Drug Ratings for LUPRON DEPOTAverage Rating: 3.1 (723 Ratings)
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Results are sorted by Gender with males listed first Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
| RATING | REASON | SIDE EFFECTS FOR LUPRON DEPOT | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 5 | prostate cancer | I seem to be the poster patient for this medication. Hot flashes,(mild)weight gain (10-15 lbs.)pretty close to zero sex drive,slight breast enlargement( weight lifters chest)loss of body hair, (especially on legs where clothing rubs)mild loss of energy ( from a type A to a type B or C) which feels pretty good to be able to relax and not feel guilty about it. | After radical surgery. Thirty-nine radiation treatments and up and down PSA readings over the past seven + years it feels good to have a PSA of <0.01.How long it lasts we will see,but it feels pretty good for now. I have had two ,three mo. shots. I am off now for six months or until my PSA starts rising.The side effects are mild compared to the alternative. Now that I have been off it for a month some things are getting back to some semblance of normal. | M | 62 | 6 months | 2/5/2006 | 5 | Prostate Cancer | Hair loss from legs, arms, chest, Hot flashes, Middle weight gain, Reduced enegery level, Tired feeling a lot of the time,Loss of sex drive, Loss of sex intrest, Headaches, A lot of heavy phlegm. | I was diagnosed with Prostate cancer at age 67. I had a PSA every 6 months for 15 years. In Jan of 2002 the good PSA was 24 and the bad PSA was 3.5. The bad had been runnning from 3-4 for 3 years. In June of 2002 the good PSA was 18 and the bad PSA was 4.75. At that point the Urologist scheduled a Biopsy and the cancer was found in 4 of 5 samples. I was lucky sometines it is missed. My "Gleason" number was 8.5. I received the first 4 month Lupron shot in February 2002 to try to stop the cancer and shrink the Prostate. I underwent radical Prostate surgery in April 2002 and there were no cancer cells outside of the Prostate. They checked Lymph nodes and they were clear. Because of the high "Gleason" number I stayed on 4 month Lupron shots, receiving the last one in June 2006. My PSA has been lower than they can read since the surgery. It is now <.04. I took Megace "Megestrol" from June 2002 untill April 2006 for the Hot Flashes, it controlled them. Before | M | 71 | 3 years | 6/22/2006 | 5 | prostate cancer | Hot flashes, enlarged breasts, decrease in energy level | Have had PCa for 8 years; 2 reoccurences after radiation and thermal therapy PSA dropped to 0.12 Seems to be under control with lupron depot.I hope it continues. I have a friend who has been on it for 5 years. PSA is still undetectable. Original PSA was 92 with originally a T2B and a 7 Gleason. Reoccurence after radiation, went directly to Lupron.Age 66. I am optimistic this will buy me more time but realize eventually this becomes refractive as the body gets used to the drug | M | 66 | 1 years | 12/18/2005 | 5 | Prostate Cancer | Weight gain (30 lbs, 14% body fat to 24% body fat); inability to lose weight; general decrease in vitality; total inability to get erection; zero motivation for sex; some loss of body hair; tire easily-have to nap every day; discontinued strenous multi-day outdoor activity due to uncertainty about energy level. Up 3-6 times a night to urinate; occasional depression. Cool, huh? | I have tried to maintain an aggressive exercise program (weight lifting, biking, some running, spinning class) but my aerobic health and strength levels have continually declined while on Lupron. I feel much older. I feel as if I am continually declining, not making progress to better health. PSA is down to less than .01 after IMRT and Taxotere Chemotherapy (Gleason 9 cancer)so it is working. I have had to begin to turn down invitations to do physically oriented activities due to my level of health. | M | 60 | 21 months | 4/10/2006 | 5 | PROSTATE CANCER | HOT FLASHES | PSA IS .01 AND LUPRON INJECTIONS HAVE BEEN VERY SUCCESSFUL! | M | 69 | 14 years | 8/21/2007 | 5 | prostate cancer | Loss of libido. Diminished size of testicles. No hot flashes. No weight gain. No muscle weakness. Continued all excercise regimins of resistance and biking and started swimming lessons at 4 months into Lupron. I even increased