Drug Ratings for ZOLADEXAverage Rating: 3.1 (167 Ratings)
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Results are sorted by Satisfaction from lowest to highest Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 |
| RATING | REASON | SIDE EFFECTS FOR ZOLADEX | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 1 | IVF | I have had severe headache on both sides of my head.I regret taking this injection! | F | 40 | 1 months 3.6mg | 4/29/2013 | 1 | Menorrhagia/pre-uterine ablation | Emotional liability, severe bleeding, memory issues, fatigue, hot flushes | This drug did not work, in fact, it had the opposite of the intended effect. My blood loss has gotten so bad that I've gotten badly anemic and my period just no longer stops. I have to be in progesterone 3 times a day just to slow it down. | F | 43 | 1 times 10 1X O | 3/17/2013 | 1 | Severe Endometriosis | Suicidal thoughts and depression. Constant hot flashes and huge weight loss. | F | 23 | 6 months N/a | 11/26/2012 | 1 | Breast cancer when young.. | Hot flushes pain in stomach from implant..constant sick feeling itching..pins n needles..being sick..and it didnt stop periods like it was meant.. | F | 43 | 2 years 25 | 10/19/2012 | 1 | Prostate cancer | Jaw twitch, headache, waves of nausea whole day, irregular heartbeat, difficulty breathing, can't sleep, general weakness, loss of memory, muddled thinking anxious, super sensitive skin, hurts to touch things, quality-of-life here is near zero, taking this will make you wish that you were better off dead, advice, don't take this stuff | Take this drug off the market | M | 71 | 3 days Injection 1X AN | 7/16/2012 | 1 | Gyne proba | Hot flushes, extreme confusion, tearfully, depressed, mood swings, abdo pains, foggy head and could barely string a sentence together. | F | 35 | 2 months 3.6 mg | 2/29/2012 | 1 | endo | extreme hot flushes, fatigue, exhaustion, moody, close to tears often,weight loss, dry mouth, constipation | This drug did not help one bit other then the no periods. The pain during intercorse didn't stop at all and the hot flushes were chronic and interupted my day to day activities. Even though I didn't have my period it felt like I did for the whole six months just no bleeding. my last injection was 3 months ago and my period has returned and I have had it for 20 days even though I am on the pill. My gyne is not the greatest in the world and believes that Zoladex is the cure and that it should have worked on me and she is refusing to do surgery. | F | 23 | 6 months 1X M | 9/20/2010 | 1 | Endrometriosis | Hot flushes, night sweats, moody, loss in libido, headaches, acne, sore breasts, | Taken zoladex for 2 months now and unfortunately I am still in pain but I also have the side effects of the zoladex. I had a partial hysterectomy last year and had the zoladex for 5 months which helped a lot I was like a new woman but unfortunately the endrometriosis has come back and this lot of injections are not helping. I am very lucky as I have got 3 children. | F | 30 | 2 months 1X M | 9/10/2010 | 1 | endometriosis | sore boobs, sharp pains in boobs, stomach pains, origional pains not subsided back and leg pains no better, severe anxiety(im actually worried by how bad it has become so quickly), flushes, sweats, insomnia, dizzyness, fuzzyness, forgetfulness, lack of concentration, headaches ( also noise seems alot louder than usual and irritates), shakes | only my first injection the injection its self didnt bother me but the side affects i dont think i can handle, the pain im suffering from seems to of gotten worse not better, i have had no releif as yet and the side effects i feel may not be worth it, i am suffering from severe anxiety, crying all the time, panicing, i feel lost or something im not sure, if im left on ly own im scared and cant stop myself from cring, this has only come on since the injection (implant) i am going to docs tomorow to see what my options are, i cant have another 5 months of not being left alone and panic, i keep running through everything all the time, its like constant butterflies in my tummy! aswell as all the other side effects im seriously doubting zoladex worth for myself! i have had not much help from my gynae specialist im hoping my doc can do something | F | 33 | 3 weeks implant 1X M | 9/6/2010 | 1 | endo,cystic ovaries,adenymosis | urinary problems, night sweats, depression/anxiety, insomnia, moodiness, joint pains, loss of