There are 643 ratings for the drug: PROZAC in the Askapatient database.

The average rating for prozac is 3.4.
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Key to ratings for prozac:
5-Very Satisfied: this medicine cured me or helped me a great deal.
4-Satisfied: this medicine helped.
3-Somewhat Satisfied: this medicine helped somewhat.
2-Not Satisfied: this medicine did not work to my satisfaction.
1-Dissatisfied: I would not recommend taking this medicine.

                    
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Rating   Reason Side Effects Comments Sex Age Time Taken
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 1  anxiety Massive inner restlessness that only xanax could stop. M 52 5 days
5-10 1X D
8/18/2010

 5  depression none Prozac has helped me tremendously. With this drug I was able to think rationally instead of just reacting to people or situations that otherwise would have bothered me and brought me to tears. It has helped me with self confidence, motivation, physical energy and has stabilized my moods. Before Prozac I was oversensitive almost to the point of paranoia, feeling hopeless all the time and suicidal, and self medicating with alcohol. After all these years, I feel Prozac isn't working as well as it used to and my doctor has switched my to Cymbalta. I hope it does as well for me as the Prozac did. F 42 15 years
20 mg 1X D
8/12/2010

 1  Depression. Suicidal thoughts, even more depressed, increased anxiety, fatigue. I do NOT recommend this med. All it did for me was make everything worse a great deal. I was not suicidal before I was on this, after a few weeks of being on it I started self harming and really considered ridding of my own life, these side effects even lingered a while after stopping it. F 18 6 months
1X D
7/25/2010

 3  Depression and anxiety insomnia (which I got over after my brain adjusted to the new chemical) initial restlessness/weight-loss (10 pounds) long-term weight gain of 40 pounds (impossible to lose this; body wants to stay at that weight due to SSRI changes to metabolism) delayed ejaculation throughout After 13 years, I am experiencing the so called 'poop-out' effect. I tried increasing to 40mg but at that dose I feel too drugged out. Have to find a new drug of drug combo now. During my years under the influence of prozac, I was more relaxed and at ease socially. Every day things wouldn't bother me; I didn't feel any ups & downs - everything just felt OK and level. In retrospect that was a problem as I was happy to stay in situations that would normally bother/annoy me such as jobs where I didn't like the people I worked with. I would just be on cruise control and had a didnt-care attitude. So even though I didn't have unpleasant feelings, I felt I did not truly grow as a person with all that I experienced. It was sort of like time that just went by. In retrospect I wish I just dealt with raw life without this chemical barrier and used other means to cope. But it was very easy just taking a pill each morning. Now I'm stuck on these types of drugs for life. M 40 13 years
20 1X D
7/18/2010
Email
 4  Depression I was prescribed Prozac when I became depressed due to another health problem I was having at the time. I started out taking 20mg per day and when it didn't help, the doctor increased it to 40mg. I think it did help, but it's hard to tell because I was much happier once my other health problem was resolved. I think Prozac did help somewhat in getting me through that time. F 19 1 months
40mg 1X D
7/17/2010

 5  OCD, depression, BDD. inesistent sex-drive. i've tried many many med, like Celexa, Wellbutrin, Lamictal, but before or after i had to quit taking them for increased anxiety, anger, mood swings, irritability, lack of response. Prozac, the original one is the only med that works very very well for me, deleting anxiety symptoms and let me to organize my thoughts. i'm on it in combo with Gabapentin, 600 mg three times a day. it's a new life. i'm ready to dance now. M 24 2 weeks
60 mg 1X D
7/7/2010

 5  clinical depression-major F 58
60MG 1X D
7/6/2010

 5  GAD, Obsessiveness, mild depression Increased energy at first, possibly low libido, but after taking a long prozac vacation I believe it is just my mental history regarding sexuality causing the problem. Perfect at 40mg, anxiety at 60mg Last year I tried going up to 60mg (for the obsessiveness and anxiety) but it made things worse, DON'T take a higher dose than you need SSRIs are just as ineffective at too high of doses as they are at too low of doses. that being said, at 40mg (my perfect dose) Prozac calms my obsessions, makes me able to let things go, gives me a more energy to do things I love. I recently tried zoloft (thinking prozac wasn't working, when it ended up just being too high of a dose) and zoloft was awful at even 25mg. I know to each his own, but for me, this is my perfect drug, makes me feel like me, no added effects. F 26 5 years
40mg 1X D
5/14/2010
Email
 2  Anxiety and Depression No side effects (not even sexual). I've been taking Prozac for just over three weeks now. For me, taking Prozac is exactly the same as taking Lexapro - absolutely no side effects but no benefit either. I'm not sure if I've become immune after years of successful treatment with Effexor, or whether Prozac wouldn't have worked for me anyway. I'm off to try clomipramine or imipramine next. If they fail, I'll consider Parnate or Nardil. M 34 3 weeks
20mg 1X D
5/14/2010

 3  severe depression and anxiety Severe nausea, weight loss. I tried this back when it was new, am trying it again after severe stress-induced panic attacks and severe depression. Definitely feeling better but still wake up feeling anxious. Makes me sleepy, so I take it before bed. The weight loss is a bonus for me but the constant nausea is draining. Still not working like I hope but maybe the recent higher dose will kick in. Also kills my libido somewhat but it's hard to gauge because one of my symptoms of depression is compulsive sex. I can still achieve orgasm and it is not muted like on some of the other drugs I've tried over the last 20 years so I am not sure which is the root cause of lowered libido, I'm not depressed so bad, or the Prozac (generic fluoxetine) M 49 4 weeks
40 mg 1X D
5/12/2010

 3  Depression, anxiety Delayed/difficult orgasm, felt jittery at first, tremors. Maintained weight loss following severe depression (positive effect). Once the drug kicked in I felt great. Too good. I eventually crashed, went on this ridiculous drinking binge in which I drove my 7 y/o son around with me while I was drunk. I then had a horrific panic attack after throwing all of my Klonopin away and ended up in the hospital where they raised my dosage from 20 to 30 mg. Once again I began to feel on top of the world, spending money, happy to be alive, etc. My psychiatrist told me to stop taking it and now I am back to my melancholy self. I want to keep taking it even if it did make me manic! I also take Lamictal and Klonopin. F 33 6 months
30 mg 1X D
5/11/2010

