Drug Ratings for LUPRON

Average Rating: 2.8 (769 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
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    Charts & graphs: Reviews Summary for LUPRON  | Top 10 Adverse Effects (reported to FDA)

RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
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 1  endometriosis and fibroids was prescribed 6- stopped after 4. severe memory loss and adverse cognitive function, severe back injury (going on a month now - not healing, severe hyperpigmentation on my forehead and cheeks , was expecting the hot flashes and pms-like mood swings - got more than I bargained for. The cycsts and endo shrunk, but was just told that they'll most likely come back. All of this for merely a temporary fix with permanant side effects. Do I sue the doc or the drug co? I know this does work for some people...if you're trying to get pregnant - maybe it's worth it if you do. If you're not, I highly recommend against it. All it did was delay a hysterectomy which is foreseeably within the future. F 40 4 months
1X M
7/9/2012

 1  endometriosis I ended up being hospitalized from the side effects. I lost 25 pounds, vomited for 5 weeks straight, had to be feed through a feeding tube in my chest, had SEVERE panic and anxiety, body trembling so bad that medication like valium or ativan was the only way it would stop, very difficult to walk and make my muscles work, felt like I was going to die! This drug should be off the market NOW!! I am still having serious side effects after taking the drug back in 1996. My life has never been the same again. F 48 4 months
don't know 1X M
7/8/2012
Email
 4  Fibroids and heavy bleeding Hip pain, mood swings, hot flashes Lupron gave me back the ability to carry a child. I had over 20 fibroids of varying sizes. After a couple of VERY painful months, I miscarried prior to starting lupron. Now, after being treated with the injections, I am in the 2nd trimester with none of the pain or complications I experienced previously. This was not an evil drug for me. Though the side effects were very trying at the time, it has been well worth it to see a 7cm fibroid shrink to an undetectable size! Everyone is different. Give Lupron a chance. F 10 months
7.5 mg 1X M
7/5/2012

 1  ovarian cysts and poloystic ovarian Have only been on the drug less then 2 weeks. Have had increased symptoms not better, pain and problems with my medical condition worsen. the nausea is terrible I can not even look at food or cook for my family! fatigue is awful! I feel worse then I did before! i also have a history of mild depression and was never told that this can make it worse! help did anyone feel this right away Is it true your system speeds up before stopping the hormones from working? Have had to be hospitalized for the problem before the shot now I feel worse then I did in the hospital! My doctor canceled surgery swearing this was the way to go! god what did I do to myself! F 44 2 weeks
1X M
6/29/2012
Email
 5  endo The side effects suck but the pain its worse F 26 4 months
monthly
6/17/2012

 2  Stage 4 endo EXTREME CRAZYNESS!!! I literally went crazy. Major anger issues. Wasn't myself at all. Some hot flashes and major night sweats. F 30 3 months
6/12/2012
Email
 3  Pain and pressure from Fibroids Absolutely batshit crazy disposition, 6 pound weight gain in first week, nausea, constant period. I decided to rate this after having had my shot for a couple of months.. I remember coming on this site directly after my first shot and getting scared out of my mind. I am sure everyone is different but I have had none of the horrible side effects some people have experienced. The thing that concerned me the most was my weight gain, no offense to everyone else but I took control and stopped the weight gain. First I got on the Add Back prescription, doubled my water consumption, and switched up my normal work out routine. I joined Crossfit and I am smaller then I was before the shot. The Add Back therapy seems to have fixed my crazy out of control behavior and moods (so bad my boyfriend and I did not survive).. I did experience a period for about 4 weeks and it was very painful but has sense gone away and I feel great. I will find out in a few months if it has shrunk the fibroid. I elected to try this first as I was not comfortable with the first suggestion of taking my uterus away.. I have had minor hot flashes but nothing too out of control.. F 40 3 months
1X M
6/2/2012

