Drug Ratings for ZOLADEXAverage Rating: 3.1 (167 Ratings)
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Results are sorted by Satisfaction from highest to lowest Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 |
| RATING | REASON | SIDE EFFECTS FOR ZOLADEX | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 5 | Endo | Initial mood swings, emotional , hot flushes, night sweats, some nauseous headaches | F | 47 | 6 months 3.6 | 2/7/2013 | 5 | Prostate cancer | No libido,hazy thinking,lack of concentration,hot flushes,mood swings. | The last two injections have been really painful.I seem to have become sensitive to the rather large needle.Bruising at the site (tummy) and quite sore for a few days.No problems previously.Same doctor same everything else.Will have a local in future. | M | 64 | 2 years 3.6 1X M | 10/9/2012 | 5 | Breast Cancer | Weight Gain and Hot Flushes | Was on Tamoxifen and Zoladex - but hopeless with a pill a day, so only on Zoladex monthly injections now. Doing my injection myself each month is a nice reminder that I AM a survivor and that I'm grateful for this medicine to put me in a better position further on down the track. Zoladex for me is easy - no fuss. And I'm so grateful I don't have periods anymore!! Just gotta remember to get out there and exercise more to combat the weight gain. | F | 41 | 18 months 3.6mg 1X M | 2/15/2012 | 5 | Endo & Chocolate Cysts | Migraines, Hot Flushes, Night Sweats & Joint Ache in the latter months of taking it. | F | 37 | 10 months 1xM | 1/21/2012 | 5 | Endometriosis | Headaches (only the first week or so), hot flushes, night sweats, slight forgetfulness | So far so good! Having hot flushes and night sweats is much better than being in pain - though I had the Zoladex LA 10.8mg injection right after my laparoscopy to remove chocolate cysts on my ovaries, so maybe the surgery helped with the pain too. | F | 32 | 3 months 10.8mg 1X O | 8/12/2011 | 5 | Endometriosis | Mild headaches, Hot Flushes | Zoladex has been amazing. Was is severe pain before and on many painkillers, am now pain free and have started on HRT and now have no side effects. | F | 16 | 6 months 3.6 1X M | 9/1/2010 | 5 | Fibroids | Hot flushes, nausea, cold sweats, insomnia, lack of libido, dry vagina | Treated for 6 months to shrink and firm up extremely large fibroids. Worst effect was nausea and hot flushes, especially during the night. Also, I seemed to be always tired and fuzzy due to lack of sleep. Result excellent as fibroids shrunk enough to be safely removed. It was worth 6 months of feeling unwell to retain my uterus. I also made an effort to go to the gym to keep up my fitness and help bone strength. Difficult at times but again, worth the effort. | F | 35 | 6 months 1X M | 7/25/2010 | 5 | endometriosis | night sweats,headaches,lack of concentration,weight gain,puffy face,aches in joints.On the plus side,sex drive back to normal. | my consultant decided to try me on zoladex to see if a hysterectomy would be suitable and so far so good.The benefits far outweigh the side effects and i feel almost back to normal.I have another 2 months of injections to get.I have been taking livial tibolone hrt to combat menopausal symptoms.I am very happy with zoladex. | F | 32 | 1 months 3.6mg 1X M | 7/22/2010 | 5 | Prostate cancer | Loss of libido, hot flushes, impotence, gaining weight, tiredness and lack of concentration. | I get injected every 12 weeks. After taking zoladex PSA down to 0.1 from 7.0 Side effects a bit of a nuisance but it seems to keep PSA down. | M | 54 | 18 months 1X O | 5/21/2010 | 5 | Severe endometriosis | Initially hot flushes, vaginal dryness etc. However once I started taking Kliovance (HRT) it counteracted all side effects. Bone density scan was also ok. | Fantastic. Would stay on it forever. Gave me back a normal life without any pain. | F | 33 | 2 years 3.6 1X M | 4/15/2010 | 5 | endometriosis | Night sweats | I can honestly say that having this implant is the best thing thats happened to me, apart from night sweats, all my pain goes while using it, weight decreases and general wellbeing is excellent. Ive had two implants in, last one in november, and the decision has been made to have