yuck! The only way to stop salivating is to tell ur doc to take u off it. I can't get off this stuff keep relapsing and guess what? Doctors put me straight back on it again. My life is a misery and zyprexa actually worked better for me. M 2 years
600 1X day
11/8/2012
 1  Borderline Personality Disorder Sedation, Weight Gain, Apathy, Paranoia I took this medicine for 6 years. During this time, I felt absolutely dead to the world, and miserable. I gained 30 pounds and got scar tissue from the blood draws. I was forced to stay on this medication for far too long, and I cannot think of one positive thing to say about it. I have been off of it for about a year now, and I feel infinitely better. The withdrawal is absolutely terrible (severe headache, -extreme- insomnia, nausea, ect.) but it is definitely worth going through to stop taking the medicine! F 13 6 years
300MG 2X day
1/14/2016
 5  Schizophrenia Extreme sedation, lethargy in the morning, excessive salivating, desire to eat sweets that is impossible to resist, heart races, panic attacks Yes, there are a lot of terrible side effects. Yes, the blood draws are an inconvenience. But clozapine has controlled my schizophrenia better than any med I've been on before (been on lots of antipsychotics) F 19 1.5 years
200 mg 1X day
4/11/2012
 1  Light schizophrenia My son took it for 6 years and his worse of now-totally a vegatable.dont take this drug,its DANGEROUS! M 19 1 days
400mg
4/3/2012
Email
 1  Paranoia Clozaril was taken off the market in the 1960's as a result of deaths from Agranulocytosis. Now patients are tested for this. Plus have to have an ECG at least every 6 months. M 19 10 months
300
12/20/2012
 4  Bipolar 1 Drooling droziness hard to wake up in morning. It's the only medication that stopped the psychosis and helped the voices. Not totally but helped a lot. I'm now able to work and go to school. I'm able to concentrate its was a mirical drug for me. M 21 2 years
375
2/6/2016
 5  To control schizophrenia Drooling. Seizures. The night you take it feel crappy and for awhile in the morning Less suicidal. Helps to get along with others M 22 1 years
550 mg
5/14/2015
 3  Psychosis NOS Drooling, bedwetting (got dose lowered and it stopped) Extreme drowsiness. Paliperidone had no effect so they put me on it. Definitely helped with the psychosis but i hate the sleepiness so much. I mean sleeping 10-16 hours of the day. If i force myself up early im foggy and fall asleep by 630pm. I think im particularly sensitive to this because im on a really low dose so it may be better for others. I hope i can actually come off it in a year or two. F 22 1 years
1X day
5/31/2015
 2  Schizoaffective Disorder Genitals shrinking, spaced out, hard to think, drooling and sweating when sleeping, apathy, craving drugs to feel good, unsociable, weight gain, vivid dreams I hate this med, but im forced to take against my will. I have monthly blood tests and physical reviews by the doctor. M 22 6 months
350mg n
3/27/2017
 5  psychosis sedation, weight gain, memory problems works great on positive psychosis symptoms F 23 1 years
7/17/2004
Email
 5  Schizoaffective/Schizophrenia Drooling at night and Drowsiness and increased appetite Clozaril has made me normal. I have no more symptoms of schizophrenia. I am very happy that I was put on this medication and I plan to stay on it. It is worth the trouble of the weekly blood draws. F 23 6 weeks
200 mg 1X day
3/23/2011
 3  Drug induced psychosis Bed wetting 3x. Drowsiness. Weight gain - up to 110kg now 64kg. Anxiety. Depression. Embarrassment. I was a drug addict from a very young teenager and constantly in trouble. I completed year 9 barely and attempted suicide at 15 with a dose of paracetamol at just about 63000mg. I was very infatuated with drugs, alcohol and my family life was unstable. I was molested as a child by my father 1 time I remember and again by him at 14. I was also raped in a caravan park at that age by a 37 year old man while looking for drugs and alcohol. This shaped me for the next few years into somebody I wouldn't recognise or want to today. I was introduced onto cloz* at 19 and I was and still am compliant. I have done a short tertiary course at university for 8 months, am part time employed as a support worker with a traineeship and hope to do a bachelor of nursing with hopes to work in an emergency department. However I am not getting support because of my achievements and how normal** I appear to be. I have moved forward with my life and grown into a mature responsible adult but I am suffering from anxiety attacks and moderate depression because I guess my past bothers me. I am embarrassed by it. I would like to try another medication. I do not want to be a mental health outpatient for the rest of my life because I haven't had my life yet. I am very driven and I am not where I want to be yet however I am slowly working towards being something I am proud of. I am getting frustrated because I pick up my prescription after a 3 minute chat to the lovely employees at mental health but I am not F 24 4 years