 3  Severe endometriosis Hot flashes, severe migraines, severe mood swings, trouble sleeping, night sweats, (I'm getting a period at 43 days into lupron. I'm not sure if that's normal. I haven't had one at all in a year and only spotted one day after lap and d&c.) F 25 2 months
1.75/month
5/28/2012
Email
 2  Endometriosis Severe night sweats and hot flashes, insomnia, memory loss, vaginal atrophy, constant urination, joint pain, minor rashes. Three months in, I told my doctor I would not be taking the second 90-day shot. She talked me into it and gave me an add-back, norethindrone. That helped significantly with all the symptoms mentioned above, but made my eyes very sensitive to light. When I started to have blurred vision, I stopped taking the add-back and am just dealing with the returned side effects. Am now one month beyond the 6-month period and praying the side effects will end. Would not take this drug if I had a do-over, but I was not in the excruciating pain described by many here; I was prescribed this drug in an attempt to avoid more endometriomas and inclusion cysts. F 49 6 months
5/28/2012

 3  Endometriosis Hot flashes, night sweats, mood swings, muscle pain, HORRIBLE back pain, zero sex drive, heart palpitations, dizziness, weakness, worsening memory, and awful headaches. I am on Lupron for treatment of Endometriosis. I had a laparoscopy in January and started my Lupron cycle right after my surgery. I am about to take my 5th shot (6 month cycle). I have debated for the last two months on whether I want to get the next shot. Since I don't know if it was the Lupron or the surgery that helped my original pain, it is hard to decide whether or not I'm willing to risk stopping it. The lack of a sex drive is causing serious strain on my relationship, and the other side effects are driving me absolutely crazy but not crazy enough to go back to the way I felt before. If anyone has found things that help the side effects, please email me. Good luck. F 24 4 months
1X M
5/22/2012
Email
 4  Fibroids Insomnia, night sweats I made the mistake of reading the reviews on this site right after I had my first shot and was scared to death of the possible side effects. But the only problem I've had is sleeping through the night. I waver between hot and cold all night and wake up every couple of hours. Other than that, I'm fine. No hot flashes, no mood swings, no weight gain. I exercise regularly and watch what I eat normally, so it hasn't been a problem. Even better, I do believe the medication shrunk my fibroids a little. Enough so that my doctor can remove them laparoscopically in a couple of weeks. Although I love not having a period, I am looking forward to the medication wearing off so I can get a good night's sleep. F 39 2 months
1X M
5/3/2012
Email
 3  Severe endometriosis, fibroids Weight gain (12 pounds in 6 weeks), achy bones and joints, headaches, forgetfulness, lower abdominal/back cramping (sporadic)...Thankful that my menses stopped, but not sure if it was worth the payoff. F 38 6 weeks
4/13/2012

 4  Severe endometriosis Mild hot flashes, weight loss, increase in sweating. Not bad at all for how much of my pain was reduced. Also, started injections immediately following laparascopy to remove some adhesions F 27 6 months
3.75
3/26/2012
Email
 2  to shrink fibroids I have taken Lupron for 4 uterine fibroids. But two of them have grown and the other two only decreased minimally. The effect after the first shot, was very heavy menses for 2 weeks plus with many tissues along with extreme tiredness. For the remaining treatment, i had continued fatigue, hot flashes throughout the day, depression and had to limit my walking. I know everyone has different reactions but i hope this information may help someone else. F 45 3 months
1X M
3/16/2012

