ZOLADEX Reviews (GOSERELIN ACETATE)

Average Rating: 2.9 (291 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION

 Type: Rx Drug

  

ZOLADEX  (GOSERELIN ACETATE):  Goserelin is used in men to treat prostate cancer. It is used in women to treat certain breast cancers or a certain uterus disorder (endometriosis). It is also used in women to thin the lining of the uterus (endometrium) in preparation for a procedure to treat abnormal uterine bleeding. Talk to your doctor about the risks and benefits of treatment. Goserelin is similar to a natural hormone made by the body (luteinizing hormone releasing hormone-LHRH). It works by decreasing testosterone hormones in men and estrogen hormones in women. This effect helps to slow or stop the growth of certain cancer cells and uterine tissue that need these hormones to grow and spread.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15


RATING  REASONSIDE EFFECTS FOR ZOLADEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Prostatic cancer I'm no longer taking this medication. Medication stopped having reference to psychosis/mental health side effects Zoladex appeared to be the trigger for psychosis and after consultations with the oncologist and psychiatrist the medication ceased after 12 months. Unfortunately the mental health illness has not abated with 4 admissions to psychiatric hospital since October 2021, the last in December 2023 M 73 12 months
3.6mg impl 1X day
3/14/2024
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History
 1  Early stage breast cancer This is a horrendous med. I have had severe mood changes since starting. The bone pain is unbearable. Headaches, nausea, kidney pain. Severe depression. Talking about suicide. Memory loss. 40 hot flashes per day. Shortness if breath. I rate this 1. It should be banned. This is like a torture for women. Even when you tell docs how bad it is they don't care. Give you more drugs for depression with more side effects. I'm sure they must get kickbacks from the drug companies. F 53 7 months
30 mg 1X M
8/1/2023
 1  Breast cancer - hormone positive Mood swings, emotional, depression, anxiety, weight gain, muscle aches, extreme irritability I was 34 when dx with BC. Silly me thought it could be a thing of the past. This reminds me daily and adding letrazole makes it even worse. I'm glad I don't have any reoccurrence and I'm grateful but this is horrendous. I hate it. F 37 3 years
3.6 1X M
7/14/2023
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 4  Heavy periods Sweating, hot flushes and headaches. I had fibroids removed but was still having painful periods. Zoladex stopped the periods so I could return to having a normal life. However now doctor saying I should stop as been on it too long. Worried will start having painful periods again. F 43 7 years
3.6 1X M
5/11/2023
 1  Perimenopause, Pmdd and fibroids Would run out before the 28 days and gynae wouldn't give any earlier, used add back but struggled to find a balance due to fluctuations still! Effected my mental health so badly that I've still not recovered despite stopping injection 2 months ago, feel depressed and manic and suicidal on a daily basis Worse thing I have ever had in my body, and m worse than before and won't give me testosterone till after a full hysterectomy and no idea if that's going to solve anything, feel bitterly disappointed that no levels taken, no real support and feel a burden to mental health team, feel worse and like I'm bipolar, it's sent me loopy, Uk based Nhs F 46 5 months
3.9 1X M
3/18/2023
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 3  Endometriosis Acne, mouth ulcers, insomnia, memory loss, decreased cognitive function, depression and diminished libido. Was put on Zoladex and HRT after laparoscopic surgery for stage 4 endometriosis. Using it to down regulate prior to starting IVF treatment. F 27 2 months
3.6mg 1X M
2/19/2023
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 3  prevent Breast cancer reoccurrence extreme fatigue day of and day after shot. mild hot flashes at night. water retention. occasional headaches F 36 2 months
1X M
2/8/2023
