LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)

Average Rating: 3.0 (783 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION ANTINEOPLASTICS

 Type: Rx Drug

  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction highest to lowest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LUPRON DEPOT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LUPRON DEPOTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Uterine fibroid None I was so freaked out about getting the 3-month depot shot but it turned out to be no big deal. I have lost a bit of weight, my hair has stopped falling out, I have more energy and I haven’t noticed any muscle or joint pain aside from the typical aches and pains I deal with anyway. F 40 12 weeks
11.25
5/7/2018
 5  endometriosis my endometriosis symptoms went away almost immediately. I have had little to no side effects. A little bit of fatigue that I think may be attributable to it because I can't think of any other reason I've been a little bit tired. F 42 2 months
6/11/2015
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 5  fibroids None so far. I did have minor muscle ache in my upper left arm but it was nothing serious. No hot flashes, mood swings and etc. I am taking the add back though. Took it the first day I got the shot. So I hope that's what's controlling menopausal symptoms because I feel great. Due to my large fibroids I am taking lupron + add back to hopefully help shrink my fibroids. I couldn't wait to get my first shot due to my heavy bleeding. I take the 1x a month. Dr wants me on for 6 mos max. May be less if fibroids shrink enough for myomectomy. Period did come first month, and 2nd shot did come next day but was only spotting. Just got the 2nd shot around 2wks ago. Dr said its normal due to body has to get used to it. I am very happy so far. Don't feed into all the negative feedback. We are all different and I wish you the best. F 40 2 months
3.75
5/3/2015
 5  Endometriosis Minor hot flashes (actually welcome during cold winter!), BAD headaches 2-3x/month, achy joints- esp feet & legs, minor mood swings, weight gain (holidays didn't help!), brain-fog/forgetfulness, but most natably, NO PAIN FROM ENDOMETRIOSIS! Though a different dosage, I took Lupron many times from 1998-2007 for IVF. I have 4 children of my own & also 2 surro-babies :-) I don't recall any major side effects then. This time around is different! I am experiencing increased joint/muscle pain-esp in my legs-and found this site looking for answers. There are some pretty scary posts here! Though I have some serious side effects, I am assuming they will resolve once my 6-month treatment ends. They are all worth not having the pain of endometriosis every month! I have been thinking that gluten is making these symptoms worse, so am not entirely convinced that Lupron is the cause. F 42 4 months
11.25
4/5/2015
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 5  fibroids hot flashes. Fibroids and bloating greatly (although temporarily, I understand) reduced. Period stopped; no spotting. AWESOME stuff! F 47 6 months
3.75 1X M
3/11/2015
 5  Endometriosis Hot Flashes, Night Sweats, Mood Swings, Fog As bad as the menopausal symptoms are it greatly helped the pain F 24 1 years
3.75 mg
1/31/2015
Email
 5  hospital none of them it helped me alot no pains nothing cz every month i was in pain thank god and the doctor F 30 1 months
30by2
1/27/2015
Email
 5  fibroids Night sweats. I had a fibroids measuring 5cm. After 2 days of my first shot. Too mach bleeding then my hgb drop to 7.no problem at all before that I'm taking ferrous n continue it. Then I go for ultra sound it measures 4.4cm. On my second shot the fibroids becomes 2.2cm. Done my 3 shots n the fibroids still degenarating. No heavy menstral period at all. During the medication I indulge my self in gym. Do my work out 3 times a week.watch my diet high in fruits n vegetables my soul source of protein was dairy products.no red meat at all.1 liter of water/day. Lupron depot affects our hormones..so a great suggestion is have a physical work out n healthy diet will help the patient to prevent the drastic side effect of the medication. Healthy lifestyle together with medication n prayer..positive results. F 38 3 months
10/16/2014
 5  Uterine fibroids None. F 37 2 months
3.75
3/17/2014
 5  Endometriosis NIght sweats, hot flashes, vaginal dryness, forgetfulness OK ladies this is my second time taking Lupron within 3 years. After my surgery to remove a ovarian tumor in October 2009 when I went to my post-op appointment is when I was told that I have Endometriosis. I started Lupron right away. The pain was instantly gone and so were my periods. Life was great! Then in September 2011 I went for my annual pap and was discussing with my new GYN that I wanted to get pregnant. I had been preiviosly married for 14 years and never once did I get pregnant. Now I know for sure that the problem was me (my ex cheated and got her pregnant). Now I'm engaged to my childhood friend who is my soulmate and now I want to have a baby with him. So after I had an ultrasound done it was confirmed that I did have another cyst and that he wanted to see how bad my endo was now.(I had pics from my previous surgery). Once my new GYN saw the pics he said he could only imagine how bad it would be since the pics were over 2 years old. Long story short I had surgery in December 2011. all went well. My Endometriosis was like a spider web covering all my reproductive organs. My doctor was sucessful in removing it. Unfortunately I lost my left tube because it is completely blocked and my uterus was attached to my abdominal wall. He detached my uterus and left it in. I am going for my final shot in this round tomorrow. this will be number 12 that I've taken since 2009.Next friday 6/29/12 I will be discussing what my next step will be to try to become pregnant. I know F 35 6 months
