LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Uterine Fibroids Hot flashes and flushing. White discharge (cottage cheese texture) after my 3rd and last shot. My rating choice is a 4, due to the fact that my period stopped after months of terrible bleeding, and I am ASSUMING that it is working. I will find out if the fibroids shrank when I go back to see my doctor. F 40 3 months
1X M
11/13/2015
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 3  Prostate cancer Memory loss, weight gain, joint pain shoulders, rash, poor sleeping, Extreme fatigue lasting several hours a day, emotional roller coaster, depression, mental confusion pre-osteoporosis, Loss of interest. Diagnosed at age 49. Gleason score of seven. I have had surgery and radiation treatments. Started at three months shots with intermittent therapy. I would hit the wall 5 to 10 days after getting the shots. Peeking after six weeks with the worst of the symptoms. I would gradually feel better until I needed to get my next shot. Extreme fatigue hit me in waves lasting several hours a day. Insomnia lasting 1 to 2 weeks as little as 1 to 2 hours of sleep a night. I am now on a six-month Lupron shot.The onset of my symptoms are more gradual and not as extreme as the three-month shot. Don't know if that is me handling sytoms better or the effects of the 6 month shot. I will be on the shot for the rest of my life. PSA did not go to zero this time and is doubling every three months. Do Not take getting this shotl lightly, it affects everybody in your family M 54 5 years
6X M
10/30/2015
 3  Prostate Cancer Severe joint pain,fatigue loss of muscle mass, weight gain, loss of strength. M 63 10 months
30 1X O
10/28/2015
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 3  Endometriosis Hair loss. Not to the extreme of bald spots but my once thick long healthy hair, is now long birittle and thin. Even 6 months after treatment. During treatment, extreme hot flashes! To the point where I froze my poor family out by opening the doors and windows in the middle of winter 24/7 and wore summer clothes to battle them. This was on top of hormone replacement therapy too! But lupron did help shrink my endometriosis significantly so my hysterectomy was a success. F 30 6 months
10/16/2015
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 5  IVF procedure Mild headaches in the PM. Noticeable skin thickening making it harder to get shots. That's really it. Super blessed and feeling great! I work, I work out, I take night classes, I do acupuncture once a week, and I am generally happy! F 28 3 weeks
10u
9/15/2015
 5  endometerosis Hot flashes, hair loss The shot helped me a great deal. I did not have any pain and was no longer bed ridden all the time. I feel like it gave me a new lease on life and hair loss and occasional hot flashes were a small price to pay. As soon as the end of my 6th month, my cycle came back along with cramps. Wish I could stay on lupron longer. F 32 6 months
9/12/2015
 2  Stage 2 Prostate Cancer Hot flashes (up to 2X per hour)--causing poor sleep; loss of libido, weight gain (+10 lbs), breast growth, reduction in physical endurance--even with weight training, 40% higher cholesterol; high ALP and VERY HIGH (130) GGT--indicating liver problems. Took two 3-month Lupron shots as part of proton beam therapy (two months prior, two months during, two months post radiation). Was glad to get the first one to stall progression of Stage 2 prostate cancer, but dreaded getting the second one. No apparent effect from the first shot during the first three weeks (was beginning to wonder if they gave me the right shot), then libido started to drop fast in the fourth week and frequent (up to 2X per hour) hot flashes started--which are a nuisance in the daytime, but debilitating for sleep at night. The second 3-month Lupron shot timed out three months ago, but the hot flashes are unabated, libido is coming back very slowly, and it is very hard to shed the ten pounds I gained while on the drug. The combination of proton treatment and Lupron has resulted in my last three post-treatment PSA tests coming in at .1 (5.4 pre-treatment). My latest lab report, however shows a 40% increase in cholesterol and a very high GGT reading of 130 (65 is the upper limit), meaning my liver has been damaged. I had no idea when I agreed to take the drug that liver damage would be part of the deal and the hot flashes and loss of libido would continue for at least several months past the end of treatment. M 58 6 months
1X O
9/3/2015
 1  Fibroids on Uterus Only 1 side effect was noticed and that was with the 3rd injection of Lupron. My hair started falling out in the shower by the handfuls and continued to fall out for 1 year following injections prior to my Hysterectomy. My surgeon never told me about this side effect, and if he had, I would have refused to take it, regardless of him wanting to shrink the Fibroids before surgery. The hair loss has been devastating. I once had the longest, thickest, most healthiest head of hair. My surgery was in September of 2011 and my hair has still not returned. I have to wear hair pieces, due to the shortness in my hair in my bangs, and the length as well. I had bald spots everywhere. I feel embarrassed now, and not attractive at all. DO NOT recommend this for any woman out there. You will regret it. I have tried everything, but nothing has worked so far to bring my hair back. F 50 3 months
1X M
8/24/2015
 1  prostate cancer My testosterone level went to zero. My series of injections have ceased six months ago and I am having horrible bouts of flashes and sweats.I am always depressed and moody. I feel like just crying for no reason at all. I am up at night every two hours to urinate but it takes all my strength to crawl out of bed. I haven't had any sleep for over a year.My Urologist said it will take up to a year for my T-levels to return. That means I have another six months on this he'll to go through. If it wouldn't be for my family I would have ended my suffering long ago. I wish I would have taken my chances with the prostate cancer. I wish I would have gotten a second opinion. I feel for all of you that are suffering like me. M 68 1 years