the weights on resistance machines. | After reading the comments of others, I was dreading starting Lupron/Depot but other than the two listed side effects, my life has continued exactly as before including all exercise programs which average about an hour a day. Also had 38 radiation treatments on Varian Associates Trilogy machine during this time. | M | 80 | 5 days | 5/2/2007 | 5 | prostate cancer | my last rating recorded 5 days and it has been 5 months since I started Lupron | M | 80 | 5 months | 5/2/2007 | 5 | Prostate Cancer | My primary side effect is hot flashes. I may be experiencing some extra tiredness, but hard to tell if it is age or Lupron. My prostate and everything associated was removed, February 2006, so I knew my sex life would be over. Small amount of cancer, about one gram, still in my system. | I am on intermitent therapy. I take a monthly shot, 7.5 mg., until my PSA is less than .1 for two months. Therapy then stops until my PSA goes up for two bi-monthly tests. I continue to be active physically riding an excercise bike and lifting weights almost every day. I also play tennis once or twice a week. I have lost about 10 lbs. in the last year as I have also watched my diet, primarilly less red meat. I return to M.D. Anderson annually for a check up. Just had first annual check up and considered in excellant shape. | M | 69 | 12 months | 7/12/2007 | 5 | prostate cancer | Tiredness and bowel problems but this may be due to old age. | PSA reading shot up to high twenties and an operation was considered but I chose the Lupron injection treatment every 3 months. 'Something else will probably kill you first' was one bit of advice. My latest PSA reading was under 2 so I am pleased with the results so far. | M | 81 | 2 years | 7/24/2009 | 5 | Prostrate Cancer | Constant urge to urinate; Hot Flashes. Hard to sleep and lost of strenght for sex | M | 60 | 6 months | 11/16/2009 | 4 | ProstateCancer | Hot Flashes. Total loss of libido. Unable to get eractions | Been on Lupron for 5 months. Second shot hurt so bad could hardly walk for 3 days. PSA went from 38 down to 2.4 so it is working. Going to go intermittent to give body a chance to recover. Trying to keep from surgery/radiation if possible. | M | 795 | 5 months | 12/23/2009 | 4 | Prostate Cancer | It's been 6 weeks since I was injected with 22.5 mg Lupron to reduce the size of my prostate. My prostate needs to become smaller so that I can have seed implants. So far I have not had any adverse effects. Insomnia was a problem I had prior to the Lupron so I can't attribute the drug to that problem. Wheter the drug is working or not will be determined in about 7 weeks when the volume check will be done. | Nothing more to say except, I was expecting all the side effects, but after 5 weeks, can't say that I have experienced any.I will continue to keep my fingers crossed. One other thing. I saw how much my health insurance company was billed for the shot and understand now why the health business in this country is going to collapse soon unless something is done. $3433.00 | M | 35 days | 5/27/2009 | 4 | prostate cancer, bone metastasis | Osteoporosis, hot flashes, skin reaction (Eczyma), sex change: (impotence, grow belly and breasts, atrophy elsewhere) | Sommer 2007: Severe back pain. Prostate cancer was discovered, PSA over 500. It was in by bones, the fouth vertebrae. 11 radiations got rid of pain, but was too strong, closed my troat, could not speak, could not eat, lost 20 lbs in a week, almost died (got bill anyway), Recovered. (doctors prescribed mouth wash, did not help, my wife broke up Aloe Vera jells and fed them down my thoat, it gradually opened my throat). Since then getting LUPRON DEPOT injections first monthly, then every 3-4 months. PSA December 2008=0.85. Great. But side effects are bothersome. Will suggest skipping one injection, to see what PSA does. Only if it goes up again will I ask for another injection. Also will do another bone density test, which will show the osteoporosis or not. maybe I beat the cancer yet. | M | 83 | 15 months | 12/9/2008 | 4 | Endometriosis | Occasional night sweats, weight gain | This is my 6th month on this medication. I get a shot every 3 months. I had surgery to remove my right ovary and fallopian tube due to cysts and endometrioma. My OB-GYN put me on this