DEPAKOTE Reviews (DIVALPROEX SODIUM)

Average Rating: 3.0 (584 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPAKOTE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPAKOTECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Epilepsy None known. I have been taking sodium valporate for over thirty years and have not had any significant side effects. While taking the medication I completed two undergraduate degrees and one graduate degree from a top 10 university. I have my CPA and work for a Fortune 500 software company developing accounting software. I don't suffer any ill effects that I am aware and I don't think the drug has limited me. 48 30 years
3/13/2009
 4  post stroke seizures the only significant side effect i have noticed is a lot of hair loss of my already thin hair. it is like i am shedding when i towel my hair off after my morning shower! It has never been like this before. I am on a 750 mg daily dose and it has apparently kept me seizure free. I like it except for the hair loss. 57 5 days
7/10/2007
 4  Bipolar God send! This medicine makes life so much easier! I'm Better more vibrant of a person to be around! Not anxious, depressed or manic. Slight Weight gain. 29 91 days
1X day
6/14/2021
 4  TBI's Great medication to be on thus far!! I don't want to get too excited as it's only been 7 weeks That I've been on it. But my thoughts can finally calm down, I don't get riled up about everything that's not worth it, or replay unnecessary or have irrational thoughts. I'm much more easy to talk to than I've ever been, carefree, free spirit, This is what semi normal feels like!! Those closest to me have noticed a day/night difference. I haven't felt this relaxed since a kid!! Side effects: constipation, nausea at first, following conversation at times. 0 days
2000 mg 1X day
5/8/2022
 4  Hyper Mania Having spent a lifetime as the 'skinny' guy, I've put on nearly 1.5 stone since starting the drug. Has given me my life back regarding the hypermanic spells though. I can work,think and get on with daily life without bewilderment. 34 6 months
11/8/2005
Email
 3  
4/13/2006
 3  biopolar diarrhea, headache, nausea, sleepiness, unusual drowsing, dizziness, loss of strength and energy 25 4 months
1500 2X day
2/24/2016
 2  Moods I liked this medication at first as it calmed me down. It now after being on Depakote for a year, my apartment is a mess, I'm numb to everything around me, I'm tired all the time + gained a extra 30 lbs = 47 total. that lowered my self esteem. I'm also grieving. However.. I know it's the Depakote it slows down metabolism. I don't recognize myself. Who have I become? Looking to lower/get off after I get off another med. Not worth the side effects. 1 years
1500 1X day
5/5/2023
 2  Mania Depa-nope or depa-doped Will control and calm you down if and, or needed. loss my ability to function normally felt like my brain was frozen.. and I couldn't process information I was reading . Take if needed, or switch to something more tolerable. Hair loss, tired, calmed, less anxious 33 100 days
1500 1X day
5/30/2021
 5  Bipolat I finally feel like I can relax, like the hyper stress I am always under is gone, like I can just hear the silence instead of loud racing thoughts in my head. After all these years, I feel like myself again. Not a ping pong ball going from one crazy extreme to another. It does make me sleepy, but happy sleepy. Not stressed or fatigued sleepy which is what I felt during every low episode. For the first time, I can sit down and focus without fighting a battle to feel focused, I can go out without feeling paranoid like all eyes are on me, I can talk to my husband without feeling like he is out to attack me. This treatment is amazing and it is working for me. I honestly just want to praise God! for the first time ever that I can remember, I can sleep without having nightmares. Rest. I can finally rest. F 32 2 days
1000 mg 1X day
3/7/2021
Email
 5  Mood stabilizer I like this medication. It really works for me. It gives me a boost in energy. Does it do that to anyone else? F 57 1 days
500 1X day
9/18/2022
Email
 5  Bipolar Loss of appetite, mood much more stable ,kept me awake for about a week at nights then went away , causes some confusion,anxiety can be worse at first I take this with fluoxetine F 34 2 years
500 mg
7/21/2015
 5  Bipolar 1 Hand tremors (remedied with Primidone); Memory loss (no remedy); Hair loss (remedied by Bosley for Women). Depakote has been my go-to drug when the lithium just isn't "holding down the fort". Have had to recently restart due to family problems. Depakote is a good drug for mood stabilization, but with side-effects, which really, any drug has. F 53 15 years