libido, brain fog, fatique. | After more than 25 years of chronic pelvic pain and multiple surgeries for polycystic ovaries, endo and adhesions, I agreed to take Zoladex in preparation for surgery for Thermachoice and laparoscopy. Surgery was successful as there was no evidence of endo either in the pelvic cavity or uterine wall. The side effects of the drug impacted severely on my quality of life and if I had been in a better space and not consumed with desperately trying to find relief from chronic pelvic pain, I would have thought long and hard before agreeing to take this drug. My husband of 28 years said that if I had contd. taking this drug our marriage would have been in serious trouble. Think carefully before resorting to this drug! | F | 47 | 5 months 3.6mg 1X M | 6/4/2010 | 1 | prostate Cancer | I take the injection once every 3 months. I have been feeling muscula joint pain, weekness, loss of appetite, swollen feet, bone pain, energy loss, hard to lift myself, can't walk, and get tired fast. | M | 86 | 12 months 10.8 mg 4X O | 5/16/2010 | 1 | stage one breast cancer | A walking zombie, , just a slow one!!! I felt spaced out/flat affect/severe hip pains/nausea daily/ slept 12-14 hrs day and still fatigued- yes, a zombie aged 100!! sums it up well. | Oncologist sugg. not doing this any more. Had good chemo regime and some on/off attempts wih Tamox. ( also, had severe bone pain, so , ceased that) ( P.S every one's response is very very different and the advice above suited my diagnosis only) Most likely i would have same symtoms with oopherectomy, so, advised against that also. QUALITY of life is what counts for me and on Zoladex I had zero. I now look forward to getting on with life without pain/fatigue, and thats better than winning a lottery::) | F | 47 | 1 months 3.6 mg inj 1X M | 5/6/2010 | 1 | prostate cancer | muscular and joint paine | M | 87 | 1 years 10.8 1X AN | 4/30/2010 | 1 | Stage 4 - Breast Cancer Mets | Hot flashes first few months; headaches; dizziness up to 1 week after injection; nausea; extreme breast pain and lower back pain for up to 3 months; fatigue that gets worse with every injection; jaundice and kidney damage; rage; mood swings and severe depression; loss of sex drive/life; very, very dry vagina | The idea of this drug seemed wonderful, the side effects have been horrible! I am now suffering from kidney damage and jaundice caused by long-term use. It is ridiculous that the literature on this drug says that this type of thing occurs in only 2% or less of the population taking this drug. Do not take it!!! | F | 34 | 13 months | 1/3/2010 | 1 | prostate cancer | I am writing this on behalf of my husband. this medication turned my once loving gental husband into Mr. Hyde the monster created by a Dr. thats only part of the nightmare we are ready for divorce court.the sweats, no libido,no erections, incontenence is increasing daily.our 2 growe up daughters want nothing to do with their father. our grankids heard him say he's going to kill our sons 2 baby kittens he is a monster and he demonstrates the behavior of someone suffering a phycosis hopefully he'll return to himself before it's too late | my husband was first injected with a 30 day dose. then a 90 day . last time a 6 month dose andit's been 9 months of sheer hell ......... | F | 51 | 300 days | 10/5/2009 | 1 | prior to ablation for endometriosis | severe moodiness - became so nasty. anxiety, tearfulness, so forgetful, lack of concentration, unable to cope with stress. Panic attacks, dizziness, headaches, leg pains, back pain, spotting, very sore breasts, exhausted, shakes, night sweats, gained weight, palpitations, insomnia, hair loss, tearful, cramps | I have never felt so unbalanced, out of control and incapable of coping with life as I have the past 2 weeks after having the first injection. I can't drive as i am so light headed and the slightest thing I panic. My husband thinks I have become possessed as I have been so moody and angry and irrational! I can't sleep properly and it has made my lower back and sciatica ( I have degenerative disc disease) so much worse I am popping so many pain killers to try to sleep. Everyone who knows me has commented on how I have turned from such a coper and bubbly person to such a wreck. Is it worth it I wonder but its too late now...........surgery in 2 weeks lets hope that work as I have never felt this unwell. | F | 41 | 15 days | 8/27/2009 | 1 | breast