Drug Ratings for LUPRONAverage Rating: 2.8 (744 Ratings)
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Results are sorted by Age from youngest to oldest (no age reported listed first) Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
| RATING | REASON | SIDE EFFECTS FOR LUPRON | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
  | F M | | | | |||
| 4 | Fibroids, heavy bleeding | Hot flashes, pressure in my head, depression, menstrual cramps, sweating, increased sex drive, vaginal dryness, forgetfulness | I never had menstrual cramps before until I took this medicine. Sometimes I would be in intense pain, which would last for about 10 minutes. I haven't had a cycle for the last 2 1/2 months, which is good cause I had them twice a month before Lupron. The pressure in my head and dizzyness was almost unbearable, but has gone a way. I'm in my third month and some of the side effects are starting to ware off. I'm glad I took the medicine despite the side effects since it gave me a three month break from my heavy twice a month cycle. Hopefully I won't need surgery after the three months is up... | F | 27 | 3 months | 7/8/2009 | 4 | Severe Endometriosis | Hot flashes, some moodiness, decrease in sex drive, weight gain, some acne | I have been on the medication for over one month and feel great. I have gained some weight (about 3-5 lbs) and have some acne (but this may be a result of getting off of the birth control pills since I've always had bad skin). I have some hot flashes. I was so scared to take this medication after reading some patients' comments, but I truly feel fine. Hopefully this will one day give me an opportunity to have babies. HIGHLY recommnend asking your physician for add back therapy. I truly believe the pill I take once a day is the reason why my side effects are not as bad as some of the ones being experienced by others. | F | 27 | 1 months | 7/13/2009 | 3 | Stage 4 Endo | Hot flashes, night sweats, mood swings, anxiety, depression, edema | As my doctor warned my husband after I had lap surgery, Lupron can cause mood swings bad enough to cause a divorce in a seemingly happy marriage... THIS IS COMPLETELY TRUE. The mood swings I have are so sudden and drastic, it's like being a different person for 6 months. I neither recommend or caution against this medication, but you have to be prepared for what is to come! Please email me if you are experiencing these same problems, I would love to correspond with someone who understands! | F | 27 | 3 months | 5/13/2009 | 3 | Ovarian Cyst ( 4.9x6.4) | Extreme fatigue for first week following each injection, Occasional hot flashes and night sweats,insomnia, hip and lower back pain. Abdominal bloating. | I was very anxious prior to starting Lupron therapy. I could'nt find very much research on it's use for Ovarian Cysts. In the first month there was little to no change but I did still get a period and had almost constant pelvic pain like i was having period cramps all month. | F | 27 | 2 months | 6/16/2008 | 3 | Fibroids | Mood swings, minor depression, anxiety, hot flashes, acne, lethargy | Mood swings and anxiety throughout the whole treatment. No weight gain yet, but I am so stressed I am not eating properly. Hot flashes are extremely uncomfortable, especially in the summer. But I do feel that the fibroid has shrunk. First month had a 2 week long period, but since the second shot 2 weeks ago have not bled at all. | F | 27 | 6 weeks | 7/31/2007 | 3 | stage 3 endo | JOINT PAIN, EXTREME LOSS OF SLEEP, EXTREME MOODS SWINGS, HOT-FLASES, EXTREME DEPRESSION, MEMORY LOSS, ANXIETY | I STEPPED INTO THIS TREATMENT WITH WHAT I THOUGHT OF GREAT SELF CONTROLL. MIND OF MATTER IS WHAT I TOLD MYSELF. WELL, THATS IMPOSSIBLE IF YOU'VE LOST YOUR MIND. MY PAIN AND PERIODS WENT AWAY IMMEDIATELY AFTER THE FIRST SHOT. ALL ACCORDING TO PLAN BUT THEN THE SIDE EFFECTS CAME. HOT FLASHES IMMEDIATELY, EXTREME HUNGER, AND EXTREME ANXIETY. BY THE 2ND WK ON MY FIRST SHOT I WAS CRAWLING OUT OF MY SKIN. I DIDNT KNOW WHO I WAS. I WAS CRYING ALL OF THE TIME AND EXTREMELY ANGRY WITH THE WORLD. I HATED MYSELF FOR FEELING SO WEAK N NOT BEING ABLE TO CONTROLL THIS DRUG. I HIT A STATE OF EXTREME DEPRESSION AFTER 1 FULL MONTH OF NOT SLEEPING LONGER THAN 2 HRS A NITE. I RECOMMEND THAT YOU HAVE A GREAT SUPPORT SYSTEM AS YOU STEP INTO THIS TREATMENT. I WOULD NOT RECOMMEND THIS DRUG IF YOU HAVE HISTORY OF DEPRESSION. THIS DRUG HAS BEEN A HUGE RISK TO MY LIFE. IT KILLS YOUR SELF-WORTH AND STRENGTH. THE ONLY GOOD THING IS THAT MY STRENGTH TO SEE THE LIGHT AT THE END OF THE TUNNEL CAME ABOUT 2 MONTHS AFT | F | 27 | 4 months | 1/25/2009 | 3 | Stage IV Endometriosis | I've only been on the shot for a week now, but, side effects have been minimal so far. I'm also taking aygestin. Mood swing, "vein" pain in legs, wrist and finger pain (on a scale from 1-10, it's about a 2). | I decided after a lot of debate to start Lupron (for 3 months, injection once a month). I was recently diagnosed with Stage IV endo, with colon involvement. It's not IN my colon, but attaching aggresively to it. In an effort to save my uterus so we can have a baby soon, and, to hopefully shed some of the colon involvement to avoid a resection, I started a week ago. Like another poster here, I am also keeping a blog of my Lupron/Endo Journey. http://i-am-not-endo.blogspot.com. | F | 27 | 7 days | 4/8/2008 | 3 | Endo/Ovarian Cysts | Hot flashes, insomnia, bone pain, night sweats, insomnia, loss of appetite and weight loss | I have stage 4 Endo and am taking Lupron to shrink another cyst so I can avoid a second Lap in 6 months. I take one shot a month with no add-back therapy. The drug's side affects have been unpleasant and very hard at times, but it will be worth it if I can avoid going under the knife again. I am doing everything to minimize side effects. Get a fan for the bedroom and your desk...it will help the hot flashes and night sweats (and help you sleep). Take calcium supplements with magnesium to help bone pains and insomnia. Omega III Fish Oil is good for auto-immune diseases like Endo, and it helps with