 1  Depression/Anxiety Extreme nausea, migraines, fatigue, became even more anxious than I was before taking this medication. F 26 18 days
20mg 1X D
5/8/2010

 1  'fibromyalgia' I wish I had never taken Prozac!!! It actually gave me the symptoms of fibromyalgia: poor exercise tolerance, low energy, flu-like symptoms, feeling sleepy all the time, extreme fatigue plus no sex drive and yawning alot. Then when I decided to come off of it I realized that you can't just quit, you have to wean very carefully and take suppliments to help you handle the symptoms. I wouldn't have been able to make it through the withdrawal symptoms without the book "How To Get Off Prozac Safely" by James Harper. It has been 2 years since I started to wean off and 7 months since I completely quit and I still have withdrawal symptoms. This drug is crap. F 53 7 years
10 mg 1X D
5/6/2010
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 1  insomnia, pmdd Fine at first, then increased anxiety, feeling heart fluttering, restless, even missed work, poor appetite I don't think I do well with the ssri's in general. This was way too stimulating to me. Felt like I was drinking coffee all day. F 38 15 days
10 mg 1X D
4/30/2010
Email
 4  Depression Dry mouth. I use a special dry mouth toothpaste and mouthwash which helps. Sexual side effect: Interferes with ejaculation by delaying ejaculation. For me, this is the worst side effect. Prozac (generic fluoxetine) has tremendously improved the quality of my life and, therefore, those around me. I highly recommend this drug be taken in conjunction with psychotherapy sessions to battle depression. In over 18 years of taking Prozac, this drug has never made me feel suicidal or homicidal. The sensationalist news media has given Prozac a bad rap. After so many years of taking this anti-depressant, I'm wondering if I've built up an immunity to it's beneficial effects? I'm going to ask my psychiatrist, an M.D., if he will consider putting me on Serzone or Wellbutrin which have lesser incidence of sexual side effects. M 58 18 years
60 mg 1X D
4/25/2010
Email
 5  depression, anxiety, anger some dizziness at first, yawning episodes at first, no side effects now This medication has really improved my quality of life, and my relationships with family and friends. I was afraid to take a medication to treat my symptoms, but I am so glad I have Prozac! F 29 2 months
20 mg 1X D
4/21/2010

 2  Depression Metal taste in my mouth, nausea, headache, blood pressure seemed higher I had been on Topamax & really liked it. It lifted my mood but it caused me muscle & jaw pain & another abcessed tooth. Dr changed me to Prozac. I was given the generic form of Prozac. Just after 2 days I had a metal taste in my mouth & everything tasted terrible. I felt like my heart was jumping out of my chest & was so uncomfortable after only a week on this drug. My suicidal thoughts came back stonger than ever after 4 days. I've gone back to the Dr. & he changed me to Remeron. F 50 8 days
20 mg 1X D
4/20/2010
Email
 2  PMDD Insomnia, weight gain, inability to lose weight, craving alcohol, binge drinking. I've had a love/hate relationship with this drug for the past 7 years...can't seem to quit it cause of a few nice things. It does help my moods and makes me better able to deal with life. However, I am having progressively worse and worse insomnia at night, coupled with feeling very sleepy mid-afternoon. I also have put on 10 lbs and am having a VERY hard time losing weight. Metabolism has slowed. Also, alcohol feels amplified wile on this, and I can drink much more with less consequences the next day. More cravings for alcohol. I never used to drink this much..not before going on Prozac. I also feel bloated all the time, but that could be the PMDD. Wish I could go off this drug, but whenever I do, it feels like the depression and anxiety is worse when going off than it was before I ever went on it. I'm a mess. (And I have a feeling people get suicidal from this drug from the weight gain..it's absolutely suffocating.) F 41 7 years
10 1X D
4/19/2010
Email
 5  anxiety insomnia obsessive thoughts increased anxiety first week or two, feel hungry after eating a meal, but I don't give in and eat more...no sexual side effects, no dry mouth First psych med I have taken. Very concerned about possible weight gain so I changed my diet when I started this medicine...eliminated sugar, eliminated white and enriched flour products, increased fresh fruits and veggies, eliminated pork and beef, eating lots of beans, almonds, egg whites, fish, and occl chicken. So far I haven't gained any weight...but still worry about long term weight gain. Feel much better...sleeping better, mood brighter and negative thoughts decreased. F 41 9 weeks
10mg 1X D
3/30/2010

