ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  cystic acne I started getting mild stomach issues towards the last 2 days of taking accutane. i stopped it immediately but it was too late. The permanent damage its caused to my body ruined my life forever. A few months after I stopped accutane, my digestive issues got 100x worse and I developed new conditions. I have since been diagnosed with inflammatory bowel disease, autonomic dysfunction, POTS, peripheral neuropathy, and degenerative disc and joint disease. I am disabled now. Several years later and I am still disabled, getting worse every year. and this was from a LOW dose. This stuff is pure poison. This will ruin your life and all the serious effects happen after you stop F 27 3 months
20mg 1X day
6/24/2022
 1  Nodule acne I have struggled with weird skin issues for years. Dermatologists always prescribed topical meds and nothing worked. I have itchy inflamed knots under my skin. Mostly on my face and some on my neck. They never fully go away except when I took steroids for another skin rash condition caused by allergy to another med. my new dermatologist put me on Accutane confident it would cure. 7 months nothing. I had horrible skin, new eczema developed, depression, horrible peeling lips, and I started feeling lethargic. She wanted me to keep taking it 10 months but I don't have insurance and it was so costly. I had to quit. I felt it was doing more bad than good. Now I've been off it a month and my health is declining. I got a bad yeast infection, vomiting, lethargic, dizziness, massive weight loss, trouble eating, and my skin is even worse on my face now. DO NOT PUT THIS TOXIN IN YOUR BODY Would love to know if anyone else has similar health issues now. What has helped? I am going to see a functional doctor next. F 38 7 months
1X day
4/15/2022
Email
 1  Folliculitis I used 20mg of accutane for only 10 days before I developed ringing in my ears and quit immediately. Unfortunately it was too late and the damage was already done. 3 years later and I still have daily ringing in my ears, and since then I've developed even more health issues which my primary doctor thinks are caused by the drug. Cracking in my joints, dry eyes, migraines, erectile dysfunction, and floaters in my eyes. All of this from 10 pills. It's hard to believe how destructive and poisonous this drug can truly be. If I took a single more pill, it probably would have killed me. It's pure poison, and clearing the skin is simply a side effect of your entire body getting poisoned. It's ridiculous and concerning that this treatment is considered safe and given to young people. M 29 10 days
20mg 1X day
1/4/2022
Email
 1  Cystic acne I took accutane about 30 years ago (I was in my mid 20's) when it was first introduced / new on the market and back then there were very little warnings for all the possible risks and long term effects. Since taking it, over there decades my health has been a slow but continuous decline in ways that aren't explainable by my genetics. My siblings are all healthy; my parents never had any of the health issues I've suffered from. I felt fine while using accutane. What nobody warned me about is what would happen to my health and body in the aftermath of using this drug. Had I known it was a chemotherapy I would have of course never touched it, but this information wasn't disclosed (intentionally, perhaps?) to me. Who would take this drug for acne (no matter how severe) if you know it's a cytotoxic chemotherapy??? NOBODY… well, only insane people. In the past 30 years I have developed damage to virtually every part of my body. By age 30, I had lost half my hair and couldn't work out normally anymore due to pain and stiffness in my joints. My age 35, I developed seriously dry eyes and some new digestive problems. I struggled with infertility throughout my 30's and was never able to conceive, despite trying many times and seeking fertility assistance. By age 40 I had serious bone pain, arthritis, and MRI showe If you're reading this review thinking of using accutane, keep in mind that after ingesting this poison you will live the rest of your life not knowing how it will possibly ruin your health and body insidiously in the future. PLEASE READ THIS: zero.sci-hub.se/902/294a852b5aa6cb77485c16eeed8d6126/goulden1994.pdf The number of patients reporting either transient or persistent symptoms during the follow-up period was 74 (10-3%). Onset of symptoms ranged from 6 weeks to 10 years after stopping therapy. M 54 4 months
40mg 1X day
1/2/2022
 1  Cystic acne Accutane will ruin your health. It isn't a matter of IF but rather WHEN. I felt more or less fine while using this drug 5 years ago. Blood tests, the usual normal symptoms, dry skin lips hair etc. Things were normal, I was working out, going to school, etc. It wasn't until the following years that my health problems all started. A few months after the course ended, I started losing massive loads of hair and my eyes became dry. They have progressively gotten worse over the years. Then, 3 years later, joint pain- in my elbows and knees at first, but soon after it spread everywhere in my body. Accutane will damage your health in the future, it's not matter of "if", burather "when". M 28 5 months
