MAXZIDE Reviews (HYDROCHLOROTHIAZIDE; TRIAMTERENE)

Average Rating: 2.8 (42 Ratings)

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 DIURETICS

 Type: Rx Drug

  

MAXZIDE  (HYDROCHLOROTHIAZIDE; TRIAMTERENE):  This drug is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is a combination of two "water pills" (diuretics): triamterene and hydrochlorothiazide. This combination is used by people who have developed or are at risk for having low potassium levels on hydrochlorothiazide. It causes you to make more urine, which helps your body get rid of extra salt and water. This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.   FDA Approval Date: 1988-05-13 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MAXZIDECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Peripheral edema Developed squamous cell carcinoma on my leg. Recent derm studies show an increase for this skin cancer in people taking thiazide diuretics. The drug worked but I stopped because of this. I am waiting out up to 4 weeks to see if the fluid balance normalizes (can have rebound edema from stopping after long term use) before my doctor would prescribe an alternative. After two weeks I am seeing less edema. Yes I gained a few pounds but am restricting sodium more than I was. Was great at first until my derm biopsied a lesion that is SSC. F 63 20 years
25 mg 1X day
7/9/2018
 1  High Blood pressure Severe constipation with stomach pain, bloating, tired, foggy, not tracking well, muscle aches, vision blurry, out of breath when walking short distances, a miserable experience. I’m getting off tomorrow now that I’ve done research and learned about it. Don’t take. Long and short term affects. I mean any drug that depletes sodium, water and potassium can’t be a good thing. Look up what happens to your body without those chemicals. F 56 1 years
75-50
5/17/2018
Email
 1  High bp After just 4 days on maxzide, my potassium was depleted causing me to lose consciousness. My heart beat was under 50 bpm. Had I not been rushed to the ER I would have died. This medication is dangerous. F 65 4 days
?
3/24/2016
 1  Hypertension This is a horrible medication due to side effects. I had severe cramps all over the body, especially the legs, stomach and back. Couldn't take the cramp pain that started day 1. M 36 2 days
75 MG 1X day
3/30/2014
 1  Hypertension ED and loss of sexual desire Took for 12 1/2 years. Serious rebound when discontinued, tapered 1/2 dose for 2 weeks, the stopped. Still got lots of edema and some shortness of breath. Gained 7 lbs. while eating less and avoiding salt. Had to take some lasix a couple of times to control shortness of breath. After 3 weeks, still having some edema but off if for good. M 76
37.5/25 1X day
7/19/2012
 1  HBP ED/impotence M 35 4 years
25/37.5
11/22/2011
 1  Meneires Disease Worsening depression, strange patches of skin redness, extreme irritability, decreased sexual desire. At first I dropped like 10 pounds in a week which was a plus for me. But even with decreased sodium intake and watching my diet, I gained most of it back quickly. Then the depression hit and keeps getting worse, making me feel like I'm going crazy. Going to stop taking it. F 47 3 months
37.5-25 1X day
8/3/2011
Email
 1  At home I had very bad muscle cramps an head aches.I went into Dehydration. F 31 3 days
75/50 mg 1X day
4/21/2011
Email
 1  edema 7 lbs of water lost in 24 hours, i thought was extreme, then came intermittent muscle twitching (all over body) and severe muscle cramping. Could not move due to muscle cramps even though I drank plenty of water and Gatorade, ate bananas and had plenty of salt. Also had mild nausea and felt tired all the time. Doctor told me this was the mildest medicine for edema, and that I should immediately stop taking it and he would monitor the water retention. F 44 3 days
75-50 1X day
2/22/2011
 1  Hypertension Kidney failure, uric acid kidney stones, drug-induced Lupus erythematosus, rhabdomyolysis. If there is any family history of an autoimmune disease, mixed connective tissue disease, or kidney disease DO NOT TAKE THIS MEDICATION. F 56 10 years
37.5/25 mg 1X day
6/24/2010
Email
 1  For fluid rentention and swelling Unconsciousness, Rapid Heart Beat,Severe Swelling Of The Feet. Blood Clots almost Death. I Do Not Advise Anyone To Take This Medication. It Is Dangerous And Should Be Taken Off The Shelves. F 80 6 days
25mg 1X day
5/7/2010
Email
 1  hypertension The side effects were pulse rate of 95 - 110, sleeplessness, dehydration, nausea, muscle aches, frequent urination, high blood pressure, shortness of breath, My doctor prescribed maxzide to replace my normal diuretic, 25mg Hydochlorothiazide, to prevent potassium loss, due to mild dehydration. This medication further dehydrated me to the point I was unable to function. I quit taking it after 5 days and went back to my original medication. It took another 5 days for the symptoms to go back to normal and my blood pressure to go back to normal. Be very cautious when taking this medication and at the first sign of any problems stop. My blood pressure while taking this medication was as high as 160/105. F 61 5 days
7/16/2009