 1  Ovarian cysts Extreme headaches, period started right after injection and continued for 10 days, had to have blood tests to make sure I wasnt anemic, no energy, no sex drive,clear discharge, nights sweats,loss of thoughts, insomnia, weight gain, achy bones, irritablility,spotting frequent, cycle still started again after 6 weeks (3 month shot). I also have found the I am getting colds often and it seems like my immune system is somehow compromised while using this drug. There were many cons and not enought pros to recommend this drug. The reason I was given Lupron was because I had suffered with Papladema and pseudo tumor cérebre in the past. I was afraid to take birth control because of that and to find that it can contribute to this ailment is alarming to me. I was supposed to get another injection last week and was sick so I didn't, thank goodness. I was dreading going through another ordeal with this drug. I am scheduling the hysterectomy. F 48 6 months
1X O
3/15/2012
Email
 5  Fibroids Hot flashes, especially intense at night. I, too, heard/read horror stories about Lupron but this was my last attempt at dealing with painful fibroids. I have a great MD who had great expereinces with Lupron, but still encouraged me to do research about the medication. I knew weight gain was a side effect, so I continued my running and was very careful with what I ate. I have to say I am very pleased with Lupron. The hot flashes are miserable, especially at night, but it beats the pain I was in prior to the protocal. I haven't had any issues with mood swings or loss of bone density, but I've always had dairy everyday and I take a calcium supplement as well. I can't say enough good things about Lupron. F 45 6 months
3.75 1X M
3/2/2012
Email
 1  endometriosis This drug has ruined the last 3 months of my life. Numerous ER trips.Hospital stay. Lightheadedness.unable to sit up.stand. numb head hands. Tachycardia constantly.unstable blood pressure. Insomnia.Severe mood swings. Quality of life gone. And I am a mom of 2 boys. F 34 3 months
11.25
2/28/2012
Email
 2  stage 3 endo Night sweats,trouble remembering things,low sex drive,hormonal F 21 3 months
2/20/2012
Email
 3  Endemetriosis in bowel. Hot flushes, memory loss, weight gain, headaches, numbness in my fingers and toes, anxiety and difficulty concentrating. I had a hysterectomy two years ago and have endo in my bowel. As an alternative to a resection I opted to take Lucrin/Lupron to see if removing my ovary would stop the pain. It seems to have settled the pain a bit but the sweats are really uncomfortable. F 44 3 months
3.75 1X M
2/16/2012
Email
 1  Endometriosis Caused campomelic dysplasia of my first baby (it was fatal), I have severe degenerative disc disease, anti MAG neuropathy, malignant melanoma twice, kidney stones, migraines, heart arrhythmia, This drug has ruined my life. I took this drug almost 9 years ago, I was a healthy normal individual before this. It killed my first baby, and then within a span of five years I've had 4 spinal surgeries, my spine is now almost 2/3 metal rods and screws. I've had malignant melanoma twice 12 months apart, I have an auto immune related neuropathy that leaves me in excruciating pain, I get kidney stones on a regular basis and have had to have multiple surgeries, I've developed a heart arrhythmia, frequent migraines, and Luoron never took the endo away for me, I had a hysterectomy at 31. I'm now 36 and on permanent disability. It's like winning the power ball of medical problems, and all of it started after Lupron, just because you feel good now, doesn't mean you're going to stay that way, run far far away from this poison, the truth is going to come out! F 36 6 months
1X M
2/11/2012
Email
 1  inoperable endometriosis I had hot flashes, night sweats, fatigue, dizziness, and ended up with SEVERE pappilledema that caused me to briefly go blind and I needed a VP Shunt inserted into my brain/body because the pappilledema came from the Pseudotumor Cerebri that the Lupron caused. After 3 injections I had to stop any further 'treatment' with lupron and fight to save my vision. I will now need a new VP shunt at LEAST every 10 years for the rest of my life and am now at risk for blood clots in my brain, brain infections, seizures, and blindness if the shunt fails before I have time to have it replaced. I was told it was SAFE and that I should take it for an entire year. F 25 3 months
3.75 mgt 1X M
2/11/2012
Email
 5  Endometreosis Hot flashes, painful sex, exhaustion, no period, bone loss. Side effects lasted for two years after stopping the medication. This medication was a lot to deal with but helped a great deal. The hot flashes were not very hard to handle. The worst part was painful sex. I had painful sex before I started taking it anyway so it was worth it. After the two years of side effects wore off sex was enjoyable again and I was pain free. I noticed discoloration in my teeth though from the bone loss. A tooth whitener helped a little. It was an expensive drug. If I could go back and make the choice over again, I would still choose to take it. F 29 6 months
Unknown 1X M
2/10/2012
Email
 5  Stage 4 Endo diagnosed after 25 yrs None. It saved my life. I was in and out of the emergency room for the pain, inoperable. As long as I take out I can life a normal life. When I stop the pain returns with my first cycle. F 50 10 years
375
2/10/2012