 4  Depression, GAD, Anxiety, PMDD I have taken Zoloft, Lexapro, and Pristiq before my Psychiatrist recommended Prozac. She says it can take several months of trying various medications before one fits. I think this one fits. I take the medication at night along with a Klonopin for sleep. Originally I took the drug during the day and my lunchtime, I was a zombie and ready to go to bed. Taking Prozac at night as helped greatly. My PMDD is completely gone and I have not experienced a panic attack while on Prozac. I hope to hold steady on 10mg, but I understand that the dosage can be increased to as much as 40mg and greater. I work out on my treadmill at least 3 times a week and play Wii Fit when I don't have the energy to work out. I take a Mega Women's Multivitamin marketed my Vitamin World, a B Complex, and 1000mg Vitamin C. I am convinced that the chemical imbalance which causes depression, anxiety, etc, can also be counteracted with traditional vitamins. My advice to anyone stuck in the in antidepressant "trial loop" is don't give up. I know when you’re depressed, you don’t want to get up and do anything….but working out, hitting a bunching back, doing some sit-ups really does help. Do you own research, ask your friends, visit the manufacturers' website, and use medical websites. There is hope, remain confident !!! Prozac works for me. F 27 20 days
10mg 1X D
3/28/2010
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 5  Major Depression Fatigue, minor nausea and headaches early on (at the start and every increase), none since Prozac is the first anti-depressant I tried, so I got really really lucky. I started at 20mg and gradually increased so now I'm at 80 every day. I'm also on Wellbutrin, and I feel great. F 21 3 years
80mg 1X D
3/17/2010
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 5  Depression and racing thoughts This medication treated my depression to a certain degree, but I was put on it for racing thoughts, I couldn't put sentences together or grasp what I was thinking and could only think negative thoughts all the time. I'm lucky that this was a good drug for me, as I've seen the side effects that others go through, I'm very thankful that it worked. F 33 8 years
20mg 1X D
3/12/2010
Email
 3  PMDD I haven't started yet. (I rated it a '3' just to be fair.) I was actually given the generic form of Sarafem--which I found out is just a clever way to market Prozac to women for treatment of PMDD. I have been given a prescription for 10mg which I am to take 2 weeks prior to my menstrual cycle beginning. I recently had a pre-menstrual episode in which I screamed and cried so long, hard and loud that I really felt like I was posessed. Scary. I'm already taking Wellbutrin XL (brand name) daily--300mg. But my GYN. said that this would be safe and to give it a try. I'm a bit nervous about starting. Any women out there have any advice or insight to offer? I'd certainly appreciate it. F 39
1X D
3/3/2010
Email
 3  depression swelling of my joints (ankles , knees , and wrists ) bruising slight rash anxious at times swelling of lips an hour after taking it mild heartburn veins underneath the skin have been more visual sometimes eyes feel like they want to pop out of my skin tendonitis I wish I didn't have the nasty side effects. My mood over the past 32 days has been awesome. I am happy , confident, and smiling at the simple joys of life. I have a really stressful job and the stress has subsided tremendously . I have optimism that I haven't had in 2 years ! It also has helped me with eating. Normally when I am really stressed out I eat and eat and eat. I have not had real binge eating in like a month. I have lost 6 pounds in a month. However, I look like I am seriously ill or have been beaten ! I am going to have to most likely discontinue and try something else. F 34 32 days
10 mg 1X D
3/1/2010
Email
 5  PMS & Depression Dizziness the first 6 months or so. Nothing since. This medication has really helped my symptoms of PMS and depression, but over the years it does not seem to work as well as it once did. My doctor has tried to add other anti-depressant medications, but the side effects were intolerable, so I've learned to deal with the symptoms that Prozac no longer relieves. This seems to be the only medication without major side effects. F 43 18 years
40mg 1X D
2/20/2010

 4  Depression and Anxiety Disorder Trouble sleeping the first couple of weeks. Slow but steady weight gain. Although I have been on Prozac for 20 years and it was wonderful for awhile, it stopped working long ago for depression. My big concern is that my memory has gotten worse over the years and I'm worried it could be caused by the Prozac, so I am very slowly weaning myself off it to see if I notice an improvement.I think the memory issue is more than just the normal age-related decline. Has anyone else noticed a problem with memory while taking Prozac? Please feel free to email me. Feedback would be appreciated. F 55 20 years
20 mg 1X D
2/6/2010
Email
 3  depression/anxiety Extreme Nausea that comes and goes,and when it comes its bad.So far nothing else besides a clarity high. Even though i have been taking it just for 4 days i already feel a sense of clarity.I am hoping in the future when it realy starts to kick in that i dont have any horrible side effects.I have been taking anti-deppresents since i was 8 then i stopped at the age of 19-23 to see how i would do off of it the natural way.Now that I am 23 I realize i did myself a great disservice and that i have been suffering without medication these past few years.Now i am on prozac 20mg.I hope there is hope for me on this medication! F 23 4 days
2/2/2010

 5  generalized anxiety and depression My side effects were not sleeping well and no sex drive. I love the fact that I am happy every day no bad days. The doc put me on wellbutrin to control sex drive...made me to hyper and could not relax. Did not work well for me. For the sleeplessness i have 0.5 adivan but still struggling to stay asleep. F 41 60 days
1/30/2010
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 1  Depression/anxiety made me completely impotent!! just to let you all kno, to help with this side effect, you should try a med called cyproheptadine. i took it and it helped. had to take it for about 2 weeks about 2 to 3 times a day annd it really helped me:) M 22 1 months
1/26/2010

 5  Chronic Depression None This medication has been a life saver! Though the dosage has been increased a few times in 19, almost 20 years, I have been most grateful for this miraculous drug. I started havng depression around age 11 or 12, which for me was 1962 or 1963. I do not take the generic. I have had negative results with generics, especially generic antibiotics. I do not trust generics. I've heard some real sad stories from friends taking generics. I was told the pharmacies "push" generics because they make more profit on them. I want pharmacies ,or any business, to make all the money they can. However, I draw the line on generics. I don't like generic foods or soft drinks either. There is a difference, I can tell you that without being a PhD in chemistry. I do, however, have an MA in American Literature! M 58 19 years
12/27/2009

 4  Depression/Anxiety/Binge Eating Dis 1st time- clammy hands and sweating, 2nd time- dizziness and dull headache daily, buzzing in ears I took Prozac 20mg for 2 years and it worked great! Went off for 1 1/2 years but went back on after a recent break-up and medical problems making me miserable. I lost appetite a little at first, but I've been feeling headachy and dizzy everyday. Hoping it will subside. I just went up from 20-40mg as my depression didn't lift after 2 1/2 weeks on 20. F 28 25 days
12/21/2009
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 5  clinical depression The only side effect I noticed is that it takes me a tad bit longer to orgasm, but I'm talking like a few minutes longer, so definitely no big deal at all! No other side effects! This is the first drug that has actually helped me. I've been on about 7 other antidepressants before this one. I started feeling better about 3 weeks into taking it. I started on 20mg, and I'm now taking 30mg. I have noticed a big difference in how I feel. I get excited about little things now that normally would have meant nothing to me. I enjoy shopping and music again. I'm actually decorating for Christmas which I haven't done in years. I'm nicer to people, especially customers at my job. I feel like I want to be friendly to people. I like to make people happy now. I feel like I like my boyfriend more than usual. Someone at work actually told me, "You look so happy today!" and honestly, no one has ever said that to me before. It's always, "What's wrong?" I'm so so happy my doctor decided to try prozac, I feel like I'm becoming a new person. After about 6 years of being depressed, it's definitely a welcome change. I can't wait to see how much better I feel in the weeks and months to follow. Don't let other reviews scare you, every drug works differently for every person! F 23 1 months
12/14/2009
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 3  Depression Sex drive diminished, Sleeping 10 hours at a time and still not feeling rested, nightmares, craving SUGAR like nothing else, weight was up and down, gave me cravings for DRINKING ALCOHOL and sometimes manic I took this drug on and off for a few years, it didn't seem to do much good and I was at 80mg, so I switched to Celexa, Wellbutrin, Zoloft, Paxil, Effexor and some anti psychotics I can't remember now. I am currently on Cymbalta and it seems to help me more than Prozac or the others ever did. F 31 3 years
12/12/2009

