LUPRON Reviews (LEUPROLIDE ACETATE)Average Rating: 2.7 (853 Ratings)Filter ResultsCompare LUPRON with similar:
Type: Rx Drug
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Results are sorted by Gender males first. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 |
More on LUPRON: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR LUPRON | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 5 | PC that went to my pelvis bone | all the mentioned side effects. | had Prostrate surgery....in 92....went free of PC for 12 yrs came back slowly rising to 17........over 4 yrs. Took lupron 7 months PSA then dropped to .04.....went into remission.....went 18 months no treatment....came back up to 17 then i started again...after 4 months its 2.0.........IT WORKS !!!!! our plan is to use lupron to put it in remission, when PSA rises to 17 again start lupron.....my doc says he knows men that have done this for 18 yrs. I believe their are docs out there that way over treat for the fees.....YES, i do . Especially if you have good insurance. Sounds like some of the men on here have been subject to that...iam no doc but all those different treatments when your PSA is in normal range sounds fishy to me.i wouldnt do it.we have to be informed and question these docs. | M | 73 | 1X day | 6/5/2011 | 5 | endometriosis | when taking the progestin, I only got hot flashes during the night, occasional headaches, and horrible mood swings. The irritablity was hard to bear for me and everyone around me. I talked to my doctor we decided hot flashes are better than irritablity. So, I stoped with the progestin and just let Lupron do it's thing. I got hot flashes a lot... but really, it's bearable. Annoying, but bearable. It makes it hard to sleep a whole night through, so I'm tired during the day. All in all, the positive effects of Lupron DEFINITELY outweigh the negaive. I give my stamp of approval and encouragment to try it out. | I got the 3 month injection 2x's. Overall good experience with inconviences along the way. No big deal. | M | 31 | 6 months 11.25 1X O | 9/25/2011 | 5 | Prostate Cancer | in order of discomfort: sleep disorder, memory loss, fatigue, extended belly, hot flashes, no lipido, did I say memory loss? | After radical and chemo my PSA went from 20 to 83 in 4 months. After my first three month Lupron shot it went to .0001 and stayed there. I am not cured but my life has been extended. Ten accupuncture treatments cured my hot flashes. Pray for a cure for all the prostate cancer survivors! | M | 57 | 3 years | 5/31/2008 | 5 | Endometriosis | Extreme nausea, hot flashes, vaginal dryness and depression; the nausea and hot flashed lessened each week until I received the subsequent injection; | I state that I am very satisfied because I was finally able to have a health child; the drug did perform however, the side effects can be severe; my chronic depressed state subsequent to the monthly injections has not been reversed with any anti-depressant; it has been 12 years and I'm still fighting depression | M | 44 | 6 months | 7/18/2008 | 5 | prostate cancer | Hot flashes,joint pain,weight gain,fatigue | Side affects are better than the alternative , spreading cancer | M | 60 | 6 months | 4/2/2015 | 5 | Prostate | Hot flashes ,joint and muscle pain,loss sleep,short memory loss, anxiety, | Stage 4 cancer controlled by this drug that is why I am satisfied. Not many options for me that might be worse or better. Has kept me from a predictable lifespan sofar | M | 58 | 2 years 4 month | 11/23/2015 | 5 | Stage 4 prostate cancer PSA 60 | Hot flashes in the late evenings | I was diagnosed with stage 4 prostate cancer and the cancer had spread to my lungs and lymph nodes. I took 1 month injection for 2 months then a 4 month injection. After two months, my PSA went from 60 down to 0.4. I remained very active and my energy level never decreased either. I am also juvenile diabetic and Lupron did NOT effect my diabetes. I would highly recommend Lupron. It had very little side effects for me and left NO permanent damage like chemo and radiation do. People need to listen to me. THIS STUFF WORKS!!! | M | 57 | 6 months | 2/1/2016 | 5 | Prostate Cancer | Hot Flashes like you can't believe. Sex life is gone. Joint Pain. No Energy, 5 lbs of bacon slapped onto your lower stomach. Armpit Hair Gone (no biggie). It's a miracle to get 2.5 hours of sleep without waking in a sweat. One episode of double vision for 5 minutes that may or may not be caused by Lupron, who knows? | I had high Gleason scores but non-metastasized cancer. In 3 months my PSA went from 5.7 to .2, so I have to say it works. But the