 4  Endometriosis Hot flushes, mood swings, loss of bone density, weight gain. With the HRT and calcium treatments side effects have been controlled. But worth it as greatly reduced the Endo pains. F 30 4 years
Monthly
2/10/2012

 3  Endometriosis I've been off of it for 2 years and I still have hot flashes and no sex drive!!! But It has reduced the rate at which the endo was growing. But if I had to do it all over again, I wouldn't. F 22 6 months
1 x month
2/10/2012
Email
 1  to shrink fibroid before surgery As we all can see, this medication affects everyone differently. Just be prepared for the negative as well as the positive. The lupron cause me so much pain i had to be hospitalized for 4 days. the pain was worst than my labor pain. It came like clockwork every 2 hrs while i was in the hospital. It traumatized me so bad that i ended up not getting the last dose nor the surgery. Again my body reaction was most likely the exception F 40 60 days
1X M
2/10/2012
Email
 1  for endometriosis 40 lbs of weight gain, shut down immune system, pars-planitis in both eyes,severe mood swings, hated everyone/thing, 'out-of-body" experiences; to the point I didnt know who I was, and I'm sure theres plenty more but this is off the top of my head! I was only 17 while i was on lupron and i had to quit my sport in high school and be homebound the remainder of high school!! Throughout the whole 13 months I still had a cycle every single day and the endometriosis actually grew back while i was on it!!I call it the drug of satan! :/ F 19 13 months
1X M
2/10/2012
Email
 1  Endometrosis Bloating, major exacerbation of endometrosis symptoms, suicidal thoughts, weight gain I was worried about Lupron affecting my migraines; this didn't happen, but within 48 hours of the first (and only) shot, my endo symptoms went from bad to insane. I ended up in the ER and had to take morphine for 3 weeks until the pain subsided. I also gained 12lbs of water weight in 6 days and had suicidal thoughts (solely due to the Lupron) I know a few people had had success with Lupron, but I don't think it's worth the risk. F 32 1 months
1X M
2/10/2012
Email
 1  Severe endometriosis. Hot flashes SEVERE mood swings night sweats memory loss weight gain Lupron did not ease my endometriosis symptoms I ended up requiring a hysterectomy. If I could have done it all over again I would have NEVER taken this drug my side effects were too severe. F 31 9 months
1X M
2/10/2012
Email
 1  Endometriosis&Cronic bleeding cysts Hair loss 20 lb weight gain acne vaginal discomfort/loss of sex drive extreme mood swings memory loss extreme pouring sweat hot flashes chills tremors hives angio edema immune system dysfunction immune system disorder developing into possible lupus. depression to the point of feeling like a zombie, very much felt I was not the same person. Periods never stopped Constant bleeding Anemia never went away Cysts continued (proof of cysts by ultra sounds, and CT scans) Swelling in the face, as if I had been on steroids, looked like a squirrel with food stuffed in its cheeks. Ulcers in stomach and mouth Horrible Joint Pain & swelling Major flare in IBS No change in pain, if anything it worsened. Add back therapy of Danazol, made an increase in all the side effects. Long history of failed treatments for endometriosis, chronic large bleeding cysts. Regularly passing out with pain, after 10+ attempts of different birth control pills Lupron was the next option. I was 18, was only explained that it would cause hot flashes - my failure was trusting the doctor blindly and not researching the drug. I was 18 years old. Began injections, being use to pain, the shot was not a problem, right in the hip area like most injections I've never had a problem with but this... I'd vomit, and be over come with radiating heat every time. The nurse would have alcohol prep pads ready for me to smell every time to help control the vomiting. After a year+ of only worsening symptoms, and damaged relationships due to the side effects, I gave up and said stop. I am left with Joint pain & swelling So far no boney changes (so thankful for taking calcium), chronic urticaria (fancy way of saying chronic Hives), thinned hair on my head, increased eyebrow, leg, arm and under arm hair, and a auto immune disorder, yet to be diagnosised. Doctors can only tell that my immune system changed, from weak to over active, to the point of needing an epi-pen for random bouts of Anaphylaxis. It has been 4 years since I stopped lupron. 3 surgeries later and a drug called Lybrel 28, my endometriosis is slowing considerably, and cyst have become rarely present. I do not know where to turn for the immune system problems, there is no family history, or environmental cause but the Lupr F 24 1 years
1X M
2/10/2012
Email
 1  endometriosis Short term memory probs, menopause symptoms, hip & bone pain, depression, cognitive impairment, thinning of hair, tachycardia (fast heart rate) with premature beats in upper & lower ventricles, already had degenerative disk disease but much worse now. It never helped my endo. Hysterectomy in 2003 did not cure it, now I have pain from scar tissue & nerve damage. F 42 6 months
3.75 mg
2/10/2012
Email
 1  endometriosis Fibromyalgia HELL! F 29 6 months
1x
2/10/2012