two more as symptoms are returning. These will probably be my last as it can decrease bone density so I have to take oestregen while using it. I had no other problems at all while using it and am eternally grateful for doctors introducing me to it!! Anyone wanting to email me is more than welcome, I havent actually spoken to anyone properly with endometriosis, would be interesting to find out other peoples symptoms etc. | F | 29 | 6 months 10.8 1X O | 4/12/2010 | 5 | Endometriosis (severe -post lap) | Hot flushes, Sweats, sleepless nights,bleeding in 1st month, slightly emotional, lowered sex drive (was given hrt add-back treatment after 3rd month when these side effects disappeared!). | Absolutely amazing...to have suffered for 18/19years with such intense pain to have it disappear was/is amazing! the side effects I have listed are more than welcome compared to the pain (as many endo sufferers can agree with). I take the hrt to counteracts the menopausal side effects so now I am perfectly balanced - unfortunate we can only take this medicated for a short limited amount of time! | F | 33 | 4 months | 12/10/2009 | 5 | Endometriosis Stage 3 | The occasional hot flash | I am on my second month of zoladex and have no pain other than during intercourse which I am hoping will decrease over time. I have had one laparoscopy + treatment to remove some of the endometriosis however I still have a deposit on the recto-vaginal septum and appendix which will (fingers crossed) shrink with the zoladex treatment. All in all, I am happy with this treatment. | F | 33 | 35 days | 11/30/2009 | 5 | Post-breast cancer treatment | Hot flashes | I began monthly Zoladex injections following chemo, bi-lateral mastectomy and radiation. I also take Tamoxifen daily. My main complaint was hot flashes, in particular at night, that were causing sleep loss. My doctor put me on a very small dose of Effexor, which I take every morning and it's worked wonderfully. I do still occasionally have a hot flash at night, but they're rare and not as bad as they were. | F | 45 | 8 months | 11/14/2009 | 5 | Protate cancer | Pains in the joints which seem to be getting worse,some nights I wake up after two hours sleep and can feel myself getting hotter and hotter aand have to go and lie down in a cool room.I seem to be muscularly weaker in the legs, perhaps this is just my age. My weight around the middle particularly has increased and I get swollen feet and ankles. The joint pains are the worst feature along with swollen feet | I have very understanding doctor, she has said I may see the urologist any time I wish to. My only fear was incontinence, this did not happen. I felt quite rough initially, but it has had a dramatic effect on my pSA, going from something like 32 to 1.8. I would rather live and am glad I opted for it. | M | 76 | 270 days | 10/11/2009 | 5 | IVF - Down regulation | I suffered very few side effects, other than a very mild headache in the evenings and a slight feeling of tiredness. | As someone who sneezes a lot I couldn't take the nasal spray down regulation drugs so was given a single injection of Zoladex. The drug worked as it was supposed to and my down regulation was a success. | F | 31 | 28 days | 3/18/2009 | 5 | Endometriosis | UPDATE: Hot Flashes, Bones Cracking, VERY slight joint pain | UPDATE:Had my 3rd injection the day before Turkey Day. Started a different OTC joint supplement and that has 'cured' the severe joint pain I was experiencing. Hot flashes have calmed down and are more managable because the cold weather has arrive!. My bones crack quite frequently but it doesnt hurt. NO mood swings. NO weight gain. This medicine is pretty darn close to PERFECT! | F | 26 | 58 days | 11/28/2008 | 5 | Endometriosis & Adenomyosis | headaches and migraine, severe fatigue/tiredness, dizziness, sweating, hot flushes, joint aches, hair thinning, greasy skin and hair, acne, poor temperature control, anxiety,occasional pains (poss linked to endometriosis rather than drug!) | Zoladex has worked well in relieving my severe pain which was debilitating. For me the side effects are better than having pain and a change in add-back therapy is improving some of these symptoms. | F | 26 | 7 months | 4/21/2008 | 5 | endometriosis | I found Zoladex to be brilliant. My endo pain went within days of the first injection. I had no mood swings and felt really well on it. I would definately recommend it. | I did get hot flushes, slight weight gain and my skin was occasionally spotty. | F | 40 | 9 months | 2/15/2008 | 5 | endometriosis | Hot flushes, vaginal dryness, lots of tears, panic, jitters - but soooo much better than the pain of the endometriosis - its saved my life (literally!!) | I had to have a kidney removed and a ureteric reimplantation as a result of the most severe endometriosis my surgeion had ever seen - oh joy! took 10 months of zoladex and its been such a relief - just petrified of coming off now!!! | F | 30 | 10 months | 12/3/2007 | 5 | endometriosis | Mainly hot flushes. They don't last very long and I don't sweat or turn noticeably red. Sometimes I wake up at night and have to push blankets off. Vaginal dryness. I also seem to be thirstier than usual and going to the loo more often. I don't know if this is related to the zoladex or the fact I am exercising a bit more to try to build up my bone density. | It has helped immensely with my endometriosis pain. The hot flushes are sometimes a bit annoying, but they're nothing compared to the endo! The hot flushes can sometimes be great in cold weather! I wish I could stay on it forever but I'm worried about osteoperosis | F | 34 | 5 months | 4/14/2007 | 5 | uterine fibroids | hot flushes, lethargy, reduced libido, bruising and irritation at injection site. | not a pleasant drug to take, but enabled me to get back to a normal life without having to have a hystorectomy. | F | 38 | 2 years | 2/15/2006 | 5 | Breast Cancer Bone Metastasis | Severe flu-like symptoms after first infusion, decreased each month until no noticable reaction | Drink lots of water to help minimize reaction and rest, it will get better after time | F | 38 | 16 months | 9/5/2005 | 4 | Treatment of Fibroids pre Surgery | I have been on Zoladex injections for 3 months for the treatment of Fibroids pre surgery. I was supposed to have one more but i have been told by the Doctor that it isnt required as the Operation date is now set! After reading some peoples experiences i just wanted to add my own as i found other peoples reviews helpful. My side-effects arent that bad so far, most of them are a mild inconvenience. I found that the weight gain can be controlled if you exercise regulary and dont over induge, especially if you are feeling low or emotional. Exercise aslo made me feel alot better and helped me when i couldnt sleep. Im a person that loves my glass of wine and my daily coffee, so i didnt cut out alcohol nor coffee, but my side effects arent that bad still indulging on these guilty pleasures. Im not sure if the medicine has worked yet as im due for surgery in 3 weeks time. I do feel that the pressure on my bladder from the fibroid has reduced as i dont feel the need to go to the loo that often now. And no more heavy, painfull cramping periods, so in that respect it is working!. Hope this helps anyone who has fibroids or is taking the Zoladex 28 day injections!, will update the post once ive had surgery! | F | 32 | 90 days 3.6mg 1X M | 4/16/2013 History | 4 | Prostate Cancer | Worst side effect is erectile dysfunction, shrunken testicles and penis. Next comes fatigue and general tiredness. Next is loss of memory and lack of mental energy. Restless sleep and hot flashes, muscle weakness, paticularly in legs, 16 pounds weight gain. Inceased appetite for food. These are the main effects. Otherwise I am happy and glad to be alive. | 10.8mg every 3 months. | M | 64 | 2 days 10.8mg 1X O | 1/15/2013 | 4 | Intravascular leiomyomatosis | Taken with Letrozole massive tumour shrinkage (myomas/fibroid in vascular system). Chronic insomnia, problems with immediate short-term memory, zero libido, severe hot flushes, joint pain & stiffness, muscle spasm in hands/fingers, lethargy & low mood. DHEA, calcium / magnesium, vit D, fish oil DHA helped. Avoid wheat and beer, alcohol generally will make symptoms worse. Now stopped taking and trying ulipristal acetate (specific to fibroids only) plus