 1  Endometriosis Absolutely horrific. Counting down the days until I can stop taking this horrible drug. Hot flushes at any given minute, forgetfulness, joint pain in my arms to the point I can't raise my arms but the worst of all of it has got to be...not sleeping properly and waking up every 1.5-2hrs for long periods of time. Sweating so much at night. As I write this post I've been awake since 4am. From about a week after taking first injection to 3 months later there hasn't been one night I've slept normally. On the plus side I luckily haven't experienced weight gain but instead weight loss. F 34 3 months
X1 1X M
2/3/2023
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 1  Endometriosis Horrific. Heart issues, dizziness, extreme fatigue, heat intolerance, exhaustion, weight loss and then significant weight gain. Zoladex disabled me. I am 10+ years later and have lost everything. My career as an ambulance officer. DO NOT touch this drug! Please! Diagnosed with Papillary Carcinoma a few years later. ZERO health issues prior to Zoladex. I'm living at 30% capacity now, when I used to live at 110%. Please reach out to me if you have had similar experiences. This drug doesn't list the major side effects that it should. F 21 3 months
15 1X M
1/27/2023
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 1  Breast cancer Flashes , swing mood,tiredness F 39 0 days
3.6mg 1X M
11/16/2022
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 4  Breast Cancer reoccurrence Hot flushes very bad, (and I live in Africa) headache, insommia, low libido,moodiness, tummy cramps, mild pelvic pain (it comes and go), constipation, hands stiffness, anxiety attacks, mood swings, more urination, weight gain, and I have abdominal pain. Zoladex plus Arimidex have really saved me from severe breast cancer pains. I have been on this drug for 11 months and I do take my injection every 3 months. I'm very happy now and I do my daily activities without any problems. Thanks to God. I am to be on this drug for 5 yrs. F 41 0 months
1X M
11/11/2022
Email
 4  Prostate cancer that hasn't spread Bad joint pain from head to toe..extreme fatigue..more sleeping...frequent urination....moderate to severe hot flashes mostly at night..mild mood swings....intermittent short term memory loss...same libido but..diminished performance. Not happy with side effects but very happy with significant PSA reduction..on balance I prefer the side effects to the alternative M 64 6 months
10.8 1X O
10/28/2022
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 5  Endometrial lesions Joint pain, hormonal episodes, huge lump/ bruise in injection site. Hot flushes. All of the side effects have been worth it. My debilitating daily pain has ceased... I have my life back, Everyone if different and my side effects may not be as bad as some. Although for me personally zoladex has given me my life back. You have to weigh up pros and cons and do what is right for you and your situation. F 43 9 months
30mg 2X O
6/29/2022
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 5  For endometriosis Bone pain ,headaches, Zoladex helped with pain of endo F 37 3 months
3.6 1X day
4/5/2022
 1  Endometriosis Hot flushes,very bad joint pain can hardly move elbow joints, headache,cried everyday which I'm not like that,hair is thinning and the weight gain is so bad nearly 2st in 3 month. Hot flushes are bad can hardly breathe with them,I've noticed I feel like I'm having a hypo but I'm not diabetic at all I have no idea if it's related but strange I've never had this before ,I have fibromyalgia and the pain since starting this drug is out of this world I can hardly put one foot in front of the other because of the pain and I'm not over reacting .my hair is so thin it's noticeable to others as well.i haven't had period which is the only good thing but I've had every period pain I suffered before but no monthly.I'm crying everyday which isnt like me at all and let's not mention the fact that my sex drive has completely and I mean completely disappeared even to the point that I feel it won't ever come back but for me it's the pain I simply can't cope with it anymore I spend 90% of my life in pain because of fibro but now this is well over 100% pain.gynaecologist never said it would be this bad or I would have never agreed to it.I'm due 3rd implant in 2 wks I WILL NOT be getting it.all I can say is read everything you possibly can about this drug before taking it and ask as many questions to your gynaecologist as you can.sorry for the rant but I'm suffering off this. F 3 days
3X M
1/30/2022
