LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Catemenial anaphalaxia Period didn't stop until two months after receiving Lupron. I have headaches, hair loss, palpations, difficult breathing, joint pain, extremely tired and depression. Not worth it. This was my first and last time on lupron. F 37 1 months
3 month
7/24/2012
 5  Fibroid,severe anemia,heavy cycles Bad hot flashes, a little difficulty with focus, sharper temper, but nothing unmanageable. Actually got rid of my migraines (life long sufferer) in addition to stopping a severe flow of blood that almost killed me. I plan to be on it 2 more months and hope to be in menopause by then. F 41 1 months
3.5 1X M
7/17/2012
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 5  Fibroids Hot Flashes mostly at night and slight headache at the beginning of my treatment. Not as bad as the comments on this site. Shrunk my fibriod from 26 week size down to 20 week size in 5 month pre-op. Everything went smoothly. F 45 4 months
4X M
7/15/2012
 1  Endometriosis Migraines, joint pain, rashes, fatigue, weight gain, sensitivity to light, weakened immune system, tachycardia, kidney stones, buldging discs in my spine. I've become overly sensitive to tons of medications that I was on for years, as well as foods. I may have developed an auto-immune disorder as well after having been on this medication. I'm not sure if the two are related or not but my symptoms didn't start until being on the medication for 3 months. If I had known what would happen to my body from taking this medication, I would not have taken it. I would have lived with the agony of my endometriosis. I have a very poor quality of life now. F 23 2 years
1X day
7/13/2012
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 1  endometriosis and fibroids was prescribed 6- stopped after 4. severe memory loss and adverse cognitive function, severe back injury (going on a month now - not healing, severe hyperpigmentation on my forehead and cheeks , was expecting the hot flashes and pms-like mood swings - got more than I bargained for. The cycsts and endo shrunk, but was just told that they'll most likely come back. All of this for merely a temporary fix with permanant side effects. Do I sue the doc or the drug co? I know this does work for some people...if you're trying to get pregnant - maybe it's worth it if you do. If you're not, I highly recommend against it. All it did was delay a hysterectomy which is foreseeably within the future. F 40 4 months
1X M
7/9/2012
 1  endometriosis I ended up being hospitalized from the side effects. I lost 25 pounds, vomited for 5 weeks straight, had to be feed through a feeding tube in my chest, had SEVERE panic and anxiety, body trembling so bad that medication like valium or ativan was the only way it would stop, very difficult to walk and make my muscles work, felt like I was going to die! This drug should be off the market NOW!! I am still having serious side effects after taking the drug back in 1996. My life has never been the same again. F 48 4 months
don't know 1X M
7/8/2012
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 4  Fibroids and heavy bleeding Hip pain, mood swings, hot flashes Lupron gave me back the ability to carry a child. I had over 20 fibroids of varying sizes. After a couple of VERY painful months, I miscarried prior to starting lupron. Now, after being treated with the injections, I am in the 2nd trimester with none of the pain or complications I experienced previously. This was not an evil drug for me. Though the side effects were very trying at the time, it has been well worth it to see a 7cm fibroid shrink to an undetectable size! Everyone is different. Give Lupron a chance. F 10 months
7.5 mg 1X M
7/5/2012
 1  ovarian cysts and poloystic ovarian Have only been on the drug less then 2 weeks. Have had increased symptoms not better, pain and problems with my medical condition worsen. the nausea is terrible I can not even look at food or cook for my family! fatigue is awful! I feel worse then I did before! i also have a history of mild depression and was never told that this can make it worse! help did anyone feel this right away Is it true your system speeds up before stopping the hormones from working? Have had to be hospitalized for the problem before the shot now I feel worse then I did in the hospital! My doctor canceled surgery swearing this was the way to go! god what did I do to myself! F 44 2 weeks
1X M
6/29/2012
 5  endo The side effects suck but the pain its worse F 26 4 months
monthly
6/17/2012
 2  Stage 4 endo EXTREME CRAZYNESS!!! I literally went crazy. Major anger issues. Wasn't myself at all. Some hot flashes and major night sweats. F 30 3 months
6/12/2012
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 3  Pain and pressure from Fibroids Absolutely batshit crazy disposition, 6 pound weight gain in first week, nausea, constant period. I decided to rate this after having had my shot for a couple of months.. I remember coming on this site directly after my first shot and getting scared out of my mind. I am sure everyone is different but I have had none of the horrible side effects some people have experienced. The thing that concerned me the most was my weight gain, no offense to everyone else but I took control and stopped the weight gain. First I got on the Add Back prescription, doubled my water consumption, and switched up my normal work out routine. I joined Crossfit and I am smaller then I was before the shot. The Add Back therapy seems to have fixed my crazy out of control behavior and moods (so bad my boyfriend and I did not survive).. I did experience a period for about 4 weeks and it was very painful but has sense gone away and I feel great. I will find out in a few months if it has shrunk the fibroid. I elected to try this first as I was not comfortable with the first suggestion of taking my uterus away.. I have had minor hot flashes but nothing too out of control.. F 40 3 months
