DEPAKOTE Reviews (DIVALPROEX SODIUM)

Average Rating: 3.0 (584 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPAKOTE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPAKOTECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Moods I liked this medication at first as it calmed me down. It now after being on Depakote for a year, my apartment is a mess, I'm numb to everything around me, I'm tired all the time + gained a extra 30 lbs = 47 total. that lowered my self esteem. I'm also grieving. However.. I know it's the Depakote it slows down metabolism. I don't recognize myself. Who have I become? Looking to lower/get off after I get off another med. Not worth the side effects. 1 years
1500 1X day
5/5/2023
 1  Mood stablizer Had elevated ammonia levels, toxic, decreased drug & levels came down, stopped rx completely, ammonia levels normal, 2 wks later severe Tardive Dyskinesia started & continues 7 mths now. Desperate for help from this awful drug. How does one find medical help for this??? Depakote has been dangerous with horrible side effects for many years. Drs afraid to stop it. An emergency decision was made to stop this rx after 3 wks in the hospital. Now needing 100% from a caregiver. Awful drug. Awful we cannot find anyone to help us. The pharmaceutical co that makes this should help the patients get the necessary care that their drug caused asap. M 39 15 days
1000mg 2X day
1/2/2023
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 5  Mood stabilizer I like this medication. It really works for me. It gives me a boost in energy. Does it do that to anyone else? F 57 1 days
500 1X day
9/18/2022
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 4  TBI's Great medication to be on thus far!! I don't want to get too excited as it's only been 7 weeks That I've been on it. But my thoughts can finally calm down, I don't get riled up about everything that's not worth it, or replay unnecessary or have irrational thoughts. I'm much more easy to talk to than I've ever been, carefree, free spirit, This is what semi normal feels like!! Those closest to me have noticed a day/night difference. I haven't felt this relaxed since a kid!! Side effects: constipation, nausea at first, following conversation at times. 0 days
2000 mg 1X day
5/8/2022
 1  Misdiagnosed bipolar Rapid weight gain, puffy appearance, brain fog, memory loss short and long term, decreased libido, zombie like emotions, sleeping too much or too little, muscle weakness, Took this drug on two separate occasions for misdiagnosed bipolar depression and alcoholism. While taking experienced brain fog, memory loss, weight gain etc. First time I stopped cold turkey and had extreme anxiety, panic, suicidal ideation, and for the first time ever extreme rage and homicidal ideation and plans. Second time I knew to taper off but even so, still experienced anxiety, stomach problems, insomnia, muscle weakness, extreme fatigue, sleeping too much, and depression. Avoid this drug please. M 26 2 years
1000 mg 1X day
3/26/2022
 2  bipolar 1 Tremor, excessive and long sleep/stupor, muscle aches, weakness, short-term memory decrease; hypersomnia worsened with additional Latuda Rx; had to stop both, and/or reduce divalproex. Lithium was excellent for 40 yrs. until kidney function reached Stage 3 and allergic reaction emerged to lithium. I am not sure muscle aches are only due to divalproex or a knee injury/fall in Aug. F 70 3 months
750mg 2X day
3/1/2022
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 4  Bipolar type 1 A little bit of indigestion I've only been on depakote for 5 days but I already love it ,,, this is coming from someone who has a horrible fear of medication took me 6 months to work up the courage to take it and I have no regrets besides the fact that I didint try it soon ,, so many negative reviews but I have nothing bad to say about it !!! F 19 5 days
250 mg 1X day
2/17/2022
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 1  bipolar Sleep all day long no energy. Hands trembling and balance issues. Weight Gain. Many falls since on this medication. Do not recommend. F 66 6 months
750mg 1X day
7/20/2021
 4  Bipolar God send! This medicine makes life so much easier! I'm Better more vibrant of a person to be around! Not anxious, depressed or manic. Slight Weight gain. 29 91 days
1X day
6/14/2021
 4  Bi-Polar 11 I gained 35 lbs in six months. Every month I asked psychiatrist to take me off. I understand he was stabilizing me. But I've never lost 35 lbs. it's been 15 years. I didn't have any side effects beside rapid weight gain F 55 6 months
30 1X day
5/31/2021
 2  Mania Depa-nope or depa-doped Will control and calm you down if and, or needed. loss my ability to function normally felt like my brain was frozen.. and I couldn't process information I was reading . Take if needed, or switch to something more tolerable. Hair loss, tired, calmed, less anxious 33 100 days
1500 1X day
5/30/2021
 2  seizures Gait problems, cannot sleep, and speech problems. I had to change from lamicil because of problems and this the third medicine I am trying and I want to try something new. The lamictil did wonders at one time. F 79 14 days