 5  Panic Disorder None Its worked very well for me. My panic attacks have subsided and I haven't experienced any major side effects. Takes about two weeks to kick in, but after that I felt much better. M 29 2 years
12/11/2009

 3  Depression Inability to orgasm or get sexually aroused. Became totally numb physically and emotionally after awhile. It became almost impossible to have feelings at all. Worked great to initially help my depression very fast. Was energizing and pulled me out but long term use produced sexual side effects and some mania. F 37 1.5 years
12/11/2009
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 4  OCD and depression. less sexual interests, drowsiness. it's the best SSRI I ever tried. like each med, it has its side effects... but at the dosage of 60 mg it's a very good weapon against anxiety disorders and depression, expecially for BDD and depersonalization with derealization. maybe to stay well more, you'd try an augmentation... leave out from benzos. M 23 4 months
12/8/2009

 4  depression dry mouth and gas both went away after a few weeks; no side effects since, but now I am wondering whether current significant memory loss is attributable in part to long-term usage. this drug gave me back my life; but after so many years, I worry about long term usage; I worry too that it appears to be a permanent medicine, almost in the manner of insulin -- there must be others who have never been able to get off of it. F 59 20 years
12/8/2009

 2  Anxiery/Depression No side effects but it didn't work M 27 1 years
12/1/2009

 2  Panic disorder, anxiety, PMDD Nervousness, anxiety, chest pain, irritability, dizziness, slight nauseau at first, weakness, dizziness, EXTREMELY reduced libido, restlessness, dry mount, extreme muscle pain. Does it do its job? Yes. I don't have panic attacks and it has helped my premenstrual disorder. But at what cost? I am always nervous and restless. I am irritable and easily angered. My muscles ached for a week straight. I gained 15bs. I am weak. It has changed me in the sense that I just don't care. I don't want to do anything or go anywhere. I can't sit still or concentrate. F 24 2 months
11/30/2009
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 5  Premature ejaculation, IBS I began taking Prozac after research that indicated that it helped perhaps 12x greater than a commonly prescribed premature ejaculation drug. I have to say that it indeed does work for me, providing more control than previously. But not only did it help there, it had two other beneficial side effects: It helped enormously with constipatory irritable bowel syndrome (IBS) that I had suffered from for 20 years. It also has had a beneficial mental health benefit that is subtle but definite. I feel it has mellowed me and permitted me to approach things less rashly, though it takes none of the edge off that is needed sometimes in order to get things done. This has been a wonder drug for me in terms of my IBS - will stay on 10 mg per day indefinitely as it has changed the quality of my life rather remarkably. M 49 2 years
11/28/2009

 4  Anxiety and depression/ADD/insomnia Initial side effects were increased anxiety and insomnia, but those abated within days and an improved mood replaced them. I have gained weight, but I also have hypothyroidism, so not sure what's to blame. I also feel pretty drowsy and foggy sometimes, so added Wellbutrin and that seems to help. Recently, heartburn has become an issue, which I have only experienced in pregancy before. My libido and orgasmic ability are probably a little decreased, but not absent. The most obvious and immediate benefit of taking Prozac for me was the ability to sleep without sleeping pills. I am very sensitive to drugs and had to start taking it like 1 mg at a time. Side effects were short and relief was worth it. I stayed on 10 mg for a while, but needed to raise it to 20 mg at some point. That made me tired. Also, the Prozac did not improve my ability to concentrate, so Wellbutrin was added slowly and the combo seems to keep me pretty functional as a mom of two little kids through a marital separation, possile loss of our home, and financial stress. The side effects are worth the ability to care for my children. F 40 3 years
11/6/2009

 4  pms/exstream anger. feeling sick,yawning episodes,loss of appetite,drowsey. was really worried about taking this after reading reviews.my moods where out of control i needed something to help.All my side affects passed within a couple of weeks.feel like i can cope now,i no longer get wound up by the silliest of things.much joy to my husband and young children,oh and me. F 36 26 days
11/6/2009
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 1  Depression Hospitalized with diagnosis of probable acute heart attack. Interestingly it turned out to be the "panic attack from hell." Hallucinations, nightmares, intense anxiety, fainting. On the first day of taking Prozac the trees seemed prettier. On the second day songs on the radio brought tears to my eyes. Later that day abruptly it felt like someone had hit me across the chest with a baseball bat. I went to the ED who diagnosed me with a probable heart attack and spent then night in the ICU. The next day a lack of cardiac enzymes said: "no heart attack." What happened is this: Prozac and most SSRI's are metabolized by the Cytochrome P-450 liver enzymatic systems. Some people have very inactive systems. This is not a problem (usually) but in the case of Prozac, perhaps I could metabolize 1mg/day where for a normal person they might metabolize 10-20mg. So what happened is that I rapidly built up a toxic level. I found out later that my sister and neice had the same thing happen. In short, if Prozac works for you, great. But if you rapidly get increased anxiety or experience a major anxious response it is likely that you too have a less active Cytochrome P450 system and if so avoid all SSRI's. Try an antidepressant that does not use this system like Remaron, Serzone or Imipramine. M 52 3 days
11/4/2009

 1  Depression, panic attacks 24 hr suicidal thoughts, I had a panic attack that lasted a week. Two years ago when I was 14 i was on prozac to try and help with my depression and panic attacks, but this only lasted about a week.. I had a panic attack for a week straight, nothing helped, and i layed in bed all day feeling like i was going to die. Sleeping helped, but as soon as I woke up, i was back into a panic attack. I had to go to the hospital, and they said for me to stop taking it, and told me about Ativan. It was the worst week of my life and I was ready to die. I am scarred for life. F 14 1 weeks
10/31/2009

 2   None noticed for first few weeks, but developed full-body red and itchy hives after 3.5 weeks and then discontinued I took 20mg for roughly 3.5 weeks without any noticeable changes in mood and no noticeable side effects. I was told it would take about 3 - 4 weeks to kick in and was waiting for that, but developed red and itchy hives all over my body (head to toe!) that lasted a week after discontinuing Prozac. Doctors told me it was not an allergic reaction as those should happen within 24 or 48 hours, but Prozac definitely contributed to it as it only appeared after I started taking it and left when I stopped taking it. No particular withdrawal effects. I would've liked it to work as I had no particularly bad side effects, but unfortunately I could not continue with full body hives! F 18 3.5 weeks
10/26/2009