 3  Breast Cancer recurrence prevention Pain in injection area lasting few days. Frequent headaches. Hot flashes mostly at night and wake up full of sweat most nights. Leg pain and soreness. Also seem to have increased urination. So only been on this med for 2 months and due to have 3rd injection in 2 weeks. Taking this along with tamoxifen as was pre menopausal. Was zoladex or chemo according to my oncologist since my oncotype score was on border . Opted for zoladex. So far hasn't been to bad . Have definitely had menopausal side effects with hot flashes being worst of them. Since only been ion med short term can't say if worth it or not yet. Hoping will be worth it as the injections are not fun. I am considering removing my ovaries as well instead of insuring 5 years of this injection! I can deal with side effects for now as long as keeps reoccurrence from happening. I'll take hot flashes over breast cancer recurrence any day. Time will tell I guess and hoping for the best. F 50 2 months
3.6 1X M
9/14/2021
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 4  Endometriosis Hot flashes, vaginal dryness, night sweats, insomnia, changes in mood, headache in the first week after each shot, minor bruising at injection site It took close to 2 months before I stopped having endo pain and related bowel problems, and most of the side effects didn't start until around then. I had a *very* heavy period about 3 weeks in (which was my first in 2 years, due to having been on 10mg Aygestin), and then some spotting around 3 weeks later (which would be my usual cycle), but after that there was no more. I have a history of blood clot, so I can't take estrogen add-back to help with the side effects. I took Estroven Complete (the rhubarb one, which has no soy) and that did seem to help some with the hot flashes and insomnia. Overall, the side effects were unpleasant, but well worth not having the pain I was in all the time. My pain was nearly every day, but was totally debilitating during a few days per cycle... for the past six months I haven't had to plan my entire life around when I wouldn't be able to get out of bed. I hope my upcoming excision surgery will make that a permanent thing, but if the endo comes back before menopause I wouldn't hesitate to have another course of Zoladex. F 40 6 months
3.6mg 1X M
7/15/2021
Email
 1  Thin endo lining after myomectomy Weight gain, mood swings, hot flashes and night sweats, stopped periods. 2 years later and my periods haven't actually returned, still have hot flashes and fibroids and adenomyosis have grown back F 39 3 months
30Mg 1X M
6/22/2021
Email
 2  Avoid breastcancer recurrence Muscle pain in chest and one arm. Arm feels stiff. Stomach bloating. Sweating. Depression. Mood swings. After last finnishing dose, 3 months ago still sweating and mood swings/depression. Waits for periods to returns and see if that Will help. Hormones seem very unbalanced. Seem to affect you quite long after you stop the injections. F 41 9 months
8X day
6/3/2021
Email
 2  Fibroid on my cervix Extremely tired, aching joints, nausea, very irritable, insomnia, hot flushes, headaches. Generally feel like crap. I'm on this in hope it will shrink my 10 cm fibroid on my cervix that also prolapses several times a day. Mostly when I go to the bathroom. I was told max 6 months then op to remove. My normal consultant was away yesterday when I went for check up and injections done. New guy said it will be 12 months and full hysterectomy. Where as previous one said it would be 6 months then remove fibroid. I can't do this for 12 months I'm in pain and exhausted it's effecting my work. I just want it gone F 42 4 months
3.2mg 1X M
4/16/2021
Email
  

ZOLADEX  (GOSERELIN ACETATE):  Goserelin is used in men to treat prostate cancer. It is used in women to treat certain breast cancers or a certain uterus disorder (endometriosis). It is also used in women to thin the lining of the uterus (endometrium) in preparation for a procedure to treat abnormal uterine bleeding. Talk to your doctor about the risks and benefits of treatment. Goserelin is similar to a natural hormone made by the body (luteinizing hormone releasing hormone-LHRH). It works by decreasing testosterone hormones in men and estrogen hormones in women. This effect helps to slow or stop the growth of certain cancer cells and uterine tissue that need these hormones to grow and spread.   FDA Approval Date: 1989-12-29 (Sources: U.S. Centers for Medicare Services, FDA)

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