Drug Ratings for ZOLADEXAverage Rating: 3.1 (167 Ratings)
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Results are sorted by Date Rating Was Added Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 |
| RATING | REASON | SIDE EFFECTS FOR ZOLADEX | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 1 | IVF | I have had severe headache on both sides of my head.I regret taking this injection! | F | 40 | 1 months 3.6mg | 4/29/2013 | 4 | Treatment of Fibroids pre Surgery | I have been on Zoladex injections for 3 months for the treatment of Fibroids pre surgery. I was supposed to have one more but i have been told by the Doctor that it isnt required as the Operation date is now set! After reading some peoples experiences i just wanted to add my own as i found other peoples reviews helpful. My side-effects arent that bad so far, most of them are a mild inconvenience. I found that the weight gain can be controlled if you exercise regulary and dont over induge, especially if you are feeling low or emotional. Exercise aslo made me feel alot better and helped me when i couldnt sleep. Im a person that loves my glass of wine and my daily coffee, so i didnt cut out alcohol nor coffee, but my side effects arent that bad still indulging on these guilty pleasures. Im not sure if the medicine has worked yet as im due for surgery in 3 weeks time. I do feel that the pressure on my bladder from the fibroid has reduced as i dont feel the need to go to the loo that often now. And no more heavy, painfull cramping periods, so in that respect it is working!. Hope this helps anyone who has fibroids or is taking the Zoladex 28 day injections!, will update the post once ive had surgery! | F | 32 | 90 days 3.6mg 1X M | 4/16/2013 History | 3 | Endometriosis | Headache, nausea, vomiting, feeling unwell, dizziness, upset stomach | Had Laparoscopy in Nov 2012 and some endo removed, mirena fitted, but had bad side effects from mirena. Gyno suggested zoladex as still in pain. 1st injection increased pain for about 2 weeks, some side effects but not to bad, week 3-4 pain most days but nothing i couldn't cope with. had 2nd injection 1 week ago OMG. side effects within 2 hours of injection, severe pain, the next day more pain, vomiting, bad head to the point where i had to go to bed, spent the next two days mostly in bed ( not great when you have kids) still got bad head, dizziness, cheeks tingling and warm, nausea and my stomach is also upset.NO WEIGHT GAIN, as i eat very healthy and exercise loads when I'm up to it. When I train I am pain free, due to your body releasing endorphins, that combined with meditation keep my mind and body strong. | F | 35 | 6 months 3.6mg 1X M | 3/19/2013 | 1 | Menorrhagia/pre-uterine ablation | Emotional liability, severe bleeding, memory issues, fatigue, hot flushes | This drug did not work, in fact, it had the opposite of the intended effect. My blood loss has gotten so bad that I've gotten badly anemic and my period just no longer stops. I have to be in progesterone 3 times a day just to slow it down. | F | 43 | 1 times 10 1X O | 3/17/2013 | 3 | currently taking for endemetriosis | I have had it fitted 4 1 week currently experiencing suicidal thoughts depression hot flushes nausea tiredness and dizzyness doc says it shouldn't work just yet but it obviously is and I am worried that it says only 2 take for 6months max yet I'm on it for 9months!? | F | 20 | 9 months 30mg | 2/14/2013 | 5 | Endo | Initial mood swings, emotional , hot flushes, night sweats, some nauseous headaches | F | 47 | 6 months 3.6 | 2/7/2013 | 3 | Fibroids to reduce size | Hot flashes about every 30-40 minutes mostly in evening . Night sweats. Inability to sleep due to being boiled or freezing. Severe blinding headache on waking . Dry skin . Very tired. Foggy brain. Feeling fed up. | F | 47 | 3 months | 1/16/2013 | 4 | Prostate Cancer | Worst side effect is erectile dysfunction, shrunken testicles and penis. Next comes fatigue and general tiredness. Next is loss of memory and lack of mental energy. Restless sleep and hot flashes, muscle weakness, paticularly in legs, 16 pounds weight gain. Inceased appetite for food. These are the main effects. Otherwise I am happy and glad