DEPAKOTE Reviews (DIVALPROEX SODIUM)

Average Rating: 3.0 (584 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on DEPAKOTE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPAKOTECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Mood stablizer Had elevated ammonia levels, toxic, decreased drug & levels came down, stopped rx completely, ammonia levels normal, 2 wks later severe Tardive Dyskinesia started & continues 7 mths now. Desperate for help from this awful drug. How does one find medical help for this??? Depakote has been dangerous with horrible side effects for many years. Drs afraid to stop it. An emergency decision was made to stop this rx after 3 wks in the hospital. Now needing 100% from a caregiver. Awful drug. Awful we cannot find anyone to help us. The pharmaceutical co that makes this should help the patients get the necessary care that their drug caused asap. M 39 15 days
1000mg 2X day
1/2/2023
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 1  Misdiagnosed bipolar Rapid weight gain, puffy appearance, brain fog, memory loss short and long term, decreased libido, zombie like emotions, sleeping too much or too little, muscle weakness, Took this drug on two separate occasions for misdiagnosed bipolar depression and alcoholism. While taking experienced brain fog, memory loss, weight gain etc. First time I stopped cold turkey and had extreme anxiety, panic, suicidal ideation, and for the first time ever extreme rage and homicidal ideation and plans. Second time I knew to taper off but even so, still experienced anxiety, stomach problems, insomnia, muscle weakness, extreme fatigue, sleeping too much, and depression. Avoid this drug please. M 26 2 years
1000 mg 1X day
3/26/2022
 1  bipolar Sleep all day long no energy. Hands trembling and balance issues. Weight Gain. Many falls since on this medication. Do not recommend. F 66 6 months
750mg 1X day
7/20/2021
 1  Bipolar mania with trazodone Awful hair loss feel like I have the flu all the time stomach aches and muscle fatigue I hate drugs I'm not even sure I am bipolar F 53 3 months
1000 mg 1X day
11/16/2020
 1  Bipolar Disorder I'm feeling like sh*t. HORRIBLE abdominal pain in my right psoas muscles. I see a massage therapist and a chiropractor, but they have no idea how to help me at all. I don't really know what's happening with my body? I don't trust the doctors. I'm going to see a new physician this morning. If she doesn't respond to my side effect complaints, I'll be looking for a patients' rights attorney in the afternoon! The side effects didn't hit me as hard when I was younger as they're hitting me now. M 54 36 years
1,250 mg.
11/9/2020
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 1  Incorrectly diagnosed with bipolar Hair loss, 15 kilos weight gain, daily migraines, idiopathic hydrocephalus, tremors, balance issues, memory loss Doctors don't know enough about serious side effects of valproate. Refusal of psychiatrist to acknowledge serious side effects. Subsequently got third professional opinion - severe post traumatic stress disorder. Ended up having to have neurosurgery to insert a shunt to treat hydrocephalus which I believe was either caused or exacerbated by the administration of Valproate. Weaned off Valproate. Extremely dangerous drug if prescribed incorrectly & by incompetent specialist. Prescribed this medication for incorrect diagnosis of bipolar for a patient that has Spina bifida oculta. Taking folic acid does not counteract the side effects of this medication. Have been told by medical professionals that the specialist that prescribed Valproate for me was negligent. Extremely concerned that younger women are not adequately warned of potential & serious birth defects. Please note that Valproate is now banned in some European countries. How much does the pharmaceutical company pay doctors to prescribe this poison? Valproate nearly killed me. Be very careful & get more than 1 independent opinion before taking this poison. F 57 100 days
1000 1X day
9/10/2020
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 1  Treatment for a mental health dx Sedated, sleeping most of the time I was sedated on this medication for weeks while on a trip to rehab. The psychiatrist said it is my body adjusting to it and it takes a few weeks to be fully effective. Unable to wake up like I was in a black out deep sleep for 8+ hours every day. Confused, sleep a lot. When I told my primary dr about this, he told me he never heard of this medication, and I was taken off it. F 30 0 days
1X day
7/30/2020
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 1  Schizophrenia,anxiety,bad thoughts It made me throw up and gave me diarrhea. It gave me moodswings and thoughts of suicide made my chest tight and I also had a mini stroke from taking it After the moodswings and all went away I started getting burning in my brain after taking it it gets really sore too. I have damaged nerves as well I can't take sleeping pills at all depakote messed up parts of my brain and the sleeping meds won't work. F 23 22 days
400
10/21/2019