drug so I will be on temporary menopause and hopefully help with keeping the endo at bay. Don't get scared to try this med, each patient will react differently. Fortunately, I did not experience all the side effects that affected others. The worst side effect for me is the weight gain. But hopefully, I will lose it when I stop with the treatment. | M | 46 | 6 months | 10/1/2008 | 4 | prostate cancer | impotence, breast tender and swelling, back and leg pains | started lupron 3/06 3 weeks before 42 imrt treatments for gleason 7, psa 4.3, t2c, scans negative outside prostate area. i really hope this increases odds of no reacurance, however i don't know if i can take my next shot, the side effects are bad and i can't find any conclusive study/research that proves this extends survival, beyond what occurs with high dose radiation even dr. says it is not showing great increase in ongoing RTOG trials just now ending, but does show small improvement, final data on full 2 years of lupron coming soon. THE GOOD NEWS IS MY PSA HAS BEEN <.1, AND I HAVE TREMENDOUS FAMILY SUPPORT. may GOD bless you all. | M | 55 | 17 months | 7/15/2007 | 4 | prostate cancer stage 4 | The most disturbing side effect has been that Lupron has caused inflammation(feels like heart burn) in my stomach and small bowels. As a result I want to soothe the burning by eating all the time. My waist size has gone up two inches and my weight by twenty pounds over the period of a year. The standard medication of heart burn (tums, zantac, etc.) does help to ease the burning in my stomach but not in the small bowels. | Lupron has lowered my PSA to 0.0 and effectively supressed any libido which at my age (76) is something I can live with. I would be an enthusiastic user but for the heartburn and weight gain. | M | 76 | 12 months | 7/18/2007 | 4 | Prostate Cancer | Slight anemia, probable aggravation of conditions either already existing or oncoming: high blood sugar, low energy, restlessness, lack of libido, increasing irritability, decreasing body hair, skin reverting to baby-like smoothness. | Works for me: TRUS and biopsy showed cancerous or precancerous cells throughout 2/3 of prostate that was 11 times normal size; PSA 6.8, Gleason 7. After two 3-month Lurpon injections and one month on Casodex, prostate was half as large but still twice operable size; PSA <.4. Main gripe is damn surgeon didn't speak one word to possible side effects; just a faint smile when I bring yet another symptom to his attention. Started out with a few strikes against me anyway: bi-polar with panic-anxiety disorder and hugely overweight, heavy drinker for years. Meds, age and bad habits have brought on adult-onset diabetes which I am now sure is aggravated by Lupron. Before all this, however, am sure I underwent "male menopause" at precisely age 40: loss of energy and interest in formerly enjoyable pursuits including sex, raging night sweats for several years with highly disrupted sleep. Got past all that, so Lupron had noplace to go except straight to now-shrunken gonads and prost | M | 61 | 17 months | 2/2/2008 | 4 | Large Uterine fibroid- pidaua | I have been on Lupron now for 2 weeks. I posted earlier (see under pidaua) and the only other side effect I can add was another period that began 7 days after the first injection. It lasted only 5 days but was heavier than normal. I felt wiped out, but that may be due to lack of sleep because of the stress of my husband being in Iraq. | I have to encourage people to take their vitamin supplements and get exercise even if you don't feel up to it. Yoga and lots of walks have helped me tremendously. My lower abdomen does not feel full and my body is getting back to the shape it was in before the large protrusion caused by the fibroid. I believe that those with fibroids have an easier time that those with endometriosis. Then again, there will always be some that complain about any medicine under the planet because they are against pharmaceutical companies. Be informed. | M | 37 | 2 weeks | 5/8/2007 | 4 | Prostate cancer | Fatigue, irratibility, insomnia, swelling in hands and feet, weight gain of 20 pounds, some depression, lack of sex drive, tingling and itching in extremities, occasional night sweats. | I am on the second of a scheduled 3 injections. Had IMRT treatment for PC. PSA went from 