LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Stage 4 prostate cancer Hot flashes , pelvis testicular pain. Fatigue,depression, no sex drive , E D No sleep. Loss of muscle mass Weight gain Ruined who I was and wonder if I will ever be the same M 73 6 months
3/12/2017
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 1  To shrink Endometriosis cysts Where to begin... hot flashes, night sweats, insomnia, complete loss of libido (like I wanted to vomit when my fiance was trying to kiss me), extreme fatigue and depression, weight loss (I am already barely at an acceptable weight and I lost weight and have not been able to gain it back even after over a year of being off of it), nausea, digestion issues (I don't seem to fully digest any food anymore and my poop is never formed since being on this - again, symptoms have not resolved after being off for over a year!), my endometriosis pain was better while I was on it but I believe it ultimately made the disease worse because now I have pain in more places and more often than I ever did before. DO NOT TAKE THIS DRUG!!! It has severe long-term consequences to your health. My hormones still will not balance, my digestion is messed up, I still have no energy and can't do anything after work due to exhaustion (I used to never want to sit still and watch TV and now that's all I can manage), I have completely overhauled my diet and am working with functional medicine doctors to try to detox my poor body from this horrible death drug and even with all of that my recovery sucks and is slow. Hopefully my horrible experience will save someone else from having to go through this. Endometriosis can be treated naturally without having to deal with these debilitating side effects! DON'T DO IT!!!!!! F 30 6 months
1X M
2/28/2017
 4   I had major hot flash and night sweats. Also couldnt stop eating and gained 20 pounds. The worst part was the weight gain because each month i put on like 5 pounds. However i stopped bleeding after the second shot and had little to no pain the rest of the time i was on the shot. We will see how it goes off the shot. F 22 6 months
2/26/2017
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 1  Prostate Camcer Fatigue, muscle pain in legs, depression, shrinking genitals, - this all happened with the three month shots. Just this past month they started giving me six month shots - REALLY WEIRD IMPACT ON THOUGHT PROCESS. Tonight I was telling my wife about a dream I had. Once I finished the story it suddenly hit me that what I described as a dream really happened. I WONDER IF THIS IS RELATED TO LUPRON AND THOUGHTS? I WANT TO DISCONTINUE THIS MED. M 67 1 years
1X O
2/1/2017
 5  Uterine Fibroids, anemia For the first two days after the injection I experienced dizziness. Once or twice a month I had headaches, and needed to take Tylenol to help with those. The hot flashes are so far mild and manageable! I like this option better than Fibristal which I tried for a year (3 months on, 2 months off). I don't have to remember taking a pill every morning and I don't have the side-effects I had from Fibristal. I am very happy with Lupron. I told my doctor that I am not sure if it is just a psychosomatic side-effect, but I feel energized with the shots. I feel very fortunate that I am tolerating this drug so well. So far I have only received 2 injections, the third is due in 4 days. My doctor has prescribed enough for a year and the plan is to do at least 6 months. It has stopped my bleeding and I am hoping it will also shrink the 3 intramural/subserosal fibroids. I am also hoping that once I stop the injections, the artificial menopause will turn into a permanent one. F 52 6 months
1X M
1/30/2017
Email
 1  Severe endometriosis After being diagnosed with stage 4 endometriosis in 1994, doc prescribed Lupron, a new medication for women, back then, 22 years ago. It is chemotherapy, not meant for anything other than to weaken the immune system and cause so many other health problems, such as fibromyalgia, reduced libido, joint pain, ademyosis, infertility, and migraines. This drug stays in your system the rest of your life!! Do not let your doc force you to take it no matter what!! It made my endometriosis worse, and after earning 2 college degrees, was only able to use them for a few years until I had to go on permanent disability for the rest of my life because of Lupron. I am currently in bed most of the time on 6 medications for pain and muscle twitching, so I rarely get outside or motivated to do anything. It's really horrible. Don't do it, your doc is only prescribing it because they get a bonus from the pharmaceutical company for each dose they prescribe!! It's the worst drug ever. They might as well call it the shot of death, because that is what you will wish for once you take it. F 48 6 months