 2  PMDD / Depression None noticed for first few weeks, but developed full-body red and itchy hives after 3.5 weeks and then discontinued I took 20mg for roughly 3.5 weeks without any noticeable changes in mood and no noticeable side effects. I was told it would take about 3 - 4 weeks to kick in and was waiting for that, but developed red and itchy hives all over my body (head to toe!) that lasted a week after discontinuing Prozac. Doctors told me it was not an allergic reaction as those should happen within 24 or 48 hours, but Prozac definitely contributed to it as it only appeared after I started taking it and left when I stopped taking it. No particular withdrawal effects. I would've liked it to work as I had no particularly bad side effects, but unfortunately I could not continue with full body hives! F 18 3.5 weeks
10/26/2009

 4  Depression, Bipolar II minor abdominal pain, some dizziness which wore off after time,nothing serious or severe that I noted. Worked great for 12 years then stopped working. Be sure to taper off. Follow doctors/pharmacists instructions. Thankfully, there are other antidepressants out there that can work just as well if Prozac doesn't work for you or stops working. Recommended that you get a (CMP,etc) every couple months. F 39 12 years
10/22/2009

 5  Depression/anxiety Slight weight gain (10 lbs or so). Didn't have a sex drive to start with so that didn't change :-) I've been taking Prozac off and on for 13 yrs (50 yr old female). I've tried all the others and keep going back to Prozac. It just WORKS. No side effects for me and doesn't 'make me happy' but it certainly takes away all the sad. Enables me to cope when otherwise I'd be a crying sobbing mess. I used to cry off and on all day every day before Prozac. For no reason I could see. This stuff has enabled me to live my life. For that I'm thankful. F 50 13 years
10/21/2009

 2  Bipolar depression I had minimal side effects, felt a little sickly at first...nothing too bad though. I took it seperately, and also combined with zyprexa. Both times I used it, I had fairly bad results. It made me way too manic, almost to the point of being hostile. And gave me a hair trigger temper. It also made me feel isolated and emotionally distant from life. Plus it wrecked my sleep, and gave me crazy, exhausting dreams. My wife hated what it did to me....and so did I. I really wanted it to work....but you can't win them all I guess lol. M 46 6 months
10/21/2009

 5  Anxiety, PTSD Some drowsiness at first This drug has been great in helping me with my afflictions. I now feel that I can continue my life normally and handle situations that just a year ago would have sent me into a tail-spin for no good reason. I can deal withs lifes little problems and even the big ones without falling to pieces. One thing about this drug, most people either love it or hate it. Good luck. M 43 1 years
10/20/2009

 2  BiPolar Disorder I experienced sleeplessness with this medication. With Bipolar disorder this is not a good side effect. F 30 30 days
10/15/2009
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 4  Depression NO SEX DRIVE- NONE! Loss of appetitie- slight. Taking this drug on & off for almost 10 years. Very beneficial to me & my sanity. Prozac is the ONLY antidepressant that works work me. The only BAD thing about this drug is my NON EXSISTENT sex drive. F 32 10 years
10/8/2009

 5  Depression, anxiety Vivid, surreal dreams for first several months. Very slight drop in libido. Benefits far outweigh any negative side effects! I've been taking this "miracle drug" for about 15 years. Though very resistant at first, due in no small part to the stigma antidepressants carried in the early 90's, within a month I felt like a new person. Gone were the black days when I couldn't get out of bed. Gone was the anxiety, perseveration, paranoia and "feedback loops" that drove my crazy. I felt NORMAL. Little things did not get under my skin. I feel upbeat, productive, confident. This drug saved my life, my well-being, and I plan to stay on it until the day I die. I have only had to increase my dosage once in 15 years. I cannot say enough positive things about this anti-depressant. F 39 15 years
10/2/2009

 1  anxiety and migraines suicidal thoughts, palpatations, intense agitation, disassoiciation. I had a major meltdown and went bananas about 18 days after starting prozac - which is about the time it kicks in. Started with a giant panic attack, - so bad I went to ER - followed by 36 hours of being completly crazy, intense agitation, more panic attacks, rocking back and forth, pacing, disassoication and suicide thoughts along the lines of 'I will simply have to kill myself - this cannot go on'. It was the most terrifying experience of my life, especially the suicide thoughts - yes, I'm an anxious person but generally enjoy my life! It was terribly upsetting for my husband and friends to see me like this. After another visit to ER I was given valium which started calming me down, and I finally stopped the pacing and rocking etc and slept. Took five days to come back to myself. F 40 18 days
9/25/2009
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 5  ocd/anxiety hardly any. The only thing I noticed is takes longer to orgasim. Possible sleep disturbances leading to day time sleepiness but nothing that inhibits my life. This drug changed my life. It eliminated almost all of my symptoms with almost no side effects. I am a little more tired now but I am tired and happy verses tired and depressed. F 33 4 months
9/18/2009
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 1  Depression Feelings of intense anxiety---which also gave rise to wanting to commit suicide by cutting my wrists. I also collapsed one morning in the lounge and my partner had to call the ambulance to take me to hospital, and i had a low blood pressure. The suicidal side effects of Prozac are very dangerous. Doctors are not advising you that this can happen when they prescibe the drug. I have since read the results of a large trial (12,000 people) in the UK, where they found that there were no benefits to Prozac at all. In my opinion this drug is now a major embarrassment to the Drug and Medical profession as they appear to have been duped into believing that it was a cure for depression when now it has been proven not to work at all. F 59 3 years
9/15/2009

 2  Terrible PMS - Anxiety Mania - terrible hallucinations and negativity, feeling more anxious and racy, could not think straight or write a complex sentence, woke up sweating, dry lips, boils (I never get these), itchy skin but no rash Apparently my negative reaction to Prozac is an indication of some level of Bipolar Spectrum Disorder - which I did not know I had. I started at an extremely low dose - 5 mg (.5 of the 10 mg capsules) and had immediate very adverse reactions. Inability to think straight and "seeing things" is definitely bad and I was told to discontinue use - which I was happy to do. High anxiety and racing thoughts-mania or hallucinating is an indication to stop using Prozac. I would not try to continue taking it and wait it out. The negative feelings can lead to doing something dangerous. F 40 2 days
9/6/2009