cancer | severe hot flushes day and night - sometimes up to 2 an hour during the night and about 10 during the day, depression, terrible headaches, insomnia, totally physically exhausted, aching all over, weight gain but loss of appetite, | My quality of life since starting on Zoladex has deterioriated significantly - I feel physically drained and haven't slept a night since I started it. I put on nearly a stone in weight in the first couple of weeks even though I didn't feel like eating and was living on one meal a day. The hot flushes are awful - sometimes more than 24 in a day and seem to be worse at night. My husband had to move to the spare room as I wasn't sleeping at all and so our physical relationship is under pressure too although my sex drive is not so bad as when I was on Tamoxifen for a year. Overall I'd much rather take my chances without this drug than the side effects when I'm on it. I have had other drugs prescribed to counteract the side effects but they have their own side effects which left me in a trance most of the time even though they helped the hot flushes. | F | 42 | 3 months | 7/4/2009 | 1 | prostate cancer | impotent hot flushes weight gain | do not take it | M | 61 | 3 days | 4/30/2009 | 1 | prostate cancer | Severe hot flashes - day & night, lasting 2 years after my last injection, weight gain on stomach, loss of mental acuity (none to spare), change in emotional reaction to stress and other situations, complete loss of libido, possible cause of loss of bone mass (I have some, don't know if it was preexisting). | This drug had the desired effect of reducing my PSA by about 90% prior to radiation, but at a significant cost to my my physical and emotional health. These side effects, for the most part, were not disclosed to me prior to treatment; I only learned they are directly attributable three years after treatment as a result of reading an article in the Globe and Mail. I do not think the people prescribing this drug understand the life altering effects it can have on your health, relationships and career. Waking up several times, every night, soaked in sweat affects every aspect of your life (on the other hand, having zero libido frees up some extra time for work, too bad you won't give a shit). I understand there are alternatives, and I would suggest men investigate them before accepting this treatment. I would also suggest, if you do decide to take this drug, that you have a blood test done so you know what your normal testosterone level is, so you will know afterwards when (if) you ha | M | 55 | 12 months | 3/4/2009 | 1 | Endometrial ablation | Terrifying headaches, fainting, joint pain so bad it was hard to text on on iPhone!! Sickness, shaking, unable to form a sentence, memory loss, had to think carefully before speaking, didn't stop the bleeding, liked the free boob job though when they weren't very tender. | Make sure you read the side effects, sickness is caused by the removal of calcium from bones hence joint pain. Bone density damage is irreversible. | F | | 1/28/2009 | 1 | postrate cancer | hot flashes chills fevor low blood presure weight loss loss of appetite | M | 74 | 6 months | 5/24/2008 | 1 | Endometriosis | Servere hot flushes, migrains, no sex drive, moody, loss of period. | I stopped taking Zoladex 2 1/2 years ago and if i knew back then what i know now i would have never trusted the doctor and gone the Zoladex i would have opted for the Surgery. 2 1/2 years on i still have no sex drive, No period, No fertility and im still moody.... DONT TRUST DOCTORS | F | 27 | 6 months | 4/28/2008 | 1 | Endometriosis | Hot Flashes, Irritability, Mood Swings, headaches on right side of head | POSSIBLE WARNING to THOSE WITH SEVERE MYOPIA....I had 4 eye surgeries as a child, as I have a very rare eye condition...while on this medication, I suffered a likely irreversible loss of central vision to my right eye. My Moscow opthalmologist commented that I was not the first woman on Zoladex or other type of hormone therapy to suffer this problem. This is a VERY POWERFUL drug...You have to make sure the benefits outweigh the potential side effects. | F | 40 | 3 months | 11/15/2007 | 1 | endrometreosis | hot flashes, severe joint and muscle pains - | I lasted 2 months then my doctor said we'd try something else. It's been 6 weeks since my last shot and still I can hardly walk, or even go to school because of the pain in my shoulder, hips, knees and