LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  endometriosis No major side effects, some constipation, gained 5 lbs, period after 2 weeks but my doctor said that will be the last one I will have throughout the course of therapy. F 44 20 days
injection 1X M
6/29/2011
 4  endometriosis migraine, short term memory loss, fatigue, bleeding I've been taking this for endo, don't know if it's helping because I've never shown symptoms(dr found it during oophorectomy for endometrioma). it has given me migraines which a goodys powder relieves in minutes. the memory loss lessened after each month(1 week to a couple days) and a week after each shot I would have a period lasting about 6 days-even though I'm on continuous birth control. I was given the shot to help with long term bleeding anyway, so 1 week versus 1 year of bleeding I can deal with! stopping it now and attempting for pregnancy, if not preggo on my own in 3 months doc is going to start clomid. F 33 4 months
3.75 1X M
6/23/2011
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 5  Stage IV Endo No side Effects Heading into week 3 after my first shot and I feel great. No side effects at all. I would recommend this treatment to anyone, don't be scared. Not everyone has bad side effects. The risk of the side effects were well worth it for me to be able to attempt to have a family. F 31 6 months
3.75 1X M
6/22/2011
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 4  Endo/Ovarian Cysts Very tired the first couple of days after the shot. Felt Great! after that (so far). My face just broke out yesterday, day 7. No bleeding at all but I've had a hysterectomy. Some nausea. I had a hysterectomy 2 years ago & was still having 2-3 day periods (they left my cervix) and HORRIBLE PAINFUL cysts forming on my ovaries. Cried every month curled up in fetal position & couldn't sleep or get any relief. So far, this shot has helped. I feel pretty good most of the time. Every once in a while get nauseated for no reason. My headaches have actually improved. I have always had migraines - increased after hysterectomy - my head feels better on a daily basis than it has in years. Dr has also put me on HRT but I haven't started it yet. So far, so good. F 38 1 weeks
11.25 1X O
6/17/2011
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 5  Suspected adenomyosis Increase in symptoms for the first two months; minor hot flashes throughout; increase in LDL (bad) cholesterol; decrease in HDL (good) cholesterol Lupron has been a God-send for me! After a diagnostic laparoscopy that showed no evidence of endometriosis (huge surprise for me and my surgeon), my doctor and I were grasping at straws for an explanation for my debilitating, constant pelvic pain. Not resolved by continuous BCPs, only slightly reduced by NSAIDs, Vicodin, etc., we both finally landed on the possibility of adenomyosis in spite of the fact that I have never been pregnant. I started Lupron in February 2011, and while the first two months were horrible (I was forewarned), month three gave me pain relief for the first time in years. No heavy "bogginess" in my lower abdomen, no cramping, no feeling like someone was grabbing my insides, twisting them, and trying to pull them out of my body. And if there had been any doubt in my mind that it was working, I was a week late on my fourth shot, and the misery was back. That's the only drawback to Lupron for adenomyosis from my experience - symptoms return as soon as you stop taking it. Lesson learned - don't get the shot late! I know many people have horror stories from Lupron, but it has returned me to the person I was in college before everything started. F 30 4 months
3.75 mg 1X M
6/9/2011
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 5  PC that went to my pelvis bone all the mentioned side effects. had Prostrate surgery....in 92....went free of PC for 12 yrs came back slowly rising to 17........over 4 yrs. Took lupron 7 months PSA then dropped to .04.....went into remission.....went 18 months no treatment....came back up to 17 then i started again...after 4 months its 2.0.........IT WORKS !!!!! our plan is to use lupron to put it in remission, when PSA rises to 17 again start lupron.....my doc says he knows men that have done this for 18 yrs. I believe their are docs out there that way over treat for the fees.....YES, i do . Especially if you have good insurance. Sounds like some of the men on here have been subject to that...iam no doc but all those different treatments when your PSA is in normal range sounds fishy to me.i wouldnt do it.we have to be informed and question these docs. M 73
1X day
6/5/2011
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 5  Endometriosis Hot flashes I was taking Lupron for 5 months due to endometriosis. I got my last shot one month ago and so far I feel as good as on the Lupron. So, during 5 months of treatment I was taking multivitamins (once a day/daily) plus calcium, magnesium, omega3 (3 times a day/ daily). I do not know which one of those helped but I NEVER had any side effects except hot flashes. Note, depression runs in our family. F 35 5 times
30 mg 1X M
5/25/2011
 4  ENDOMETRIOSIS I had one of the worst periods I have ever had 3 weeks after the first injection. I have actually lost 10 lb since the first shot. It is definitely helping me. Before I had so much pain it was a constant issue. Now I feel much better and am way more sexual active since it hardly hurts anymore. I did have the joint pains in the first month, but I think it was worth it so far. F 35 3 months
1X M
5/25/2011
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 3  Endometriosis Weight gain (10 lbs), headaches, fatigue, loss of sexual desire, mood swings, memory loss This is my first time having to do this. I had my last shot June 2011 and it's been about a month now and no period yet. They said normal would be 2-6 months after I would start. I took Northendrone with it and finished that last week. I now have headaches and just not wanting to do much. I hope it was well worth it cause I do not want to do it again. F 27 6 months
1X M
5/12/2011