3.75 1X M
6/21/2012
 5  Endometriosis Severe hot flashes, mood swings, no decrease in sex drive but very dry. I'm now 22 and getting ready to have surgery and do another round of this. Honestly it was the best 6 months of my life to have such a relief from pain. F 18 6 months
1x/month
4/27/2012
Email
 5  Fibroid tumors Hot flahes, weight gain, Not sure about headaches I've always had them, but now I have them in my sleep. Saved my job..changed my schedule at work and I now have to be there. I would have lost my job if I had not received that shot. This is March,12 I had my last period March,11 and I could not move. Bleed for 36 hours straight!! OMG what a nightmare. I had just come off of lupron for the second time. I didn't know I could not stop getting the shot since it says 6 months. Figure it didn't work the 1st time, so i got it again. Behind that nightmare 1 year ago. I have not been w/out the shot until now. Couldn't get it this month and I am having all those horrible symptoms again. I pray missing this month doesn't make me have a cycle again. I love Lupron, whatever the side effects, doesn't compare to the pain, headaches and horrible flow. I also read reviews of Lupron and started not to get it. Even after the 2nd round, I read the reviews again and hesitated.-musta been crazy! I got the shot in 4 6month doses. It helped me soooooo much. Because of all the bad reviews I chose the lower 3.75 dosages, maybe the high dosage makes side effects worse. I wanted to ease into the medicine, to try to feel out side effects and stop if I needed to. F 51 2 years
3.75 1X M
3/30/2012
Email
 5  Stage 4 Endometriosis, infertility Mild heartburn for 3 days following my first injection. Mild hot flashes started after my 2nd injection which continued to increase in frequency and intensity. The hot flashes increased following my 3rd injection with night sweats, some insomnia, and some slight changes in irritability. My weight has remained stable and I haven't had problems with acne. I started Lupron Depot 1x/month inj immediately following lap surgery to remove stage 4 endo. My doc's goal was to put me on this med for 3 months to stop estrogen production to allow my body the chance to heal. I had my 3rd injection 3 weeks ago and will be seeing my doctor again next week to discuss the next step towards pursuing IVF. I'm fortunate because I never suffered w/ pain from my endo even though it had bound my organs together resulting in infertility and causing a kink in my bowel. Since starting Lupron, I've had some mild discomfort but nothing intolerable. The hot flashes feel like standing in front of a 400 degree oven when you first open the oven door, but they go away eventually. The night sweats are a nuisance, but I've been able to fall back asleep. I feel irritable at times, but honestly, I made the personal choice to accept that these symptoms are only temporary & this has allowed me to continue living my life without ruminating on how much it sucks to be infertile, to have endo, to have hot flashes as a 34-year old, etc. Remember that the majority of people who write blog entries are going to report their negative symptoms, while the people who don't have the side effects aren't even looking on the internet in the first place. I wanted to put my honest opinion out there to counteract the negative feedback. My heart goes out to anyone who has suffered from this medication. I wish you all the best of luck with your health and fertility:-) F 34 3 months
1X M
12/16/2011
Email
 5  Endometriosis, pain Headaches, fatigue, hot flashes, night sweats, weight gain I just finished my 6 month treatment (1 shot/mo) of Lupron with the last shot being one month ago. I read a LOT of horror stories online prior to taking the drug, but decided that personally, I needed to try it because the benefits could have out weighed the side effects. For me, that was a smart decision. I was in such severe pain. I was on continuous birth control, I had surgery, I took narcotic pain meds, I had cystoscopies and was on the IC diet for months. To say the least, I had investigated other options. I will not down-play the side effects. They are not pleasant. But compared to what I was living with, they are a walk in the park. If you are having mild discomfort and pain from endo, or other issues, think twice before taking this drug. The side effects will probably seem horrific if that is the case. But for me, I will take all those side effects and an extra 30 lbs over the pain and disruption endo was causing in my life. It may be short lived now that the shots are over, but I would do it again if needed and if it will mean keeping all of my organs necessary to conceive. My doctor was thorough in explaining my choices, and I made an informed one. I suggest you do the same for your own situation. F 28 6 months
3.5 1X M
11/22/2011
Email
 5  central precocious puberty Minor pain at site of injection Very effective, put off menstruation for a couple years until I was ready. Slowed me down so that my peers could catch up physically and I didn't feel like such an outcast. Note: was on medication from ages 9-11 F 16 2 years
1X M
8/22/2011
 5  Large fibroids, anemia, pre-surgery Hot flashes, very slight discharge monthly. Excellent product that is doing everything my doc said it would do! Rating is now a 5! F 47 4 months
11.75 mg 1X day
7/27/2011
Email