500 2X day
5/24/2021
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 5  Bipolat I finally feel like I can relax, like the hyper stress I am always under is gone, like I can just hear the silence instead of loud racing thoughts in my head. After all these years, I feel like myself again. Not a ping pong ball going from one crazy extreme to another. It does make me sleepy, but happy sleepy. Not stressed or fatigued sleepy which is what I felt during every low episode. For the first time, I can sit down and focus without fighting a battle to feel focused, I can go out without feeling paranoid like all eyes are on me, I can talk to my husband without feeling like he is out to attack me. This treatment is amazing and it is working for me. I honestly just want to praise God! for the first time ever that I can remember, I can sleep without having nightmares. Rest. I can finally rest. F 32 2 days
1000 mg 1X day
3/7/2021
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 1  Bipolar mania with trazodone Awful hair loss feel like I have the flu all the time stomach aches and muscle fatigue I hate drugs I'm not even sure I am bipolar F 53 3 months
1000 mg 1X day
11/16/2020
 4  Stabilize Mood Swings Works amazing for my mood but I cant sleep and I'm always hungry!! F 26 8 days
750mg a da 2X day
11/12/2020
 1  Bipolar Disorder I'm feeling like sh*t. HORRIBLE abdominal pain in my right psoas muscles. I see a massage therapist and a chiropractor, but they have no idea how to help me at all. I don't really know what's happening with my body? I don't trust the doctors. I'm going to see a new physician this morning. If she doesn't respond to my side effect complaints, I'll be looking for a patients' rights attorney in the afternoon! The side effects didn't hit me as hard when I was younger as they're hitting me now. M 54 36 years
1,250 mg.
11/9/2020
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 2  Juvenile myoclonic epilepsy Had ONE seizure as a teenager because I stupidly took ecstacy one. Whole team of doctors convinced I have epilepsy. Prescribed me this poison of a medication. I gained weight, skin is horrible, I'm moody, it ruins your insides. Birth defects, the wordka. PLEASE read up on ALL the side effects before you take this. Drowsiness really got me. I could sleep for ten hours every night easily. I've finally weened myself off this crap without the doctors help as they think it's a bad idea to go off it. I won't be poisoned anymore sorry Horrendous F 27 10 years
500mg 2X day
10/8/2020
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 1  Incorrectly diagnosed with bipolar Hair loss, 15 kilos weight gain, daily migraines, idiopathic hydrocephalus, tremors, balance issues, memory loss Doctors don't know enough about serious side effects of valproate. Refusal of psychiatrist to acknowledge serious side effects. Subsequently got third professional opinion - severe post traumatic stress disorder. Ended up having to have neurosurgery to insert a shunt to treat hydrocephalus which I believe was either caused or exacerbated by the administration of Valproate. Weaned off Valproate. Extremely dangerous drug if prescribed incorrectly & by incompetent specialist. Prescribed this medication for incorrect diagnosis of bipolar for a patient that has Spina bifida oculta. Taking folic acid does not counteract the side effects of this medication. Have been told by medical professionals that the specialist that prescribed Valproate for me was negligent. Extremely concerned that younger women are not adequately warned of potential & serious birth defects. Please note that Valproate is now banned in some European countries. How much does the pharmaceutical company pay doctors to prescribe this poison? Valproate nearly killed me. Be very careful & get more than 1 independent opinion before taking this poison. F 57 100 days
1000 1X day
9/10/2020
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 1  Treatment for a mental health dx Sedated, sleeping most of the time I was sedated on this medication for weeks while on a trip to rehab. The psychiatrist said it is my body adjusting to it and it takes a few weeks to be fully effective. Unable to wake up like I was in a black out deep sleep for 8+ hours every day. Confused, sleep a lot. When I told my primary dr about this, he told me he never heard of this medication, and I was taken off it. F 30 0 days
1X day
7/30/2020
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 2  Anxiety, moods Very very sleepy, seem like I could never get fully awake. Headaches, heartburn! I took the gen test and this was one that was a go! Due being so sleepy was only on for 5 days I had to discontinue this meds on day two of stopping meds no withdrawal thank God, still over sleepy today. F 31 6 days
500mg
1/14/2020
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DEPAKOTE  (DIVALPROEX SODIUM):  This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.   FDA Approval Date: 1983-03-10 (Sources: U.S. Centers for Medicare Services, FDA)

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