calcium-d-glucarate, DIM, matcha green tea & phytoestrogens: red clover, black cohosh ie SERMS & SPRMs, to flush out excess estrogen & progesterone. Be careful before stopping Zoladex. It works. Get your disease stabilised before trying alternatives and always involve your clinicians, even if they don't agree with your choices they can offer blood tests & imaging to check disease remission or progression as you try something else. Btw, one month off Zoladex side effects remain even though it can take as little as 14 days to flush from system, my guess is that it can take much longer! | F | 40 | 2 years 3.6mg | 1/4/2013 | 4 | Endometriosis | Hot flushes, night sweats, tiredness, bowel issues, mood swings. | As someone who rarely sweats, the night sweats and hot flushes were the hardest part of this treatment. The last 6 months being endo pain free has been amazing to have a "normal" life - whether this treatment has helped long term, only time will tell! | F | 26 | 6 months 1X M | 11/6/2012 | 4 | endometriosus/cysts on ovaries | After 17 years of endo pain.10 surgeries a radical hysterectomy leaving the ovaries behind.I had surgery last november and two weeks after I had a cyst that bleeds into itself every cycle.I was having pain ALL the time and it was interfering with work my social life.Upon last admission with regular morphine every hour over two days Zoladex was suggested to which I had on discharge.I have now been on Zoladex for three months and due to start my first quarterly injection.I have to date had NO pain.However my side affects are brutal.Depression nausia sleeplessness hot flashes and terrible debilatating bone aches especially between my hips and knees.It's so severe at times I have to take DHC to combat it.I will admit that this is NOTHING compared to the pain I dealt with daily and the severe cycle pain with the cysts so I can say that although the side affects are strong it's liveable. | F | 33 | 3 months 3.6 mgs 1X M | 11/6/2012 | 4 | Endometriosis | hair loss, a heavy hair loss!!! acne, mood swings, hot flushes, bone pain, osteoporosis. | F | 25 | 6 months | 10/31/2012 | 4 | Endo/Adenomyosis | Extreme endo pain, bleeding and moods in first month. Then felt really well, no pain, no bleeding. Now at 5th injection have hot flushes, night sweats, painful bones in feet, extreme tiredness and nausea/flu like symptoms. Am starting counselling too as had to come off HRT due to it feeding endo, and feel very down, crying, etc. | I will be on this until a hopeful total hysterectomy with oavary removal. | F | 37 | 5 months 3.6mg 1X M | 6/24/2012 | 4 | Prostate Cancer | Weight gain, headaches, flashes, zero libido, joint pain, lack of stamina, some mood swings but overall not that bad. Took an injection every 3 months | Prior to being diagnosed I had started my journey towards becoming a vegan. When I gave up all dairy, I dropped 24 lbs in 4 weeks. My oncologist was concerned that I was still losing weight while on another drug Luprilyde (I think). Well, I don't eat meat, chicken or any dairy but ballooned back all the weight. After reading this site, I finally understand my 2 year old headache. The joint aches and pains; muscle mass loss, flashes and zero libido are all right up there with my other fellow PC buddies. My PSA was 15.5 and Gleason score was at 10. According to all the tests, my PC had not yet metastasized. My treatment was HDR Brachy Therapy followed by 5 weeks of daily LDR radiation. My PSA has been at <0.01 for over a year and I just had my last injection. We don't know what's in store for me but time will tell. Hopefully, I'll have a lot of "time to tell". To say that this drug saved my life would be an understatement. I wish I had seen more of the side effects sooner but I guess doctors will tell you the bare minimum to curtail any psychosomatic symptoms through the power of suggestion. | M | 60 | 2 years 30 MG 1X O | 6/13/2012 | 4 | PROSTATE CANCER | The Zoladex as a medication works fine; I've had it over 17 years whenever my PSA exceeds 4 along with Casodex (Prevents flare) 6 times; 5 times I sat in a chair and the RN grabed abdominal flesh and shot the slow 12 week release Zoladex under my skin. THIS LAST TIME