 1  PCOS Almost four years after only having one injection I am still suffering. Diagnosed with cervical focal and general Dystonia. Dysphonia. Intense bone pain migraines PCOS is worse. Bruise easily. Severe weight gain (63lbs in 11wks) pituitary issues thyroid and adrenal gland issues. Kidney and liver problems. Blurred vision. Extremely weakened immune system. Difficulty sleeping. Hard time processing whole grain carbs. Inability to lose weight. I can lose 30 lbs and in one weekend put back on 20 regardless of eating clean and working extensively with a trainer. Aside from the weight I'm healthy. Blood sugar is normal cholesterol normal blood pressure on low end of normal. I do have blood pressure spikes where it can go from 112/66 to 170/100 in a blink and then drop just as easily as it spiked. The docs still can't figure that out. F 33 1 days
3.75
2/10/2012
Email
 1  Endometriosis extreme weight gain, migraines, bone/joint/muscle pain, memory loss, extreme moodiness, insomnia I would never go on this drug again. Its dangerous and now not only do I have pelvic pain from endo but I also have many other health issues since the lupron. Ive spent a ridiculous amount of money on doctors and majority of them dont even believe whats going on and dont know what to do. F 23 6 months
1X M
2/10/2012

 1  endometreosis I still had alot of pain, severe hot flashes, moodswings, weightgain, and joint paint. I am now 25 and still have all these symptoms and still no period 4 years later. I am tired, sore, cranky moody not, like myself. My doctor still can't explain why my cycle never returned. Bigest mistake F 21 3 months
1/31/2012
Email
 4  endometriosis, cervical polyp extremely mild warm flashes after treatment my polyp was gone, years of menstrual cramps subsided with return of regular cycle F 43 6 months
1X M
1/8/2012