9.9 to .01. Lupron side effects are hard to take, but if it does the job, I can take it. | M | 62 | 6 months | 6/11/2005 | 4 | advanced prostate cancer bone mets | Fatigue, hot flashes, arthritis, loss of balance, depression, enlarged breasts and weight gain.Still work full time but with a flexible schedule. PSA 0.2 Cancer is stable with no additional metastasis. | M | 57 | 2.5 years | 7/18/2005 | 4 | Prostate Cancer | Severe shortness of breath, night and day sweats and total loss of libido. | My version is of leuprolide acetate is called Eligard. Does a good job of keeping my PSA to less than 0.1 but I also have the Alpha 1 deficiency which amounts to inherited emphysema. I was functioning normally despite the Alpha 1 before I received the first four month injection. Severe shortness of breath began immediately after the first injection. The condition of my lungs hasn't changed for two years and my pulmonary MD sees no reason for the change and attributes it to leuprolide acetate (Eligard). Recently had the fourth injection and shortness of breath worse than ever. Is there an alternative drug? The side effect is turning me into a couch potato. I am really considering stopping the treatments. Walking accross the room results in shortness of breath. I thought this info would be helpful to anyone unfortunate enough to have prostate and lung illness. | M | 67 | 1 years | 10/6/2006 | 4 | High PSA reading | Hot flashes | PSA reading dropped from 35.8 to 0.2 | M | 75 | 5 months | 10/26/2004 | 4 | prostate cancer | Hot flashes,weight gain (22#), muscle weakness, swelling in extremities. I work out 5-6 times a week, but have backed off on my running program. The extra weight makes it hard on the feet and legs. Hopefully the treatment will work in conjunction with the cryosurgery in a few months. | M | 55 | 5 days | 6/28/2004 | 4 | prostate cancer | My submission earlier showed 5 days. It should be 5 months | M | 55 | 5 months | 6/28/2004 | 4 | PROSTATE CANCER | HOT FLASHES,BONE PAIN. WEAKNESS. LOW SEX DRIVE | IF WILL HELP KEPT BE ALIVE I CONTINUE TO TAKE IT. | M | 63 | 3 years | 5/16/2004 | 4 | Prostate Cancer | Hot Flashes, Fatigue, Dependency(ie: when I am near the end of my 3 month cycle, my side effects are worse.) Neck pain, impotency(complete)When I do not get a full blown hot flash(it stops before completion) I feel terrible all over. | I have been taking Lupron as part of Triple Therapy Hormones, Radiation, Seed Implants. PSA is running less then.01%.Doing the job on the cancer but side effects are tough to deal with at times. | M | 70 | 2 years | 5/20/2004 | 4 | Prostate cancer | Hot flashes, fatigue, loss of strength, loosing body hair, mild depression, irritable | Injection every 4 months. As long as it can prolong my life I will continue taking. | M | 56 | 18 months | 3/26/2004 | 4 | prostate cancer | Hot Flashes, Fatigue, Dependency(ie: when I am near the end of my 4 month cycle, my side effects are worse.) Neck & back pain, impotency(complete) Hot flashes. I feel terrible all over. | Injection every 4 months. My doctor tells me it is up to me as to when I may stop the injections. Most take for only 3-5 years and if the cancer comes back...what then? Maybe some other treatments may work. I would like to know more about tistical removal. Seems to make more sense to me. | M | 49 | 3 years | 2/7/2005 | 4 | Prostate cancer | Hot flash, weakness in my arms and legs and weight gain. Regmiment of treatment has been, radical surgery, 1 l2/2 years later 36 radiation treatments, year later, Casodex and Proscar, Now Lupron depot. First treatment Sept 04, January 05 PSA was 0.0 next test first of may. | So far it is doing the job, reducing PSA, | M | 64 | 6 months | 4/18/2005 | 4 | Prostate cancer | Injection site pain on occassion. Weakness in hips and lower back so use a weight lifters belt when picking things up. Digestive system problems with gas. Insomnia so take a sleeping pill every night. Wake up from 3 to 6 times per night to urinate. Hot flashes with sweats that I have gotten used to. Absolutely no sex drive or interest-to castrate level for sure. | I had a Gleason 6 cancer and underwent 45 IMRT radiation treaments. My PSA was 52.0 and is now down to .7 which shows that this combination was the best for me. Even though I have no sex drive my relationship