to be alive. | 10.8mg every 3 months. | M | 64 | 2 days 10.8mg 1X O | 1/15/2013 | 4 | Intravascular leiomyomatosis | Taken with Letrozole massive tumour shrinkage (myomas/fibroid in vascular system). Chronic insomnia, problems with immediate short-term memory, zero libido, severe hot flushes, joint pain & stiffness, muscle spasm in hands/fingers, lethargy & low mood. DHEA, calcium / magnesium, vit D, fish oil DHA helped. Avoid wheat and beer, alcohol generally will make symptoms worse. Now stopped taking and trying ulipristal acetate (specific to fibroids only) plus calcium-d-glucarate, DIM, matcha green tea & phytoestrogens: red clover, black cohosh ie SERMS & SPRMs, to flush out excess estrogen & progesterone. Be careful before stopping Zoladex. It works. Get your disease stabilised before trying alternatives and always involve your clinicians, even if they don't agree with your choices they can offer blood tests & imaging to check disease remission or progression as you try something else. Btw, one month off Zoladex side effects remain even though it can take as little as 14 days to flush from system, my guess is that it can take much longer! | F | 40 | 2 years 3.6mg | 1/4/2013 | 2 | Endromerriosis | Really bad mood swings, irritable & depressed. | F | 29 | 6 months | 12/28/2012 | 1 | Severe Endometriosis | Suicidal thoughts and depression. Constant hot flashes and huge weight loss. | F | 23 | 6 months N/a | 11/26/2012 | 2 | nauses headaches daily | I have had the injection once and will not be getting it again it has made my pain 10 times worse | F | 22 | 1 months 1 | 11/23/2012 | 4 | Endometriosis | Hot flushes, night sweats, tiredness, bowel issues, mood swings. | As someone who rarely sweats, the night sweats and hot flushes were the hardest part of this treatment. The last 6 months being endo pain free has been amazing to have a "normal" life - whether this treatment has helped long term, only time will tell! | F | 26 | 6 months 1X M | 11/6/2012 | 4 | endometriosus/cysts on ovaries | After 17 years of endo pain.10 surgeries a radical hysterectomy leaving the ovaries behind.I had surgery last november and two weeks after I had a cyst that bleeds into itself every cycle.I was having pain ALL the time and it was interfering with work my social life.Upon last admission with regular morphine every hour over two days Zoladex was suggested to which I had on discharge.I have now been on Zoladex for three months and due to start my first quarterly injection.I have to date had NO pain.However my side affects are brutal.Depression nausia sleeplessness hot flashes and terrible debilatating bone aches especially between my hips and knees.It's so severe at times I have to take DHC to combat it.I will admit that this is NOTHING compared to the pain I dealt with daily and the severe cycle pain with the cysts so I can say that although the side affects are strong it's liveable. | F | 33 | 3 months 3.6 mgs 1X M | 11/6/2012 | 3 | endometriosis (after Laparoscopy) | Tiredness, hot flushes, disrupted sleep, slight moodswings | F | 29 | 6 months | 11/2/2012 | 4 | Endometriosis | hair loss, a heavy hair loss!!! acne, mood swings, hot flushes, bone pain, osteoporosis. | F | 25 | 6 months | 10/31/2012 | 1 | Breast cancer when young.. | Hot flushes pain in stomach from implant..constant sick feeling itching..pins n needles..being sick..and it didnt stop periods like it was meant.. | F | 43 | 2 years 25 | 10/19/2012 | 3 | Uterine Fibroids | Hot flushes but diminishing, restless legs, dizzy spells, pins and needles and numbness in hands (not known if this is result of injections), generally tired | Have now had five injections - one more to go. Have large fibroids (eight month pregnant uterus). Even though side effects have been difficult it has been better than constant flooding (ended up in hospital twice) and pain as I had not reached menopause (at 57). Hoping menopause will kick in after finishing treatment otherwise it will mean a sub-total hysterectomy. Fibroids appear to be shrinking a little but not a great deal and bleeding stopped. | F | 57 | 5 months 3.6 mg 1X D | 10/16/2012 History | 5 | Prostate cancer | No libido,hazy thinking,lack of concentration,hot