6 shots
10/1/2016
 1  Prostate cancer Excruciating testicle pain M 73 4 months
9/12/2016
 1  prostate ca. EXTREME FATIGUE and pain in shoulders/ back of legs just before the fatigue hits, when it comes on I can't walk 10 feet without have to take a deep breath and sit down,loss of libido ( I was a very active man for treatment (I also had 45 radiation treatment) but after the 3rd shot, I couldn't take the extreme fatigue anymore so I stopped taking this treatment- it has been 6 weeks since my monthly injection and still feeling the same. The doctor says it takes at least 3 months for the lupron to leave your system. I would NOT recommend the drug to anyone until the do a thorough research of possible side effects - there must be an alternative. For me Side effects are life changing and I am hoping that the doctor was right in telling me it will take 3 months for the LUPRON to wear off M 73 3 months
30 mg 1X M
8/29/2016
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 2  Prostate Cancer 1) Total loss of libido and sexual function within the first month-persisting for several months post-treatment; 2) Shrinkage of testicles and penis; 3) Breast growth; 4) Brutal hot flashes (2-3 times per hour, 24/7, as if your internal thermostat has gone haywire--lasting for another four months post-treatment; 4) Liver damage (GGT spiked to double upper limit w/o alcohol intake--slowly recovering with aid of milk thistle); 5) Cholesterol spiked 50% under same diet and daily exercise--slowly normalizing; 6) Onset of anemia with careful diet and daily exercise--slowly normalizing; 7) Vision impairment; 8) Sudden onset of fatigue--as if I could not stay awake for one more mile; 9) Much slower beard growth and loss of body hair; 10) Poor sleep at night and general lethargy during the day. Am not suggesting, as many, that this drug be banned. Some people really need this type of drug. I am simply asking that the manufacturer and information sources accurately reflect common side-effects and issue proper warnings. M 59 6 months
2X O
8/16/2016
 1  Endometriosis Brain fog, Intense hot flashes, Bouts of rage, Change in body odor, Inability to control reactions & emotions, Weight gain (70 pounds in 6 months), Susceptibility to further weight gain, Inability to lose weight, Abdominal pain & hernias, Increased stomach fat, Irrational mood swings Many symptoms resolved within 3-6 months of ending treatment. Body odor resolved eight years after ending treatment. Inability to lose weight is still on-going. Saliva testing shows long-term hormonal imbalances seven years after ending treatment. Weakened abdominal walls leading to hernias on both sides. No reduction in endometriosis symptoms while using drug. F 25 6 months
6/19/2016
Email
 5  Prostate Cancer Hot Flashes like you can't believe. Sex life is gone. Joint Pain. No Energy, 5 lbs of bacon slapped onto your lower stomach. Armpit Hair Gone (no biggie). It's a miracle to get 2.5 hours of sleep without waking in a sweat. One episode of double vision for 5 minutes that may or may not be caused by Lupron, who knows? I had high Gleason scores but non-metastasized cancer. In 3 months my PSA went from 5.7 to .2, so I have to say it works. But the doctors want me on it for at least a year if not longer. My next shot is coming up and I'm in the middle of 9 weeks of radiation. There is no way in hell I will take another shot of this poison beyond the next one. 9 months is plenty of time, I don't think doctors appreciate or care about how devastating this poison is on a human being. If you've got stage 4, I understand, but high Gleasons without mets that respond so quickly, should in my opinion, get treated for a shorter time. Good luck to any that need to be on this. M 64 6 months
1X O
5/22/2016