THE RN ORDERED ME TO LIE FLAT ON MY BACK IN A BED TELLING ME IT WOULD BE EASIER FOR HER TO ADMINISTER AND SHE SHOT IT INTO MY ABDOMINAL CAVITY AND LACERATED A MAJOR ARTERY CAUSING MASSIVE HEMORRHAGING WHICH I ESTIMATE ABOUT 4 PINTS OF BLOOD INTO MY ABDOMINAL CAVITY; THEY DIDN'T SIPHON AND TOLD ME IT WAS BEST TO BE NATURALLY ABSORBED AND THIS IS CAUSING ME LONG LASTING PROBLEMS. HOSPITAL IS IN DENIAL FIRST TELLING ME IS WAS A MEDICATION REACTION AND THEN TELLING ME IT WAS THE FAULT OF THE SYRINGE. ASTRA ZENECA SAID THEY WOULD INVESTIGATE AND NOTIFY THE FDA AND DIDN'T SO I FILED REPORT WITH FDA AND WILL HAVE LEGAL ACTION AGAINST ALL PARTIES. | I noted in FDA files someone in 1999 had colon and intestines lacerated when Zoladex was injected. Has anyone else had laceration when Zoladex administered, if so do contact me! | M | 79 | 1X D | 4/20/2012 | 4 | Endometriosis & Adenomyosis | F | 30 | 3.6mg 1X M | 4/6/2012 History | 4 | Endometriosis | Terrible headache after first injection, lasted 2 weeks. Then slight headache in the 24hrs after each injection. Dry mouth, dry skin, complete lack of libido, painful intercourse, lost weight (am slight anyway so this wasn't good), hot flushes after month 2, terrible mood swings after 3rd month - completely emotional and unreasonable. Month 5 now developing bone pain and exhaustion. | No periods, no bleeding, no bloating, no endo pain. Felt generally very well until month 3 when side effects kicked in.However my endo pain is non-existent and I am grateful for that. One more injection to go... | F | 40 | 5 months 3.6mg impl 1X M | 3/2/2012 | 4 | Breast cancer, oestrogen positive | Hot flushes , low sex libido , joint pain , mood swings ! | I get this injection every 28 days and take femara (used to be tamoxifen first 4 years) every day . It is hard sometimes but the alternative is harder . I want to live ! | F | 44 | 10 years 3.6mg 1X M | 2/17/2012 | 4 | Recovering from Endometriosis | Night sweats / hot flushes, constipation, headaches, fatigue, moodiness | Had a cyst removed from my ovary & severe endo removed. Post-surgery - Im well into month 2 of Zoladex. Initially I had nausea but this could have been the onset of my first period which arrived a week after my first shot! Pain was still there but far less than pre-surgery. Night sweats started 2 weeks after 1st shot & now into 2nd shot Im having hot flushes during the day too. Headaches regularly & constipation plague me too. Looking forward to my last shot in 4 months!! | F | 33 | 6 months 3.6mg 1X M | 10/22/2011 | 4 | Possible Endometriosis | Side effects: Hot flushes (daily and nightly) Occasional headache (never used to have them before) Brain "fog" Interrupted sleep (sometimes due to night sweats) Feeling over emotional | Doctor is trialling me on Zoladex to try get a diagnosis as to whether it is Endo or not. It's been the best 3 months of my life for years. No periods at all - it's been the best break ever! I used to get severe painful periods that lasted 3-4 weeks in full swing which meant I was off work most of the time. I've had a full 3 months in work and it's been fantastic to be back properly. Yes the hot flushes are awful and some of the other side effects but compared to what I was experiencing before it is absolutely worth it - hands down. I can't rate it as a 5 as I'm not "cured" yet, going back in a couple of weeks to see if I'm going to stay on Zoladex for a few more months (fingers crossed) and what they'll do next. Am a bit worried about the whole "bone density" thing but I've got freakishly strong bones anyway so I think I'll be alright but I don't want to be on this forever. I've had an "increased appetite" and probably have put on a little bit of weight but nothing noticeable, just be stern with yourself if you get any cravings!! I've upped my excercise to try counter this effect. I'm hoping if I', allowed to take this for a few more months then they'll give me something for the hot flushes - that would be ideal BUT if not it doesn't matter, I've got most of my life back again and I'm enjoying it whilst it lasts. For anyone with Endo/Possible Endo then I recommend giving this a shot, don't rule it out. | F | 23 | 60 days 3.6 