LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Endometriosis I have been taking Lupron for six months now for severe endometriosis, and while it has improved my condition it has also caused a lot of adverse effects such as, weight gain, really bad swelling in my hands,joints, and ankles. The first few months were really bad about causing hot flashes,mood swings, and fluid retention. I started taking an anti depressant medication to help with these and they have improved.. Overall I think I will be discontinuing it and going back to oral contraceptives.. This is not a good drug to use for a long period of time because it will cause bone loss.. F 29 6 months
3.75 1X M
1/5/2012
Email
 4  Endometriosis Headaches, Hot Flashes, night sweats, weight gain I took the last shot of my 6 month treatment (1 shot/mo) of Lupron in November. I read a LOT of horror stories online prior to taking the drug, but decided that personally, I needed to try it because the benefits could have out weighed the side effects. For me, that was a smart decision. I was in such severe pain. I was on continuous birth control, I had surgery, I took narcotic pain meds, I had cystoscopies and was on the IC diet for months. To say the least, I had investigated other options. I will not down-play the side effects. They are not pleasant. But compared to what I was living with, they are a walk in the park. If you are having mild discomfort and pain from endo, or other issues, think twice before taking this drug. The side effects will probably seem horrific if that is the case. But for me, I will take all those side effects and an extra 30 lbs over the pain and disruption endo was causing in my life. It may be short lived now that the shots are over, but I would do it again if needed and if it will mean keeping all of my organs necessary to conceive. The add-back therapy is a must to keep the worst of the side effects at bay. My doctor was thorough in explaining my choices, and I made an informed one. I suggest you do the same for your own situation. F 28 6 months
1X M
12/30/2011
Email
 4  endometriosis I only started getting hot flashes when I stopped taking the progesterone I was given as it constantly made me spot. I will take the hot flashes over the hell my endometriosis puts me through every month! I have noticed short term memory loss and an extremely decreased libido. I did experience a very emotional state for about 2 days following my first dose. Overall I am pleased with the results as I used to go through such agony due to my endometriosis. This is the first drug that has given me some relief and so far the side effects are totally livable! F 32 4 months
1X M
12/30/2011
Email
 5  Endometriosis Hot flushes rather have them than the pain of endo only problem I had was as soon as treatment stopped endo came back F 20 6 months
12/27/2011
 3  Endometriosis Severe hot flashes and night sweats, memory problems, minor rashes. F 48 6 months
12/25/2011
 4  severe endemetriosis Nausea, hot flashes, weight gain, headaches F 36 6 days
injection
12/17/2011
 2  Severe Endometriosis Severe pain thru whole treatment(pain made 10x worse) lower back pain, numbing of left leg, headachs, hot flashes, mood swings, mild weight gain. Still deciding whether to finish 6 mo treatment plan?? F 22 2 months
12/8/2011
 4  grade III endometriosis night sweats, hot flashes, mood disturbance (increased irritability, depression), memory problems, weight gain F 31 180 days
1X M
12/7/2011
 5  Heavy periods due to fibroids I get got flashes,mood swings,body aches more on the joints.blurred vision here and ther,memory loss and mild depression F 46 2 months
22.5
12/2/2011
Email
 1  Prostate cancer Joint pain and stiffness, numbness in the hands, loss of memory, loss of libido I have refused to take this drug ever again M 64 4 months
? 1X O
11/28/2011
 5  Shrink fibroid before partial hyst Very minor hot flashes experienced and I am in week 6 post injection. I actually feel better than I have felt in months and my bloating is substantially decreased so far so good. It's stopped my severe bloating, even noticable weight loss. Feeling much better and waiting to see if it actually shrunk the fibroid pre-surgery! F 43 3 months
1X day
11/22/2011
Email
 1  Endometriosis Insomnia, constant urination, hypersensitive back and neck muscles, headaches, mental fatigue, bloating Some days I could barely hold my head up. I was up every hour or two to urinate. That, on top of the hot flashes kept me up for practically two months straight. The drug is supposed to last for 30 days in your system. It took FIVE months for me to have a period. F 46 2 months
1 shot 1X M
11/22/2011
Email
 2  endometriosis I experienced ALL the side effects I guess this is not for everyone...I have severe endo..it worked 2 1/2 mos..and now my period returns!! Not too much has changed...I wish all this was over!! I have 2 dogs, ok with being childless (not), but I accept it..I can't work, had to leave school...it really just made things worse, because now I feel like I am having periods and menopause all at the same time!! F 35 5 months
1X O
11/20/2011
Email