Patient History
 5  Endometriosis insomnia, small weight gain, about 1 hot flash a day-if that. So glad I trusted my doctor about taking this! I suffered with absolutely horrible pain for almost a year. Had surgery, found endometriosis, then was put on the Lupron injections and also Aygestin to minimize the hotflashes, etc. I have had 4 injections, I have been pain free since after the first 2 weeks of the 1st shot! I will take the tossing and turning at night and a little weight gain to be pain free! It's just wonderful! F 28 6 months
1X M
7/20/2011
Email
 5  Excessive bleeding Hair growth...i normally shaved my legs 1 time per week having to shave daily now. Also noticed faster growth on heaf cause my roots are about one quarter of inch showing F 37 2 weeks
1X day
6/24/2011
 5  Endometriosis some weight gain, hot flashes & night sweats I read a lot of negative reviews about lupron, but decided to trust my doctor. I'm so glad I did! I've been on lupron for 3 months now and have been pain free ever since. I had 1 episode of break-through bleeding when I first started, but that is typical I'm told. I've had night sweats and hot flashes, but those have tapered off. I have gained some weight, but for me, being able to go pain free is worth the trade off. F 26 3 months
1X M
5/25/2011
 5  Severe Endometriosis Hot flushes (ie when a little warm will become very so/sweat); occasional nightmares (I believe associated with Aygestin) Extremely positive experience. After a laparoscopy to remove an ovarian cyst, part of an ovary, and severe/widespread endometrosis growths, I am taking Lupron shots 1 every 3 mos for 9 mos. I was in chronic pain with the untreated endo, had no energy, and gained 30lbs in a year. Since the surgery + Lupron + Aygestin I have my life back; energy, no pain (with the exception of some cramping around the time of what would have been my first period, but not as bad as before treatment), and minimal side effects. I have lost weight because I've returned to a moderate exercise regimen that I was unable to do when in so much pain from the endo. I follow a fairly strict menopausal diet (including restricting alcohol intake) that I think works well to reduce the hotflashes, prevent weight gain, and hopefully prevent osteoporosis/loss of bone mass. Physician recommended Black Cohosh and Slow Mag for hot flashes, and I haven't experienced any. FYI, my physician suggested taking Aygestin earlier in the day if the side effect of violent nightmares is being experienced. F 41 80 days
1 Inj/3mos 1X O
2/17/2011
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LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

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