LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Endometriosis Unable to eat solid foods without vomiting for the entire time. Had to blend all foods. Horrible medication only and best solution was total hysterectomy F 36 1 years
Injections 1X M
2/5/2024
 3  Shrink fibroids for hysterectomy While on Lupron, I had hot flashes in the evening, months of sleeplessness, bone and joint pain, water retention in my limbs which felt strongest at night, libido loss, weight loss (20 lbs, I've now gained back 10), occasional migraines, horrible depression, paranoia (although I was also B12 deficient, too), forgetfulness, extreme fatigue, brain fog, irritability, overly sensitive nerves, and stomach distress. Once or twice I felt like I was having a stroke or heart attack while I was working and stressed. I also would suddenly wake up in the night sometimes gasping for breath as if I was choking. Lupron shrunk my massive 22cm fibroid down to 10cm enough for my hysterectomy (I kept my ovaries) which is the only good thing. However, 1 year after my 2nd dose of the 11.25 3-month shot, I have hyperparathyroidism (due to bone density loss), and also high RBC, hemoglobin, and hematocrit. I had to take iron before surgery, but Lupron apparently raises hematocrit which increases risk of blood clots. Has anyone else out there experienced any of this? I'm so afraid these things might be irreversible. F 44 6 months
11.25 3mo. 2X O
1/2/2023
Email
 1  Prostate cancer Hot flashes. Mind fog. Dizziness. Fatigue. Hot burning skin. Mood swings. Anemia. This stuff sucks. Will never take it again. M 74 5 months
7.5 mg 1X M
3/20/2022
 1  Precocious puberty I was given this horrible chemotherapy drug as a child to treat precocious puberty. It's only been the past few years that I have connected my health problems to this horrible poison drug. I have constant bone pain, osteoarthritis in all my joints, disc problems, fibromyalgia, chronic fatigue, and brain fog. I feel exhausted and like death all the time. I wish my parents knew that this would ruin my health long term, I would have much rather just gone through puberty earlier than become crippled and ill with these horrible symptoms daily. 21 4 months
1X day
1/5/2022
 1  ER+ breast cancer Migraines, blurred vision, nerve pain, twitching muscles and aches, severe neck and shoulder pain, dizzy, chest pains, shortness of breath, severe hot flashes, tinnitus and hyperacousis, high cholesterol It's been 5 months since my 1 month month shot and still have all these horrible side effects. F 51 1 months
7.5mg 1X M
12/4/2021
 1  Endometriosis Severe anger, mood changes, joint pain, hip and leg pain, headache, hot flushes, weakness, fatigue, severe depression! Don't do it, 45 1 months
11.25 1X day
10/2/2021
Email
 1  Fibroids, heavy bleeding I am taking Lupron pre-hysterectomy. This DID NOT stop my periods as it was supposed to, though they weren't as heavy as they were before Lupron. Every once in a while I'd have a sudden, but brief and manageable onset. I just got my fourth and final shot last weekend, and 4 days ago I started having the worst symptoms ever (just after being informed my surgery would be delayed). I can't even leave my house now for fear of a gross, embarrassing mess. A lifetime of heavy bleeding has rendered me anemic; any effort I have put into fighting it since my diagnosis probably went out the window in the past three days. I am so weakened I have slept almost all day. F 44 4 months
1X M
7/17/2021
 4  PC 0 days
45 mg ever 1X day
7/13/2021
 1  Stage 4 Prostate Cancer Extreme hot flashes and sweats every 3 hours. Extreme pain in intestines. Bone and joint pain. Complete loss of sex drive. Shrunken testicles. I felt like I had a bad virus all of the time. Poison! Even my Oncologist agreed it was poison. I quit taking Lupron and stopped all treatment. I am using diet and supplements with the guidance of a nutritionist. I would rather have nature take its course then go through Lupron treatment. Lupron should be banned! M 70 1 years
11.5 MG 1X O
3/14/2021
Email
 4  Prostate cancer First 9 months few side effect, then body hair loss, muscle weakness, aches from waist down, loss of libido, brain fog, insomnia, fatigue, but PSA dropped from 41 to 0.30, and that's what it was for. Had 5 doses of 8, Hope the symptoms fade when finished the course. M 64 15 months
22.5 5X O
2/15/2021
Email
 1  Prostate cancer Horrible bone pain testicular pain penis pain penis and testicles shrunk dramatically hot flashes neuropathy night sweats night terrors brain fog irritability extreme difficulty and painful urination especially at night barely enough energy to get off the couch I will not be having a second treatment M 70 6 months