 1  Prostate Cancer Loss of muscle, cellulite in thighs, depression, zero sex drive, testicular shrinkage, more depression, anxiety, paranoia, ED, even more depression. Shed a lot of tears and lost a lot of friends. I felt like I was losing myself and becoming someone else (with no way back to me). I wanted to refuse the shot after 4 months but I let them talk me into another 3 months. I refused any more injections after 7 months. I felt like I was already dead so what was I hoping to save? I think it has done permanent damage to my brain. Ask more questions and be skeptical of vague answers regarding this drug. It has no curative quality, just delaying. How much time will it add to my life? Hard to say. How long will impotence last? Hard to say. Forever? Hard to say. How long will I take the drug? Hard to say. Is it damaging my brain? No statistical evidence is available. Will I ever see a brighter day? Hard to say. I wanted answers about me, not statistics. Even on the WWW I can never find anything but vague answers veiled with meaningless statistics about the effectiveness and the side effects from taking this drug. Have doctors become just statisticians now? M 60 7 months
3 mo shot 1X day
4/26/2016
 1  Pelvic Pain/Endometriosis Severe hot flashes, Fatigue, weight gain (20 lbs), Short term memory loss, Severe joint pain (in SI, hips, ankles, wrists, and shoulder joints), nerve pain, depression, breast pain, and loss of sex-drive. Si and hip joint pain is chronic beginning with the Lupron injections and still continues now (1-1/2 years after the last injection). Lupron has ruined my quality of life. I suffer chronic pain every hour of every day. Before Lupron I was fit, healthy, and vivacious. I have been abused and robbed by this poison. Lupron did not resolve my pelvic pain issues, they came back after the drug was out of my system. I ended up having an hysterectomy anyway. F 47 6 months
3.75 mg 1X M
4/12/2016
Email
 5  Stage 4 prostate cancer PSA 60 Hot flashes in the late evenings I was diagnosed with stage 4 prostate cancer and the cancer had spread to my lungs and lymph nodes. I took 1 month injection for 2 months then a 4 month injection. After two months, my PSA went from 60 down to 0.4. I remained very active and my energy level never decreased either. I am also juvenile diabetic and Lupron did NOT effect my diabetes. I would highly recommend Lupron. It had very little side effects for me and left NO permanent damage like chemo and radiation do. People need to listen to me. THIS STUFF WORKS!!! M 57 6 months
2/1/2016
 4  prostate cancer Little fatigue Hot flashes M 65 3 months
22.5
1/18/2016
Email
 3  Endometriosis Migraines, severe tiredness, weight gain, changes in mood, nausea This drug helped my endometriosis almost instantly. I was in constant severe pain all the time. I had pelvic pain and more often than not felt extremely bloated and uncomfortable. Lupron has helped in that regard; however, the side effects do stink. I already suffer from migraines - this drug makes them worse - so much so that I might have to discontinue after this month because I'd rather have the endo pain than a migraine. In the beginning, I felt nauseous all the time, that has decreased. I've gained about 5 lbs in only 2 months. For the most part, my moods are fine, but I've been more down lately. Not sure if it is related to the lupron or not. Still might continue with it, but it is not for everyone. It took me a year to finally agree to take this drug and I am still unsure if I made the right decision. F 34 2 months
1X M
1/14/2016
 1  Breast cancer hormone treatment F 47 5 years
4X O
12/1/2015
Email

Patient History
 5  Prostate Hot flashes ,joint and muscle pain,loss sleep,short memory loss, anxiety, Stage 4 cancer controlled by this drug that is why I am satisfied. Not many options for me that might be worse or better. Has kept me from a predictable lifespan sofar M 58 2 years
4 month
11/23/2015
 1  breast CA severe bone & muscle pain:severe memory problems,anxiety& depression.short of breath:decrease vision:mood swings:major weight gain:hot flashes I was already in full blown menopause,did not need it.dr. lied about many things,said main side effect hot flashes:with all the complaints for decades why is it still being given? F 47 5 months
not sure
11/23/2015
Email
 3  Pelvic pain Ive been on depo Lupron for the past 8 month, 1 injection every 4 weeks. Although the pain has stopped, I'm having hot flushes, around 7 in a day, insomnia, mood swings, awful chest pains and breathlessness and the weight gain! Is it worth being pain free for all these side effects? F 28 9 months
30mg
11/16/2015
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