ankles! | F | 23 | 60 days | 8/7/2007 | 1 | endiometriosis | sever joint & muscle pain 1 year after recieving it! Bad headaches, mood swings, short term memory loss, burning, tingling all over, dizziness, panic attacks, heart palpitations, chest pain - the list goes on! | TAKE AT YOUR OWN RISK! LOOK FOR ALTERNATIVES OR YOU WILL REGRET TAKING THIS POISON! | F | 39 | 1 years | 12/17/2005 | 2 | Endromerriosis | Really bad mood swings, irritable & depressed. | F | 29 | 6 months | 12/28/2012 | 2 | nauses headaches daily | I have had the injection once and will not be getting it again it has made my pain 10 times worse | F | 22 | 1 months 1 | 11/23/2012 | 2 | Endometriosis post-op cystectomy | Migraines daily, insomnia, loss of apitite, vomiting, crying,angry,depression, sweating, bad hot flushes all in month 1 i'm dreading the next 5 :( | I'm receiving this zoladex treatment after I had a 9cm chocolate cyst removed from my left ovary through laparotomy I'm hoping this suppresses the disease I never want to experience that pain again! | F | 21 | 6 months 3.6mg 1X M | 7/24/2012 | 2 | Endometriosis | Hot flushes, insomnia, mood swings, highly emotional, loss of libido, nausea, headaches, flu like symptoms. | F | 20 | 4 months | 7/22/2012 | 2 | Possible endometriosis | Insomnia, nausea, memory loss, hot flushes | I was asked to try Zoladx injections by the gynaecologist as he suspects I have endo. I have all the symptoms however only have small adhesions on the ligaments at the bottom of the uterus. There is no other sign of the endo. I tried tri-cycling the contraceptive pill which worked for a few months as I didn't experience pain mid-cycle but then the usual pains and swelling returned and the last period was that bad that I was about to ask for a hysterectomy! I had 1 x Zoladex injection and although there was no endo pain the side effects were horrendous. I am seeing the gynaecologist privately and he had written to my GP to ask that they perform the remaining injections. GP told me that they would use Prostap instead of Zoladex and the 2nd injection was therefore Prostap. Since then I have experienced no pain whatsoever, the insomnia and nausea have disappeared and I only occasionally have a hot flush. I saw the gynaecologist a couple of weeks after the 3rd injection (so 2nd Prostap) and he is really pleased that I am not experiencing pain and has suggested I continue for up to 18 months. I will now start to take some form of add back therapy to stop me fully going into the menopause. I am also going to take calcium vitamins. All in all I am happy on the Prostap but suffered on the Zoladex. | F | 33 | 1 months 3.6mg 1X M | 7/22/2011 | 2 | Fibroids | Hot flashes, migraines, short term memory loss, moodiness, irritability | I took Zoladex for 4 months in an attempt to shrink very large fibroids. Largest of 4 fibroids was 10 cm; my entire uterus was involved, some of the fibroids were calcified. My gynecologist was optimistic about shrinking them enough to do a vaginal hysterectomy. Initially, the fibroids seem to shrink a little, however, by the 3rd shot, they started to grow at a rapid rate. A little after the 4th shot, I had a total abdominal hysterectomy; the fibroids had grown significantly larger. Even though the result was disappointing for me, I'm glad that we tried this course of treatment. | F | 46 | 4 months 3.6mg 1X M | 4/18/2011 | 2 | endo | my experience with zoladex have been good and bad. after my first implan i hardly had any bleeding and pain which was fantastic. ive bled sooo heavy and lost lots of large clots and am always aneamic so having the bleeding and pain stopped was just fantastic. then it all went downhill from my 2nd implant. the headaches are unbearable, hot sweats, extreme anxiety, mood swing, crying, nervousness, lack of concentration, memory loss, chronic joint pain and then yesterday i collapsed at home and my husband rang an ambulance. my blood pressure was 230/130, which the paramedic said was life threatening. i also had a temperature. the a and e doctor said it was down to the zoladex. im supposed to have my 3rd implant this friday and my family dont want me to have it done. its a catch 22 situation, if i dont have it then the pain and bleeding will start but if i do have it then im so scared of the side effects as its got worse with each one. my only hope for getting my life back is for my specia | F | 38 | 2 months 1X M | 11/16/2010 | 2 | Breast