LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)

Average Rating: 3.0 (783 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION ANTINEOPLASTICS

 Type: Rx Drug

  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LUPRON DEPOT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LUPRON DEPOTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  endometriosis hot flashes around the time the medication is due again. I have also had memory loss and irritableness which I didn't connect to the med until reading this site and learning it could be a side effect. I just thought I was aging quickly. LOL! I have had endometriosis since before my first period at 11. I have had so much pain with my periods (bed ridden for 3 days), prior to my periods and with ovulating. At the time there was nothing to help. Years later tried Depo Lupron and have now been on it for probably 15+ years. With depo lupron I was finally pain free and it has been amazing for me. Tried to go off of it 1X and the cramps came back unbearably so I am on it again. Note: I have been taking it continuously for 15+ years. I have had a bone density test 1X and it was fine. My memory has been bad and getting worse for about 10 years but never connected it but my family has a history of poor memory too! Any one know of statistics for breast ca or ovarian ca, etc for those taking depo lupron for extended periods? F 44 15 years
9/14/2009
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 5  PROSTATE CANCER HOT FLASHES PSA IS .01 AND LUPRON INJECTIONS HAVE BEEN VERY SUCCESSFUL! M 69 14 years
8/21/2007
 4  Prostate cancer impotence, loss of sex drive, hot flashes, weight gain (30lbs), irritability, dry skin, depression. Well, I am alive. PSA is under relative control, fluctuates from 14 - 18. Sex drive gone, wife probably happy, me I don't know the difference anymore. Weight gain is the worst, getting harder to keep pants up. Problems with knees due to excess weight. Haven't figured out a way to keep off the weight. M 65 5 years
8/9/2005
 3  precousis puberty hot flashes, leg pain, since I have been off Lupron I ache all over, I have had terrible leg pain, major headaches,stomach pain and nausea and I feel bad all of the time, I wish that someone could please explain this to me, my doctor said that she left me on it to long and is not sure what is happening any one that can help? F 14 4 years
10/9/2006
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 4  multifocal breast cancer hot flashes, bone pain, anxiety,very dry skin, dry mouth, dry eyes,injection site inflamation, complete supopression of menstural cycle, difficulty in gait, and a mirad of other symptoms dependent on the time in the shot cycle. The last two shots were the 3 month sort and the symptoms were much worse when compared to the monthly shot. I do not recommend the 11.75 ml shot. Opt for the monthly shot as it is much more tolerable. The doctors do the big shot for convenience...Now I am off the shot my life has returned to a much more normal experience with only slight abdominal symptoms when compared to before the shot. I opted for hormonal intervention rather than the standard chemo offered for my DCIS and invasive breast cancers, stage 2. At 49 I had 2 daughters to raise. Overall it was a better experience than what I witnessed other women go through with chemo. There is no long term heart effects as with Chemo. I recommend this shot on the basis of survival. I wish they had treated me 5 years earlier for the polycystic syndrome, maybe then I could have avoided the cancer assault. Just try to turn it into a chemical Adventure! This shot stopped the terrible menstural syndrom I suffered with for 8 years. 54 3.5 years
7/28/2007
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 5  Severe Endo Hot flashes, Mood Swings, head aches I have been on Lupron for about three years now. This to me is a WONDER DRUG. I was in so much pain before this I had my appendix burst and thought it was the endo. The bleeding was so bad I would pass out from blood loss. Now I can do what ever I want when I want.My endo is controlled and am now getting ready to try IVF. I would never had made it this long with out Lupron. (I know I sound like an ad for the med - but it's true.) The side affects where tough to get use to. But the pain I was in was unbearable, headaches are nothing compare to what I was feeling and the hot flashes are very rare. F 29 3 years
3/28/2007
 5  Prostate Cancer Hair loss from legs, arms, chest, Hot flashes, Middle weight gain, Reduced enegery level, Tired feeling a lot of the time,Loss of sex drive, Loss of sex intrest, Headaches, A lot of heavy phlegm. I was diagnosed with Prostate cancer at age 67. I had a PSA every 6 months for 15 years. In Jan of 2002 the good PSA was 24 and the bad PSA was 3.5. The bad had been runnning from 3-4 for 3 years. In June of 2002 the good PSA was 18 and the bad PSA was 4.75. At that point the Urologist scheduled a Biopsy and the cancer was found in 4 of 5 samples. I was lucky sometines it is missed. My "Gleason" number was 8.5. I received the first 4 month Lupron shot in February 2002 to try to stop the cancer and shrink the Prostate. I underwent radical Prostate surgery in April 2002 and there were no cancer cells outside of the Prostate. They checked Lymph nodes and they were clear. Because of the high "Gleason" number I stayed on 4 month Lupron shots, receiving the last one in June 2006. My PSA has been lower than they can read since the surgery. It is now <.04. I took Megace "Megestrol" from June 2002 untill April 2006 for the Hot Flashes, it controlled them. Before M 71 3 years
6/22/2006
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 4  PROSTATE CANCER HOT FLASHES,BONE PAIN. WEAKNESS. LOW SEX DRIVE IF WILL HELP KEPT BE ALIVE I CONTINUE TO TAKE IT. M 63 3 years
5/16/2004
 4  Breast Cancer Hot flashes, weight gain, dry skin, bone pain, joint pain, I am also on Tamoxifen, if this is what it takes to save my life, then I am quite content to be on it. F 48 3 years
10/21/2004