flushes,mood swings. | The last two injections have been really painful.I seem to have become sensitive to the rather large needle.Bruising at the site (tummy) and quite sore for a few days.No problems previously.Same doctor same everything else.Will have a local in future. | M | 64 | 2 years 3.6 1X M | 10/9/2012 | 3 | awaiting hysterectomy | Just had my 2nd injection yesterday, feel awful, disturbed sleep, night sweats, cannot concentrates, very emotional. Roll on the next one !!!!! | F | 38 | 1 days | 9/24/2012 | 3 | Endometriosis | Hot flushes, night sweats, increased pulse rate, lower back pain, lethargy, insomnia. | Although I've been bleeding for 2 weeks (not heavily), I haven't had the usual agony associated with Endo, so am willing to cope with the side effects if it works!! | F | 34 | 5 weeks 1X O | 9/4/2012 | 2 | Endometriosis post-op cystectomy | Migraines daily, insomnia, loss of apitite, vomiting, crying,angry,depression, sweating, bad hot flushes all in month 1 i'm dreading the next 5 :( | I'm receiving this zoladex treatment after I had a 9cm chocolate cyst removed from my left ovary through laparotomy I'm hoping this suppresses the disease I never want to experience that pain again! | F | 21 | 6 months 3.6mg 1X M | 7/24/2012 | 3 | Prostate Cancer stage 3 | Was diagnosed with Prostate Cancer stage 3, and prescribed with hormone treatment to be followed by Radiation therapy, either Brachy or beam therapy. Reading other peoples side effects just wanted to say I am feeling lucky | So far side effects are general tiredness, and not sure if my aching joints are Zoladex related as I also have polymyalgi Rheumatica and RA being treated with methotrexate. Before starting Zoladex treatment my wife checked potential side effects and changed my diet as follows; Now eat only Soya bread (in UK we get Burgen's Soya & Linseed Loaf), to date no hot flushes, and minimal mood swings, my wife swears by Soya for all menapausal symptoms, she used Alpro Soya milk in cereal occasionally. worth trying if it eases discomfort of hot flushes. | M | 72 | 3 weeks 10.8 1X O | 7/23/2012 | 2 | Endometriosis | Hot flushes, insomnia, mood swings, highly emotional, loss of libido, nausea, headaches, flu like symptoms. | F | 20 | 4 months | 7/22/2012 | 1 | Prostate cancer | Jaw twitch, headache, waves of nausea whole day, irregular heartbeat, difficulty breathing, can't sleep, general weakness, loss of memory, muddled thinking anxious, super sensitive skin, hurts to touch things, quality-of-life here is near zero, taking this will make you wish that you were better off dead, advice, don't take this stuff | Take this drug off the market | M | 71 | 3 days Injection 1X AN | 7/16/2012 | 4 | Endo/Adenomyosis | Extreme endo pain, bleeding and moods in first month. Then felt really well, no pain, no bleeding. Now at 5th injection have hot flushes, night sweats, painful bones in feet, extreme tiredness and nausea/flu like symptoms. Am starting counselling too as had to come off HRT due to it feeding endo, and feel very down, crying, etc. | I will be on this until a hopeful total hysterectomy with oavary removal. | F | 37 | 5 months 3.6mg 1X M | 6/24/2012 | 4 | Prostate Cancer | Weight gain, headaches, flashes, zero libido, joint pain, lack of stamina, some mood swings but overall not that bad. Took an injection every 3 months | Prior to being diagnosed I had started my journey towards becoming a vegan. When I gave up all dairy, I dropped 24 lbs in 4 weeks. My oncologist was concerned that I was still losing weight while on another drug Luprilyde (I think). Well, I don't eat meat, chicken or any dairy but ballooned back all the weight. After reading this site, I finally understand my 2 year old headache. The joint aches and pains; muscle mass loss, flashes and zero libido are all right up there with my other fellow PC buddies. My PSA was 15.5 and Gleason score was at 10. According to all the tests, my PC had not yet metastasized. My treatment was HDR Brachy Therapy followed by 5 weeks of daily LDR radiation. My PSA has been at <0.01 for over a year and I just had my last injection. We don't know what's in store for me but time will tell. Hopefully, I'll have a lot of "time to tell". To