1500 1X day
1/5/2015
 5  seizures weight gain, hair loss, i get shaky at times, and possible tooth decay. I have been on Depakote for almost 3 years now. I have not had one single episode since I have been on this drug. It had it's bad side effects at the beginning but my hair is back to normal and I got back to my normal weight or around my normal weight. F 18 3 years
4/7/2009
Email
 5  Bipolar 2 stomach burning like hunger pains, wake up once every night at 2 am, some twitching I think that it saved my life. I have been misdiagnosed for 12 years (was diagnosed as depressive with ADHD). Depakote started working after only a few days. Was scared because I thought that meds would change my personality..... it has, but in a positive way. I am able to process information and concentrate better. My energy level has levelled out. Was afraid that I would be considered boring now, but friends and family are so happy that I am no longer self destructing. My thoughts are no longer crazy and out of control. I have control over my impulses. I don't get obsessed. F 32 30 days
4/15/2009
 5  cyclothymia (mild bipolar disorder) Only on 375 mg/day. Some stomach upset at first (a probiotic was suggested by my doc, which remedied the issue), drowsiness, mild appetite decrease. Nothing major. Have read that most major side effects occur above the 1000mg dosage. So far so good. My biggest complaint is drowsiness, but I am also taking klonopin with it which my psychiatriast says is known to cause drowsiness when taken together. We are attempting to tweak the dosing time to remedy the issue. Otherwise, I am happy with it. This is the first drug that controls my moods without inducing mania (antidepressants do that to me) and it has no effect on my sex drive nor has it caused me to gain weight (everytime I take antidepressants I encounter rapid weight gain and sexual side effects). Absolutely zero weight gain so far. Not every drug is for everyone but this one seems to work for me. F 28 3 months
7/20/2009
 5  bipolar II weight gain, memory loss, depression and anxiety Depakote decreases levels of acetyl l-carnitine which is an amino acid that plays several important roles in the human body; It helps to reduce anxiety, depression, improve weight loss and inhance memory. Acetyl l-carnitin could be found in red meat and dairy. Your body can produce a very small amount of L-Carnitine on a daily basis. But since I'm vegetarian and have been taking depakote for years, guess what? I've been suffering from anxiety disorder and depression for years and was treatmnet resistant. Since I started taking acetyl l-carnitin, my mood has significantly improved and anxiety disappeared. I did research it says people who take anti seasure drugs should take high doses of acetyl l-carnitine. I hope it helps someone. F 24 5 years
7/30/2009
 5  Bipolar Disorder I did have to get over some initial side effects of stomach upset. I felt tired at times in the begining which was actually good. I would rather be calm and a bit tired than freaking out. All I can comment on is how it works for me and for me it's great. F 27 5 years
9/11/2009
 5  bipolar II weight gain, thinning hair, though i'm taking remeron too, so not sure it might me from that one too taking 2000mg. The drug is beautiful, minor side effects, though it doesn't control my mood swings completely, i still can take only 7,5mg of remeron for my depression daily, be on casein/sugar/gluten/caffeine free diet, and control my binges, otherwise it doesn't help much F 24 3 years
10/5/2009
 5  Migraines Tender breasts, some hair loss, some fatigue, but a really content and mellow feeling, which is a great side effect for me. Some minimal weight gain in the first 2 months (2 kgs), but I workout daily and eat very healthy, so it has gone down again. I slept more with the almost daily migraines and its just hair, and I still have enough, so I am definitely not complaining! The only thing is if I forget to take it, I immediately get a headache. Also, I talk a lot more in my sleep and have more vivid dreams, but my hubby calms me down, so I go right back to sleep. But my quality of life is so much better with this medication and its the only medication I take, so maybe that's why it works better on me than most people here. I'm very happy with it! F 46 4 months
500
3/9/2013
  

DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

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