1X M | 5/12/2011 | 4 | Prostate Cancer after maximum x-ray | Very depressed, slight weight gain, total impotence and zero libido. Rarely hot flushes. Considerable muscle loss which is not possible to regain thru exercise. Want to be left in hibernation. | Too bad there isn't something to counteract these damned side effects of an otherwise good drug. | M | 78 | 12 months 10.8 mg 1X O | 3/21/2011 | 4 | prostate cancer | most difficult are depression, very poor sleeping weight gain around waist sweating +++ total loss of sex drive | psa 13 prior to starting 7.5 weeks of radiotherapy back in September 2010. which went very well. last psa in Jan was 0.4 last and final injection on the 4th Jan 2011 just hope that the awful side effects will start to lessen | M | 67 | 9 months 10.8mgs 1X O | 3/16/2011 | 4 | gynae probs | now on 4th implant and experiencing problems. started having hot flushes, headaches, diarreahoe,not sleeping. regardless of side effects the pain i experienced is no where as bad as it was. | F | 37 | 4 months 30mg 1X M | 2/10/2011 | 4 | Prostate Cancer - Stage 4 | Hot Flushes, zero libido, some muscle loss | My PSA went from 100 to 6 after first injection. My last PSA was .19. I get the 10.8 every 3 months. During the day I drink cool drinks (O.J., Cider, etc.) or splash my face with cold water for the hot flushes. I talk it over with the ladies. During the sleep hours I kick the covers off until the flush dissipates. As far as muscle loss goes I intend to get off my butt and start some exercise. I'm 75 and so my libido wasn't all that great to start with. Apart from the side effects I mentioned I feel great. Hopefully this will continue. My cancer has metastasized so it would seem that Zoladex is my only treatment. No point in operation, radiation, etc. As I mentioned I'm 75 so compared to many I am a lucky guy. | M | 75 | 9 months 10.8 10X O | 1/3/2011 | 4 | Endometriosis | I didn't find the side effects to be too bad. I did not have hot flashes at all and only had some mild leg tingling for the first two months or so. I was prescribed estrogen add-back therapy which made me nauseous so I only used it twice. Felt much better when I didn't have the estrogen. | I was on a six month course of Zoladex for endometriosis. My last injection was 5 weeks ago. While I was on Zoladex I was still feeling a lot of pain and didn't think it was working. I did have some pain free days but not many. Now that I am off the medication, I wish I was still on it. This last week has been terrible. I am supposed to go in for surgery soon and have adhesions removed again. I am going to ask my doctor if I can go back on Zoladex after my surgery. Not being on it is much harder than I thought it would be. | F | 35 | 6 months 3.6 mg 1X M | 11/13/2010 | 4 | Endometriosis | Very bad headaches nearly all the time, aching all over (similar to the flu)dizziness, forget-fullness | I have been prescribed Zoladex because I have really bad endometriosis plus frozen pelvis (where my left ovary my bowel and my tubes are all adhered to each other by the endo) My Surgeon will not operate on me until the endo had shrunk by the Zoladex. I had the implant in my tummy (which lasts for 3 months) on the 2nd Sept 2010 and I'm booked in for surgery on the 7th Dec 2010. The pain has completely gone since I have taken the Zoladex, I started to bleed a week after the implant which they told me would happen this lasted 2 weeks and nothing since except really really bad headaches and also this really weird aching sensation which is all over but really bad in my legs, my legs feel really heavy and bruised. | F | 33 | 3 months 10.8mg 1X AN | 10/28/2010 | 4 | prostate cancer | Hot flashes. loss of libido, change of charactor(very moody,an absolute asshole).Ive been off of zoladex one year now. seem to be coming out of the mental changes but still no libdo and have hot flashes yet. My midsection and breast are large despite working out 3 times a week and I eat healthy. Went from psa 27 to 0. Don't know if I would do it again. | M | 67 | 2 years 10.8 1X O | 10/27/2010 | 4 | Endometriosis | Hot flushes, mood swings. | Following surgery to remove an endometrioma I was advised to have