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 3  Endometriosis Hot flashes, Severe Headaches, Neck Pain, Hair Loss, Memory Loss It reduced the size/eliminated my cyst caused from my endometriosis. However, I don't know if it was worth it considering the side effects. I do know I want kids, which is why I wanted to try this option. Every day my neck cracks multiple times just from turning my head. It brings me to turns. It feels like my brain it swelling in my skull and pounding. The headaches are so severe that my doctor had to prescribe me codeine pills, which hardly keep the pain away. If I'm about to do something, I can forget within seconds of my thoughts. Within the first few months, I lost CHUNKS of hair. HORRIBLE medicine!!! F 25 6 months
30 MG 1X M
4/28/2011
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 3  IVF headaches, bloating/weight gain, moody/cranky, get upset/sad easy /not in control of my emotions which is the worst for me because i am a very relaxed non moody person otherwise, feeling down/unhappy/unmotivated, mild pain/itching at the injection site. used for IVF cycles. the side effects where not so bad once combined with the pill, but once off, wow, i because really moody and down which i dislikes severely as i am not used to being like that. F 38 14 days
10ml 1X day
4/28/2011
 3  Heavy Bleeding/Sleeping Lots Slept 6 hours during the day on day 2. Really unknown about satisfaction since so new. Bleeding is tiny compared to normal. I slept the second day and wondering if anyone else has had this happened? I also started lightly bleeding. I am wondering what is to come. In the past I have slept 3 days a month before my period F 43 3 days
3.75 1X M
4/28/2011
 4  Large Tumor and Endo very very bad depression, hair loss, no sleep at all, cant remember a thing I just had my last injection 23rd of March and im still not feeling right yet I have all the pains of a period without the period, I cant remember a thing, the last 4 months feel like a blurr, Im now on medication for depression, I keep thinking that im going mad and get very annoyed with myself, the memory loss is the worst side effect and i really hope that it goes back 2 normal, I have also been doing some strange things that I would never have done and I feel if i could run away from myself I would, When will I return back to myself again and feel like me ??? F 29 4 months
1X M
4/27/2011
Email
 4  endometriosis hot flashes, night sweats, moodiness, headaches, fatigue, insomnia, some nausea and shortness of breath i have had 3 injections and have 3 more to go. i feel that this is definitely something not to go into lightly, but i feel for me there was no other choice. despite all the side effects i'm hoping the end result will be worth it. i recently had one of my ovaries removed due to an extremely large cyst. the endometriosis also spread to my spleen. they are hoping the lupron clears up the spleen and puts the endometriosis into remission so it doesn't spread to the remaining ovary. i feel for those of you who don't have an informative physician, but my doctor and her nurse are just wonderful. they have been very helpful through this whole ordeal. really an ordeal, i just simply went in for my annual in january and then less than a month later was in having surgery. after being scanned and tested and for so many things i feel like this is just something i have to deal with for a short amount of time that will hopefully get me what i want in the end, something i want more than anything in the world, to have children. i am willing to suffer through this to get that point. F 26 6 months
1X M
4/26/2011
Email
 4  Fibroids Being menopaused at 32 is quite something ! Hot flashes, night sweats began 2 weeks after the shot. Had mood swings but very PMS like. Had a really heavy period 3 weeks after the shot. Had the 3 months dose 1 month before a myomectomy. I've had the shot 2 months ago and I have a month more to go before it fades away. Don't know if the myomectomy helped (3 weeks ago) but hot flashes and night sweats are almost gone. My surgeon told me it helped shrink my huge fibroids and made the surgery easier for her so I guess it was worth it. I was terrified of this thing after I read all those negative comments but I have to say, everything went well for me. For those who had bad side effects, I feel for you and really hope it gets better soon. F 32
11.25mg 1X O
4/17/2011
 5  Fibroids Breast tenderness. Have had no side effects so far from Lupron. F 36 10 days
3.75 1X M
4/14/2011
 4  Endometriosis Depression, weight gain, mood swings, fatigue I had very bad endometriosis and my doctor suggested Lupron. I had a shot once every three months. My cramping and painful intercourse has gone away! I am on feedback therapy to reduce the side effects. I went on anti-depressent b/c I became depressed.I also started taking more calcium supplements. I have felt a lot better since going on Lupron. My biggest complaint is the 20 lb weight gain. I exercise and eat healthy. It was very frustrating to gain all this weight and not be able to lose it! Has anyone noticed that they are getting more grey hair? F 30 1 years
4X O
4/14/2011
Email
 1  Endometriosis Weight Gain, Severe Depression, Mood Swings, Headaches, Crying Spells, Memory loss This is the second time I have tried Lupron in 14 years and I could not complete the six months the first time and it is even worse this time. Suicidal thoughts and mood swings that may have ruined my relationship. There has got to be a better treatment. F 36 1 months
1X M
4/10/2011
Email
 4  Endometriosis Nothing noticable yet. I got my first injection 9 days ago and I have not yet had any noticable side effects. I was so scared to start this medication because of all the reviews I read, but I will try anything at this point to be able to sustain a pregnancy. I don't know if it's normal to not have side effects yet and if they will get worse as time goes on, but as of now, I have nothing negative to report. I would love to hear the timeline of side effects if anyone would like to share with me. F 29 6 months
3.75 1X M
4/9/2011
Email
 3  fibroids In my second week...I have experienced depression, cold flashes, forgetfulness, bloated stomach and now stomach pains. Can't wait till surgery in 3 months and I hope my symptoms get better. My advice is to force yourself to workout as much as you can to keep fat off and release depression. Also, educate the people you love and work for about Lupron so they understand your mood swings. F 46
1X day
4/8/2011

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