with my wife has reached a higher level and we spend a lot of time massaging each others back and feet. But since I get up a lot at night we have to sleep in separate rooms. I will be on Lupron for another year and the side effects last from 6 to 9 months after treatment. I won't know if this was the cure until this time passes and we check my PSA. | M | 59 | 10 months | 6/29/2006 | 4 | pprostrate cancer/bladder cancer | I have only been on Lupron for one month. Had my 2nd shot today, 2/26/07. Had tumors removed from bladder on 2/6/07 and am under treatment for that also. I have noticed a lack on energy, some night sweats, and frequent urinatin at night. No weight gain yet (could use some anyhow) and will not get a new PSA test until third shot next month. Doctor is very efficient and doing good job on treatment and followups. Will update later. | M | 67 | 30 days | 2/26/2007 | 4 | Prostate cancer | impotence, loss of sex drive, hot flashes, weight gain (30lbs), irritability, dry skin, depression. | Well, I am alive. PSA is under relative control, fluctuates from 14 - 18. Sex drive gone, wife probably happy, me I don't know the difference anymore. Weight gain is the worst, getting harder to keep pants up. Problems with knees due to excess weight. Haven't figured out a way to keep off the weight. | M | 65 | 5 years | 8/9/2005 | 4 | Prostate Cancer | Hot flashes, I tire easily with the slightest exertion, weakness, irritability, mood swings, shortness of breath, all of these side effects are continuing still this time though I have been off the lupron for over 3 months | second round, first 1 year this time 8 months, the treatment worked both times though the results the second time were not as good as the first. | M | 59 | 8 months | 1/5/2006 | 4 | fibroids | Vaginal dryness and hot flashes, otherwise I feel fine. My energy level in increasing. I feel extra hungry however. No weight gain yet. | M | 45 | 2 months 1X M | 5/14/2010 | 4 | endo | nausea, migrain, HOT flashes. | There are a lot of negative comments about the shot. I must say the side effects are not fun at all, but I would trade the side effects anyday for the endo pain. It has been sooooo amazing not having the pain. If you have endo and suffer from the same pain then the side effects of Lupron will seem like a very very small price to pay. It has been 4 months from my shot. My only worry is that the pain will come back. Also I have not had a period yet. I am not sure how long that will take. I will post an update when I do start and/or if the pain comes back. I would like to know how long it takes to start your period again because my husband and I would like to start trying for a baby! So if anyone as any info on the after treatment and TTC please let me know. | M | 28 | 3 months 3month 1X M | 12/4/2010 | 3 | Prostate cancer metastasized bone | Only been a week. Tired and painful in butt where shot was given. Pain in my hip and lower back | I was diagnosed last week with prostate cancer that has spread to lymph nodes and bone.My first 4 month shot was last Monday. I have blockage in bladder and have tube to external bag which will remove next week. PSA 210 AND GLEASON 9. I am very hopeful and know it is very early. I am only 44 and have wife and two young kids. Thanks everybody for input - I have a million questions. | M | 44 | 7 days 7.5 1X M | 10/13/2010 | 3 | hormone supression | hot flashes first started 3 days after injection. dizziness. had a menses with cramping -flow was shorter and lighter. | ftm guinea pig [genetically female] 7.5mg Q 4 wks prescribed this response is after 1 injection | M | 14 | | 3/3/2006 | 3 | To shrink the prostate | Some mild hot flushing, mostly at night. Loss of libido and a restless feeling sometimes. Frequent urination at night. | I was given the 4 month shot to shrink the prostate in preparation for a radioactive seeding procedure. My cancer is early - T1. If the prostate doesn't shrink sufficiently, I'll have to undergo 8 weeks of daily external beam radiation which is more damaging to the tissues than the seeding procedure. | M | 70 | 5 weeks | 12/16/2005 | 3 | PROSTAE CANCER | I FEEL LIKE I'VE BEEN UP ALL NIGHT, ALL OF THE TIME. I'M MORE IRRATABLE THAN USUAL, AND REALLY FEEL LIKE AN OLD MAN | M | 55 | 3 weeks | 4/6/2005 | 3 | Prostate cancer | Mild mostly, occasional