20mg/day 1X day
1/1/2022
 1  Acne on face and back. Erectile dysfunction and no orgasm. I can ejaculate, but I feel literally 0 orgasm. Loss of libido. Avoid. Try exhausting other methods to clear acne. M 22 1 years
12/1/2021
 1  Polycystic Acne I took Accutane many years ago...13 years ago to be exact and I still suffer from cracking joints, chapped lips, dry scalp, dry skin... the list goes on. The cracking joints are embarrassing as I'm only 34 years old. I've waited years for it to stop and it has not. I'm glad I found this thread. I'm going to try taking vitamin D and see if it helps.... I'm seeing a Dr now to try to get to the bottom of it. On top of all of this....I Still Have Acne F 21 6 months
Don't reme 1X day
3/13/2021
 1  moderate acne After a couple of weeks I felt that something had changed in my head. I went from being confident and happy to feeling extremely anxious and tearful. 2 months after stopping this drug I became psychotic and felt suicidal. I also then realized that I could no longer get an erection. Nobody knew how to help me, my psychiatrist told me that I was just depressed, I knew it was the drug. Six years on and I still suffer with debilitating depression. Nobody warned me of the hideous side effects. This is a chemotherapy drug and is an overdose of vitamin A. It causes permanent brain changes and is causing misery to thousands of young people. It should be banned totally and the victims compensated for having their lives ruined by incompetent dermatologists. M 26 28 days
20 2X day
2/24/2021
 1  mild acne Erectile dysfunction, low libido, depression, anxiety, PTSD suicidal ideation. suicide attempt. permanent joint pain. Loss of muscle man and no longer able to make gains. ruined skin can no longet tan, loss of hair. aged considerably. Isotretinoin destroyed by life and these side effect are not rare. Research before you take it. Go on forums and believe what victims are saying M 31 8 months
60mg 2X day
2/20/2021
Email
 1  minor skin problems every body that takes roaccutane are going to end up with permanent damage arthritis all the joints,you will not be able to move 10 to 20 years after you have taken the drug roaccutane is a chemo drug that has destroyed my body and life.everybody who has taken this drug needs to see a lawyer, roaccutane is a chemo drug that destoys lives,everybody needs to see a lawyer for permanent damage M 49 10 months
40 1X day
12/31/2020
 1  Chronic Cystic Acne Loss of almost all scalp hair, still losing it, loss of eyebrows, lashes and body hair, change of colour, texture, thickness, elasticity of hair before it fell out. Conjunctivitis, permanent eye pain, problems with night vision, dry eyes, back pain, scalp pain, earache, joint pain, cracked bleeding lips, strange ridges in finger and toe nails. TOXIC POISON. My dermatologist repeatedly recommended this to me, as a safe natural vitamin A product which would cure me in a short time, unlike long-term hormones, and the worst I could expect was to feel uncomfortably dry. I asked him 2-3X about any effect on my (beautiful, thick, curly red hair) and he assured me the effect was just temporary dryness and that as soon as I stopped taking Accutane all side effects would cease. Every time I expressed concern he would say to me : "Who's The Doctor??" I agreed to try it. After three months I stopped and that's when the hair loss started. I had never had a problem before and was not on other meds. What all the experts I subsequently consulted called Telogen Effluvium became chronic and never stopped. The doctors all denied it was related to Accutane! They're still prescribing it. Hoffman LaRoche isn't suffering, my dermatologist (now comfortably retired I expect) never suffered, Health Canada who approved it never suffered. They're all responsible for destroying my life and clearly others' but didn't pay even as much of a penalty as someone who steals a loaf of bread to keep from starving. Dr. L. S. in Montreal, I pray every day that YOU in particular rot in hell. If your doctor suggests you take this garbage, ask him/her first if they are willing to pay for your wigs. I'm thinking, no. F 59 90 days
40 mg 1X day
9/26/2020
Email
 1  Acne I was prescribed Clavaris 40 mg at age 57. On day 17 my hearing or ears were ringing so bad I had to stop. My ears still ring all the time after 2 years. I went to a hearing specialist ENT and there is no recourse or going back to undue damage done from this drug. You have to sign a waiver form to get this drug. It is a way to limit or deny lawsuits when you medically fall apart or are damaged by this drug. Tell the doctor NO WAY! Acne will not kill you but this drug will! You are not fighting cancer where you need to take this big a risk. Beware of this drug stay away! This drug has helped some but I feel from my experience to pull it off the market! Ban it! M 57 17 days
40 1X day
9/16/2020
 1  Acne Pain in all joints, tendons in the feet, all up my spine/neck. I cant walk right anymore and im only 18. This drug is terrible even though its cleared my face before this i could do whatever I wanted to but now I cant because of the pain in my joints and all. M 18 7 months