 3  Endometriosis I have been taking Lupron for six months now for severe endometriosis, and while it has improved my condition it has also caused a lot of adverse effects such as, weight gain, really bad swelling in my hands,joints, and ankles. The first few months were really bad about causing hot flashes,mood swings, and fluid retention. I started taking an anti depressant medication to help with these and they have improved.. Overall I think I will be discontinuing it and going back to oral contraceptives.. This is not a good drug to use for a long period of time because it will cause bone loss.. F 29 6 months
3.75 1X M
1/5/2012
Email
 4  Endometriosis Headaches, Hot Flashes, night sweats, weight gain I took the last shot of my 6 month treatment (1 shot/mo) of Lupron in November. I read a LOT of horror stories online prior to taking the drug, but decided that personally, I needed to try it because the benefits could have out weighed the side effects. For me, that was a smart decision. I was in such severe pain. I was on continuous birth control, I had surgery, I took narcotic pain meds, I had cystoscopies and was on the IC diet for months. To say the least, I had investigated other options. I will not down-play the side effects. They are not pleasant. But compared to what I was living with, they are a walk in the park. If you are having mild discomfort and pain from endo, or other issues, think twice before taking this drug. The side effects will probably seem horrific if that is the case. But for me, I will take all those side effects and an extra 30 lbs over the pain and disruption endo was causing in my life. It may be short lived now that the shots are over, but I would do it again if needed and if it will mean keeping all of my organs necessary to conceive. The add-back therapy is a must to keep the worst of the side effects at bay. My doctor was thorough in explaining my choices, and I made an informed one. I suggest you do the same for your own situation. F 28 6 months
1X M
12/30/2011
Email
 4  endometriosis I only started getting hot flashes when I stopped taking the progesterone I was given as it constantly made me spot. I will take the hot flashes over the hell my endometriosis puts me through every month! I have noticed short term memory loss and an extremely decreased libido. I did experience a very emotional state for about 2 days following my first dose. Overall I am pleased with the results as I used to go through such agony due to my endometriosis. This is the first drug that has given me some relief and so far the side effects are totally livable! F 32 4 months
1X M
12/30/2011
Email
 5  Endometriosis Hot flushes rather have them than the pain of endo only problem I had was as soon as treatment stopped endo came back F 20 6 months
12/27/2011
Email
 3  Endometriosis Severe hot flashes and night sweats, memory problems, minor rashes. F 48 6 months
12/25/2011

 4  severe endemetriosis Nausea, hot flashes, weight gain, headaches F 36 6 days
injection
12/17/2011

 2  Severe Endometriosis Severe pain thru whole treatment(pain made 10x worse) lower back pain, numbing of left leg, headachs, hot flashes, mood swings, mild weight gain. Still deciding whether to finish 6 mo treatment plan?? F 22 2 months
12/8/2011

 4  grade III endometriosis night sweats, hot flashes, mood disturbance (increased irritability, depression), memory problems, weight gain F 31 180 days
1X M
12/7/2011

 5  Heavy periods due to fibroids I get got flashes,mood swings,body aches more on the joints.blurred vision here and ther,memory loss and mild depression F 46 2 months
22.5
12/2/2011
Email
 1  Prostate cancer Joint pain and stiffness, numbness in the hands, loss of memory, loss of libido I have refused to take this drug ever again M 64 4 months
? 1X O
11/28/2011