hot flashes, less body hair, less libido. Weight gain around middle, anxiety. | Will not know for 6 more months if it has helped. | M | 56 | 6 months | 12/26/2002 | 3 | PROSTATE CANCER | AT BEGINNIG HOT FLASHES THAT ALMOST QUIT AFTER 6 MOS, OR SO. TIREDNESS TOO OFTEN, DAYS I HAVE THE JITTERS FEELING INTERNAL NERVOUSNESS,COUGHING SPELLS,DRY MOUTH, BAD TASTE IN MOUTH,WATERY EYES & AT TIMES DRY EYES,OCCATIONAL ACHES & PAINS TOO MANY DAYS FEELING OF GO TO HELL ATTITUDE.MY OVER ALL GENERAL HEALTH HAS DETERIORATED THE PAST TWO YEARS.I'VE KEPT RECORDS THE PAST FOUR YEARS OR SO. | SINCE IT DOESN'T CURE THE PROBLEM I'M CURIOUS ABOUT OTHER TREATMENT THAT MAY CURE IT. RATING SATISFACTION AT THIS TIME IS DIFFICULT BECAUSE OF MORE INJECTIONS IN THE FUTURE.*** | M | 82 | 9 days | 6/24/2005 | 3 | prostate cancer | I had one hot flash that lasted for 2 days. Temp went from 101 to 103 and never lower. Loss of energy, easily tired. Lost 20 Lbs. 4 month injection. Wound up in the hospital with internal bleeding. Total confusion and felt like I was watching myself in a movie. At this stage, (40 days) nasty symptoms have for the most part, passed. (my fingers are crossed) The radiologist wants to keep me on this stuff for 2 years!!!!!!!!! Might look into the nearest funny farm to see if there are ex clients there. Is this the way it is supposed to be? | PSA 68...Gleason 6, Stage T1c Have not got back any results on the latest PSA test. | M | 63 | 40 days | 8/20/2007 | 3 | severe endo | hot flashes, acne, headaches, nausea, tired and weak, backache, depression, overwhelmed, constipation, painful urination, mood swings, memory loss,return of acid reflux, head feeling foggy, difficulty concentrating, weight gain, I never had any diet changes, didn't eat no more or no less, female organs ached unlike I ever experienced before By this time who cares about having a sex drive--This is my 2nd posting | My side effects were just as bad as when I started out with the severe endo and a cyst that took over my left ovary and tube. I started out going to the dr. in Feb. 04 hoping to get help and treatment. By March 04 I had my first surgery in which I had the cyst, ovary, tube and what endo the Dr. gould get without damaging my organs, which were stuck together. I started my 1st treatment of lupron that March. As I said before my 1st 3-4 months I felt better than I had in years, side effects mostly hot flashes and some nausea. Within 5 months I developed all side effects listed. I had a 2nd surgery in Oct. 04 in which the dr. was able to remove all endo which I can say the shot done its job and shrunk all the endo that had my organs attached. Praise God! My last treatment on lupron was April 05. It took 4months for me to have a period. 6 months to loose the 1st lb. gained from shot which slowly but surely is coming off with regular exercise and trying to eat right. Walking is a wond | M | 30 | 1 years | 1/14/2007 | 3 | Prostate Cancer | weight gain,total insomnia,fatigue,upset stomach,hot flashes, chills,mood swings,irritability,unsteady on feet,short term memory loss,jumpy, & the "big one" muscle aches all over body weakness in legs.Hard to even walk some days. Of course sex-now non existent also. High chlosterol & blood pressure also. I had none of these problems , except insomnia before Lupron.The muscle aches & leg weakness has only occured after 8 month shot. | I hate this stuff...gleason 8, T1C,5.2 PSA. If not for wife & kids would stop immediately. Quality of life is "non existent". 1 year to go on 4 month shots.I still may quit Lupron after next shot or before it. PSA is .03 after 43 days IMRT Radiation & 8 mos Lupron. | M | 66 | 11 months | 6/28/2007 | 3 | Prostate cancer | Hot Flashes, tired, moody, lower back aches | Have had 2 X 3 month shots and have stabilized PSA after a radical 8+ years ago and 44 radiation treatments 5 years ago. PSA increased 30-50% every 3-6 months--so I really hope this works | M | 64 | 5 months | 3/30/2007 | 3 | Prostate Cancer | Weight gain. Incredible shortness of breath. Unsteadyness on my feet. Even with regular exercise and walking I still feel terrible. I tire easily with just the slightest exhertion. I'm also impotent and testicles have shrunken. Can tell when it's time for the next 4 month shot because I always start to feel better. | Doctor wants