CA | severe hot flashes( about 1 an hr) trouble sleeping from hot flashes,nausea if hot flashes are after I eat, crying alot,kinda feel spacey (not sure if this is from hot flashes and lack of a good nights sleep)joint and muscle pain which is getting worse and making me feel like an old lady, trouble walking, pain in knees and hips,really bad shoulder and back pain (worse at the end of the day)fatique and sad alot of the time from all these side effects which are making me feel crappy and cranky. | My doctor gave me a mild antidepressant to get rid of the hot flashes but I have not taken them as I don't like taking all these drugs and am afraid that another drug will just have more side effects to deal with. He recommended accupunture which I am going to try in a few weeks (already talked to the doctor who does the accupuncture and she said she has had success with it for hot flashes..so wish me luck or its going to be a long hot summer). As far as the muscle and joint pain, this better go away soon. The accupunture doctor said she could probably help with that as well if it persists. Wish there was a better way to reduce the risk of breast ca returning,not sure if I will be able to take this for the entire time recommended if I continue to feel like this. | F | 49 | 4 months 1X M | 5/30/2010 | 2 | endometriosis | sweats, shakes, back pain, abdominal pain, pain down my legs, mood swings, bleeding, temp | i have been put on zoladex 3.6mg and put on lival 2.5mg for my flushes and sweats and the rest im new to this drug and since having the implant i am now bleeding heavy serious pain in my back and legs even pain killers anit taking it away | F | 24 | 5 days 3.6mg 1X M | 4/5/2010 | 2 | endometriosis and adhesions | Extreme tiredness, forgetfulness, mood swings, aching body, legs feel filled with concrete when i walk, head filled with cotton wool fuzzy moments,period began heavy,bowel disturbance,craving sweet things | Have been taking this exactly one month with Tibolone Addback HRT to i presume balance my hormones as Zoladex shuts down my ovaries. First noticable side effect was extreme tiredness, everyday tasks seem even harder and more exhausting, fuzzy head and heavy achey feeling in my body generally. Feel like i want to become a hermit, aware of sudden flare ups of anger or emotion followed by exhaustion. Had to give this a go, hysterectomy next option but endometriosis has spread into my pelvis around belly button as well as right ovary which was recently burnt away from bowel fallopian tube stump (previously removed in surgery) had adhered to surrounding organs. Pinching is constant. Previous surgery worked for very short time relief immense but it returned with a vengence. Convinced it has readhered to ovary. Despite zoladex pinching very evident one month into injections and feel a bit sick at times as well as other symptoms but determined to give it a go along with tibolone. Whole thing is really scarey and information is sparse even GPs have to look it up, nurse administring it claims she only ever gives it to men with prostate cancer! Im in the hands of the gods,nhs and in the meantime i just sit back try to live with the side effects and wonder where this is all going to end up, i have to have hope! (ps confession not been able to give up some smoking and the odd drink im so stressed i need a prop but taking supplements vit c, eating cheese (although a veggie that eats | F | 51 | 30 days 1X M | 3/31/2010 | 2 | Breast Cancer stage 3, HER2/Es + | Continues eye infection,headaches, nausea, extreme abdominal pain, diaree, fever & chills, hot flushes, bone pain, back pain, no sleep, no sexual desire - fear of sex because of the pain of vaginal dryness!!, mood swings, depression and I can still go on!!! | I have been taking Zoladex now for almost 2 years - just had my 7th injection and it was like hitting a brick wall. Side Effects became so bad that I felt like I was dying. My oncologist decided now to stop Zoladex and to start Tamoxifen, luckily then when I do get very sick again I can stop treatment not like now I have to wait for the Zoladex to work out of my system (another 3-5 months). I sometimes feel that I would rather take my chances with the cancer than with these drugs... Feel worse now that I did when I was on 8 months of chemo.... | F | 33 | 20 months | 11/26/2009 | 2 | Endometriosis | Weight gain, sever hot flushes, tender breasts. | I am on my 4th and