 4  prostate cancer Hot Flashes, Fatigue, Dependency(ie: when I am near the end of my 4 month cycle, my side effects are worse.) Neck & back pain, impotency(complete) Hot flashes. I feel terrible all over. Injection every 4 months. My doctor tells me it is up to me as to when I may stop the injections. Most take for only 3-5 years and if the cancer comes back...what then? Maybe some other treatments may work. I would like to know more about tistical removal. Seems to make more sense to me. M 49 3 years
2/7/2005
 4  endo hot flashes, decreased libido My Dr. put me on lupron in hopes of decreasing further damage. Found the endometriosis during an exploratory laproscopy and he doesn't want to go back in until Im ready to have kids (at this rate who knows when that will be!) Been on Lupron since we found it at the age of 18 and have been on it since. Side effects have been minimal. Main perk: no painful mentrations in years! In other words, I like the drug. F 21 3 years
9/28/2007
 1  Contraception Horrid feelings. Night sweats, paranoia, nervous, anxious. Got studpid feelings about my boyfriend being with other women even though I know he woulndt. DONT EVER TAKE THIS INJECTION. NEVER EVER HAVE THIS STAB. I have only worked out today that this had made me feel so bad. It explains a whole heap of crap that has gone on in my life. F 31 3 years
3/10/2007
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 4  Endometriosis Hot Flashes, extreme weight gain with inability to loose any weight, depression, anxiety Even with the side effects, I would prefer dealing with them more than the 14 years of agony I went through before I was diagnosed and put on the lupron therapy. After almost three years on the shots, I will still go religiously every 12 weeks for the shot until I decide to try to conceive. The first three months of the shots are the worst. After that you are so used to everything that the side effects don't seem that bad anymore. F 26 2.75 years
10/28/2005
 5  had partial hysterectomy-endo / lack in sex drive- hot flashes -but I take hormones so I don't have those.. bloating for three days after I have shot.. I had a partial hysterectomy but because I was only 27yrs he wanted to keep my ovaries- After 5 mths of bad swelling of my left side and very bad yeast infections the week before (when my period use to be.) The doctor put me on lupron and all of the swelling and infections went away.. I love this med. it has allowed me to live again after 7mths of Hell --- I can only be on it for 3years(almost there) then I'll have to go and get my ovaries removed --which is scary since last time it took so long for me to feel better. If anyone reads this and has any suggestions please e-mail me at [email protected] Thanks F 30 2.5 years
11/29/2005
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 4  advanced prostate cancer bone mets Fatigue, hot flashes, arthritis, loss of balance, depression, enlarged breasts and weight gain.Still work full time but with a flexible schedule. PSA 0.2 Cancer is stable with no additional metastasis. M 57 2.5 years
7/18/2005
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 5  Hemmorhaging From Fibroids Hot flashes and sweating. Bone pain first 3 months, none thereafter. I was somewhat "wired" from the Lupron also. I took calcium, magnesium, and vitamin D every night faithfully. I also took 5 mg. daily Provera. F 50 2 years
11/8/2005
 5  central precocious puberty Minor pain at site of injection Very effective, put off menstruation for a couple years until I was ready. Slowed me down so that my peers could catch up physically and I didn't feel like such an outcast. Note: was on medication from ages 9-11 F 16 2 years
1X M
8/22/2011
 5  Fibroid tumors Hot flahes, weight gain, Not sure about headaches I've always had them, but now I have them in my sleep. Saved my job..changed my schedule at work and I now have to be there. I would have lost my job if I had not received that shot. This is March,12 I had my last period March,11 and I could not move. Bleed for 36 hours straight!! OMG what a nightmare. I had just come off of lupron for the second time. I didn't know I could not stop getting the shot since it says 6 months. Figure it didn't work the 1st time, so i got it again. Behind that nightmare 1 year ago. I have not been w/out the shot until now. Couldn't get it this month and I am having all those horrible symptoms again. I pray missing this month doesn't make me have a cycle again. I love Lupron, whatever the side effects, doesn't compare to the pain, headaches and horrible flow. I also read reviews of Lupron and started not to get it. Even after the 2nd round, I read the reviews again and hesitated.-musta been crazy! I got the shot in 4 6month doses. It helped me soooooo much. Because of all the bad reviews I chose the lower 3.75 dosages, maybe the high dosage makes side effects worse. I wanted to ease into the medicine, to try to feel out side effects and stop if I needed to. F 51 2 years
3.75 1X M
3/30/2012
Email
 5  prostate cancer Tiredness and bowel problems but this may be due to old age. PSA reading shot up to high twenties and an operation was considered but I chose the Lupron injection treatment every 3 months. 'Something else will probably kill you first' was one bit of advice. My latest PSA reading was under 2 so I am pleased with the results so far. M 81 2 years
7/24/2009
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 4  severe endometriosis pain in joints, headaches, mood swings, slight weight gain According to my OBGYN & Oncologist that performed a hysterectomy on me, I will be on Lupron for life. I was told by the Oncologist that I had the worst case of endometriosis that he's ever seen. The endometriosis cemented itself to my entire abdominal area & made a wall between my lower & uppper body. Doctor's are unable to remove it. I lost my right kidney due to this and was in severe pain (screaming at top of my lungs)before the surgery. I've been taking lupron shots for over 2 years now and I am completely pain free. I am very tired of taking the shots, but very thankful to God that I don't have to go through the pain that I had before. It was like hell on Earth. F 41 2 years
12/19/2007
  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

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