LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)Average Rating: 3.0 (783 Ratings)Filter ResultsCompare LUPRON DEPOT with similar:
Type: Rx Drug
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Results are sorted by Age oldest to youngest. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 |
More on LUPRON DEPOT: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR LUPRON DEPOT | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | prostate cancer | Temp: hot sweat Permanent: Low back ache, weak legs, unsteady gait, tire easy. | I was on lupron for 1 1/2 years. The adverse reaction was so bad I sought a second opinion. The second urologist took me off all medication. My prostate has never bothered me and I havebeen off lupron for 1 1/2 years. | M | 85 | 1 years | 11/14/2004 | 1 | prostate cancer | Enlarged breasts. Weak lower extremities, low back ache, loss of torso hair, unsteady gait, shrunken penis, loss of energy. | Bad news for me. | M | 85 | 1.5 years | 1/9/2005 | 4 | prostate cancer, bone metastasis | Osteoporosis, hot flashes, skin reaction (Eczyma), sex change: (impotence, grow belly and breasts, atrophy elsewhere) | Sommer 2007: Severe back pain. Prostate cancer was discovered, PSA over 500. It was in by bones, the fouth vertebrae. 11 radiations got rid of pain, but was too strong, closed my troat, could not speak, could not eat, lost 20 lbs in a week, almost died (got bill anyway), Recovered. (doctors prescribed mouth wash, did not help, my wife broke up Aloe Vera jells and fed them down my thoat, it gradually opened my throat). Since then getting LUPRON DEPOT injections first monthly, then every 3-4 months. PSA December 2008=0.85. Great. But side effects are bothersome. Will suggest skipping one injection, to see what PSA does. Only if it goes up again will I ask for another injection. Also will do another bone density test, which will show the osteoporosis or not. maybe I beat the cancer yet. | M | 83 | 15 months | 12/9/2008 | 1 | Prostate | My dads urologist administered Lupron Depot . My dad had prostate cancer 20 years ago and his PSA level was slightly elevated in October. His urologist never warned us of the side effects an elderly person might encounter on Lupron Depot so we were in complete shock when dad suffered a major stroke. We are very upset ... Dad was very healthy for an 83 year old, going to aerobics class 3 times a week..now he can't walk or use his left side at all and he is confined to bed. If we would of known that this drug caused strokes, we would of never agreed to use it! | M | 83 | 1X day | 3/2/2014 | 3 | PROSTATE CANCER | AT BEGINNIG HOT FLASHES THAT ALMOST QUIT AFTER 6 MOS, OR SO. TIREDNESS TOO OFTEN, DAYS I HAVE THE JITTERS FEELING INTERNAL NERVOUSNESS,COUGHING SPELLS,DRY MOUTH, BAD TASTE IN MOUTH,WATERY EYES & AT TIMES DRY EYES,OCCATIONAL ACHES & PAINS TOO MANY DAYS FEELING OF GO TO HELL ATTITUDE.MY OVER ALL GENERAL HEALTH HAS DETERIORATED THE PAST TWO YEARS.I'VE KEPT RECORDS THE PAST FOUR YEARS OR SO. | SINCE IT DOESN'T CURE THE PROBLEM I'M CURIOUS ABOUT OTHER TREATMENT THAT MAY CURE IT. RATING SATISFACTION AT THIS TIME IS DIFFICULT BECAUSE OF MORE INJECTIONS IN THE FUTURE.*** | M | 82 | 9 days | 6/24/2005 | 2 | Prostate Cancer | Not enough room. You name it, I got it. | Ruined my life, cancer gone but one Oncologist said radiation would have been enough for me, maybe 1 Lupron shot. 2006 Cancer treatment included Lupron, but nobody knew about side effects. Now after results they try not to give it. 2 months after 1st shot I was in bed for 2-3 weeks. Too weak to answer phone or change tv with remote. 50% of my former energy, but worse it affected my brain also. Brain fog, but worse I have never for 1 day In 17 years felt good or the same as I did for 65 years. Do not let Dr. pat you on shoulder and say “you’ll be fine”. Female hormones Are for females, not men. 3 years ago for no reason I got worse and down to 20% energy if that. Bed 22 hrs a day, but I’m old and retired. I feel ok in bed, but lousy up. Still spinning head. Just don’t take it unless Dr. ( and get 2cd opinion) says it’s s fatal. | M | 82 | 1 years 3X O | 11/3/2023 | 5 | prostate cancer | Tiredness and bowel problems but this may be due to old age. | PSA reading shot up to high twenties and an operation was considered but I chose the Lupron injection treatment every 3 months. 'Something else will probably kill you first' was one bit of advice. My latest PSA reading was under 2 so I am pleased with the results so far. | M | 81 | 2 years | 7/24/2009 | 5 | prostate cancer | Loss of libido. Diminished size of testicles. No hot flashes. No weight gain. No muscle weakness. Continued all excercise regimins of resistance and biking and started swimming lessons at 4 months into Lupron. I even increased the weights on resistance machines. | After reading the comments of others, I was dreading starting Lupron/Depot but other than the two listed side effects, my life has continued exactly as before including all exercise programs which average about an hour a day. Also had 38 radiation treatments on Varian Associates Trilogy machine during this time. | M | 80 | 5 days | 5/2/2007 | 5 | prostate cancer | my last rating recorded 5 days and it has been 5 months since I started Lupron | M | 80 | 5 months | 5/2/2007 | 4 | ProstateCancer | Hot Flashes. Total loss of libido. Unable to get eractions | Been on Lupron for 5 months. Second shot hurt so bad could hardly walk for 3 days. PSA went from 38 down to 2.4 so it is working. Going to go intermittent to give body a chance to recover. Trying to keep from surgery/radiation if possible. | M | 79 | 5 months | 12/23/2009 | 4 | prostate cancer stage 4 | The most disturbing side effect has