 3  depression migraines & constipation at first; lack of focus; fatigue; weight gain; insomnia It was a lifesaver at first - my body had been through a ton of stress physically and emotionally, and I "snapped" with increasing frequency. However, over 5 years the weight gain, daytime fatigue and nighttime insomnia started to make my life more difficult (try taking 3 medications that ALL cause weight gain). I tapered off the drug 6 weeks ago and am experiencing visual disturbances (hallucinations - my peripheral vision constantly plays tricks on me), plus I'm just not thirsty, and I feel emotionally like I could fall off a cliff at any moment (ie never sure if a mood is normal or part of the depression returning). I don't like thinking that I could be "hooked" on a drug. F 39 5 years
9/2/2009

 5  Postpartum OCD and depression No side effect at all. This was a lifesaver for me!After taking an ocd medication which did not help, I swiched to Prozac.It took about three months to get better, it was very slow, but I never went back to the complete nightmare I experienced after giving birth.After almost two years all my symptoms gone, the "thoughts" are very rare and dont bother me anymore.For a year or so I took 20 mg, then go down for 10mg, I tried it first, was not good, and after a few months I cold do it, then 5 mg, twice again.Since june I am off and in complete remission.Long journey, but I thought it will never end.And here I am healthy and out of the woods. F 31 1.5 years
8/25/2009

 1  Depression Weight gain, CHRONIC FATIGUE SYNDROME During 12 years on Prozac I went from 140 lbs to 180 lbs, even though my diet did not change. My exercise pattern did, though, because I was exhausted all the time. Diagnosis was chronic fatigue syndrome, and they gave me drugs for it, but I made my own prescription: get off prozac! Withdrawal was nasty, but CFS is 90% gone and my weight is going back down. I take St. John's wort and 5HTP instead now. F 44 12 years
8/25/2009

 5  depression/bipolar first 2 weeks were horrible, I was more suicidal than ever but I stuck it out and I got better and I felt the depression lifting, couldn't have an orgasm if my life depended on it had to stop it for that reason this was a great drug for my depression, if I didn't have a husband with sexual needs I would have stayed on it, it really worked for my suicidal ideation and kept me from killing myself F 31 3 months
8/17/2009

 5  Social anxiety None I took Luvox and Celexa before trying Prozac. This is the first SSRI that I have taken that has not caused extreme fatigue. While they helped with anxiety, Celexa and Luvox made me so tired that I had to nap at least four hours a day to function. Prozac has helped me with my anxiety without causing extreme fatigue. F 22 1.5 years
8/13/2009

 1  
8/12/2009

 3  Depression Sexual dysfunction, lack of appetite, memory problems, all of which resolved after about a month. F 37 10 months
7/31/2009

 5  OCD sleepiness I have been taking Prozac for over 15 years and it controls my OCD very well, which I'm thankful for. I still have some obsessive behaviors, but at least i'm not taking 4 hours showers anymore. I can function normally with a few quirks. I do feel very sleepy during the day, which i can't really attribute to anything else. I have some depression with the OCD, but don't want to change or add medications because I think Prozac is one of the safest drugs in this category. I would definitely recommend it to someone that needs medication. F 38 15 years
7/11/2009
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 5  Depression No side effects that I can recall. I took Prozac for 7 years without any problems at all. Relieved my symptons well. F 50 365 days
7/11/2009

 2  GAD; Dysthymia w/ Asperger's The minor ones were all well and good, but it was the Tardive Dyskinesia and the heightened depression that really got to me. My involuntary movements weren't helped by Valium, which usually helps. I would never take this medication again. However, I've seen it work for people on many occasions, and I would not slam it. It was not the medication for me though. M 16 1 weeks
7/7/2009

 3  Depression/Anxiety/Bipolar After day 2 I took 60 Ativan to try to kill my self. Then went in the hospital for a week. After 4 weeks I feel much better but I sweat my a$$ off doing little things. Also nausea all the time but its only mild. Seems to work pretty good. Hard to keep an erection at times but when you get one you can go for ever. Can be a good thing for the ladies who like jack rabbits but I would hate for a female to be on this and ruin her orgasm. Tried many things and this is the best so far. Klonipin has to be used to control the panic attacks I have because the Prozac alone won't touch it. Good luck. M 26 5 weeks
7/6/2009

 3  Clinical Depression inability to really feel emotions, brain fog, insomnia, sexual side effects I was on up to 60mg of prozac for a period of about two years. This drug helped with my depression, but at the cost of all of my other emotions. I was unable to really feel anything- no pain, no joy. I could tell they were there, but I was disconnected from them, and just felt like a robot more than anything else. Difficulty concentrating and communicating. Lower libido, dryness, and inability to climax. In the end I got off of this drug found something better. F 20 2 years
7/2/2009

 5  severe car wreck/abusive husband None- it has been a life saver for me! Was enduring severe anxiety from wreck and ex who attempted to kill me. It gave my life back to me. On 50 mgs daily. F 42 4 months
6/21/2009
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 4  Depression/Anxiety Around two weeks in my daugher (13) had horrible initial side effects. Moods where all over the place, sleep patterns very off, couldn't sleep, scuicidal thoughts. But after these past life is getting clearer for my daughter. I am feeling hopeful about her future. She is now into week 4. F 13 4 weeks
6/8/2009

 3  Depressed, ADD I am always up and awake now. It helped with my depression. I have had one fight with my mom since I have been on it. We used to get in fights everyday and now I'm able to walk away from the situation without arguement. I started taking 10mg now I take 20mg. The docter would up it cause i still cry a lot but i also take 18mg of concerta and that effects my weight loss majorly and it makes me more shakey so he keeps it the same. F 15 3 months
6/8/2009

 4  Anxiety, Depression, Bulimia Weight Gain, Sort of Floating feeling for the first few days, sensitivity to sugar First of all, this medication takes a long time to enter and exit your system, so it takes awhile to work. It took me a full 3 months. Second, this worked well. My anxiety was greatly reduced and I had no depression. I'm off it now because after a year, it hit me that I gained a lot of weight. It's made me really sugar sensitive. Like, I'll experience sugar crashes and headaches after having sugar (which I craved all the time) As diabetes is in my family, this freaked me out. It did do what it was supposed to, however. F 1 years
5/27/2009