last injection as I am having surgery in a few days. My ovary and tube are stuck to the back of my pelvis due to the endo and I was given this to stop my periods while waiting for my surgery. Although my periods have stopped, my pain has not changed at all (constant pulling pain, not endo flare ups). The hot flushes in the 1st 3 months were so severe that I had to constantly have a fan on during the night and they made me feel sick. Also I have put on around a stone and a half since starting it even though i'm not eating as much. | F | 28 | 4 months | 10/12/2009 | 2 | endometrial ablation | hot flushes, nausia, dry mouth, tiredness, severe bleeding. nausia, dry mouth, severe bleeding, sore booobs,hot flushes, back and pelvic pain, tiredness,insomnia. | had the implant with local anesthetic so painless, expected and was told no bleeding, flooding and extremely painful. | F | 40 | 1 weeks | 10/9/2009 | 2 | Secondary Breast Cancer | Severe hot and cold flushes, shivering, sweating, Vomiting, nausea, anxious & panicky, loss of appetite. | Im due to have my 5th Z in a couple of days but after the last month or so I have now decided that Im just not gonna take this poison any more. I have felt way more dreadful than evan the chemo (taxotere) made me feel over the last week or so. The hot & cold sweats have been relentless and Ive vomited on & off since i started it - the last week in particular has been awful - i cant keep food down due to the constant vomiting - im sweating so much im having to change my clothes about a dozen times a day !! | F | 36 | 5 months | 10/19/2008 | 2 | endometriosis | hot flushes , blured vision, emotional, worse pain in tummy , loss os sex drive, shaking,headaches, sever bleeding, dizzy and faintness.rattyness. | im 21 i was told i had endo at 20yrs old. am on my 5th dose of zoladex and i have found it has not helped me at all, i have more pain than normal and feel worse than when i went to the docs . having the inkections are really painfull. i have only got 1 dose left but i know i will have to go through other treatments as im still the same. i would advise anyone who is going to have this ttreatment to think it through as its not 100% correct for everyone | F | 21 | 6 months | 10/13/2008 | 2 | metastatic breast cancer | hot flushes, sweating, insomnia, vomiting | not helping malignant effusion | F | 44 | 3 months | 11/5/2007 | 3 | Endometriosis | Headache, nausea, vomiting, feeling unwell, dizziness, upset stomach | Had Laparoscopy in Nov 2012 and some endo removed, mirena fitted, but had bad side effects from mirena. Gyno suggested zoladex as still in pain. 1st injection increased pain for about 2 weeks, some side effects but not to bad, week 3-4 pain most days but nothing i couldn't cope with. had 2nd injection 1 week ago OMG. side effects within 2 hours of injection, severe pain, the next day more pain, vomiting, bad head to the point where i had to go to bed, spent the next two days mostly in bed ( not great when you have kids) still got bad head, dizziness, cheeks tingling and warm, nausea and my stomach is also upset.NO WEIGHT GAIN, as i eat very healthy and exercise loads when I'm up to it. When I train I am pain free, due to your body releasing endorphins, that combined with meditation keep my mind and body strong. | F | 35 | 6 months 3.6mg 1X M | 3/19/2013 | 3 | currently taking for endemetriosis | I have had it fitted 4 1 week currently experiencing suicidal thoughts depression hot flushes nausea tiredness and dizzyness doc says it shouldn't work just yet but it obviously is and I am worried that it says only 2 take for 6months max yet I'm on it for 9months!? | F | 20 | 9 months 30mg | 2/14/2013 | 3 | Fibroids to reduce size | Hot flashes about every 30-40 minutes mostly in evening . Night sweats. Inability to sleep due to being boiled or freezing. Severe blinding headache on waking . Dry skin . Very tired. Foggy brain. Feeling fed up. | F | 47 | 3 months | 1/16/2013 | 3 | endometriosis (after Laparoscopy) | Tiredness, hot flushes, disrupted sleep, slight moodswings | F | 29 | 6 months | 11/2/2012 | 3 | Uterine Fibroids | Hot flushes but diminishing, restless legs, dizzy spells, pins and needles and numbness in hands (not known if this is result of injections), generally tired | Have now had five injections - one more to go. Have large fibroids (eight month pregnant uterus). Even though side effects have been difficult it has been better than