LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)

Average Rating: 3.0 (783 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION ANTINEOPLASTICS

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LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on LUPRON DEPOT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LUPRON DEPOTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Fibroids Headaches(severe), facial pain/swelling, TMJ/ Trigeminal Neuralgia/ hypertensive Crisis/ Joint Pain /Insomnia, Anxiety/depression. Suicidal Ideations (Mainly because of how miserable this drug has made my life). Q I was diagnosed with Fibroids Sept 2023. It was recommended due to the larger being in my upper right quadrant. It would be beneficial to shrink the fibroids using chemical induced menopause (they make it sound so easy). Three months on they managed to spare me a large vertical incision but am left scared to death what is going on with my body. My doctor suspects TMJ (never had this before the shots). I have spent most of my time in bed. I have been to A&E with hypertensive crisis as a result was given an ecg (QT Prolongation and abnormal T and S waves). Am now waiting on a Echocardiogram and a visit to a Neurology Clinic. I sympathise with all of you who have been through the stress and upset this drug has caused. Without a doubt it is life changing for those who unfortunate enough to experience the more severe side effects. Can only plod on and try to carry on. Its been so distressing I can’t put it into words. I know for some its been a positive drug and helped in extreme debilitating circumstances. However without a doubt it should be only administered when a thorough indication of the risks are advised. I would not recommend this drug to anyone unless it is a last resort. F 43 3 months
1X M
3/29/2023
Email
 1  Breast cancer Briefly? Lol. Athlete to being on disability. Debilitating bone and muscle pain, hair loss, tooth and bone loss. Chronic UTI; severe accelerated DDD and DJD; central obesity, 100# weight gain; severe short term memory loss; inability to retain or memorize the simplest things; tachycardia; Lupron accelerates the aging process overnight by approximately 25 yrs. Don't believe me? I dare u to take one shot. My problems only got worse, nothing improved. F 50 5 days
Varied 5X M
6/19/2021
 1  recurring prostate cancer insomnia leg pain 20 lb weight gain in mid section grew breast testicals shrank memory and cognitive decline head aches unbeliveable fatigue muscle loss hot flashes ears ringing no sex drive very emotional crying suicidal thoughts loose stool six times a day I was not told about the side effects or given anything to read blood pressure went up 20 points also It was like being on a plane about to crash and pilot didnt say brace for impact there was no monitoring during the six months I was on it I would never take again rather die M 61 6 months
? 1X O
3/16/2021
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 1  adjuvant Rx Stage II prostate ca RT Within a week severe palmar tingling, flexor contractures and bilat carpal tunnel and trigger fingers Sx reached their peak about 6 weeks. Surgery at 7 month, open carpal tunnel trigger finger release but tenosynovitis swelling/contractures continue despite surgery and months of topical testosterone tried as antidote M 75 6 months
45 mg
10/6/2020
Email
 1  silent endometriosis, infertility Horrible hot flashes, irritability, but worse, awful disabling pain down my arms from the shoulder to elbow: bicep tendonitis F 33 3 months
11.25mg
12/29/2019
Email
 1  To induce menopause Muscular pain in my legs Painful intercourse Arthritic pain in my hands The muscular pain in my legs lasted 6 days and was constant, day and night. Two days after exercise, a sore muscle turned into strong pain in my shoulder for a week. Intercourse was extremely painful for a week (could not have sex). Moderately painful for 3 weeks. Arthritic pain in my hands every morning F 54 5 months
7mg inject
12/26/2019
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 1  pre-surgery I had horrific panic attacks and blurry vision in one eye. I only did 2 of the recommended 3 injections. My panic attacks lasted for over 20 years. I have to manage them with Xanax. Do Not Take This Drug. F 52 2 months
1X M
9/29/2019
Email
 1  Prevent endometriosis Body pain , insomia , hair loss, migrane,depression,neck pain, palpitations This drug should be out ! F 40 1 months
3/25/2018
Email