say that this drug saved my life would be an understatement. I wish I had seen more of the side effects sooner but I guess doctors will tell you the bare minimum to curtail any psychosomatic symptoms through the power of suggestion. | M | 60 | 2 years 30 MG 1X O | 6/13/2012 | 3 | endometriosis | Hot flushes, migraines, nausea, mood swings, sore joints. | F | 28 | 6 months 3? | 5/12/2012 | 3 | endometriosis | Nausea,moody,dizziness,terrible headache,flushes,sweating a lot | F | 28 | 9 months 80mg | 5/10/2012 | 3 | Endometriosis | Migrains , sick feeling in my stomach causing loss of appetite, disgusting skin very dry and acne, joint pain, spotting, cramps ! Very moody, cry over the stupidest things that usually I wouldn't even blink at, depressed feeling started kicking in after the 3rd dose. I've already had operations to remove it but that was less then a year ago and it's already worse then the start. I guess it's helping with no periods but definently thrown in the deep end hoping for the best results possible so this was worth it | F | 21 | 4 months | 5/7/2012 | 3 | severe endometriosis, pre surgery | On the 4th day after implant each month suddenly felt dreadful with chills, severe nausea and loss of appetite lasting 48hrs with some abdominal and back pain. First week severe headaches, following weeks mild occasional headaches. Hot flushes. Waking up throughout night feeling hot. Dry lips, skin and hair. UTI. Joint aches, mostly in shoulders. Apathy and depression. Zero libido. | Painless but heavy bleeding for 1 week after zoladex was implanted. On positive note no period, no endo pain. Will find out how successful zoladex treatment was when I have laparoscopy after three months of supression. Doubt I would agree to use this medication again due to side effects. | F | 31 | 2 months 1X M | 5/2/2012 | 4 | PROSTATE CANCER | The Zoladex as a medication works fine; I've had it over 17 years whenever my PSA exceeds 4 along with Casodex (Prevents flare) 6 times; 5 times I sat in a chair and the RN grabed abdominal flesh and shot the slow 12 week release Zoladex under my skin. THIS LAST TIME THE RN ORDERED ME TO LIE FLAT ON MY BACK IN A BED TELLING ME IT WOULD BE EASIER FOR HER TO ADMINISTER AND SHE SHOT IT INTO MY ABDOMINAL CAVITY AND LACERATED A MAJOR ARTERY CAUSING MASSIVE HEMORRHAGING WHICH I ESTIMATE ABOUT 4 PINTS OF BLOOD INTO MY ABDOMINAL CAVITY; THEY DIDN'T SIPHON AND TOLD ME IT WAS BEST TO BE NATURALLY ABSORBED AND THIS IS CAUSING ME LONG LASTING PROBLEMS. HOSPITAL IS IN DENIAL FIRST TELLING ME IS WAS A MEDICATION REACTION AND THEN TELLING ME IT WAS THE FAULT OF THE SYRINGE. ASTRA ZENECA SAID THEY WOULD INVESTIGATE AND NOTIFY THE FDA AND DIDN'T SO I FILED REPORT WITH FDA AND WILL HAVE LEGAL ACTION AGAINST ALL PARTIES. | I noted in FDA files someone in 1999 had colon and intestines lacerated when Zoladex was injected. Has anyone else had laceration when Zoladex administered, if so do contact me! | M | 79 | 1X D | 4/20/2012 | 4 | Endometriosis & Adenomyosis | F | 30 | 3.6mg 1X M | 4/6/2012 History | 4 | Endometriosis | Terrible headache after first injection, lasted 2 weeks. Then slight headache in the 24hrs after each injection. Dry mouth, dry skin, complete lack of libido, painful intercourse, lost weight (am slight anyway so this wasn't good), hot flushes after month 2, terrible mood swings after 3rd month - completely emotional and unreasonable. Month 5 now developing bone pain and exhaustion. | No periods, no bleeding, no bloating, no endo pain. Felt generally very well until month 3 when side effects kicked in.However my endo pain is non-existent and I am grateful for that. One more injection to go... | F | 40 | 5 months 3.6mg impl 1X M | 3/2/2012 | 1 | Gyne proba | Hot flushes, extreme confusion, tearfully, depressed, mood swings, abdo pains, foggy head and could barely string a sentence together. | F | 35 | 2 months 3.6 mg | 2/29/2012 | 4 | Breast cancer, oestrogen positive | Hot flushes , low sex libido , joint pain , mood swings ! | I get this injection every 28 days and take femara (used to be tamoxifen first 4 years) every day . It is hard sometimes but the alternative is harder . I want to live ! | F | 44 | 10 years 3.6mg 1X M | 2/17/2012 | 5 | Breast Cancer | Weight Gain and Hot Flushes | Was on Tamoxifen and Zoladex - but hopeless with a pill a day, so only on Zoladex monthly injections now. Doing my injection myself each month is a nice reminder that I AM a survivor and that I'm grateful for this medicine to put me in a better position further on down the track. Zoladex for me is easy - no fuss. And I'm so grateful I don't have periods anymore!! Just gotta remember to get out there and exercise more to combat the weight gain. | F | 41 | 18 months 3.6mg 1X M | 2/15/2012 | 3 | elevated PSA | Following radiation and protstatectomy put on Zoladex. Hot flashes (20 per day),total loss of libido and personality changes (not for the better) and joint pain ensued. Vowed I would rather die than do it again, but when presented with that alternative last week when PSA rose to 5.8 have reluctantly decided to resume Zoladex injections. | Like so many others have commented, while the PSA will go down and the metastased cancer areas will no doubt stop growing, perhaps even shrink, the side effects for some are very disturbing. Having been off Zoladex for 5 years and vowing never to go on it again, there are no other options if you wish to keep living. Perhaps the antidepressents I have been prescribed will help the dreaded side effects. As a male I certainly sympathize will all the ladies suffering from menopause and the hot flash syndrome. 20 of those attacks a day and living in perspiration at night along with the mood swings are no treat. An alternative to this drug without so many side effects would be most welcome. For any man reading this post, if you need the drug and suffer afterward you are not alone, hang in and hopefully after a few injections (I had 3) you can go off for a few years before facing the ordeal again. I must mention that I have an older (80 yr) male friend who has taken Zoladex with relatively few side effects so there is hope your personal experience will be better. | M | 69 | 9 months 10.8 1X O | 2/12/2012 | 5 | Endo & Chocolate Cysts | Migraines, Hot Flushes, Night Sweats & Joint Ache in the latter months of taking it. | F | 37 | 10 months 1xM | 1/21/2012 | 3 | endometriosis | feel,weak, nauseated, vomiting, and tired constanly. hot flashes and joint pain.It has only been one month 5 more to go. | hope to see improvement. | F | 30 | 6 months ??? 1X M | 11/22/2011 | 3 | pre TCRE | emotional and irritable after 1st dose, with one day of whole body pain.....after 2nd...unbearable bone pain,vomiting, vaginal dryness/soreness,permanent headache, wheezing and generally feeling like im going to die. | Thankfully i dont have to have another of these nasty implants, but if the surgery following this drug is successful i would say that however horrendous it has been, it will be a small price to pay to get my life back. :) | F | 40 | 2 months 3.6mg 1X M | 10/30/2011 | 4 | Recovering from Endometriosis | Night sweats / hot flushes, constipation, headaches, fatigue, moodiness | Had a cyst removed from my ovary & severe endo removed. Post-surgery - Im well into month 2 of Zoladex. Initially I had nausea but this could have been the onset of my first period which arrived a week after my first shot! Pain was still there but far less than pre-surgery. Night sweats started 2 weeks after 1st shot & now into 2nd shot Im having hot flushes during the day too. Headaches regularly & constipation plague me too. Looking forward to my last shot in 4 months!! | F | 33 | 6 months 3.6mg 1X M | 10/22/2011 | 5 | Endometriosis | Headaches (only the first week or so), hot flushes, night sweats, slight forgetfulness | So far so good! Having hot flushes and night sweats is much better than being in pain - though I had the Zoladex LA 10.8mg injection right after my laparoscopy to remove chocolate cysts on my ovaries, so maybe the surgery helped with the pain too. | F | 32 | 3 months 10.8mg 1X O | 8/12/2011 | 2 | Possible endometriosis | Insomnia, nausea, memory loss, hot flushes | I was asked to try Zoladx injections by the gynaecologist as he suspects I have endo. I have all the symptoms however only have small adhesions on the ligaments at the bottom of the uterus. There is no other sign of