 5  Shrink fibroid before partial hyst Very minor hot flashes experienced and I am in week 6 post injection. I actually feel better than I have felt in months and my bloating is substantially decreased so far so good. It's stopped my severe bloating, even noticable weight loss. Feeling much better and waiting to see if it actually shrunk the fibroid pre-surgery! F 43 3 months
1X D
11/22/2011
Email
 1  Endometriosis Insomnia, constant urination, hypersensitive back and neck muscles, headaches, mental fatigue, bloating Some days I could barely hold my head up. I was up every hour or two to urinate. That, on top of the hot flashes kept me up for practically two months straight. The drug is supposed to last for 30 days in your system. It took FIVE months for me to have a period. F 46 2 months
1 shot 1X M
11/22/2011
Email
 2  endometriosis I experienced ALL the side effects I guess this is not for everyone...I have severe endo..it worked 2 1/2 mos..and now my period returns!! Not too much has changed...I wish all this was over!! I have 2 dogs, ok with being childless (not), but I accept it..I can't work, had to leave school...it really just made things worse, because now I feel like I am having periods and menopause all at the same time!! F 35 5 months
1X O
11/20/2011
Email
 1  Uterine Fibroids Mood Swings, hot flashes, dizziness, blurred vision If I would have known not only the side effects but also that it would not help shrink my fibroids (I went from having two to four total and the one is bigger than before) I would have never got the shot. I have had moderate hot flashes and most of the time upon standing and sometimes after I have been up for a while get a little dizzy. I have also experienced numbness in my arms at times. The worst experience for me is the mood swings. I will be fine one moment and can be crying my eyes out the next. Unfortunately (along with a few other reasons) the mood swings became too much for my boyfriend to handle (and yes he has said that) and he broke up with me, so you can just imagine how that has affected my moods and emotional stability. If I HAD ANY IDEA that all this would come from getting the shot(s) I WOULD NOT have ever got them!! The only thing I look forward to is that in less than a month the second shot should be wore off and hopefully the side effects disappear... F 36 6 months
1X O
11/20/2011
Email
 4  Endo I am experiencing hot flashes, acne, weightgain, vaginal dryness, mild palpitations, forgetfulness, tiredness, iritablity, insomina, a lil depression, spotting, and loss of libido. If you have severe endo like me this is my second go around I took a drug similar to this in March 2006 for 6 months because I only had a 30% chance of getting pregnant... well it worked and I was pregnant by Dec of 2007. Now I have a healthy lil 3 year old who me and my husband are crazy about! I say the side effects are worth it if you are trying to have a baby. But since then the pain returned about 3 months ago so I am now on Lupron. The first month I had a awful headache after the 1st injection. the 2nd month I had spotting. But no side effects until the 3rd month I got the injection my doctor asked if I had any side effects I said no. The very next day I experienced all of the above. Tomorrow is my 4th injection can't wait for these 6 months to be over. So far I have gained about 6 pounds I am 34 and these hot flashes are the pits but the pain from endo and the constant bleeding is worse. I am just praying for the best. Hope this helps ladies take care. F 34 6 months
30 MG 1X M
11/15/2011
Email
 5  Endometriosis-Severe I took it for 6 months, Side effects included Hot flashes 10-15 lb weight gain, muscle/joint aches, fatigue, foggy thinking and memory loss, thinning hair, insomnia, severe bloating, Depression/Anxiety and fluid retension I had all the side effects and I feel horrible about the weight gain, I am going back to school so I can't blame it all on the Lupron but at least 10 lbs of it is due to that related mostly to fluid retention. The other weight I gained was semi related to it from increased appetite related to stress from the side effects and school. I had a laparascopic procedure done in March 2011 and the doctor said it was a mess in there my ovary was wrapped around my ureter in scar tissue and it was all over my colon, I have adhesions everywhere from endometriosis and I have never had any previous surgery. My ovary now is finally not tender and back to normal size! So my story is a complete success, the Lupron did it's job! The horrible side effects are somewhat still present and i have not had a period yet and my last dose was September 7, 2011. So technically I have been off of it from October 7th so about 5 weeks. I am starting to feel a little better and my energy is slowly starting to creep back in. I hope to be able to get back into my exercise routine soon. I was afraid to exercise on it because of the muscle and joint aches and weakness and I was way too busy. F 30 6 months
11.5 1X M
11/13/2011
Email
 1  Fibroids Severe hot flashes and night sweats. Crippling pain in joints, especially the right arm and shoulder. Lots of swelling, headache, confusion and mood swings. I don't think medication should be on the market for women. There has to be a better alternative! F 50 3 months
1X M
11/11/2011