 1  Endometriosis Never ending side effects. I had this drug injected in me with hopes it would stop Endometriosis spreading. It caused me to eventually have to give up my career as a child psychologist to being totally disabled with Endometriosis growths and fibromyalgia, RA, muscle spasms and ptsd. It never leaves your system and attaches to your dna and changes it. I miscarried at 16 weeks after my last injection 4 months before I was pregnant. I’ve never been pregnant since then in 1995. I am now on stron pain meds just to function and spend many days in bed. Do not take this drug poison under any circumstances. It will ruin your health for life and not cure what the docs say. They get paid off to prescribe it by big pharma. Do not take this medicine!! It’s pure poison. F 49 6 months
150mg shot
2/20/2018
Email
 1  Uterine Fibroids Hot flashes, cramping, nausea, severe abdominal pain, migraines, insomnia, mood swings I did not listen to the warnings of those who got the shot. I'be been regretting my decision for the past 2 months. I had zero side affects for the first 3 weeks. Then came the hot flashes, migraines, and mood swings. But wait, it doesn't stop there. If I was working while on this medicine, I would not be able to do my job. The severe abdominal pain and nausea didn't come until the end of the 2nd month. I am in a constant state of sickness and cannot leave the house. To top it all off, my fibroid did not shrink or change, as I was promised. Now I am miserable for nothing. Please, please, take my warning and do not take this medicine. It will dramatically impact your daily living and not bring you results. F 28 3 months
7/30/2017
 1  prostate cancer brutal hot spells bad taste in mouth no energy swelled legs anxiety jitters depression strange smells memory loss I feel absolutely awful,no information about side effects given,doc does not seem to care.I would appreciate comments from men about similar side effects or women who use lupron.This stuff is awful,I am also a hypochondriac I suffer health anxiety so each symptom worries me.I would not recommend using it but what else can we do? M 70 9 months
13.5 mg 3X M
6/18/2017
Email
 1  To prep for hysterectomy Sick to my stomach the whole time, nausea, panic attacks, anxiety,depression, hot flush, cold sweat, blurry vision, lost appetite, back pain, I DO NOT RECOMMEND IT TO ANYONE This has been the worst 3 months of my life, my gynecologist recommended this poison 3 months ago due to my anemia and fibroids, well let me tell you that didn't work 2 weeks after I have lupron, I had an emergency hysterectomy because I was losing to much blood. First I was happy that finally I had the surgery then I realized that I still have lupron on my system for anothe 2 months and a half.. it has been so difficult, this side effects are not joke... when they tells you the you might get this side effects IT MEANS "you will get it for sure" I'm over the 3 months now and I still have this side effects .. can't wait to be normal again. I haven't worked all this 3 months due to all this side effects Please please please don't do lupron ask your doctor for more opcion, this medicine is a killer F 45 3 months
11.25
5/28/2017
 1  Endometriosis All the common "temporary" side effects of menopause; plus some I was only life-threatening allergic reaction the year following treatment. My autoimmune system went wacky. Heart issues, nerve damage, I began passing out from hypothyroidism. Years later I was dx; with a thyroid goiter.and a brain aneurysm.Too many other Dx to list. Please do not use Leuprolide Acete / Lupron Depot! You may not get to live long enough to regrete it. They "Lied by Omission" Left out important information like it is an ".Antineplastic that kills "Healthy Cells as well as Cancerous Cells". They also said all side-effects are temporary. LIE!, LIE!, LIE, I was only 32. Why has the FDA not restricted this drug for Cancer patients only??? Another Thing For President Trump to Make Right... F 54 6 months
3.75 1X M
3/13/2017
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 1  Endometriosis TERRIBLE HOT FLASHES. JUST TERRIBLE. Always moody. It didn't stop my period my first month, I came on as scheduled, but missed the next shot, as they were monthly, but yet haven't had a period since.. Im not looking forward to another dose. DON'T DO IT F 25 1 months
3.75
1/11/2017
Email
 1  Endometriosis Night sweats, severe cramping in ovaries, nausea, neck and back pain After coming off depo provera, I had the worst period of my life. Going on 6 weeks now (still heavy bleeding & severe uncontrollable pain), & I've been on lupron for about 2 weeks to shut down everything. So far, it's been a nightmare... My pain is SO bad, even 10mg of percocet with 800mg of ibuprofen doesn't touch it. Hoping it will get better, because I can't take much more of this crap. F 24 1 months