 3  panic disorder mild depression weight gain, inability to climax, I loved that the prozac took away my need to "snap" at my kids, or anyone else for that matter. However, the weight gain is bothering more than the slight depression did and I didn't even realize it was from the Prozac. I've never taken anything like this and my doctor didn't even tell me when I asked her why I was gaining all the weight - fool! Anyway, I did like the way it took the edge off. I was taking 20 mg but am not going to switch to Wellbutin XL as they say that won't promote weight gain. Stay tuned F 44 180 days
5/10/2009

 5  Anxiety, Depression switched from paxil so did not have any side effects, took til 40mg to feel a difference I tried lexapro, paxil, and am satisfied with prozac. anything works WITH therapy. just taking a drug won't help your progression. if you do not like this drug, there is one out there that will help. F 23 4 months
5/5/2009

 2  anxiety feeling faint redness face&neck dizziness fatigue dry mouth constant fuzzy headache muscle& joint pain F 57 38 days
4/27/2009

 4  bad P.M.S depression At first zero side effects. I no longer suffered from P.M.S which was lovely. I now take Yasmin which is great stuff as well. After awhile, with the prozac I felt sort of "blah" and emotionless. F 37 3 years
4/20/2009
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 4  bummed out worked good F 55 6 months
4/12/2009

 5   Insomnia for the first month only. Sexual problems. I've been on it for fifteen years, after a lifetime of chronic depression. Very helpful - it saved my sanity! F 51 15 years
4/6/2009

 5  OCD None I think it is the best!!!! F 71 16 years
3/29/2009

 4  Anxiety/Mild ocd none It has helped me. Been on it for at least five years or longer. Do not try to get off of this medicine without going slowly under the supervision of your doctor or you'll think you are losing it!!! F 50
3/29/2009

 1  mislabeling Where do I begin? initially, giddiness, slight euphoria, weird notions, aversion to nonsense phrases (I'm not joking and I still have that!), constipation along with excruciating upset stomachs, heartburn, insomnia, letting people walk all over me, not seeing the significance of things, short episodes of depression, being too liberal morally, poor judgment and foolish risk-taking, confusion, looking uptight for no apparent reason, weight gain, even more aversion to grossness than was normal for me, short attention span, difficulty touching my toes, insomnia, menstrual cramps, suggestibility, trouble articulating. . . during the last stretch, becoming obsessive-compulsive and depressed; fear of merging cars (when I was a passenger), fire (actually it had started before the last stretch), needles (a fear which I retained for some years after quitting), and maybe some other things; some lactose intolerance; inability to eat fruit and dairy together; implantation bleeding; miscarriage pos This drug messed me up spiritually, mentally, emotionally, physically, socially, etc. Be careful about quitting because you'll be sensitive. Get out of the toxic environment and talk to someone trustworthy if you feel unloved or something. It's normal for your confidence to plummet when you first quit. (Do taper off, though.) I'm tired of having to deal with drug damage. Drugs are not the answer! They are dangerous in the ways I mentioned. Don't ever take them! You're NOT genetically sick! F 29 8 years
3/27/2009

 4  Anxiety/Insomnia I had really bad anxiety and sleeping problems and Prozac helped immediately. I sleep well and can control my worries. My libido is up, but my orgasms are weak and not as strong as they used to be. M 28 2 weeks
3/26/2009

 5  Body Dysmorphic Disorder (BDD) None. If you suffer from BDD, or body dysmorphic disorder, please consider giving Prozac a try, it might change your life for the better! It has decreased my obsessive thoughts and other symptoms significantly. F 22
3/20/2009

 2  Depression and Mood swings Insomnia, but extreme fatigue through the days, bad nausea, extremely bad headaches, thirst, irregular heartrate,bloating, dizzy spells, It did help with my moods, but the side effects were terrible. So i stopped. not something i'd recommend in a hurry. F 29 14 days
3/19/2009

 1  Premenstrual Tension Disorder At first none really, then I started to feel emotionaly numb, I lost intrest in everything, my friends, my career, my life, my family, I felt like a zombie. Bruised easy, periods got longer and heavier, vision got blurry, ears became sensitive, didn't care about anything or anyone. It's not for me! F 33 2 months
3/17/2009

 4  Depression, anxiety, panic attacks Uncontrollable yawning episodes during the first 7 days on the drug (even if not tired). Also drowsiness during first 10 days. These symptoms then disappear. No other side effects except for indigestion sometimes. Have been taking Prozac on and off for 10 years with periods of a few months off. It stops the really bad thoughts from getting out of hand, like a safety net. Makes socialising much easier, doing simple things are no longer a huge effort, controls negative gloomy thoughts and makes sleeping pattern more normal. Effect on depression is stronger than on anxiety. One odd thing: the time it takes to kick in varies a lot. sometimes you feel better after 10 days, other times it can take 4 weeks. Average is about 2 and half weeks before you feel any better. So my advice is give it at least 4 weeks. F 49 10 years
3/12/2009

 3  Anxiety, Depression, Panic attacks I've been taking Prozac for about a month now, and I feel better mood-wise, BUT I stay sleepy a lot, but don't really rest well (if that makes sense). Also, I have gained about 5 lbs. in a month.. :( I'm starting to wonder if there is an anti-depressant out there that helps without the weight gain..? Overall, my mood has improved quite a bit, but the side effects are making me question whether it's worth it or not. F 27 4 weeks
3/10/2009

 2  Asperger Syndrome/ anxiety Life became really dull. Music didn't sound good. I had one panic attack, which I have never had before, they are stupid and I don't want another one. Oh, and loss of appetite I'm giving this a 2 just because I don't want to say I don't recommend it. It just really did not work for me, but i know that it has worked for people that I know. I actually don't even really have anxiety, I was just too hyperactive and this was mistaken for anxiety. F 26 14 days
3/5/2009