depression and joint movement that might be caused by Lupron. Lastly, regularly excersizing does wonders for the body and mind. Good luck to everyone and do everything you can to put up a good fight. | F | 27 | 6 months | 3/25/2008 | 3 | Endometreosis | Have yet to take Lupron shots, but considering it. Had Lapro in November 07. Prior to surgery had horrible horrible periods. Was in bed for three days out of the month once off the Bc pill because my husband and I were trying to get prego. It has now been 5 months after the surgery and my last period was not as painful as it had been before the surgery. However I do not want the pain getting as bad as it was. Do I follow my Dr advice and do Lupron for 6 mths or keep trying to get prego until the pain gets worse. I am tired most of the time and sick of this! Please help with any advice. | F | 27 | 0 days | 4/2/2008 | 3 | PCOS and Endometriosis | Hot flashes, night sweats, insane mood swings, depression, severe back pain | I began taking this drug to see if it would get rid of my constant lower right quadrant abdominal pain. WHile it has gotten rid of my period and the cramps associated with that, it hasn't touched the pain that my doctor and I were hoping to get rid of. When he was explaining the side effects to me, he only mentioned the menopausal effects (hot flashes, mood swings, etc). He made NO mention of any other effects. I've been on it for 4 1/2 months and am in more pain than ever. | F | 27 | 4.5 months | 10/23/2007 | 3 | endometriosis | Just received my first shot today and after reading all of the feedback I am scared to death. I did not want to take this medication but was told it was my only option for pain relief. I hope the side effects are mild and feel for all of you suffering so severly from this medication. | F | 27 | 1 days | 5/16/2007 | 3 | Endometriosis. | Hot flashes, cold flashes, horrible mood swings, depression, agitated easily, crying, trouble sleeping, extreme fatigue, weight gain, headaches, joint pain, stomach aches, decreased sex drive, vivid dreams, don't want to do anything but sit on couch or sleep. | I was put on Lupron a week after my 4th laproscopic surgery for chronic endometriosis (I have had one surgery per year since 2006), and my doctor said the next surgery will be hysterectomy. So he put me on this drug to prevent the endo from returning so quickly, trying to buy me some time to get pregnant one more time before doing hysterectomy. So I am currently taking this drug once per month for the next 4 months. I felt the side effects right after getting the injection. Cried for days with terrible mood swings and anger towards my poor husband. Once Monday came, I called the doc and requested something to help w/symptoms. He put me on Lexapro (for depression, mood swings, and hot flashes) and hormone therapy. So after just one week of taking these meds, I am feeling MUCH better, but still have trouble sleeping and hot flashes. Still feel very tired all the time. Still have headaches. But I keep telling myself it's only temporary, and I can get thru it. I would suggest you ask your doc for meds to help with the side effects before you get the shot, or the same day, as I waited a full week and my husband was thinking I was going insane and even slept on the couch. We never fight, and I have never called him a name before. And this drug made me a monster, taking everything out on him for no reason at all. I also have a therapist, so I made an emergency appt w/her and took my husband in with me to talk about how I need extra support and attention during this time, and it help | F | 27 | 2 weeks 1X M | 10/14/2010 | 3 | endometriosis | Joint pain, sleepiness, headaches, a little bit of nausea. | I was very scared about getting depression, as I have suffered from it in the past. Fortunately, I have not had that as a side effect. (at least, so far). I was VERY scared to start Lupron because of the possibility of depression. I actually started a blog to track my side effects and kind of keep a journal about this whole process. I hope it can help other decide if they want to go through it or not. The address is: www.mylupronjourney.wordpress.com I hope it can help! Good luck. | F | 27 | 3 weeks 1X O | 11/30/2010 | 3 | Endometriosis | Weight gain (10 lbs), headaches, fatigue, loss of sexual desire, mood swings, memory loss | This is my first time having to do this. I had my last shot June 2011 and it's been about a month now and no period yet. They said normal would be 2-6 months after I would start. I took Northendrone with it and finished that last week. I now have headaches and just not wanting to do much. I hope it was well worth it cause I do not want to do it again. | F | 27 | 6 months 1X M | 5/12/2011 | 3 | Endometriosis | HEADACHES, night sweats, severe fatigue, mood swings (but only a few severe so far), achy, less of a sex drive than usual. Some nausea too but I think that's just from the endo. The headaches and fatigue are definitely the worst. | I get my 2nd of 6 shots next week. I hope I survive 6 months of this. But it'll be worth it in the end. I'm also taking Aygestin to help with the side effects so I can't imagine what it would be like without it. | F | 27 | 1 months 1X M | 7/30/2010 | 2 | Endometriosis (Stage 4), IVF | HOT FLASHES!!!!!!!! | I have taken Lupron around 10 years ago for several months and remember to same hot flashes and waking up in the middle of the night sweating. Same thing for this time around. I am starting the IVF process in a couple of months and my Dr. wanted to slow the process of my endo/cycts/fibroids. I trust my doctor, hate the medication. I cannot wait to be done with my Lupron injections! | F | 27 | 2 months 1X M | 3/4/2011 | 2 | endometriosis | HOT FLASHES!! Heavy prolonged period, cramping, irritability, feeling of being angry at times, fatigue, pain in lower back, joint pain in hips, dizziness | It has been almost a month since my first injection and within the last week I have began to experience some not so pleasant side effects. I hope that this is just from the initial surge