the endo. I tried tri-cycling the contraceptive pill which worked for a few months as I didn't experience pain mid-cycle but then the usual pains and swelling returned and the last period was that bad that I was about to ask for a hysterectomy! I had 1 x Zoladex injection and although there was no endo pain the side effects were horrendous. I am seeing the gynaecologist privately and he had written to my GP to ask that they perform the remaining injections. GP told me that they would use Prostap instead of Zoladex and the 2nd injection was therefore Prostap. Since then I have experienced no pain whatsoever, the insomnia and nausea have disappeared and I only occasionally have a hot flush. I saw the gynaecologist a couple of weeks after the 3rd injection (so 2nd Prostap) and he is really pleased that I am not experiencing pain and has suggested I continue for up to 18 months. I will now start to take some form of add back therapy to stop me fully going into the menopause. I am also going to take calcium vitamins. All in all I am happy on the Prostap but suffered on the Zoladex. | F | 33 | 1 months 3.6mg 1X M | 7/22/2011 | 3 | Adenomyosis | Terrible Headaches, Whizzing fuzzy head. Hot flushes. Extreme fatigue. Weight gain. dizzyness. Very emotional and tired during week 4 of each injection. Dry skin too. | Have possible Adenomyosis which is difficult to diagnose. Prescribed 3 months zoladex to confirm diagnosis before hysterectomy. Adenomyosis symptoms disappeared by week 2 so Zoladex did work well. However side effects so bad Doctor didn't do 3rd injection as Zoladex had already shown what he needed & I couldn't bear it anymore. | F | 40 | 2 months 1X M | 7/17/2011 | 3 | endometrosis | Memory loss confusion horrendous hot flushes and night sweats swollen feet and ankles joint pain numb toes and feet.Weight gain changes in hair | I had a hysterectomy 14 years and my endometrosis has returned and i have cysts on my ovary i would not take zoladex again due to hot flushes and night sweats i have not had more than 30 minutes sleep at one time for 4 months. I have hot flushes every 30 minutes this is affecting my work and family life .I have aching joints swollen ankles and feet nunb toes i can hardly get down the stair in the morning due to joint pain in my feet and ankles. What have i done to myself i have now to go for a bone scan due to bone thinning caused by zoladex i wish i had pushed to have my ovaries removed. Cant wait to stop Zoladex and get my life back | F | 47 | 5 months 3mg 1X M | 6/19/2011 | 3 | Stage 2/3 Endometriosis | Hot flashes, more emotional/irritable | Ever since I was 12, I have been having horrible periods. After being on Depo Provera for a year, I started bleeding for two months straight and I became severely anemic. I was put on birth control pills along with Depo then taken off Depo and put on a pill with a higher dosage. Long story short, I finally saw an OB-GYN and the next day I got surgery to diagnose Endometriosis. I am 4 shots into the 6 shot Zoladex treatment. The only time I bled was when I first started on Zoladex due to estrogen withdrawal. I haven't noticed a change in my endo symptoms because I'm not bleeding (I didn't bleed on high dose BC pills either). After the 6 months are over, I am going to go back on Depo. If severe cramps and heavy bleeding return, I will have another surgery to burn off the lesions. I have hot flashes all day long and very bad ones at night as well. I am from the heat and have sweat more in the last 3 months than I have my whole life. I am a lot more emotional and at times when I get frustrated I just want to cry and punch something. | F | 19 | 3 months 3.6mg 1X M | 5/19/2011 | 4 | Possible Endometriosis | Side effects: Hot flushes (daily and nightly) Occasional headache (never used to have them before) Brain "fog" Interrupted sleep (sometimes due to night sweats) Feeling over emotional | Doctor is trialling me on Zoladex to try get a diagnosis as to whether it is Endo or not. It's been the best 3 months of my life for years. No periods at all - it's been the best break ever! I used to get severe painful periods that lasted 3-4 weeks in full swing which meant I was off work most of the