these injections for 6 months. I have had minimal side effects but best of all no periods. Sexual activity had been restored too! Not sure what is going to happen now. It has been nearly 7 weeks since I had the last one and I'm wanting to get pregnant...If you are having this injection, you can ask for Emla cream to put on beforehand so that it doesn't hurt....ask your doctor. After reading a few websites, I asked my doctor who happily prescribed it. | F | 31 | 6 months 3.6mg 1X M | 10/12/2010 | 4 | Breast cancer | Horrible hot flushes, weight gain | As the side effects are not too bad so far I am happy to continue. Taking it to increase my chances of stopping recurrence of cancer. Have gained 7lbs in the last two months and am worried about how much more I might put on. Hot flushes more bearable in cooler temps so looking forward to Winter. | F | 41 | 7 months 3.6mg 1X M | 10/2/2010 | 4 | Endometriosis | ocasionally sweats, more emotional than usual, pain in joints, vaginal dryiness | I was very scared about taking this, but the symptoms are insignificant. I started to take it after a laparotomy surgery where the doctors find a big endometrioma, and so far no other endometrioma has been found. | F | 27 | 4 months 10.8 X 3M 1X M | 7/24/2010 | 4 | Endometrioma/ Fibroids | Hot flushes, Loss of libido (never had a high sex drive for starters), Pain in shoulders, I am eating so much and always hungry, tingling sensation | This has been a life saver compared with daily pain from endometrioma, severe period cramps and living my life in pain. After my first injection i had my normal period but thankfully on my second injection last month i had no period. I will take my third injection at the end of this week. This is in preparation for IVF as i've had 2 unsuccessful one's. I am hopeful it will end well. | F | 36 | 6 months 36mg 1X M | 7/7/2010 | 4 | adhesions, cysts | hot flushes,night sweats,nausea vaginal dryness and tiredness | My pain has certainly eased off, hoping it will last after I have completed the course, otherwise it is a operation which I would rather avoid. I was two minded at first after reading reviews,but my doctor really thought we should give it a go, but must say everyone reacts differently to all medication and I do not regret it at this point in time. I am also on HRT which seems to help with the side affects. | F | 49 | 5 months 3.6 1X M | 6/29/2010 | 4 | Endometriosis | Fatigue, hot flushes, emotional, spots | I was terrified after reading reviews but it's the best thing I've ever done. I've had 3x monthly injections followed by 1 implant lasting 3 months and the pain of endometriosis has all but vanished. I had a horrendous period 3 weeks after the 1st injection but no problems since. I take Premarin to counteract any side effects and wish I could stay on it forever! The needle isn't as bad as expected - it's nothing compared to the pain of endometriosis but you can have a local anaesthetic. I've had it with and without local and prefer without as it's over and done with in seconds. My last injection should have worn off a couple of weeks ago but no period yet - apparently it can last a month or two longer than expected. I'd recommend trying it! | F | 27 | 6 months 1X O | 6/2/2010 | 4 | residual ovarian tissue | I get the night flushes, Ive had 2 unexplained frozen shoulders, i have swelling of legs due to water retention. My hair has thinned, but I have thick hair anyway, lack of sex drive, nipple discharge | I had numerous operations for ovarian cysts, probably due to endometriosis. The operations caused more harm as i developed adhesions. After an early hysterectomy aged 27 with no children, i thought i could begin my life. How wrong I was. Deep down in the adhesions is ovarian tissue, leftover form the endometriosis. Its unattainable, without major mojor surgery which may damage my bladder, circulation to legs and result in a colostomy bag. So, every month for 11 years I have my injection, with HRT top up. I ve had 4 further cysts in that time, because i was a few days late getting my injection.BUT, and a big but, when you read about our fellow human beings suffering from all theside effects and dealing with cancer, it