of hormones. I feel angry at myself for agreeing to take this shot and for how Dr.'s seem to disregard the true side effects of this medication. It is a waiting game. I do hope that things improve but for now I am not happy about how I am feeling. If things do get better as far as pain I am not sure that what I am experiencing at the present time is worth it. I may change my mind down the road but for now I am very disappointed with my decision to do this. | F | 27 | 30 days | 6/11/2007 | 1 | Severe Pelvic Pain, constant bleedn | EXTREME Bone and Joint Pain (been to ER twice since it is so bad...and P/C doc will not prescribe percocet for "knee pain" - Dr. Obudo-Ecklad of Kaiser Fairfield, CA), crutches barely help. Sleeplessness, Hot Flashes, added depression, weight gain, bloated. The bone pain is so bad though, that at times at night I have to get on the floor and use my upper body to drag my legs to the bathroom! | After 2 grapefruit size dermoids were removed from inside ea. ovary every period thereafter was worse then when I had those cysts. My periods last 1.5-3wks. Only treatment (besides B/C pills that did not help) has been Lupron from 1.5yrs ago until now. This summer I bled 5.5 out of 6.5 wks so I caved and took a 1 month supply. NO NOT TAKE THIS DRUG. My bone and joint pain is so bad that using crutches barely helps, I have to take percocet just to ease the pain. Added Depression, sleeplessness, hot flashes are all happening. My bone pain happened within hrs of the injection. Before getting it I told te GYN I didn't want it since other proclaimed their bone pain was unbearable, he (dr. Nystul, Kaiser San Diego)said I would NOT get that side effect since I was so young. Well guess he never takes the time to look on forums to see that about 18 out of 20 women are miserable from this drug and share similiar side effects. Worse part, the tiny side effect booklet says it can be IRREVERSI | F | 27 | 1 months | 9/18/2007 | 1 | endometriosis, ovarian cysts | night sweats, memory loss, anxiety, bone loss-osteopenia. bad back and hip pain. | Had lupron once a month shot for treatment of endometriosis( and hopes that is would help me get pregnant-dc said it would increase my chances after treatment). I did not initially experience really bad side effects (except for bad ovarian pain) but after the 4th shot it all went down hill - bad back and hip pain, night sweats, memory loss etc.. I went to doctor for bone density test (i ordered it myself) and now have osteopenia and taking a lot of calcium and vitamin D supplements each day (citracal with minerals). I had severe bone loss - hopefully I pray that it reversible!!! I was supposed to do 6 shots in total but needless to say I'm stopping with this one. This drug is not good and doctors really downplay the side effects when trying to get you on the drug. I can't wait for it to leave my system so I can be normal again. | F | 27 | 4 months | 2/7/2007 | 1 | Endometriosis/ovarian cysts | Hot flashes, severe and quick-onset depression. Breast tenderness/pain. | I have a history of chronic depression, and after reading a list of possible side effects talked to my doctor about my worries of onset of depression accompanying the Lupron injections. She quickly said I shouldn't worry and that there was really no chance of depression as a side effect. Within three days I have dived into a depression so deep I can't pull my thoughts away from suicide. Constantly. I'm aware this is the medication, but I WANT TO WARN ANY WOMEN OUT THERE: if you have a history of depression, BE VERY CAUTIOUS! This is the worst I've been in years, and I'm terrified. DEPRESSION IS A VERY REAL POSSIBILITY. If your doc brushes you off, GET A SECOND OPINION. | F | 27 | 5 days | 4/14/2008 | 1 | endometriosis | severe hot flashes, bone and joint pain and constant hip pain, "memory fog", weight gain, exhaustion, chronic migraines, trouble sleeping, depression | I wish I had listened to the other reviewers here. Lupron ruined my life. I went through all those side effects month after month thinking "maybe NEXT month it will help... maybe NEXT month..." but of course NOTHING. I am left with worse endo pain then ever, can hardly walk because of the lasting pain - my last shot was 3 months ago and I STILL don't feel normal - and I gained 40 lbs that I cannot seem to shed no matter what I do. Stay away from this drug!! | F | 27 | 6 months unknown 1X M | 3/20/2010 | 1 | Endometriosis | Depression Hot flashes Back Pain Mood Swings Anxiety Hair Loss Night Sweats Fatigue Memory loss | This was my second time on Lupron. It was a drastically different situation the second time around. I felt like I lost myself. Terrible depression and constant anxiety. I ended up on 6 medications in attempts to curb the side effects. I lost my job of 8 years and currently have no insurance. Because of this, I have not been able to see my doctor regarding the terrible back pain I have after being off of Lupron for 3 months. There are several petitions online to get this drug banned and/or properly researched. It has changed my life. Please do not take it! | F | 27 | 6 months 1X M | 10/9/2012 | 1 | Endometriosis | nausea, depression, cramping, severe hot flashes. others i can't think of. horrible stuff. | I did Lupron for 1 month back in December and am still suffering from occasional hot flashes. The one thing that made me stop after only one shot was the severe depression I experienced about 2-3 weeks into it. I had been diagnosised with PTSD about a year prior to this, but was on the verge of being admitted into the psych ward because of the severe depression and would not recommend this to anyone who has any history of depression at all. It has been a few months but I ruined about 4 bra's due to the excessive sweating from the hot flashes. I would rather take the pain than go through that ever again. | F | 27 | 30 days | 4/29/2009 | 1 | Endo | severe side effects such as severe mood swings, hair loss, and loss od sex drive. | F | 27 | 5 months | 7/12/2009 | 5 | Stage III Endometriosis | I had some hot flashing and