 2  Endo Hot Flashes, Night Sweats, Insomina, Depression, Migranes, Mood Swings, Anxiety Attacks My pain associated with the endo is gone but now I feel like I am going crazy. I dont know if it is worth it anymore. I will be going to the doctors soon to see what my next step should be. F 23 2 months
1X M
11/9/2011
Email
 4  Fibroids I've been blessed, the only side effect I have had in the two months I've been receiving injections was/is I will get a flash of itchiness that comes and goes randomly. F 43
1X M
10/25/2011
Email
 4  Endometriosis, Constant Cramping Hot flashes, night sweats, forgetfullness, mood swings, anger, depression, acne. I am currently on Lupron after having my Laparoscopy in the end of June. The lap did not help as much as they thought it would, I was still bed-ridden with pain. The Lupron has helped to ease the majority of the pain, my biggest qualms with it are the mood swings and forgetfulness. My worst mood swings were generally right after my shot. I notice that I tend to get angry far quicker than before and my patience is short, but now that I am aware of it I try to keep it in check. The depression is difficult to deal with because my fiance is deploying next month. Though the side effects are unpleasant I have not been in tremendous pain like I was before. I did extensive research before taking Lupron and I reccomend that everyone do that (with any medication). The reason I started the lupron is because I want to have kids and did not opt for the hysterectomy. F 21 3 months
1X M
10/23/2011
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 1  Pain with intercourse/ endometriosi SEVERE DEPRESSION, night sweats, hot flashes, neck pain I work in an OB/GYN office. I had been diagnosed with endometriosis causing my pain with intercourse three years ago. I was taking continuous OCP's and the pain was tolerable. Then the pain level statrted to increase. I was considering a hysterectomy, and my doctor convinced me to try Lupron. At first I thought it was a gift from God. ALL my pain was gone I felt great. Never so happy in my life, for about a month. Then over the next month I started to feel more and more depressed. I got my thrid shot and had a complete breakdown mentally. I almost ended up in the hospital.Severe episode of anger outburst threatened to kill my boyfriend, kill myself.... followed by a two hour crying spell. If my boyfriend hadnt been here I dont know what would have happened. I have NEVER had any other episodes of depression or anger issues prior to this medication. My PCP took me out of work and I am currently on Estrogen repalcement to try and counteract the effects of the lack of estrogen caused by the Lupron to see if I can bring my mood back to normal. I am feeling a little better. I will not be having any more injections, I am only hoping that after this month it will be mostly out of my system and my estrgen levels will return to normal. I am also having very severe neck pain and after reading some other posts on here now believe that is also from the Lupron as well. Be very careful if you decided to use this treatment. If you start to have symtoms of depression make your Doctor aware a F 36 3 months
3.75 1X M
10/12/2011
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 1  Endometriosis Mood swings, depression, anger, hot flashes, vaginal dryness, urinary incontinence, breasts got smaller,insomnia, and weight gain. Now years later but in my early 30's-a coccyx that is so weak it dislocates, arthritis, degenerative disc disease, chronic pain in shoulder and back F 34 4 months
injection 1X M
10/3/2011
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 5  endometriosis when taking the progestin, I only got hot flashes during the night, occasional headaches, and horrible mood swings. The irritablity was hard to bear for me and everyone around me. I talked to my doctor we decided hot flashes are better than irritablity. So, I stoped with the progestin and just let Lupron do it's thing. I got hot flashes a lot... but really, it's bearable. Annoying, but bearable. It makes it hard to sleep a whole night through, so I'm tired during the day. All in all, the positive effects of Lupron DEFINITELY outweigh the negaive. I give my stamp of approval and encouragment to try it out. I got the 3 month injection 2x's. Overall good experience with inconviences along the way. No big deal. M 31 6 months
11.25 1X O
9/25/2011
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 1  Fibroids,extremely painful periods Depression, memory loss, mood swings, night sweats, hot flashes, continued painful heavy periods, hair thinning, itching, pain in muscles and joints, headache, nausea/vomiting, bloating, fatigue, hopeless, confusion, paranoia and more. Those around me became very concerned and noticed an extreme change in my personality. What works for one person may not work for another and this drug did not work for me. I still had breakthrough bleeding, pain and suffering. Please do your research and be sure that your doctor is sensitive to your individual case. F 34
3 month 1X O
9/20/2011

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