constant flooding (ended up in hospital twice) and pain as I had not reached menopause (at 57). Hoping menopause will kick in after finishing treatment otherwise it will mean a sub-total hysterectomy. Fibroids appear to be shrinking a little but not a great deal and bleeding stopped. | F | 57 | 5 months 3.6 mg 1X D | 10/16/2012 History | 3 | awaiting hysterectomy | Just had my 2nd injection yesterday, feel awful, disturbed sleep, night sweats, cannot concentrates, very emotional. Roll on the next one !!!!! | F | 38 | 1 days | 9/24/2012 | 3 | Endometriosis | Hot flushes, night sweats, increased pulse rate, lower back pain, lethargy, insomnia. | Although I've been bleeding for 2 weeks (not heavily), I haven't had the usual agony associated with Endo, so am willing to cope with the side effects if it works!! | F | 34 | 5 weeks 1X O | 9/4/2012 | 3 | Prostate Cancer stage 3 | Was diagnosed with Prostate Cancer stage 3, and prescribed with hormone treatment to be followed by Radiation therapy, either Brachy or beam therapy. Reading other peoples side effects just wanted to say I am feeling lucky | So far side effects are general tiredness, and not sure if my aching joints are Zoladex related as I also have polymyalgi Rheumatica and RA being treated with methotrexate. Before starting Zoladex treatment my wife checked potential side effects and changed my diet as follows; Now eat only Soya bread (in UK we get Burgen's Soya & Linseed Loaf), to date no hot flushes, and minimal mood swings, my wife swears by Soya for all menapausal symptoms, she used Alpro Soya milk in cereal occasionally. worth trying if it eases discomfort of hot flushes. | M | 72 | 3 weeks 10.8 1X O | 7/23/2012 | 3 | endometriosis | Hot flushes, migraines, nausea, mood swings, sore joints. | F | 28 | 6 months 3? | 5/12/2012 | 3 | endometriosis | Nausea,moody,dizziness,terrible headache,flushes,sweating a lot | F | 28 | 9 months 80mg | 5/10/2012 | 3 | Endometriosis | Migrains , sick feeling in my stomach causing loss of appetite, disgusting skin very dry and acne, joint pain, spotting, cramps ! Very moody, cry over the stupidest things that usually I wouldn't even blink at, depressed feeling started kicking in after the 3rd dose. I've already had operations to remove it but that was less then a year ago and it's already worse then the start. I guess it's helping with no periods but definently thrown in the deep end hoping for the best results possible so this was worth it | F | 21 | 4 months | 5/7/2012 | 3 | severe endometriosis, pre surgery | On the 4th day after implant each month suddenly felt dreadful with chills, severe nausea and loss of appetite lasting 48hrs with some abdominal and back pain. First week severe headaches, following weeks mild occasional headaches. Hot flushes. Waking up throughout night feeling hot. Dry lips, skin and hair. UTI. Joint aches, mostly in shoulders. Apathy and depression. Zero libido. | Painless but heavy bleeding for 1 week after zoladex was implanted. On positive note no period, no endo pain. Will find out how successful zoladex treatment was when I have laparoscopy after three months of supression. Doubt I would agree to use this medication again due to side effects. | F | 31 | 2 months 1X M | 5/2/2012 | 3 | elevated PSA | Following radiation and protstatectomy put on Zoladex. Hot flashes (20 per day),total loss of libido and personality changes (not for the better) and joint pain ensued. Vowed I would rather die than do it again, but when presented with that alternative last week when PSA rose to 5.8 have reluctantly decided to resume Zoladex injections. | Like so many others have commented, while the PSA will go down and the metastased cancer areas will no doubt stop growing, perhaps even shrink, the side effects for some are very disturbing. Having been off Zoladex for 5 years and vowing never to go on it again, there are no other options if you wish to keep living. Perhaps the antidepressents I have been prescribed will help the dreaded side effects. As a male I certainly sympathize will all the ladies suffering from menopause and the hot flash syndrome. 