night sweats, but it was sooo worth it! I was so scared to go on Lupron b/c of all of the horror stories I hear, but it was awesome. I am also very sensitive to hormones and can barely tolerate the moodiness from birth control. Lupron was actually better from me than birth control. I experienced less moodiness. I can't say enough good about this drug. Don't let people scare you. Everyone is different, but as a rule in general, people that are getting along with a medication aren't going to take the time to review it on the website. Go for it! | F | 28 | 6 months | 5/14/2009 | 5 | endometriosis | hot flashes, mild depression, mood swings, dry mouth and thristy. | I was diagnosed with endomitriosis years ago. Completely frightened by the throught of Lupron I did nothing for a few years. About 5 months ago my pain from endo was too much to bare. I talked to my Doctor extensively about Lupron and decided to give it a shot. We had decided to do a 3 month trial, one month at a time to monitor side effects. I recently had my fourth injection (over a 4 month period). To me the side effects are worth being pain free. It has helped to have an understanding, support system and Doctor who took as much time as I needed answering my questions. My doctor told me that the younger you are the less side effects you tend to feel (relates to how much estrogen your body is producing). | F | 28 | 4 months | 9/17/2008 | 5 | endometriosis | the only side effect that I have had from the Lupron shot is hot flashes, night sweats, and some vagnial smelling. | I was really scared about take Lupron from seeing the side effects that people have had especially on this site. I started my add back medication right away and at first I was a little crabby, and had spotting all the time I talked to my doctor though and she uped my add back meds and I was fine. | F | 28 | 6 months 1X M | 2/16/2010 | 4 | Endometriosis | I had extreme night sweats, hot flashes!! But nothing that I couldn't handle. At first I had joint [ain and heart palpitations. | I took the Lupron and had an honestly great experience with it. I had the occasional night sweats and hot flashes. But it was nothing to complain about. I also got these itchy rashes anywhere I'd get hot or the sun was on me....at times that was irratating. Well I was going to continue the drug but first needed a dexa scan(measure your bone denstiy- side effect of Lupron is bone deplition) . I currently have osteoprosis and osteopenia at age 28. Some of that could of been from when I was a little girl and being diagnoised with juvenille rheumationd arthritis whos knows???? The drug made me feel better though! | F | 28 | 1 years 1X M | 4/5/2011 | 4 | Endometriosis | At the very beginning, I had some fairly extreme anxiety, had trouble concentrating and also had hot flashes. | I began taking Lupron after I had major surgery in January for an endometrioma the size of a baby's head. It was attached to various organs in my body, but they couldn't just do a small surgery because they were uncertain what it was. I had NO pain and was extremely suprised when my gyno suggested that I get an ultrasound. I now have a "c-section" scar and no kids yet....but I was glad to hear it wasn't cancer. I was very reluctant to take the Lupron shot because of everything that I had read about teh side effects. I did start to get a little "crazy" teh first month and my doctor recommended that I try the shot along with Zoloft (an anti-anxiety drug). the combination of these two were unreal. It was the perfect balance. I was energized and actually lost 10 lbs, I didn't feel anxious, depressed, obsessive.....it was great. The only side effect that i had was hot flashes - but that wasn't a big deal to me. What I am more concerned with now is that i am off | F | 28 | 6 months | 8/11/2006 | 4 | Endometriosis | Headaches, Hot Flashes, night sweats, weight gain | I took the last shot of my 6 month treatment (1 shot/mo) of Lupron in November. I read a LOT of horror stories online prior to taking the drug, but decided that personally, I needed to try it because the benefits could have out weighed the side effects. For me, that was a smart decision. I was in such severe pain. I was on continuous birth control, I had surgery, I took narcotic pain meds, I had cystoscopies and was on the IC diet for months. To say the least, I had investigated other options. I will not down-play the side effects. They are not pleasant. But compared to what I was living with, they are a walk in the park. If you are having mild discomfort and pain from endo, or other issues, think twice before taking this drug. The side effects will probably seem horrific if that is the case. But for me, I will take all those side effects and an extra 30 lbs over the pain and disruption endo was causing in my life. It may be short lived now that the shots are over, but I would do it again if needed and if it will mean keeping all of my organs necessary to conceive. The add-back therapy is a must to keep the worst of the side effects at bay. My doctor was thorough in explaining my choices, and I made an informed one. I suggest you do the same for your own situation. | F | 28 | 6 months 1X M | 12/30/2011 | 4 | Endometriosis Painful Periods | a few night sweats, mood swings, no sex drive | In the first month I still had the painful period and terrible mood swings. I was beginning to wonder if it was worth it. The second month got a lot better. I am going on my third month. I was told by my ob/gyn that if I could handle this drug and all of the side effects, they would give me a hysterectomy. I have not gained any weight and the mood swings have gotten a lot better. I still feel like I want to cry. I noticed that it is always when I am technically suppose to get my period | F | 28 | 2 months | 5/22/2007 | 4 | IVF | I really haven't had any. Maybe a little hot flash once in awhile. Other then that, its been great. I was scared to start this since everyone keeps talking about the side effects, but I haven't had trouble. If I did though it would be well worth it to have a