been that Lupron has caused inflammation(feels like heart burn) in my stomach and small bowels. As a result I want to soothe the burning by eating all the time. My waist size has gone up two inches and my weight by twenty pounds over the period of a year. The standard medication of heart burn (tums, zantac, etc.) does help to ease the burning in my stomach but not in the small bowels. | Lupron has lowered my PSA to 0.0 and effectively supressed any libido which at my age (76) is something I can live with. I would be an enthusiastic user but for the heartburn and weight gain. | M | 76 | 12 months | 7/18/2007 | 4 | High PSA reading | Hot flashes | PSA reading dropped from 35.8 to 0.2 | M | 75 | 5 months | 10/26/2004 | 1 | adjuvant Rx Stage II prostate ca RT | Within a week severe palmar tingling, flexor contractures and bilat carpal tunnel and trigger fingers | Sx reached their peak about 6 weeks. Surgery at 7 month, open carpal tunnel trigger finger release but tenosynovitis swelling/contractures continue despite surgery and months of topical testosterone tried as antidote | M | 75 | 6 months 45 mg | 10/6/2020 | 4 | metastacised prostate cancer | Man boobs --- joint pain --- fatigue --- hot flashes | Started in May of 2022 after diagnosed with Stage 4 cancer. PSA @ 760. Given 6mos to live without treatment. Eligard brought PSA down to below 1.0 within 60 days (now at .2). Other than the listed side effects (which are somewhat tolerable), this drug has helped me thus far. May quit if quality of life decreases (in other words, if side effects get worse). It has given me time to get my affairs in order. God Bless All Who Are Going Through Similar Circumstances! | M | 72 | 10 months 1X O | 2/11/2023 | 3 | prostate cancer | hot flashes, no libido, fatigue, anemia | This med is effective (not a cure) for prostate cancer. There certainly are side-effects...and I am trying to limit time on this drug. Bigger doses create bigger side-effects. | M | 72 | 6 months 30mg-6 mo 2X AN | 8/26/2021 | 5 | Prostate Cancer | Hair loss from legs, arms, chest, Hot flashes, Middle weight gain, Reduced enegery level, Tired feeling a lot of the time,Loss of sex drive, Loss of sex intrest, Headaches, A lot of heavy phlegm. | I was diagnosed with Prostate cancer at age 67. I had a PSA every 6 months for 15 years. In Jan of 2002 the good PSA was 24 and the bad PSA was 3.5. The bad had been runnning from 3-4 for 3 years. In June of 2002 the good PSA was 18 and the bad PSA was 4.75. At that point the Urologist scheduled a Biopsy and the cancer was found in 4 of 5 samples. I was lucky sometines it is missed. My "Gleason" number was 8.5. I received the first 4 month Lupron shot in February 2002 to try to stop the cancer and shrink the Prostate. I underwent radical Prostate surgery in April 2002 and there were no cancer cells outside of the Prostate. They checked Lymph nodes and they were clear. Because of the high "Gleason" number I stayed on 4 month Lupron shots, receiving the last one in June 2006. My PSA has been lower than they can read since the surgery. It is now <.04. I took Megace "Megestrol" from June 2002 untill April 2006 for the Hot Flashes, it controlled them. Before | M | 71 | 3 years | 6/22/2006 | 4 | Prostate Cancer | Hot Flashes, Fatigue, Dependency(ie: when I am near the end of my 3 month cycle, my side effects are worse.) Neck pain, impotency(complete)When I do not get a full blown hot flash(it stops before completion) I feel terrible all over. | I have been taking Lupron as part of Triple Therapy Hormones, Radiation, Seed Implants. PSA is running less then.01%.Doing the job on the cancer but side effects are tough to deal with at times. | M | 70 | 2 years | 5/20/2004 | 3 | To shrink the prostate | Some mild hot flushing, mostly at night. Loss of libido and a restless feeling sometimes. Frequent urination at night. | I was given the 4 month shot to shrink the prostate in preparation for a radioactive seeding procedure. My cancer is early - T1. If the prostate doesn't shrink sufficiently, I'll have to undergo 8 weeks of daily external beam radiation which is more damaging to the tissues than the seeding procedure. | M | 70 | 5 weeks | 12/16/2005 | 1 | prostate cancer | brutal hot spells bad taste in mouth no energy swelled legs anxiety jitters depression strange smells memory loss | I feel absolutely awful,no information about side effects given,doc does not seem to care.I would appreciate comments from men about similar side effects or women who use lupron.This stuff is awful,I am also a hypochondriac I suffer health anxiety so each symptom worries me.I would not recommend using it but what else can we do? | M | 70 | 9 months 13.5 mg 3X M | 6/18/2017 | 5 | Prostate Cancer | My primary side effect is hot flashes. I may be experiencing some extra tiredness, but hard to tell if it is age or Lupron. My prostate and everything associated was removed, February 2006, so I knew my sex life would be over. Small amount of cancer, about one gram, still in my system. | I am on intermitent therapy. I take a monthly shot, 7.5 mg., until my PSA is less than .1 for two months. Therapy then stops until my PSA goes up for two bi-monthly tests. I continue to be active physically riding an excercise bike and lifting weights almost every day. I also play tennis once or twice a week. I have lost about 10 lbs. in the last year as I have also watched my diet, primarilly less red meat. I return to M.D. Anderson annually for a check up. Just had first annual check up and considered in excellant shape. | M | 69 | 12 months | 7/12/2007 |
LUPRON DEPOT (LEUPROLIDE ACETATE): Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment. FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)