makes me humble. I am thankful for small mercies | F | 39 | 11 years 3.6 1X M | 4/4/2010 | 4 | Prostate Cancer | Phimosis. Penis contracted to less than half normal. Consultation on 15Jan2010 with regard to full Circumcision. On Zoladex 10.8 for six years. Total Impotence since 2004. PSA 1.7 down from 86 but now increasing. Awaiting latest PSA test result | M | 77 | 6 years | 1/10/2010 | 4 | fibroids | Hot flushes headaches and can't sleep | zoladex has stopped my pain thank god | F | 33 | 3 months | 10/29/2009 | 4 | to reduce fibroids prior to surgery | slight hot flushes, small amount of spotting, tiredness, slightly emotional, slight acne | I had my first of 3 injections 3 weeks ago and apart from the slight side effects listed I have felt fine. I thought it would useful to describe an experience that is not as horrible as others listed here! | F | 36 | 21 days | 10/20/2009 | 4 | severe endometrosis | severe hot flushes, memory loss, fatigue, imsomnia, weight loss, headaches, period like pains, moody etc | i feel so helpless i just want to scream out for help. i feel like someome who suffers from post-natal depression i assume thats how they felt.the injection is horrible i go into a panic attack. Today i got my final of six injection, i will see the doc in the second week of december. i pray everything is well and i can then have my three beautiful children. i will have a panic attack as i enter the room. that needle is so huge and it is painful, my period stops immediately which is the best thing of all with that horrible pain not there anymore except the day before my next injection i will feel some discomfort. thank God this is over for now am just dreading what my period will be like when it does return. | F | 30 | 5 months | 10/20/2009 | 4 | prostate cancer | Hot flushes,some joint pain,loss of libido. 2-year course of injections every 3 months,with radiotherapy reduced psa from 28 to less than 2. | am just about to start further injections to try to reduce psa which has risen to 9 after 2 further years. | M | 72 | | 10/13/2009 | 4 | Breast Cancer | Hot flashes and night sweats resulting in tiredness the next day but overall worth it. Much better than the side effects of tamoxifen, and no painful periods for first time in my life! | Strange as it may seem, I actually found that exercise helped the tiredness - seemed to counteract it somehow, and thus kept weight under control, as well as helping with the flushes as heat was escaping naturally. Am thinking of opting for another course as a possible oestrogen reducer as Tamoxifen is a definite no no for me - terrible abdominal side effects that are quite worrying. | F | 47 | 2 years | 7/15/2009 | 4 | Endometriosis stage II | Hot flushes, memory loss, headaches, nausea, loss of appetite, moodiness, insomnia, no periods | Don't know yet if this drug has helped with my condition, but extremely happy with no menstruation. That on its own has been a relief, I have had a lot of problems with side effects, all of which I can deal with as the benefits outweigh the discomfort. The injection itself looks scary, but not very painful, am happy to have it without a local. I will be relieved when the six months is up, and I'm curious to find out the results of treatment. My doctor also prescribed Livial to counteract the side effects, so I'm guessing that has helped as my problems don't sound as bad as some others on this site. My doctor has been brilliant, so I'd recommend finding one you can really trust. | F | 28 | 5 months | 5/31/2009 | 4 | Failed ablation, endometriosis | Short-term memory loss, mild hot flashes, unexplained tears (onset was 1 week after 3rd injection) | At this point in time, it's better than a hysterectomy. The slight bruising at the injection sites is my only physical reminder. NO JOINT PAIN. Will update my satification, side effects and comments after my 6th injection (4th injection was this morning). | F | 45 | 3 months | 5/26/2009 | 4 | hot flushes,total loss of libido.joint pain,and unpleasant mood swings. | there is insufficient advance information regarding the effect on your emotional swings and the dangers of depression arising | M | 68 | 5 years | 5/16/2009 |