baby. I will do anything to get a bundle of joy. | F | 28 | 22 days | 12/26/2007 | 4 | Endo | hot flashes, dry skin, excessive thirst, acne, joint pain(knees) | I have completed my 6 month trial and have been mostly pain free. I was terrified after reading this site and some of the complaints from other users. Mostly I have had hot flashes in the nights, and I fix that with cold AC and a fan at night. I have been having problems with acne and excessive dry skin. For the most part I am very happy that I went ahead and used the medication despite the warning from this site. | F | 28 | 6 months | 8/30/2008 | 4 | endometriosis (severe) with crohn's | Extreme heat flashes, constant one after another, dizziness, nausea, horrible muscle cramping and muscle spasms in back and legs, insomnia, depression, crying spells, anxiety, bone and joint pain, urinary pain, itchiness, fatigue, "flu-like" feeling, some migranes, intolerance to heat and cold, vision changes, memory loss especially the first 3-5 days s/p injection. | I would get faint, extremely nauseated right after injection, I would have to sit in the OB/GYN's office for an extra 30 min. to an hour to ensure I wouldn't pass out while driving home. Has anyone experienced this? | F | 28 | 3 months | 3/4/2009 | 4 | Endometriosis | Hot/cold flashes, face swelling, acne and face blemishes, lower and upper back pain, pain in the shoulders and neck, nausea, irritability, headaches and now migraines, memory loss and short term memory, and mood swings | w/in the 1st mo I had really bad hot flashes, I tried to manage my body temp by wearing tube socks and short sleeve shirts. (sounds funny, but it worked for me esp. thru the winter season. I would have my fan on at my desk which also prevented me from sweating up a storm.) I had cramping the 1st 2 mos which have now subsided (thank god! b/c before then life was miserable. I couldn't do anything w/o being in pain which included walking,sitting, standing, etc. I got so stressed out I was depressed) Glad to hear I wasn't the only one out there dealing w/the same condition. I had my period the 2nd mo and during the 3rd mo I noticed my face swelled up and now I have acne. I got really bad lower back pain and then it moved up to my shoulders and neck. My headaches have gotten worse to the pt where I am getting migraines. Anyone else getting migraines? I have to take a separate med for my migraines so some of my side effects might be a result of this. The Dr. sd my headaches will only get wor | F | 28 | 6 months | 3/9/2009 | 4 | endometriosis | during treatment: constipation, hot flashes, acne, sleeplessness | Before Lupon, I had terrible nausia and cramping with my period. It was so painful I ended up in the ER twice. When I first got the shot, I was really sick and constipated an nauseated for about 2 weeks, during which time I was TERRIFIED at the thought of having this medication in my body for another 3 months. But it went away... and I felt FANTASTIC. I could go out with friends, go on vacation, make PLANS that did not hinge on the condition "...if I feel okay that day." My major side effects during that time were acne and sleeplessness. In fact, I did not sleep through the night for 6 months. THAT sucked, but was nothing in comparison to the relief I felt. Towards the end of the first 3 month shot, I started bleeding... and I bled for 5 weeks. I had to do estrogen add-back to get it to stop. The second 3 months shot was not as blissful, but I still felt a lot of relief. Again, when it started wearing off, I started bleeding, but that was only 8 days. It has now been a month since the shot wore off, and I still have some strange things going on. I am really tight in my abdomen and vagina. It is getting better, but it was painful at first. I had a headache for a few weeks that would not stop. That has gone away. Right now, I am having hot flashes. I think overall, my hormones are still just trying to adjust. We will see what happens! No matter what, I AM glad that I did it and had that 6 months of relief from my pain. Did anyone continue expe | F | 28 | 6 months | 11/12/2009 | 3 | Endometriosis/Ovarian Cysts | Weight gain, hair thinning, moodiness, occasional headaches | After removing ovarian cysts, my doctor prescribed lupron injections for the next six months. I just had my fourth injection, and the side effects continue to cause me grief. I can tolerate the hot flashes and mood swings, but the weight gain and hair thinning are very discouraging. | F | 28 | 4 months | 1/9/2010 | 3 | Stage IV Endometriosis | So far so good. I was told side effects may not start until second injection. | I have stage IV endo that has caused lots of physiological issues such as multiple blood filled cysts, a blocked fallopian tube, colon issues, and pain everyday when I wake up. I started going through the process of getting it removed so my husband and I can hopefully have a baby. I had a laparoscopic procedure but since endo bleeds so much and the issues with my colon and the endo growth, the dr. could only clean up one side. I'm on lupron for 5 months to slow the growth so he can hopefully clean up the other side and we can get pregnant. I've been scared to death to take this for years but I had my first injection 2 weeks ago and everything is going fine so far. I'm actually having cold flashes... kinda odd! I still have mild endo pain but I'll take that over some of the things I've read about on here any day. | F | 28 | 2 weeks | 8/1/2009 | 3 | Fibriods | Bone and Joint pain. Loss of Libido | It is very hard to read these descriptions of side effects that other women are having. I am very lucky since I have only had some bone and joint pain which has now subsided. This website worried me more then necesary. It really wasn't that bad. The loss of sex drive is a bit bothering but the pain from the fibriods will make up for that once they are all gone. Good luck to all and ask you Doctor any questions you may have before making your own decisions about this drug. Don't make a decision based on just these side effects that others are