100MG
3/12/2017
Email
 1  Bipolar 1 - Schizoaffective Drooling, sleeping for 24+ hours straight. My daughter taxes Clorzaril and we were very hopeful but no difference in her life than any other drug she tried. Zyprexa, lithium, lamictal, haldol, seroquel etc. She is busy focusing on the voices in her head and doesn't talk much but this has been the ONLY drug she has asked and demanded to stop taking. She hates it but can't tell me why. It does make her sleep alot however and crave sweets. Doc cut her back to 400 mg and added 80 mg of Latuda and also kept her on seroquel in combination. F 24 5 months
650 1X day
4/28/2013
 1  Schizophrenia.....& Psychosis..... It is killing me slowly! I don't even know who I am anymore! I'm so unhappy but a fake smile always fools my doctors and other family members...I've lost all my friends! I shut myself out from the rest of the world. I will end my life soon... death is better than suffering like this for the rest of my life I just hate what this meds have done too me! Even thou I'm now only on 250mg reduced from the high amounts I was taking when I 1st started it. Much love to others whom suffer or feel like the way I do. Keep strong God knows what we are going threw never let others bring you down in life even if its family members...that's happened in my case... M 24 2 years
250mg
5/26/2014
 1  self-injury, bpd drooling, EXTREME weight gain (in institution and not eating much too), drowsiness, not remembering events, bed-wetting, 100% zoned out, taken off because my white blood cell count dropped this is the most EVIL med I have ever taken. My doc wanted to put me back on it saying that, "my white blood cell count didn't drop too far" last time I was on it. Doctors are currently in love with this med, it works for some, but event they have quite bad side effects from what I know. F 25 4 months
1/11/2010
 1  paranoia drooling, knocked me the F out Doctors swear this is the best antipsychotic. It's a big ball of crap. My paranoia and hallucinations were worse. And the drooling was like I waked up with my bed sheets in urine. M 25 2 years
600mg
3/15/2015
 4  Schizoaffective Disorder Extreme drowsiness 1 hour after taking 300mg at bedtime. Very hard to get out of bed with only 6-8 hours of sleep due to the clozapine still in my system. If I have up to 10-12 hours, I wake up okay and feel normal. Do not take huge dosage during the day. You may become very drowsy or even faint. Overall, I noticed a positive change in my behavior, thinking, and outlook on life. I feel stable. M 27 3 years
300 MG 1X day
1/5/2017
Email
 5  Schizophrenia/Psychosis Some drooling Finally, after testing various other medications such as, Seroquel, Zyprexa, Abilify, and and Risperdal. All of these medications didn't help me stop hallucinating(audial). Clozaril, after about a week I was fine and living a normal life again. It's a hassle having to do all the bloodworks, but for me this has been a miracle drug. So it made the bloodworks worth it. After 1 year it is only required once a month(the blood tests). I am free of hallucinations and more focused then any of the other meds I was taking. I give this medication a 5. M 29 1 years
225 MG 2X day
3/19/2013
Email
  

CLOZARIL  (CLOZAPINE):  See also Warning section. This medication is used to treat certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine is a psychiatric medication (anti-psychotic type) that works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. Clozapine decreases hallucinations and helps prevent suicide in people who are likely to try to harm themselves. It helps you to think more clearly and positively about yourself, feel less nervous, and take part in everyday life.   FDA Approval Date: 2019-05-20 (Sources: U.S. Centers for Medicare Services, FDA)

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