3 month in
8/12/2015
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 1  Cancer preventative!!! Hair loss.. Hot flashes..forgetfulness... Migraines..incontinence.. It's been five months and still have hair falling out daily.. Other side effects have cleared up.. F 51 5 months
7/16/2015
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 5  For severe endometriosis Hot flashes here and there. Occasional night sweats, a few head aches. And some staining. This was my third round of lupron since I was 25. I've had two healthy children in between the second and third round. It helped greatly with the pain and I had normal periods till after my second son. My endometriosis came back full force. Started lupron again in August of 2014 and have been great ever since. The hot flashes and head aches are worth it to get rid of the pain that would keep me from getting out of bed. F 32 6 months
7/15/2015
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 3  Fibroid Tumors Hot flashes, mild headaches, dry skin, small rash on arm I admit I was terrified of getting the three month shot after reading the side effects that others were having. I am entering my third month and so far so good. I do experience the hot flashes but they are nothing like I was expecting. Just a warm flush and it's over. There was some pain at the shot site but that eventually went away. I have experienced headaches but nothing life altering. I am a marathon runner so I can't tell if my aches and joint pain are from the medication or the running. Either way it's bearable. I normally don't write reviews but I felt it was important to give a moderate view to someone who may be researching this drug. One word of advice would be to inform family and friends that you are taking this medication so that they are aware of any strange mood swings. I even told my boss. So far I haven't had any but I have had a few funny moments of memory loss. Again not life altering but I am more dependent than ever on my smart phone. F 45 3 months
not sure 1X M
6/10/2015
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 2  endometriosis Hot flashes night sweats nauseating weight loss headaches rest less and cravings...... I stoped the shot on jan 23 2015 it ran out March 23 2015 and I still have no monthly. No good F 19 6 months
11.25
5/28/2015
Email
 4  endometriosis None so far I can't say anything about helping with pain, because for the most part I never felt any pain. What my doctor thought was that I had 3 cysts with endometriosis. It would be a simple laproscopy to remove them and the endo, because I never had heavy bleeding or severe cramping. When he opened me up it was a horror show. Stage IV endo with everything stuck together. I ended up needing a laparotomy. He could not believe I functioned with normally. Because I have Epilepsy add-back is not an option. I'm praying I won't end up with horrible side effects, but after seeing the pictures of my insides I know I need to put my big girl pants on and deal with it. F 42 2 months
3.75 mg
5/23/2015
 4  Endometrial mass The first few months were great then the hot flashes kicked in. By month three I have been experiencing hot flashes so bad that it's disrupting my sleep. I just got my fourth I injection and my mood has taken a serious turn for the worst. My cycles have stopped now, though, and I'm not experiencing grave bloating and pain like I had been. While I am no longer having severe menstrual cycles and pain like I was experiencing, the hot flashes have been difficult to manage. Within the last two weeks my mood has been horrible, I am experiencing severe nausea/dizziness and the hot flashes are becoming intolerable. My lack of sleep is definitely not helping my mood and my energy level is at an all-time low. While I am not experiencing as much pain during intercouse, I am still feeling some discomfort. I am on a 6-month plan and have 2 shots to go--and i am definitely looking forward to being done with this and not looking forward to menopause. That's for sure! F 41 4 months
1
5/9/2015
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 4  Prostate Cancer Most common ones especially joint and muscle pain in shoulders. These symptoms are much worse with 6-month injection than with 3-month When muscle pain is real bad I can reduce it by forcing myself to relax the muscles and deep, slow breathing. Aerobic exercise helps. Running, fast cycling, and cardio machines at gym. I often don't feel like exercising but force myself to get going and the energy follows. I always feel better during and after exercise. M 62 300 days
45 1X O
4/29/2015
 1  Endometriosis and cysts Hot flashes, mood swings, migraines that last for weeks, pain that feels like the flu, my skin hurts, I can't do much but stay in bed. My stomach is in knots. I have diarrhea. This is awful. I sure hope it is worth it in the end. Had shot in Jan, Feb, March and my last one that lasts 3 months in April. I feel like crap. I think dealing with my menstrual cramps would have been easier. F 39 4 months
4/26/2015
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 1  Endometriosis Bone and Joint pain, Nausea, Dizziness, Blurred vision ,sore Muscles, No sex drive, Headaches, Hot Flashes, Strange numbing feeling in my head that I now have to see a Neurologist for, mood swings ,Heart palpitations , heart racing. F 44 2 months
1X O
4/24/2015
 5  prostate cancer Hot flashes,joint pain,weight gain,fatigue Side affects are better than the alternative , spreading cancer M 60 6 months
4/2/2015
 3  Endometriosis and uterine fibriods I have been on the 11.25mg 3 month injection of Lurpon for four years continuously. I have experience excessive weight gain (40+ lbs), severe joint pain (my hips throb daily making it difficult to walk and do daily tasks), insomnia, and extreme fatigue. My pain associated with endometriosis has gone down immensely, but I have experiencing horrible side effects of the injection. F 26 4 years
11.25 1X M
3/23/2015
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