listing here. I talked to several women who took Lupron and they did not have side effects that were very bad at all. | F | 28 | 6 months | 11/19/2007 | 3 | Endo | None at this time. Today was my first injection. I am both nervous, and happy at the same time. I am concerned after all the research I did, but at 28 I feel this is better than my other option, which was hysterectomy. I am hoping the MAJOR side effects discussed on this site are something that I can handle. | F | 28 | 1 days | 4/15/2008 | 3 | Endometriosis | Hot flashes, night sweating, severe mood swings, depression. | I started taking Lupron two weeks after I had a laporatomy in December. I took six shots and told the doctor that i refused to take anymore. I was so moody and depressed that my husband was miserable, almost left me. I had to start taking Welbutrin for the mood swings after my second shot. All I did was cry. I took my last shot in May and did not get my first period since the surgery till August. AFter the period, I am having to take birth control non stop till I decide when I want to start having children. I would recommend the shots to anyone, but be sure you have a doctor that is very open with you and be there to answer your questions if you have one. If I had a question or problem, my doctor or his assistant always called me back and I did alot of research before I took the first shot. Also, I got some advice from some friends who had been on the shot and kinda knew what to look for. The only problem I am having now is that my legs and ankles started to swell in July. My left leg/foot is swelling worse than my right. I have been checked for several different things and nothing has been found. I am starting to wonder if it is a side effect for quitting the Lupron. If anyone has ever had this same problem after the last shot, please let me know. | F | 28 | 6 months | 9/10/2009 | 3 | endometriosis,ovarian cyst,pain | i get hot flashes and headaches weight loss night sweats mood swings | i like the shots but my case is so saveer that i need them sooner than once a month. My doctor wont give them to me sooner but it sure would be nice if she would. iv been living with ovarian and uterian pain since i was 10. since iv been taking the shots my pain has gone down and made my life a little more managable tell i have my hysterectamy | F | 28 | 9 months | 5/8/2005 | 3 | adenomyosis | muscle pain, severe headaches, hot flashes, night sweats, mood swings, weight gain | Lupron is not a wonder drug, as the manufacturer claims. It can be helpful in situations where other drug therapies have failed and the patient wishes to avoid or delay surgery. It has stopped the pain of adenomyosis (think labor pains) for me, so I cannot wholly discount the drug's usefulness, but anyone considering using Lupron should be well aware of all the possible side effects. I was warned of hot flashes and vaginal dryness, nothing more, and I now wish that I had taken the time to look into other possible side effects. The worst of the side effects for me are the muscle pains and awful headaches, both of which I might have been able to prepare for had I known they were coming. Also, sadly, the weight gain puts me further away from surgery than I was before I had the injection; if you are considering Lupron as a pre-surgical therapy, keep in mind that it can have adverse effects on your surgical risk factors. Lupron will likely do you some good if you are in pain due to hormone-driven diseases like endometriosis, adenomyosis or fibroids. However, I strongly suggest that you make sure you know exactly what you are getting yourself into before you take the leap of faith with an irreversible three-month injection. | F | 28 | 2 months | 5/14/2005 | 3 | fibroids very heavy bleeding | HOT FLASHES and mood swings mostly, I took 1 dose that last 90 days...I am only 30 days into it and now starting to notice some weight gain...but hope with some exercise I can get it under control. | After my shot the bleeding stop for about a week then was back on for about 2. I have been okay for about the past 2 weeks and hope it all stays gone until surgery in Dec. So far so good | F | 28 | 3 months 1X AN | 10/11/2010 | 3 | Egg Donor | I am experiencing spotting and some minor menstrual-like cramps and bloating. I'm not sure if the cramps/spotting are due to Lupron, or to Reclipsen, which is a birth control pill I also have to take. I have noticed spotting consistently for the past 3 months with Reclipsen but the Lupron did seem to make the spotting heavier, almost more like a light period. I do not get migraines normally so I haven't experienced anything like that on this medication. The side effects are a little uncomfortable but I'm still able to go about my day as normal. So far it seems like a tolerable level of mild discomfort to help someone have a baby. I have not noticed anything major and I expected the bloating, which is more of a "feeling" of bloating than anything physically visible. I have a healthy diet and exercise routine generally. I also eat a low sodium diet which I think helps reduce the bloating. | I am an otherwise healthy, fertile egg donor taking Lupron to stimulate egg production and coordinate my cycle with a surrogate mother. I rated it a "3" because I'm not taking it for my own medical/fertility reasons, but to help another couple. | F | 28 | 5 days 10 Units 1X D | 7/27/2010 | 2 | possible endometriosis | headaches, feeling crazy, crying spells, anger, not make that rage, growing sideburns, sensitive vagina (skin tears easily), fatigue. | I thought it was a bad idea to go through menopause at age 28 but after taking birth control pills everyday for months and then getting my period for 2 months straight, i decided to try it. i took my 1st 3 month injection at the beginning on december and am not sure if i should take the next one in march. i had sex for the 1st time in over a month, not because i had to desire to, but because i felt so bad for my boyfriend and it burned the whole time. i am tired constantly and hate everyone. i need energy to smile. i