 1  Uterine Fibroids Mood Swings, hot flashes, dizziness, blurred vision If I would have known not only the side effects but also that it would not help shrink my fibroids (I went from having two to four total and the one is bigger than before) I would have never got the shot. I have had moderate hot flashes and most of the time upon standing and sometimes after I have been up for a while get a little dizzy. I have also experienced numbness in my arms at times. The worst experience for me is the mood swings. I will be fine one moment and can be crying my eyes out the next. Unfortunately (along with a few other reasons) the mood swings became too much for my boyfriend to handle (and yes he has said that) and he broke up with me, so you can just imagine how that has affected my moods and emotional stability. If I HAD ANY IDEA that all this would come from getting the shot(s) I WOULD NOT have ever got them!! The only thing I look forward to is that in less than a month the second shot should be wore off and hopefully the side effects disappear... F 36 6 months
1X O
11/20/2011
Email
 4  Endo I am experiencing hot flashes, acne, weightgain, vaginal dryness, mild palpitations, forgetfulness, tiredness, iritablity, insomina, a lil depression, spotting, and loss of libido. If you have severe endo like me this is my second go around I took a drug similar to this in March 2006 for 6 months because I only had a 30% chance of getting pregnant... well it worked and I was pregnant by Dec of 2007. Now I have a healthy lil 3 year old who me and my husband are crazy about! I say the side effects are worth it if you are trying to have a baby. But since then the pain returned about 3 months ago so I am now on Lupron. The first month I had a awful headache after the 1st injection. the 2nd month I had spotting. But no side effects until the 3rd month I got the injection my doctor asked if I had any side effects I said no. The very next day I experienced all of the above. Tomorrow is my 4th injection can't wait for these 6 months to be over. So far I have gained about 6 pounds I am 34 and these hot flashes are the pits but the pain from endo and the constant bleeding is worse. I am just praying for the best. Hope this helps ladies take care. F 34 6 months
30 MG 1X M
11/15/2011
Email
 5  Endometriosis-Severe I took it for 6 months, Side effects included Hot flashes 10-15 lb weight gain, muscle/joint aches, fatigue, foggy thinking and memory loss, thinning hair, insomnia, severe bloating, Depression/Anxiety and fluid retension I had all the side effects and I feel horrible about the weight gain, I am going back to school so I can't blame it all on the Lupron but at least 10 lbs of it is due to that related mostly to fluid retention. The other weight I gained was semi related to it from increased appetite related to stress from the side effects and school. I had a laparascopic procedure done in March 2011 and the doctor said it was a mess in there my ovary was wrapped around my ureter in scar tissue and it was all over my colon, I have adhesions everywhere from endometriosis and I have never had any previous surgery. My ovary now is finally not tender and back to normal size! So my story is a complete success, the Lupron did it's job! The horrible side effects are somewhat still present and i have not had a period yet and my last dose was September 7, 2011. So technically I have been off of it from October 7th so about 5 weeks. I am starting to feel a little better and my energy is slowly starting to creep back in. I hope to be able to get back into my exercise routine soon. I was afraid to exercise on it because of the muscle and joint aches and weakness and I was way too busy. F 30 6 months
11.5 1X M
11/13/2011
 1  Fibroids Severe hot flashes and night sweats. Crippling pain in joints, especially the right arm and shoulder. Lots of swelling, headache, confusion and mood swings. I don't think medication should be on the market for women. There has to be a better alternative! F 50 3 months
1X M
11/11/2011
 2  Endo Hot Flashes, Night Sweats, Insomina, Depression, Migranes, Mood Swings, Anxiety Attacks My pain associated with the endo is gone but now I feel like I am going crazy. I dont know if it is worth it anymore. I will be going to the doctors soon to see what my next step should be. F 23 2 months
1X M
11/9/2011
Email
 4  Fibroids I've been blessed, the only side effect I have had in the two months I've been receiving injections was/is I will get a flash of itchiness that comes and goes randomly. F 43
1X M
10/25/2011
Email
 4  Endometriosis, Constant Cramping Hot flashes, night sweats, forgetfullness, mood swings, anger, depression, acne. I am currently on Lupron after having my Laparoscopy in the end of June. The lap did not help as much as they thought it would, I was still bed-ridden with pain. The Lupron has helped to ease the majority of the pain, my biggest qualms with it are the mood swings and forgetfulness. My worst mood swings were generally right after my shot. I notice that I tend to get angry far quicker than before and my patience is short, but now that I am aware of it I try to keep it in check. The depression is difficult to deal with because my fiance is deploying next month. Though the side effects are unpleasant I have not been in tremendous pain like I was before. I did extensive research before taking Lupron and I reccomend that everyone do that (with any medication). The reason I started the lupron is because I want to have kids and did not opt for the hysterectomy. F 21 3 months
1X M
10/23/2011
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