 1  hypertension Saturday: Itook 1/2 pill at 4pm last night. That night I was nausous; rapid heart rate and felt jittery. The next morning, I weighed myself and found out I had lost 4 lbs. Pharmacist said the dosage was too high for me and not to take any more until I speak with my dr. on Monday. M 63 1 days
1/5/2008
 1  for hypertension After taking a 1/2 pill dose of maxzide for 4 days, I abruptly lost consciousness while riding in the car. Fortunately, for me and the general public, I was not driving. I was picked up by ems, my heart rate was 40, not high enough to sustain consciousness. I just got out of the hospital, where I was given large iv doses of potassium because Maxzide had depleted the potassium out of my blood. I do not have kidney disease, as was just tested for that while in the hospital. DON'T TAKE IT!!! F 56 4 days
2/19/2007
Email
 1  hypertension I have MS which is a autoamune disease. I took Maxzide for 2 days and I had muscle cramps that is almost stopped me from breathing. I was taken to the hospital ER and almost died there. The product contains sulfa drugs and I wasnt told it did because the detailing sales person who pushes this drug in the doctors offices and wines and dines the doctors to prescribe it forgets to inform him of this compound that could kill someone if they are allergic. I dont know how much damage this drug did to my body but the doctor is refusing to contact me about how I feel. I almost lost my life on this drug. Test should be taken first before scripting it. It is not for everyone. F 56 2 days
12/9/2006
 1  Essential hypertension Muscle aches and cramps, kidney stones, renal (kidney) insufficiency. Although I was prescribed this drug in 1994, literature was not included with the precaution "Possible exacerbation or activation of systemic lupus erythematosus". I took this drug from 1994 through most of 2003 and at one point, under the direction of a world-renowned rheumatologist, was on 72 different tablets a day - all to combat the lupus brought on by the Maxzide. In 2003 an alert FNP advised me of this literature and I was taken off the Maxzide immediately. During the time I was on the Maxzide I sometimes prayed to die the pain was so great and I feel as though I lost nine years of my daughters' growing up, their most important childhood years. I am left with renal insufficiency, kidney stones and an impaired immune system. If you have history of ANY autoimmune disorder in your family medical history DO NOT TAKE THIS DRUG! F 51 9 years
4/12/2006
 1  diuretic for Meniere's disease After just 5 days, ended up in ER with low potassium. F 50 5 days
10/26/2005
 2  Ménière's Desease Lowering Potassium!! Jittery, headaches, Rheumatoid flares, high liver enzymes, vision problems I am already on 20meq potassium 4 times per day. Doc said this was the pill that would help me from having vertigo attacks and also bring Potassium levels up. Started with good Potassium readings of 4.7 which have steadily dropped to 3.3 and a whole load of problems besides those mentioned above. My regular Phys. Says the Maxizide is the culprit of Potassium and other electrolytes going down, liver problems, and other side effects. It is now 5 days since my lower dose of 1/2 pill (37.5-25) has been started. My potassium is going back up, but my Rheumatoid flares that began with the higher dose is getting worse. I am to look for fluid retention, but so far there has been none. My hands, however are getting very stiff. I have more blood work next week. I am afraid lowering the Maxzide is going to start my vertigo attacks again, but I can't live with lowering electrolytes and the other effects I was having. Just praying all holds steady soon! F 60 1 years
75-50
12/11/2014
 2  Hypertension severe erectile dysfunction - had none before taking this medication. Much worse that beta-blockers, which are generally not a problem (excepting atenolol). Abrupt withdrawal may cause serious rebound edema. Recommend a two week taper to withdraw. M 73 4 years
8/21/2009
 2  water retention Frequent urination, severe body cramps for 24 hrs . My doctor descided to give me maxzide ,rather than the diuretic I was taking before. The Doc is a good guy. But somewhere the fact I'm allergic to sulpha drugs, was lost. I took one pill on thursday afternoon and for 24 hr I was cramping everytime I finished urinating. It was a terrible exhausting experience. I immediatelly called my doctors office to let them know what happenned. Waht did I learn .....Google your meds.... before you take them. Than look for side effects. If had done so, I would have seen that people allergic tu sulpha drugs shouldn't be taking maxzide. M 50 1 days
5/6/2007
  

MAXZIDE  (HYDROCHLOROTHIAZIDE; TRIAMTERENE):  This drug is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is a combination of two "water pills" (diuretics): triamterene and hydrochlorothiazide. This combination is used by people who have developed or are at risk for having low potassium levels on hydrochlorothiazide. It causes you to make more urine, which helps your body get rid of extra salt and water. This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.   FDA Approval Date: 1988-05-13 (Sources: U.S. Centers for Medicare Services, FDA)

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