 1  GAD insomnia at first, headaches, stiffness in neck and shoulders, weight gain, constipation, blurry vision My Dr. rx'd it for anxiety, palpitations and stress. The first week I couldn't sleep despite being so tired. Started getting daily headaches. Prozac had no impact on my mood and palpitations. After 8 weeks I gained 11 lbs despite eating less and working out everyday. My Dr. took my off and switched me to Buspar and my life changed! No more anxiety or palpitations, lost the weight and then some. Headaches are gone too. I feel great now. I am so over the whole Prozac hype! F 29 2 months
2/28/2009

 3  DEPRESSION AND OCD SLEEPLESSNESS, DREAM CRAZY DREAMS AND EXTREME HOT FLASHES I FEEL LIKE I CRY MORE BUT IN THE SAME TOKEN I ALSO FEEL NUMB,I HAVE THIS DON'T CARE FEELING EXCEPT FOR MY COMPULSIVNESS, I DON'T THINK ITS HELP TO MUCH THERE F 38 6 months
2/26/2009

 4  Depression No side effects - however I did have a seizure when I combined with alcohol. This was the first antidepressant I was prescribed at 16yo. Worked really well up until the point I drunk too much and had a seizure. More my fault than the drugs as the label clearly says to limit alcohol! F 23 1 years
2/17/2009

 1  depression and anxiety the most severe insomnia I ever experienced in my life; lost 10 pounds in a few weeks; left me with 1 month of insomnia; I couldn't get my regular sleep pattern back and after that long of not sleeping I checked myself into a hospital for one week where I was put on remeron and was able to get my sleep back. if you are sensitive to stimulants, STAY AWAY FROM THIS DRUG! F 39 7 days
2/6/2009

 5  depression/dysthymia nothing really it helped me a lot. when I go off of it it sucks, but generally a good feeling! F 16 8 years
2/3/2009

 2  depression, anxiety, ocd slight headache i've been depressed/anxious for most of my life and have been on many drugs. i had a few minor breakdowns over christmas and decided to start taking something again. my doctor chose to give me prozac (20mg) because he said it increases energy and i was feeling very tired and lethargic. anyway, the day i took it i also had a reiki treatment. i felt great for a week. i felt excited for no reason. after one week, i suddenly became emotionally numb. i didn't care about anything. after about two weeks on the drug i had a freakout and became hysterical and had to miss work. i had thoughts about jumping off my balcony. i eventually calmed down, but to that numb state where i didn't feel anything. my friend came over that day and did another reiki treatment on me. i immediately felt better and started acting like my old, silly self. so now i'm wondering if that first initial week was the reiki that made me feel good or the prozac? i'm thinking it was the reiki. anyway, i haven't taken a prozac F 29 2 weeks
1/24/2009

 1  major depression, anxiety Insomnia, hypersomnia, anxiety, mania, diarrhea, pain at base of skull, loss of concentration, mental fatigue, anxiety, I had symptoms of excessive crying every day, negative thoughts, sad mood, emotional overeating, feelings of guilt and worthlessness, envy of everyone around me, oversleeping and taking at least one nap a day, inability to wake up in the morning for about 9 months. I had high hopes for this medicine at first. I was taking 10mg for 10 days and by day 6 and felt great-- I had more energy and ability to focus enough to write papers for school. Whereas my depression made me sleep all the time, I had insomnia for 5 days straight. By day 11, I crashed and the medicine pooped out. I slept so much (most of the time 16 hours on end, missed classes, and slipped into a worst state of depression). The worst thing that can happen to a depressed person is to be given hope one day and have it snatched the next day. Needless to say that after many dose increases--up to 60 mg for 2 1/2 months, I went from being a B+ student pre-depression to flunking out of school. I blame the prozac because I w F 26 2.5 months
1/23/2009

 1  mild depression/anxiety insomnia, mentally numb, delayed motor skills, not feeling like myself Well, sure it works for anxiety, cause it numbs you. My life turned slow motion on this drug, at only 5mg daily. I quit after a few weeks, now I am taking high grade Omega 3 fish oil. Look up user ratings on fish oil at www.revolutionhealth.com. It's working for me and no side effects. I do believe Prozac works for major depression, but not for minor conditions. Examine what fuel you are putting into your body. Omega 3 is largely missing from our Western diet and the brain needs it. Good luck to all! F 39
1/19/2009

 5  General Anxiety, Tension Headaches some trouble sleeping at first, adjusted dose and it went away Have been suffering from GAD for many years. Was on Prozac 10 years ago after divorce, 20 mg daily. Started having some anxiety issues again lately and started on 20 mg daily - wow - way too much this time around. I finally found my perfect dose at only 2.5 mg daily! Keeps my anxiety well controlled and no more daily headaches. I am much more even tempered as well, yet I don't have any side effects like weight gain or insomnia due to the low maintenance dose. Please don't give up to quick, talk to your Dr. You may just need a much small dose if side effects are bad. F 40 4 months
1/18/2009

 5  Panic disorder Complete lack of sex drive. Emotionally numb: no ups, no downs, just an emotional flatline. I honestly think Prozac made it possible for me to stay in an unsatisfying marriage for about a decade longer than I should have. Prozac cured my panic disorder, which started in my early 20's. I went off Prozac after a few years and the panic attacks returned. So, back on the Prozac I went. I went off again a few years later and the panic attacks did not come back, yay. However, I became significantly dysthymic off Prozac. My doc then put me on Wellbutrin, as the negative side effects of Prozac had become intolerable. F 46 15 years
1/17/2009

 4  Mild Depresion Not many side effects. i had some problems sleeping for the first 3-4 weeks but it has improved. I think my libido is little bit lower but its still fine! No other side effects (yet..?:) ) I take 20mg a day. It really helped me with my motivation! im more efficient at work, i clean my house regulary and do house work. I just do things without thinking "oh i cant be bothered" or "i'll do it later". I enjoy talking to people again- im more social now. Some things seem to be less annoying (like commuting to work on London Tube!). i could say im more "stress-proof". My thinking and memmory has IMPROVED! Im happy i have tried it!!! it really helped me!!! F 29 3 months
1/17/2009


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Average rating for drug: 3.4. This page is printer-friendly; use landscape print with background color turned on.
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5-Very Satisfied: this medicine cured me or helped me a great deal.
4-Satisfied: this medicine helped.
3-Somewhat Satisfied: this medicine helped somewhat.
2-Not Satisfied: this medicine did not work to my satisfaction.
1-Dissatisfied: I would not recommend taking this medicine.

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