45 1X O
1/27/2021
Email
 1  Endometriosis and fibroids Massive bone and joint pain, severe hot flashes, headaches, decreased sex drive, anxiety and severe irritability. The cons outweigh the pros for sure. F 37 1 years
30mg 1X day
1/5/2021
 1  Heavy periods Impaired vision, terrible bone pain all over,heavy sweating,hot flashes,insomnia and headaches I was given (2) three month treatments = 6 months of Lupron in 2008, now in 2020 I'm disabled and suffer daily with horrific bone pain,insomnia,peripheral neuropathy in my legs, severe headaches and I haven't had a sexual relationship since 2010, because I have zero sex drive! My life has been taken away and Lupron is the culprit! F 55 0 months
11.25 MG 2X O
12/25/2020
Email
 1  Prostate cancer surgery Hot flashes always fatigued Was a high level competitive cyclist now can only ride at a low level 2x per week havent been able to even cycle with friends as too slow constant joint pain legs and hands cant sleep more than 2hrs even with meds I wasnt told different dosage shots available never consented but got a 6 month shot and Im in 23 weeks and its worse than ever when wills effects start to go away? I got a supposed 6 month injection but feel worse than ever Depressed as doesnt seem this will wear off The Dr only said night sweats what crap Will I ever be normal again ? After research I find they dont know how this drug is metabolized- how did it ever get thru the FDA? M 73 6 months
45mg 1X O
12/23/2020
 1  prostate cancer bad drug should be baned
30 1X day
12/6/2020
Email
 1  Heavy periods Estrogen dom/brcancer Lupron should be banned and makers should be sued. How can doctors dole this out so easily and freely?! I later found out there were other better options for my conditions. Apparently it's a money maker. Horrible pain whole body - extreme weight gain - mood swings - the list is so long. I immediately felt like. 99 yr old and wished i was dead. I still have inability to move some joints and pain after 3 years is just as bad. Doctors claim it is impossible that Lupron can stay in your system that long, well, they didn't get the shot. I had two shots and my life has never been the same. How are they still able to give this to people?! Every day is miserable. I wish there was something we could do. Nobody believes me. Lupron should be illegal and the company that made it should be sued. F 48 0 days
1/3mo shot 1X O
11/19/2020
Email
 1  Endometriosis Seizures, Hot flashes, night sweats, severe paranoia, psychosis, extreme migraines, vomiting, bone pain I was forced on lupron via the military. I went from a smart athletic happy person to completely disabled. Now everyday I exist waiting to die. F 31 3 months
1X O
11/15/2020
 3  stage 4 Breast Cancer hair thinning (50% so far), painful hand joints in the am, night sweats, jaw pain when I open my mouth, diarrhea every morning, depression. The up side is my tumor markers are back to normal, tumor shrunk and disappeared. I'm only on this drug to induce menopause and save my life. The alternative could bring the cancer back. If this were not the case, I would have stopped taking it already, the reviews I've seen are also horrendous. F 49 4 months
? 1X M
11/7/2020
Email
 1  prostate cancer Where do i start,anxiety,depression,huge around middle, tinnitus, muscle and joint aches, high cholesterol, lethargy so tired,nasal congestion, headaches, changes in taste and smell.shrunken nuts, no sex for 4 years, boobs with lumps in. This stuff can change your life, you will want your old self back. Some men it works without side effects great for them,but it is not a one size fits all drug,as many on here know to their cost. I love life but lupron takes all joy out of it.Yes it lowers psa and hopefully keeps you alive,but i did not expect so many side effects and after being off the stuff for more than 2years i do not think things will get better.It does not seem to me that lupron ever leaves your system,it remains in some way. The bottom line is if you have no choice take it,but take as little as you can to remain who you are and stay alive.This is just my opinion on my experience on lupron, get the full facts for yourself on lupron if you find yourself being told you need it, I hope that you do not. M 74 18 months
11.25 1X O
8/29/2020
 1  IVF Fatigue, exhaustion, depression Had to take for 14 days before IVF cycle and another 14 days after. Hate it. Makes me completely exhausted, cannot function during the day, have to lay down and take naps. Depressed, weepy, no motivation F 38 14 days
0.5mg/day
7/1/2020
  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

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