noticed my nose is getting wider too. did that happen to anyone else or am i crazy? i'm growing sideburns too which are freaking me out, it better not become a beard. the endo specialist in my area doesn't recommend surgery because it's not a guarentee that it will not come back again. he says stay on lupron for 6 months and get pregnant as soon as possible. not really ready for that. oh, also having hot flashes, but moreso during the day. insomnia big time. and anxiety at | F | 28 | 2 months | 2/2/2009 | 1 | Endometriosis | Hot flashes, anxiety followed by panic attacks, depression, mood swings, weight gain | I was the devil ! If my endometriosis comes back and I have such severe pain again I still will not take these injections again. All my doctor really told me was you wont have your period, you will have some mild hot flashes, and something briefly about bone loss. I did not get much sleep while on lupron. I could not control my moods. I feel like taking these injections has ruined my life. I should have not been allowed to make any decisions on my own while on this medication. After my injections were done my doctor stated " oh, they shouldnt have effeted you like that"! Now 2 months after 6 months of injections i am in therapy and on anti-anxiety medication. Not to say I didnt have problems before but man does this medication really bring the devil and everthing bad out in you and I felt like I couldnt control it. | F | 28 | 6 months | 11/10/2008 | 1 | endometriosis and PCOS | severe hot and cold flashes with hives, severe insomnia, servere muscle and bone aches,loss of muscle mass, depression, loss of appetite, weight loss, severe lowered immune system, severe irritability, fatigue, severe memory loss, dizzy spells | I would recommend that nobody does this drug. I was on this drug for a year and half. I almost lost my job and lost people who cared about me because I was not myself. Also a lot of people don't understand that it's not helping the endo, it's only masking the systems. I finally got of the drug and when I did the endo was worse than it had ever been. For anyone out there seeking treatment, I found a leading world specialist, Dr. David Redwine, and had surgery. He is absolutely against this drug. Since my surgery 5 months ago, I feel like a completely new person, he removed all the endo!! I still have side effectsf though from the lupron and have been told that this could last for a year or two. I still have not got my bone density back. I would strongly advise against this horrible drug!!! | F | 28 | 1.5 years | 2/6/2008 | 1 | ENDOMETRIOSIS | My side effects happen every month about 2 weeks out from my periond I would get very bad lower back pain. I could not stand it, it would feel as if someone was beating me in my back. then when my period came my back pain felt worse and then when my period came it felt like my insides were falling out. | Lupron is the most intense drug I have ever taken and would not take it again. I got the hot flashes right away, headaches, vomiting, hair loss, my mouth taste like pennies. My Doctor said she has never heard anything like this so she sent me to the ER to get lab work. The ER doctor said I was not an emergency so I had to leave. My doctor will not return my calls. I call every day atleast 5 times a day.. Hmmm must be nice to be a doctor to get paid the money they do and not follow thru. If it were up to me NEVER AGAIN. Im just lucky I have a paitent husband. Oh did I mention I can cry just like that. Think about what you are doing. all the research I did I should have not done this to myself | F | 28 | 2 days | 7/1/2005 | 1 | ENDOMETRIOSIS | Weight gain 60lbs, in one year and not able to loose, night sweats, hot flashes, mood swings, horrible acne | it has been almost two years since my course of treatment and none of the symptoms have subsided. I can't loose the weight i gained with it,which is 60 pounds. I have had horrible cysts acne wihtout any relief when taking rx for it. Night sweats every night, hot flashes. And the mood swings have reaked havic on my family. | F | 28 | 30 days | 8/8/2005 | 1 | endometriosis | chest/heart pains, severe joint pain, headaches, depression, exhaustion, hot flashes | please DO NOT TAKE this drug if you have other options an you are young. I had my laparomy in June and started lupron in July. at first I gained weight, but then I actually lost 3 pounds. I was ready for the side effects, but not for my cysts to grow back and for the pain to be the same after. I feel like it was a total waste, since probably I'll have to do surgery again. I still have bone pain (this was the worst)and I fell exhausted all the time. I just can not get my energy back, it has changed my quality of life. I have had chest/heart pains since receiving 3 months of shots for endometreosis. My Dr acted like the Lupron shot was no big deal, he said the the reviews that i read on the internet are not true and that he knows better, but he did not have a explanation for why my cysts reappeared during lupron. I changed my insurance in January and now I'm going to see a specialist at John Hopkins. Please investigate this drug before using it. I'm taking now DMI, folic acid, vitamins, fish oil, green tea, and avoid alcohol, chocolate and coffee as often as I can. | F | 28 | 3 months 1X M | 2/23/2011 | 1 | Endo | Feeling out of it,Dizzy, Headaches, joint aches, depression, moody, acne.. did I say depression?? | I am going back to my painful cycles, these side effects are worse to me because they are constant, not 2 weeks out of the month.. | F | 28 | 1 months | 6/22/2009 | 5 | Severe Endo and Tumor in uterus | I have NOT had a horrible experience with Lupron, I was so scared by all the info on here about all the side effects. I have just started my 7th month of treatment, I am doing 1 year of 3 month injectons. First few weeks were rough but everything was fine after that. I have a few hotflashes when I get the shots but they go away. I do have a lot of nightsweats, usually 2 or 3 a night, I also have lost my libido, thank god for some helpers