doctors want me on it for at least a year if not longer. My next shot is coming up and I'm in the middle of 9 weeks of radiation. There is no way in hell I will take another shot of this poison beyond the next one. 9 months is plenty of time, I don't think doctors appreciate or care about how devastating this poison is on a human being. If you've got stage 4, I understand, but high Gleasons without mets that respond so quickly, should in my opinion, get treated for a shorter time. Good luck to any that need to be on this. | M | 64 | 6 months 1X O | 5/22/2016 | 5 | prostate cancer, radical prostate | ED, frequent urination, weight gain, joint pain, cellulitis. | M | 81 | 12 years 25MG 1X AN | 6/26/2017 | 5 | Prostate cancer after radiation | Hot flashes, slight decrease of energy, zero libido, slight weight gain, forgetful, | M | 74 | 1 years ? | 3/21/2020 | 4 | Prostate cancer | First 9 months few side effect, then body hair loss, muscle weakness, aches from waist down, loss of libido, brain fog, insomnia, fatigue, but PSA dropped from 41 to 0.30, and that's what it was for. Had 5 doses of 8, Hope the symptoms fade when finished the course. | M | 64 | 15 months 22.5 5X O | 2/15/2021 | 4 | prostate cancer | Little fatigue Hot flashes | M | 65 | 3 months 22.5 | 1/18/2016 | 4 | Prostate Cancer | Most common ones especially joint and muscle pain in shoulders. These symptoms are much worse with 6-month injection than with 3-month | When muscle pain is real bad I can reduce it by forcing myself to relax the muscles and deep, slow breathing. Aerobic exercise helps. Running, fast cycling, and cardio machines at gym. I often don't feel like exercising but force myself to get going and the energy follows. I always feel better during and after exercise. | M | 62 | 300 days 45 1X O | 4/29/2015 | 4 | Prostate cancer Stage 4 | I was taking Lupron in 6 month shots. I had two 6 month shots, and after 1 year, my Doctors & I decided to switch me to 4 month Lupron shots. Before, I really was feeling so bad that I was making arrangements to have a bilateral Orchectomy because of the side effects. Doctor team met and discussed my case. At this time I have been declared cancer free from a Stage 4. Bone scans, CT Scans, and MRIs are clear. At this time I must say I am feeling much better on the 4 month Lupron shots. I still have slight leg muscle and joint aches, but nothing like before. As of my last blood tests, my testosterone level is down to <10. The standards are to have it 20 or below. So, I feel like the Lupron is working fine at this point. My PSA continues to be at a steady <0.010. Had one testosterone flair, one month before I got the 4 month shot. It had climbed to 47, but then dropped to <10 the week before I got the 4 month shot. Doctors were surprised. My doctors are still | M | 69 | 1 years 30mg 1X M | 2/18/2015 | 4 | Prostate Cancer | Hot flashes, fatigue, lack of ambition, joint/muscle pain, no libido or erection. | I had a radical prostatectomy in 1991, external beam radition in 1994, started intermittent androgen deprivation (Lupron 4mo.) in 1999. After each form of treatment my PSA dropped to .00, then gradually rose to 3.0 to 4.0. Now I have a Lupron shot whenever the PSA reaches that level. After a Lupron shot the PSA always drops back to .00, however the time it takes to again reach 3.0 to 4.0 is becoming less and less. Now it reaches that point in just 6 to 8 months. Lupron has worked well for me. I'm still alive! Even with the side effects it's better than the alternative! | M | 72 | 8 years | 8/8/2008 | 4 | Prostate cancer | Fatigue, loss of libido, intense feeling of warmth in extremities | My PSA level was 25 (Gleason scores of 7 and 8) three months ago. A CT scan and MRI showed lymph and bone lesions in the pelvic region. After extensive consultation with my oncologist, he prescribed Lupron to shrink the prostate and shut down testosterone production. The side effects are tolerable, just annoying, and the PSA level has dropped from 25 to 3 in a month. It is also necessary to have a baseline bone scan to monitor calcium loss and other possible chronic issues, which will mandate frequent (perhaps even monthly once the Lupron treatment ceases) blood analysis and inconvenience. After 8 months on Lupron, no further androgen ablation therapy will be used until PSA levels begin to rise again. My oncologists stresses the importance of trying to maintain as normal a life as is possible, with deliberate efforts to exercise and stay active. I no longer have to take ten Ibuprofen tablets a day to relieve the stinging lesion pain enough to sleep at night. My oncologist