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 1  Bipolar mood swings and anxiety Hair loss, slowly over months and ended with hardly any of my hair left. Constant stomach pain. Nausea. Migraines. Lethargy, weakness, bone pain. Jaw clenching and neck pain. Permanent tinnitus and some hearing loss. Severe withdrawal syndrome. Brain damage. Depakote is the devil in disguise. Don't take it. When I started it I felt good, but over months I developed more and more side effects. I tried to come of it many times but couldn't due to horrendous withdrawal symptoms. It took me years of gradually reducing it and I'm off it now for nearly a year. I feel permanently damaged by this toxic drug, however I feel so much better off it. It has done permanent damage to my hearing. It also gave me a diagnosis of arthritis which my doctor says has improved so much that he could undiagnose my arthritis. Depakote destroyed my physical health. F 40 10 years
1000mg
8/21/2019
 1  Schizoaffective disorder Inability to concentrate even for a minute, dizziness, lack of motivation, tiredness throughout the whole day, depression, migraines, stomach aches, hand tremors, weird dreams, mood swings, anger issues, body temperature issues, social withdrawral, comprehension issues. Thank God for talk therapy, this drug kills. Was diagnosed with schizoaffective disorder after a flip out because of weed cookies i think and just a whole lot of stress and smoking weed for the first time. Ever since taking this drug ive lost my promotion at work lost all motivation, lost the ability to handle losts M 25 9 months
500mg
7/10/2019
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 1  Bipolar Weight gain Insomnia Skin fell of hands and feet Stomach pains Void of thoughts M 28 0 days
3/13/2018
 1  bipolar 1 hypomania 30 lb weight gain, extreme hand shaking & finger tremors. Caused social anxiety. Two-thirds of thick long hair fell out, & was developing drug-induced parkinsonism. The tardive dyskinesia was far worse than from taking Seroquel. Shrink finally started to reduce dose to 750 mg then 500 mg, after I said the drug isn't even FDA or Health Canada approved for bipolar "maintenance." There are no controlled studies to prove that this drug can actually prevent more manic episodes. It is approved for acute mania & it did get the hypomania under control quickly. Now my shrink wants me to stay on the 500 mg/day, saying that it'll help prevent manic episodes. I was also taking 200 mg/day Seroquel, & my shrink says that most likely caused the 30 lb weight increase, so she is switching it to Latuda. I know it was the Depakote causing the rapid weight gain, because I had been on just Seroquel for years. It also caused weight gain at first, but my weight was steady F 66 11 months
1000 mg 1X day
2/26/2018
 1  For bi polar disorder Nausea loss of appetite acid reflux Sleepiness blurred vision loss of balance Runny nose constantly cold F 46 4 days
1000 mils
12/10/2017
 1  one seizure Brain fog. Lethargic, but feel like I always need to be doing something. Withdrawal from family, friends M 56 24 years
750 1X day
3/18/2017
 1  Schizophrenia It doesn't cure any symptoms.depression persists.sleeping disorder persists.i take it regularly night along dinner.doctor says it is preventive.dont accept this drug for any kind of depression as my liver became fatty induced by this drug.i became inactive and sedative.i feel lethargic throughout.i could not have regular sleeping hours. I am relieved of depression symptoms by a genuine homeopath but I could not get rid of side effects of allopathic medicine.can any one come to my rescue M 52 2 years
500
1/20/2017
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 1  Sectioned. 1000 depokote 400 depot Asleep day and night. Bald patches, sad, scared, no feelings, Zombie. Better of dead, reduce , impossible. Give it to you so they have peace, torture, cruel, your better of muddling throu life. Poison, don't agree to take it, was given when I was section with depot clopxide let me out on a very large dose , and no one cares. I have no friends I just exsist, moved to a new area, so scared. M 42 4 months
500x500
12/28/2016
 1  Sectioned. 1000 depokote 400 depot Asleep day and night. Bald patches, sad, scared, no feelings, Zombie. Better of dead, reduce , impossible. Give it to you so they have peace, torture, cruel, your better of muddling throu life. Poison, don't agree to take it, was given when I was section with depot clopxide let me out on a very large dose , and no one cares. I have no friends I just exsist, moved to a new area, so scared. M 42 4 months
500x500
12/28/2016
 1  Bipolar Hair loss , weight gain, depressed mood , wierd dreams, hungry all the time , miserable feeling towards well being F 21 3 months
1000
12/20/2016
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 1  Bipolar disorder The psychiatrist added depacote to other drugs while I was hospitalized as I was getting overloaded with meds it made me comatose w the combination. The dr. I had didn't know what to do was then sent to a state hospital that detoxes me of everything. Glad I'm alive and refer to depakote as something I'm allergic to so no dr in future puts me on it Scares me F 49 1 days
?
12/16/2016
 1  Stabilize my mood Really bad diarrhea. So weak i can barely stand. Tremors severally in my arms. It spaces me out but I get insomnia from it. Feel a little paranoid also M 49 7 days
500mgs
10/14/2016
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DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

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