to keep me on Lupron one more year. I still have problems with urination and getting up 4-5 times a night. | M | 68 | 1 years | 5/6/2005 | 3 | Prostate Cancer | Hot Flashes,some leg pain,some fatigue, some mental fuzziness,increased night urination. Haven't had more than 3 hours of sleep consecutively since injection 3/6 | PSA level 29, Gleason 7-10, CAT scan and Bone scan ruled out metastasis. DaVinci Prostatectomy scheduled 6/18. First symptom was leg pain that lasted a few weeks, but went away. Hot flashes are biggest negative. Dr. tried Clonidine, but didn't seem to help. I was very active before the injection (running 10-15 miles/week plus lifting weights). Continue to run and lift weights 4 days a week(with a some loss of endurance and strength, but not bad) Due to increased sweating, I have to make sure my fluid levels are kept up. Changed diet completely, no red meat, a lot of soy, fish,grains,juice. Lost 12 lbs. and feel pretty good. Some days I seem like I can go pretty good, but then hit a wall and am wiped out, but I just go with it and wait until I feel better. Don't know what rating to give the drug, since my PSA won't be tested until after the surgery. I have faith in the course of action my Dr. is taking and hopefully will report back the results. | M | 61 | 80 days | 5/18/2007 | 3 | Prostate Cancer | Many side effects, mostly manageable but some of them serious. | Urology Dr gave me a 4 month shot prior to seed implants to get me prepared. PSA 6.5 and Gleason 7 lymph biopsy shows no spread. He said I would be on it for 2 years. Side effects started right away and just continued to get worse. It got so bad my family Dr. put me off work because I could not sleep whatever I took and my mental state was so bad. Oncology Dr. said he was not giving me any more Lupron. The worst effects are not sleeping, exhausted all the time, mental confusion, memory loss, bad balance. Had the implants 1 week ago. We will see what happens. | M | 61 | 3 months | 4/6/2009 | 2 | Prostate cancer | Hot Flashes, Joint pain, Neck pain, Tender & larger 'breasts' Perpetual tiredness + haven't put together >3 hrs sleep continuously in 1.5 yrs without chemical help. Libido=0, if the penis shrinks any further, I'll have to remove Mr in front of name. | The original plan was 12 injections, coming up on 5 & I'd get off tomorrow except "does it make these 5 a waste of time etc?" I'll be asking next visit b/c if there is little difference. I get the shot in the butt, the 1st injection site on one side still hurts after >1 year. | M | 53 | 1.5 years | 2/17/2008 | 2 | prostate cancer | anger, sweats, mood swings, crying, body odor, weakness, vision changes, dry mouth, chills, can't remember things, depression, sleeplessness, irritability, loss of appetite. | Husband Could not do the three years recommended by dr. only one year...studies showed no difference in prognosis after three years than 1 year anyway- States he would rather be dead, than to take this medication ever again. | M | 63 | 1 years 1X M | 10/7/2010 | 2 | Endometriosis | Hot flashes( at least 1 per hr all day & night), night sweats, trouble sleeping, mood swings, irritability, depression, extreme fatigue, slight hair loss, slight headaches, decreased sex drive, vaginal dryness | Took this shot for 6 months in 2009 following a laporoscopy and removal of my right ovary, in hopes of suppressing my endometriosis. Endometriosis still came back even after the 6 months of injection and birth control. Just had another laporoscopy in Aug 2010 on my left ovary(which is thankfully saved!). Have been put back on this shot for another 6 months. Side effects seem to get worse with each injection, especially the hot flashes. I also feel extremely fatigue all the time and very moody and feel depressed sometimes. Hopefully it will help a second time around. Kind of glad I found this site because at least I know I'm not the only one experiencing these symptoms and reading these other experiences help me to be more cautious with this medication. | M | 23 | 2 months 1X M | 10/5/2010 | 2 | Prostate Cancer Gleason 7 3+4 | Extreme mood swings, crying 4x's a few days a go, ultra sensitivity to everything, wanting to run away from the people I love, loss of all sexual interest. I am also taking Avodart and Casodex part of triple blockade ADT but