suggests that, while he sees no additional benefit at the present time, there are other possible treatments, including radiation and chemotherapy, that may be tried if and when the Lupron no longer adequately suppresses testosterone production. I find it quite possible to continue my daily activities with a minimum of inconvenience. I plan to participate in a clinical trial designed to determine if the administration of dutasteride (Avodart)after 8 months will lessen the need for Lupron. | M | 67 | 5 weeks | 4/30/2009 | 4 | Prostate Cancer/surg/rad/ | frequent hot flashes followed by cold flashes. Extreme fatigue, body ache legs and back, depresses or down. Tend to be emotional. Increased appetite -gained 16 pounds.Stomach often feels bloated when empty. Some stomach ache. Short term memory loss mostly since the shots. | I took three shots in 08 three months apart. Last was Oct. My PSA has stayed down to .002 ever since the first shot. Last test last month. I have had prostate surgery, 4 years later 37 radiation shots, but 4 years later it came back. The Lupron has controlled the cancer to this point. I will put up with the side effects for it benefits. I had a knee replacement 90 days ago and that pain is also involved. | M | 72 | 13 months | 5/1/2009 | 4 | Prostate Cancer | Very sleepy and fatigued at different time periods of the day, especially after eating.Weight gain (32 pounds in 34 months), increased appitite, cold & hot flashes,some insomnia, irritable | Upon turning 50 my PSA WAS 53.6 and was diagnosed with stage 3 prostate cancer with a gleason score of 9. I recieved lupron and casodex for 34 months and 10 weeks of external beam radiation (imrt). My PSA went down to 0.02 and stayed there for about 6 to 8 months after the treatment stopped. After that it began to double avery 3 months at first, then after about 18 months it went from 6.4 to 15 in 6 weeks. I am now on both drugs again. Have been on them now for 6 weeks as of 11/16/09 and have not recieved the results of the blood test taken the other day. I am also trying MMS. Would like to find other choises as i am told my cancer is not cureable. | M | 50 | 34 months | 11/19/2009 | 4 | prostate cancer | muscle atrophy, total loss of libido, lethargy, hot flashes, etc, etc | the muscle atrophy has been the biggest problem for me. even after stopping the treatments, i can't build any muscle mass and my libido is still shot. I took five 3-month shots and my PSA went from very high to very low. I had my last shot nearly 9 months ago and while my PSA is still low, I still feel like a middle aged woman (attempt at humor). I walk 3 miles a day to help keep my blood sugar under control and it is still a chore to complete. I am going to ask my oncologist if I can get a testosterone shot or something to help with the muscle atrophy. | M | 61 | 15 months | 1/7/2010 | 4 | Prostate Cancer | hot flashes, chills, joint pain, insomnia, swelling of the ankles,testicle pain, impotence. | I always had a high PSA level since 40 yrs old, 5 biopsies, all but the last negative. My oncologist said I had a lump on my prostate, negative biopsy 12 mo prior. Biopsy showed some Gleason 9 samples, serious cancer. Tests showed that the cancer had not spread. Lupron and 45 radiation treatments recommended. Lupron once every 6 months. 1st shot few side effects until the 5th mo when I had many hot flashes. Lupron did reduce my PSA to zero after 1st shot and still zero after 2nd shot. Testosterone at 17. So lupron doing what it is supposed to do. After the second shot several other side effects began with testicle pain being the worst, a dull ache, and wishing for an orchiectomy. Pain mostly gone after about 3 weeks. With the 2nd shot the Dr prescribed clonidine for hot flashes, which also has a side effect of testicle pain not mentioned by dr. Stopped taking clonidine after 3 days. Lupron also made me feel like I was 80 with joint aches and pain, but I was also doing some manual labor that may have caused some of the aches and pain. I do a 16 mile bike ride once a week, most weeks depending on the weather. I also have chills usually before a hot flash and some swelling of the ankles. No sexual desire anymore, but that was gone due to other medication before lupron. I was told to take 1000 units of calcium with 400 units of vitamin D to counter bone loss. The calcium caused some hard stools, so now I take an over the counter stool softener without a laxative. | M | 80 | 11 months unk 1X O | 12/27/2017 |
LUPRON (LEUPROLIDE ACETATE): Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys). FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)