time. I've had a full 3 months in work and it's been fantastic to be back properly. Yes the hot flushes are awful and some of the other side effects but compared to what I was experiencing before it is absolutely worth it - hands down. I can't rate it as a 5 as I'm not "cured" yet, going back in a couple of weeks to see if I'm going to stay on Zoladex for a few more months (fingers crossed) and what they'll do next. Am a bit worried about the whole "bone density" thing but I've got freakishly strong bones anyway so I think I'll be alright but I don't want to be on this forever. I've had an "increased appetite" and probably have put on a little bit of weight but nothing noticeable, just be stern with yourself if you get any cravings!! I've upped my excercise to try counter this effect. I'm hoping if I', allowed to take this for a few more months then they'll give me something for the hot flushes - that would be ideal BUT if not it doesn't matter, I've got most of my life back again and I'm enjoying it whilst it lasts. For anyone with Endo/Possible Endo then I recommend giving this a shot, don't rule it out. | F | 23 | 60 days 3.6 1X M | 5/12/2011 | 3 | Gyno problems | hot flushes, headaches, migraines, full body sweats, back aches, UTI, blocked batholin glands, mid to sever depression | I had it for gyno pains, got 1 period after injection that lasted for 18 days very heavy, flushes and sweats very extreme, mild depression, turn into sever depression, constant headaches turning in migraines by the end of day, 2nd and 3rd month no period yay!!. Didnt stop infections associated with my 1st period. But on the up pain improvement was remarkable, I was in sever pain for over 6 months and within 2.5 weeks pain improved by 80% and now by 95% I would recommend for the pain but as for other side effects will never take zoladex again, i went from being bed ridden with pain, to being bed ridden with sever depression, really not worth it when you work full time and have 4 children to raise on your own. | F | 35 | 90 days 10.8mg 1X O | 5/2/2011 | 3 | Pre-fibroid removal operation | Insomnia, acne, some forgetfulness, mild night sweats | i wouldn't have taken this drug if it wasn't a necessary pre-requisite for the operation. I was hoping that at least the benefit would be mild or no period to counter balance the side effects but no... I had a full on heavy period as usual 2 days later than normally expected and it dragged on for two and a half weeks but the last week or so was spotting which I seem to have intermittently now since my second injection. The sweats aren't so bad but contribute to the insomnia. I suspect that as a result of a lack of sleep I have caught a cold. | F | 43 | 7 weeks lowest dos 6X W | 5/1/2011 | 2 | Fibroids | Hot flashes, migraines, short term memory loss, moodiness, irritability | I took Zoladex for 4 months in an attempt to shrink very large fibroids. Largest of 4 fibroids was 10 cm; my entire uterus was involved, some of the fibroids were calcified. My gynecologist was optimistic about shrinking them enough to do a vaginal hysterectomy. Initially, the fibroids seem to shrink a little, however, by the 3rd shot, they started to grow at a rapid rate. A little after the 4th shot, I had a total abdominal hysterectomy; the fibroids had grown significantly larger. Even though the result was disappointing for me, I'm glad that we tried this course of treatment. | F | 46 | 4 months 3.6mg 1X M | 4/18/2011 | 3 | Fibroids | Breast tenderness and increase in size, no concentration, tingling in hands and legs, muzzy thinking, weird rush like feelings in my head, itchy scalp. | I have to do one thing at a time, not my usual self and a bit crabby. But if it can stop the bleeding and reduce the fibroids it will take pressure of other areas - Increasing exercise does help release the tension, swimming is good. | F | 47 | 14 days 1X M | 4/1/2011 | 4 | Prostate Cancer after maximum x-ray | Very depressed, slight weight gain, total impotence and zero libido. Rarely hot flushes. Considerable muscle loss which is not possible to regain thru exercise. Want to be left in hibernation. | Too bad there isn't something to counteract these damned side effects of an