20 of those attacks a day and living in perspiration at night along with the mood swings are no treat. An alternative to this drug without so many side effects would be most welcome. For any man reading this post, if you need the drug and suffer afterward you are not alone, hang in and hopefully after a few injections (I had 3) you can go off for a few years before facing the ordeal again. I must mention that I have an older (80 yr) male friend who has taken Zoladex with relatively few side effects so there is hope your personal experience will be better. | M | 69 | 9 months 10.8 1X O | 2/12/2012 | 3 | endometriosis | feel,weak, nauseated, vomiting, and tired constanly. hot flashes and joint pain.It has only been one month 5 more to go. | hope to see improvement. | F | 30 | 6 months ??? 1X M | 11/22/2011 | 3 | pre TCRE | emotional and irritable after 1st dose, with one day of whole body pain.....after 2nd...unbearable bone pain,vomiting, vaginal dryness/soreness,permanent headache, wheezing and generally feeling like im going to die. | Thankfully i dont have to have another of these nasty implants, but if the surgery following this drug is successful i would say that however horrendous it has been, it will be a small price to pay to get my life back. :) | F | 40 | 2 months 3.6mg 1X M | 10/30/2011 | 3 | Adenomyosis | Terrible Headaches, Whizzing fuzzy head. Hot flushes. Extreme fatigue. Weight gain. dizzyness. Very emotional and tired during week 4 of each injection. Dry skin too. | Have possible Adenomyosis which is difficult to diagnose. Prescribed 3 months zoladex to confirm diagnosis before hysterectomy. Adenomyosis symptoms disappeared by week 2 so Zoladex did work well. However side effects so bad Doctor didn't do 3rd injection as Zoladex had already shown what he needed & I couldn't bear it anymore. | F | 40 | 2 months 1X M | 7/17/2011 | 3 | endometrosis | Memory loss confusion horrendous hot flushes and night sweats swollen feet and ankles joint pain numb toes and feet.Weight gain changes in hair | I had a hysterectomy 14 years and my endometrosis has returned and i have cysts on my ovary i would not take zoladex again due to hot flushes and night sweats i have not had more than 30 minutes sleep at one time for 4 months. I have hot flushes every 30 minutes this is affecting my work and family life .I have aching joints swollen ankles and feet nunb toes i can hardly get down the stair in the morning due to joint pain in my feet and ankles. What have i done to myself i have now to go for a bone scan due to bone thinning caused by zoladex i wish i had pushed to have my ovaries removed. Cant wait to stop Zoladex and get my life back | F | 47 | 5 months 3mg 1X M | 6/19/2011 | 3 | Stage 2/3 Endometriosis | Hot flashes, more emotional/irritable | Ever since I was 12, I have been having horrible periods. After being on Depo Provera for a year, I started bleeding for two months straight and I became severely anemic. I was put on birth control pills along with Depo then taken off Depo and put on a pill with a higher dosage. Long story short, I finally saw an OB-GYN and the next day I got surgery to diagnose Endometriosis. I am 4 shots into the 6 shot Zoladex treatment. The only time I bled was when I first started on Zoladex due to estrogen withdrawal. I haven't noticed a change in my endo symptoms because I'm not bleeding (I didn't bleed on high dose BC pills either). After the 6 months are over, I am going to go back on Depo. If severe cramps and heavy bleeding return, I will have another surgery to burn off the lesions. I have hot flashes all day long and very bad ones at night as well. I am from the heat and have sweat more in the last 3 months than I have my whole life. I am a lot more emotional and at times when I get frustrated I just want to cry and punch something. | F | 19 | 3 months 3.6mg 1X M | 5/19/2011 | 3 | Gyno problems | hot flushes, headaches, migraines, full body sweats, back aches, UTI, blocked batholin glands, mid to sever depression | I had it for gyno pains, got 1 period after injection that lasted for 18 days very heavy, flushes and sweats very extreme, mild depression, turn into sever depression, constant headaches turning in migraines by the end of day, 2nd and 3rd month no period yay!!. Didnt stop infections associated with my 1st period. But on the up pain improvement was remarkable, I was in sever pain for over 6 months and within 2.5 weeks pain improved by 80% and now by 95% I would recommend for the pain but as for other side effects will never take zoladex again, i went from being bed ridden with pain, to being bed ridden with sever depression, really not worth it when you work full time and have 4 children to raise on your own. | F | 35 | 90 days 10.8mg 1X O | 5/2/2011 |