1X M
6/2/2012
 3  Severe endometriosis Hot flashes, severe migraines, severe mood swings, trouble sleeping, night sweats, (I'm getting a period at 43 days into lupron. I'm not sure if that's normal. I haven't had one at all in a year and only spotted one day after lap and d&c.) F 25 2 months
1.75/month
5/28/2012
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 2  Endometriosis Severe night sweats and hot flashes, insomnia, memory loss, vaginal atrophy, constant urination, joint pain, minor rashes. Three months in, I told my doctor I would not be taking the second 90-day shot. She talked me into it and gave me an add-back, norethindrone. That helped significantly with all the symptoms mentioned above, but made my eyes very sensitive to light. When I started to have blurred vision, I stopped taking the add-back and am just dealing with the returned side effects. Am now one month beyond the 6-month period and praying the side effects will end. Would not take this drug if I had a do-over, but I was not in the excruciating pain described by many here; I was prescribed this drug in an attempt to avoid more endometriomas and inclusion cysts. F 49 6 months
5/28/2012
 3  Endometriosis Hot flashes, night sweats, mood swings, muscle pain, HORRIBLE back pain, zero sex drive, heart palpitations, dizziness, weakness, worsening memory, and awful headaches. I am on Lupron for treatment of Endometriosis. I had a laparoscopy in January and started my Lupron cycle right after my surgery. I am about to take my 5th shot (6 month cycle). I have debated for the last two months on whether I want to get the next shot. Since I don't know if it was the Lupron or the surgery that helped my original pain, it is hard to decide whether or not I'm willing to risk stopping it. The lack of a sex drive is causing serious strain on my relationship, and the other side effects are driving me absolutely crazy but not crazy enough to go back to the way I felt before. If anyone has found things that help the side effects, please email me. Good luck. F 24 4 months
1X M
5/22/2012
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 4  Fibroids Insomnia, night sweats I made the mistake of reading the reviews on this site right after I had my first shot and was scared to death of the possible side effects. But the only problem I've had is sleeping through the night. I waver between hot and cold all night and wake up every couple of hours. Other than that, I'm fine. No hot flashes, no mood swings, no weight gain. I exercise regularly and watch what I eat normally, so it hasn't been a problem. Even better, I do believe the medication shrunk my fibroids a little. Enough so that my doctor can remove them laparoscopically in a couple of weeks. Although I love not having a period, I am looking forward to the medication wearing off so I can get a good night's sleep. F 39 2 months
1X M
5/3/2012
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 3  Severe endometriosis, fibroids Weight gain (12 pounds in 6 weeks), achy bones and joints, headaches, forgetfulness, lower abdominal/back cramping (sporadic)...Thankful that my menses stopped, but not sure if it was worth the payoff. F 38 6 weeks
4/13/2012
 4  Severe endometriosis Mild hot flashes, weight loss, increase in sweating. Not bad at all for how much of my pain was reduced. Also, started injections immediately following laparascopy to remove some adhesions F 27 6 months
3.75
3/26/2012
Email
 2  to shrink fibroids I have taken Lupron for 4 uterine fibroids. But two of them have grown and the other two only decreased minimally. The effect after the first shot, was very heavy menses for 2 weeks plus with many tissues along with extreme tiredness. For the remaining treatment, i had continued fatigue, hot flashes throughout the day, depression and had to limit my walking. I know everyone has different reactions but i hope this information may help someone else. F 45 3 months
1X M
3/16/2012
 1  Ovarian cysts Extreme headaches, period started right after injection and continued for 10 days, had to have blood tests to make sure I wasnt anemic, no energy, no sex drive,clear discharge, nights sweats,loss of thoughts, insomnia, weight gain, achy bones, irritablility,spotting frequent, cycle still started again after 6 weeks (3 month shot). I also have found the I am getting colds often and it seems like my immune system is somehow compromised while using this drug. There were many cons and not enought pros to recommend this drug. The reason I was given Lupron was because I had suffered with Papladema and pseudo tumor cérebre in the past. I was afraid to take birth control because of that and to find that it can contribute to this ailment is alarming to me. I was supposed to get another injection last week and was sick so I didn't, thank goodness. I was dreading going through another ordeal with this drug. I am scheduling the hysterectomy. F 48 6 months
1X O
3/15/2012
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 5  Fibroids Hot flashes, especially intense at night. I, too, heard/read horror stories about Lupron but this was my last attempt at dealing with painful fibroids. I have a great MD who had great expereinces with Lupron, but still encouraged me to do research about the medication. I knew weight gain was a side effect, so I continued my running and was very careful with what I ate. I have to say I am very pleased with Lupron. The hot flashes are miserable, especially at night, but it beats the pain I was in prior to the protocal. I haven't had any issues with mood swings or loss of bone density, but I've always had dairy everyday and I take a calcium supplement as well. I can't say enough good things about Lupron. F 45 6 months
3.75 1X M
3/2/2012
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