otherwise good drug. | M | 78 | 12 months 10.8 mg 1X O | 3/21/2011 | 4 | prostate cancer | most difficult are depression, very poor sleeping weight gain around waist sweating +++ total loss of sex drive | psa 13 prior to starting 7.5 weeks of radiotherapy back in September 2010. which went very well. last psa in Jan was 0.4 last and final injection on the 4th Jan 2011 just hope that the awful side effects will start to lessen | M | 67 | 9 months 10.8mgs 1X O | 3/16/2011 | 3 | fibroids to shrink | mood swings,headache,sickness,hot flushes,forgetful,tired | Nurse told me only side effects was hot flushes! Didn't believe her. | F | 43 | 3 months 3.5 1X M | 2/14/2011 | 4 | gynae probs | now on 4th implant and experiencing problems. started having hot flushes, headaches, diarreahoe,not sleeping. regardless of side effects the pain i experienced is no where as bad as it was. | F | 37 | 4 months 30mg 1X M | 2/10/2011 | 3 | Shrink Fibroids before operaton | 3 to 4 years ago i was put on Prostap had 3 injections to help shrink fibroids..due to very high blood pressure op had to be cancel twice. Moved years later..fibroids bigger and causing problems..i have now to start 2 doses of Zoladex one taken this month and the last to be given next month prior to op in March..so far i have been emotional for no reason, spots, aching and very tired..can't switch off from everything..irritable. Fingers crossed will have my operation 3rd time lucky i hope! | F | 40 | 1 months 1X M | 1/30/2011 | 4 | Prostate Cancer - Stage 4 | Hot Flushes, zero libido, some muscle loss | My PSA went from 100 to 6 after first injection. My last PSA was .19. I get the 10.8 every 3 months. During the day I drink cool drinks (O.J., Cider, etc.) or splash my face with cold water for the hot flushes. I talk it over with the ladies. During the sleep hours I kick the covers off until the flush dissipates. As far as muscle loss goes I intend to get off my butt and start some exercise. I'm 75 and so my libido wasn't all that great to start with. Apart from the side effects I mentioned I feel great. Hopefully this will continue. My cancer has metastasized so it would seem that Zoladex is my only treatment. No point in operation, radiation, etc. As I mentioned I'm 75 so compared to many I am a lucky guy. | M | 75 | 9 months 10.8 10X O | 1/3/2011 | 3 | Stage IV Breast Cancer | Severe headaches; weight gain (10 lbs.+); blurred vision/eye twitching; Hot flashes. | Taking Zoladex with Tamoxifen to curb estrogen production(premenopausal); Also on Herceptin; I tried Zoladex injections for 11 months and finally threw in the towel;there were days I could not function after the injection because of the headaches and eye twitching/vision issues. Did not experience weight gain right away - just over the last few months. I have been in remission for over a year and am generally in good health. I did not feel bad after every injection and the worst side effects may have occurred when the injection coincided with my Herceptin infusion. Zoladex did work - it kept me in menopause -hot flashes and all. Opted for surgical removal of the ovaries. | F | 49 | 11 months 1 1X M | 11/30/2010 | 2 | endo | my experience with zoladex have been good and bad. after my first implan i hardly had any bleeding and pain which was fantastic. ive bled sooo heavy and lost lots of large clots and am always aneamic so having the bleeding and pain stopped was just fantastic. then it all went downhill from my 2nd implant. the headaches are unbearable, hot sweats, extreme anxiety, mood swing, crying, nervousness, lack of concentration, memory loss, chronic joint pain and then yesterday i collapsed at home and my husband rang an ambulance. my blood pressure was 230/130, which the paramedic said was life threatening. i also had a temperature. the a and e doctor said it was down to the zoladex. im supposed to have my 3rd implant this friday and my family dont want me to have it done. its a catch 22 situation, if i dont have it then the pain and bleeding will start but if i do have it then im so scared of the side effects as its got worse with each one. my only hope for getting my life back is for my specia | F | 38 | 2 months 1X M | 11/16/2010 |