my doc is stopping Lupron feeling it is causing me to feel insane. | M | 63 | 3 months 7.5mg 1X M | 1/28/2011 | 1 | prostat cancer | hard to uranate or take a dump could not digest food guts were so hard thay hurt hot flashes that just made me teem | i hate the stuf i will never take thyat shit again | M | 55 | 120 days | 11/1/2005 | 1 | prostate cancer | fatiqued and tire all the time.no sex drive or interest in sex. hot flashes and night sweats. Mood swings and drepression. Swollen hands. | M | 62 | | 7/7/2006 | 1 | Prostate Cancer | Enlarged Breasts, Night sweats, weakness of the legs, swelling of the legs,loss of balance, weight gain 30 pounds, 5 emergency room visits with heart attack / stroke symtoms, irratable, mood swings | Only one, three month injection, a year and a half later I still have problems with my legs, weight, sleep habits, etc. | M | 52 | 1 times | 7/24/2005 | 1 | M | 26 | 1 months | 6/18/2003 | 1 | prostate cancer | Temp: hot sweat Permanent: Low back ache, weak legs, unsteady gait, tire easy. | I was on lupron for 1 1/2 years. The adverse reaction was so bad I sought a second opinion. The second urologist took me off all medication. My prostate has never bothered me and I havebeen off lupron for 1 1/2 years. | M | 85 | 1 years | 11/14/2004 | 1 | prostate cancer | Enlarged breasts. Weak lower extremities, low back ache, loss of torso hair, unsteady gait, shrunken penis, loss of energy. | Bad news for me. | M | 85 | 1.5 years | 1/9/2005 | 1 | prostate cancer 13.7 PSA gleason 7 | I refused surgery, I won't have chemo. At the time May 2, 2009 I thought brachytherapy was my only option. Then I found proton therapy. I had 2 weeks of tests done. ...>MRI Pelvis w/wo contrast NM Body scan-whole body ...>NM inflammatory prostascint test ...>Prostascint scan ...>CT ABD pelvis scan with contrast ...>will get a transrectal ultrasound in 2 weeks The cancer has not spread outside the prostate. While in testing, away from home, the radiology oncologist recommended LuPron Depot 22mg. Not aware of the side effects I consented. After returning home I have found this was one of the worst mistakes I have ever made. This drug has so many side effects, major side effects not just the head aches and weight gain. Then after doing some major research I found a drug that would help considerably if I had "NOT" taken the Lupron. Now it is to late for the alternative, "Low dose Naltrexone", I am in search of another method over radiation | Lupron is a pharmaceutical get rich drug. Please do your research and the side effects and how it is affecting peoples lives. Don't consent until you know everything you can about this drug. | M | 53 | 25 days | 5/26/2009 | 1 | endo and in a lot of pain | hot flashes, hair loss, acne, water retention, weight gain,lower part of abdominal swelled up, depressed, angry, forgetfull, | Ok, so in 1999 I was diagnosed with Endo. Up until then, I though I just had really bad periods. I had 2 laporascopy surgery, and with each surgery the endo was worse everytime, and now I have a lot of scar tissue and the endo is back. the pain never went away and it's so bad to the point where I cry. So, my doctor told me that if I wanna get rid of the pain is to take out my uterus and my left ovary, but that is not an option, we want more kids. Then she decided to put me on the lupron depot shot, every 3 months for 9 months. She told me about some of the side effects, (some), but said they would go away. So, first 3 months, it wasnt as bad, except for the hot flashes and the night sweats which they never went away. The good part was, no period and the pain is gone. Well, my last shot was in March 2009 and ended in June 2009 and as of right now, still no period. The worse part is that all the side effects are back, some are really bad and they are not going away. I started to loose my hair,not able to loose any weight and my belly swelled up (looks like I am pregnant), joint pain, very angry, very depressed, i cry a lot, night sweats, hot flashes, forgetfull sometimes. On top of that, i get so angry, to the point where I cannot control myself and i start crying. I havent had a period in more than a year now, and hope to get it soon and have more kids. Too bad my doctor didnt tell me all this and had to find out on my own. | M | 32 | 9 months | 10/11/2009 |