in that area! I also take the add back and when I forget for a few days...you dont want to be around to see what happens! I did have a lot of joint pain for the first month, I could barely walk up the stairs. I started taking 1 tylenol arthritis for it and I am totally fine now. Some of the crummier side effects are the loss of sex drive and the vaginal dryness, and the weight gain. I just feel like Im a lardo all the time. But I am very happy I have taken this drug! Everyone reacts different, please talk to you Dr. and get all the details before sayi | My Dr. found a very large mass in my uterus and when he went in to take it out he also found that I had severe Endo. He wanted to do a hysterctomy right then, thank god my husband told him no way! ( we do not have children yet)after the Laproscope I started the Lupron Depot to help with the endo and to shrink the tumor so they can take it out. | F | 29 | 7 months | 5/27/2009 | 5 | Endometriosis | Joint Pain, weight gain, hot flashes | I was on Lupron in 2001 for my endo pain and i LOVED IT! My pain was gone and although the side effects weren't fun it was worth it. I had a son in 2004 and 2006. I started feeling endo pains last year and I talked to my doctor about another round of lupron. I just got my 1st 3 month shot this week and i am excited. Think about it - i got the shot in 2001 and started feeling pain again in 2008? Seven years of relief! Lupron is wonderful and I say try it! | F | 29 | 6 months | 10/9/2009 | 5 | Endometreosis | Hot flashes, painful sex, exhaustion, no period, bone loss. Side effects lasted for two years after stopping the medication. | This medication was a lot to deal with but helped a great deal. The hot flashes were not very hard to handle. The worst part was painful sex. I had painful sex before I started taking it anyway so it was worth it. After the two years of side effects wore off sex was enjoyable again and I was pain free. I noticed discoloration in my teeth though from the bone loss. A tooth whitener helped a little. It was an expensive drug. If I could go back and make the choice over again, I would still choose to take it. | F | 29 | 6 months Unknown 1X M | 2/10/2012 | 5 | endometriosis | Hot Flashes | I loved it! I just finished a 6 month course of treatment and it was the best six months ever. Usually I am kind of paralyzed with pain for about a week a month and it felt so good to go 6 months without having to deal with that. After the initial two weeks, which was full of cramps and heavy bleeding, I started feeling better and better. I would be on it for the rest of my life, but no doctor recommends that for someone so young because of the possibilities osteoperosis. The hot flashes were kind of intense for a few months but they were really no big deal. My friends would joke with me when they'd see me fan myself. I'd take hot flashes over cramps any day. | F | 29 | 6 months | 8/15/2006 | 5 | severe endometriosis | Swollen breasts and lower abdominal pain in the first couple of weeks. Since I got the second 3 month shot, I have been having hot flashes, joint pain, nausea, weight gain. Had to go to the ER one time for severe shoulder pain | My periods were so painful that I couldn't do anything and my prescription pain med wasn't working anymore. I had a lap that confirmed my doc's suspicions. didn't have a choice but to take the medication. | F | 29 | 5 months | 8/17/2006 | 5 | Severe endo | Mild fatigue, some memory problems, mild hot flashes | I took Lupron for 6 months after having surgery to remove a 15 cm endometrioma and several smaller implants. I also lost my right ovary. When I first heard about having to go on Lupron, I thought I was walking into a nightmare. Reading things about anxiety and insomnia scared me so much. The day of the appointment I refused to go, my husband had to drag me off the couch. I am so happy to say it wasn't nearly as bad as I thought it would be. Some memory foggyness, but otherwise manageable. I took the shots mostly in the winter, so I actually found the hot flashes pleasant ;) I just bought a lot of tank tops. My last shot was July, and I just got my cycle back this month (October). I feel a lot better and I know it worked to keep the endo at bay while my body healed, so hopefully I'll be able to have a baby soon I feel like me again, my energy is back- and I have to say that for some reason my anxiety level was waaayy down when I was on Lupron- things that normally made | F | 29 | 6 months | 10/20/2008 | 5 | Endo,pain relief, to get pregnant | Night sweats, headaches, body aches, lower back pain, hot flashes, flushed complexion, irritability, mood swings,severe acne.fatigue,bloating in the beginning,water retention. | Despite the side effects Im glad I did it.Is surely has been better than having surgery again (last surgery Apr'07). I feel really good about having a sucessful pregnancy this time and Im pain free.I had my last injection almost 2 months ago on Feb.15th and my period still havent returned yet.I would recommend it, so far it has been worth it.At my last doc appt he said my Endo on my bowls,bladder was minimum and my uterus was firm and that was good because it was tender back in October 2007. Ive read alot of bad reviews about Lupron but I guess I was one of the lucky ones because it was no worse than the pain and up and downs of my periods,PMS, and abdominal cramps. The only real drawback was that I developed ugly acne that Im working hard now to try and get rid of, I have lots of dark spots and a ocassional breakout now something I never had before.GOOD LUCK TO ALL!!! | F | 29 | 6 days | 4/16/2008 | 4 | Fibroids | Lengthier period with spotting and mild hot flashes, especially in the morning. I have aches, but I can't say if it's from the Lupron. | This has been the first month in a long time where I haven't had severe pain during ovulation and my period. I use to have to go to the bathroom between 5-9 times a night after I started ovulating, and now since I've taken the drug, I haven't had to get up at all during the night. | F | 29 | 27 days | 2/6/2009 |