80 2X day
9/14/2020
 1  Severe cystic acne I developed severe cystic acne in my 20s and by the time I was in my early 30s I tried every antibiotic and medication there was. I was put on Accutane for the shortest course of 15 weeks. I developed severe headaches, totally debilitating. I also had the dry skin and eyes. It wasn't until several years later that I started developing the side effects. I lost my eyebrows, hair on my head thinned, my menstrual cycle ceased permanently so I was never able to have children, elevated liver enzymes, degenerative disc disease which has now developed secondary scoliosis that has progressed to the point that I cannot walk or even stand unaided. I developed major depressive disorder with suicidal ideation, generalized anxiety disorder with panic attacks. These conditions have lasted until now and I am 54 years old today. No Accutane cleared my acne for good it also ruined my life. I eventually lost my business and had to go on disability because of the severe back pain from the DDD and emotional problems. Please take this medication with serious forethought. F 54 15 weeks
30 mg 1X day
9/13/2020
Email
 1  Mild acne Terrible hair shedding. Persisted even after accutane. I currently lose 300+ hairs a day and it is thinning by the month. M 18 4 months
40 mg 1X day
7/31/2020
 1  enlarge pore blackheads depression suicide attempts ,dry damage skin that does not heal,arthritis in many joints,knees back spine elbows,life and body destroyed by this drug. do not take roaccutane it is actual a chemo drug that nobody is told about,I was perfectly healthy before i took the drug which has destroyed my mind and body,roaccutane will eventually be banned,but not before it has destroyed everybody who takes it lives,roche i hope you rot in hell you will be held responsible M 49 10 months
20 2X day
2/3/2020
Email
 1  Acne Cracked lips and ends of mouth, dry skin on face, pain on heels, knees, back pain, Rectal bleeding, mild rash on arms. I cannot walk or stand properly due to pain in heels of feets, back and knees. Cannot walk for long time and have pain while passing stool. F 25 4 months
2 tablets
1/5/2020
 1  Acne F 19 100 days
30mg
12/22/2019
 1  Acne I had extremely sore joints. I could not run properly. My hip would partially dislocate. EXTREME depression (like hell on earth). Dry lips and bloody stool the list goes on and on... I took it at 16 foolishly thinking the side effects were temporary. Well I'm 27 today and I pop my back, fingers, and knees about 50 times a day. I can't eat carrots (vitamin a source) or drink ANY alcohol without feeling terrible. I defecate 8 to 10 times a day. I'm 100% sure Accutane caused this. I was extremely healthy before this. absolutely no health problems besides depression before taking Accutane. This stuff is poison. I'm sure my joints will only get worse as I age. I'm laying in bed with aching joints as we speak. I feel like I'm 50 years old not 27. No wonder they took the name brand Accutane off the market. It has destroyed people's lives. 27 6 months
80 mg
12/10/2019
 1  mild/moderate acne DRUG RUINED MY LIFE. SUICIDAL EVERY SINGLE DAY 5 years later. All the tissues of my body have been irreversibly damaged - brain, nerves, muscles, joints, tendons, ligaments, skin, hair, bones. All in severe agonizing 24/7 pain. Feel like I'm burning in hell constantly, was disabled by age 22. My father being a doc sent me to his derm friend, who convinced me that low-dose accutane was 'safer than long term antibiotics'. He said all the stories and press were unfounded in science literature and not linked to accutane. Convinced me to take low dose. Was ok for first 3 months treatment, then developed ache in ankle. He said it wasn't related. Mild hair shedding. Became more depressed. Stopped treatment early, 5 months in. 5 months after I stopped, ENTIRE BODY FELL APART, severe brain damage/borderline brain dead, confused, barely able to walk or stand, pain spread to EVERY SINGLE joint in entire body with horrific cracking, skin ruined, facial fat atrophy, hollow eyes, I look 20 years older and feel 90. Developed parkinson-like tremors, suicidal depression, wished for death, burning nerve pain like I'm soaked in acid. All this happened AFTER I stopped. This is the most horrific coverups in modern medical history, a genocide of youth. I am 100% sure the literature showing 'no link' between IBS, depression, and accutane use is completely fabricated. SO MANY PEOPLE INJURED BY THIS. Even in my normal life I know people damaged by it. Completely disabled have been mostly bedbound for 5 years I am in the process of applying for euthanasia. I cry and am severely suicidal every moment of the day. I had a great life before this and was studying to become a dotor, 4.0 student, athletic, happy. ROCHE, YOU WILL BURN IN HELL. F 27 5 months
20mg 1X day
10/2/2019
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ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

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