3.75
11/27/2016
 1  Fibroids I've had severe body aches. Constant nausea and vomiting. I had a 3 month dose in May. The hot flashes have been awful. I seem to be having more symptoms in the 3rd month. The upside, the bleeding stopped. But the side effects are unbearable. I will never take the shot again and I don't recommend it. F 41 3 months
8/8/2016
Email
 1  Endometriosis Miscarriages Oh well I got dizzy I couldn't see I couldn't hear the buzz he might hearing when my Joles deteriorating my house Extreme bone pain and joint pain in my greens and I'm sleepy and I'm mad all the time in my cramps are like contractions now and my back hurts and my feet hurt and feels like my something is eating my insides my ribs feel broken just absolutely brain numbing pain I can't get rid of it I thought it was just arthritis for a long time and then recently went to the doctor again talking about maybe doing laparoscopic surgery hysterectomy and told her about the Lupron and then I got to researching and then I found that the 300,000 people at the exact same problems and almonds bolting died do not use that shot it does the opposite of helping us my doctor promised it was FDA approved several times it was the best thing ever all the other girls are very excited and they're having babies and oh yay so 27 years old I'm Ginna get to have a baby finally does seven miscarriages I have one son I mean it's just been shitty and now I'm from 27 to 35 my eyesight horrible like I can't see at night and I cry all the time and I'm tired and my legs hurt so bad I can't walk in I'm just unhappy and healthy mad they when ahead and use their own darn labels and then the doctors charge what they wanted I paid $1000 a month and my memories of really bad so I think it was the 90 does that really remember and I think it was six months but I ended up having my surgeries in between is on all k when ahead and use their own darn labels and then the doctors charge what they wanted I paid $1000 a month and my memories of really bad so I think it was the 90 does that really remember and I think it was six months but I en is on all kinds of pain pills and it's been a mess F 35 1 months
90
3/5/2016
Email
 1  tiny fibroid I had heavy periods but only a tiny fibroid on the OUTSIDE of my uterus. I had a failed balloon ablation, then they moved to 3 shots of Lupron, that over shrunk my uterus. I ended up having Hashimotos thyroiditis, so I was misdiagnosed. The worst HOT FLASHES x 100 for 6 months, jittery, moody, hormonal rage, over shrunk uterus has remained, 10 years later. I cannot get a pap smear anymore. It shrunk up like a prune. I was told if I start to bleed, even a drop, they will remove my uterus. DO THYROID TESTING. Ruining my uterus was unnecessary, and now I am at a higher risk of uterine cancer! I ended up demanding they TSH TEST! Two OBGYN's missed this completely. One was a specialist. It is a cancer medication and I do not think it should be used for fibroids. (mine was tiny and it was on the outside of my uterus) Being thrown into early menopause because I had Hashimotos, was beyond deviating in the standard of care. Blood tests are not as invasive as balloon oblation and (3) shots of LUPRON. MY OBGYN cannot preform a pap smear on me ANYMORE. She said "it is like cobwebs inside. The walls are all stuck together". Not a cure for Hashimotos thyroiditis by any means! F 55 3 weeks
3X M
7/14/2015
Email
 1  fibroid tumors I feel like my life is over i was 57 yr old when i took this drug,should have done my research first but i didn't. I cant sleep,cant remember anything,depressed so bad i dont want to leave my house,anxiety,mood swing,heart attack,back pain,joint aches,hot flashes,lost sight in both my eyes,every year it something new it doesn't get any better but worst. This drug needs to be taken off the market right now before it destroys anymore lives. I advertise no one to use this poison it's horrible F 60 3 months
30 mg
6/12/2015
Email
 1  fibroids heavy bleeding Took one dose on 1/21/15 and have had progresive joint muscle and bone pain to the point can hardly walk anymore ..my feet burn joints constantly ache even when lying down my scrum painful when i get up from a sitting position horrible drug..night sweats...i cant hardly walk this is upsetting the stay away from lupron F 41 1 times
5/27/2015
Email
  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

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