ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Acne I was prescribed Clavaris 40 mg at age 57. On day 17 my hearing or ears were ringing so bad I had to stop. My ears still ring all the time after 2 years. I went to a hearing specialist ENT and there is no recourse or going back to undue damage done from this drug. You have to sign a waiver form to get this drug. It is a way to limit or deny lawsuits when you medically fall apart or are damaged by this drug. Tell the doctor NO WAY! Acne will not kill you but this drug will! You are not fighting cancer where you need to take this big a risk. Beware of this drug stay away! This drug has helped some but I feel from my experience to pull it off the market! Ban it! M 57 17 days
40 1X day
9/16/2020
 1  Acne Pain in all joints, tendons in the feet, all up my spine/neck. I cant walk right anymore and im only 18. This drug is terrible even though its cleared my face before this i could do whatever I wanted to but now I cant because of the pain in my joints and all. M 18 7 months
80 2X day
9/14/2020
 1  Severe cystic acne I developed severe cystic acne in my 20s and by the time I was in my early 30s I tried every antibiotic and medication there was. I was put on Accutane for the shortest course of 15 weeks. I developed severe headaches, totally debilitating. I also had the dry skin and eyes. It wasn't until several years later that I started developing the side effects. I lost my eyebrows, hair on my head thinned, my menstrual cycle ceased permanently so I was never able to have children, elevated liver enzymes, degenerative disc disease which has now developed secondary scoliosis that has progressed to the point that I cannot walk or even stand unaided. I developed major depressive disorder with suicidal ideation, generalized anxiety disorder with panic attacks. These conditions have lasted until now and I am 54 years old today. No Accutane cleared my acne for good it also ruined my life. I eventually lost my business and had to go on disability because of the severe back pain from the DDD and emotional problems. Please take this medication with serious forethought. F 54 15 weeks
30 mg 1X day
9/13/2020
Email
 5  for my acne - tired -brain fog -stomach bloat -easily aggitated -nauseous/motion sickness -out of breath -back and joint pain (hips and elbows) - swollen glands -worsened eye sight -skin easily cuts -dry lips and skin month 1 - 20mg month 2 -40mg month 3 -40 mg month 4 -60mg month 5 -60mg month 6 - 70mg month 7 - 70 mg month 8 -70 mg F 22 8 months
70 1X day
8/23/2020
 1  Mild acne Terrible hair shedding. Persisted even after accutane. I currently lose 300+ hairs a day and it is thinning by the month. M 18 4 months
40 mg 1X day
7/31/2020
 5  Cystic Ance Dry lips, fatigue, splits on the side of the mouth, nosebleeds, back pain (especially laying flat down). I do not regret going on this pill at all. Helped clear up all my ance and painful cyst that I had. Also made my hair less oily so I wouldn't need to wash my hair everyday. F 17 4 months
40 mg
6/28/2020
Email
 1  enlarge pore blackheads depression suicide attempts ,dry damage skin that does not heal,arthritis in many joints,knees back spine elbows,life and body destroyed by this drug. do not take roaccutane it is actual a chemo drug that nobody is told about,I was perfectly healthy before i took the drug which has destroyed my mind and body,roaccutane will eventually be banned,but not before it has destroyed everybody who takes it lives,roche i hope you rot in hell you will be held responsible M 49 10 months
20 2X day
2/3/2020
Email
 5  Severe Acne Dryness of Vagina, Lips dry, heel pains and knees Low libido, mood swings,dry eyes and watery nose It work wonders . Clears the skin properly F 32 0 days
2xD
1/5/2020
Email
 4  Acne Extremely dry skin and chapped lips, HORRIBLE dry eyes And tailbone pain whenever I sat down or put pressure on it. It worked well, my skin is nice and smooth with only the occasional pimple. 14 5 months
30 mg
1/5/2020
 1  Acne Cracked lips and ends of mouth, dry skin on face, pain on heels, knees, back pain, Rectal bleeding, mild rash on arms. I cannot walk or stand properly due to pain in heels of feets, back and knees. Cannot walk for long time and have pain while passing stool. F 25 4 months
2 tablets
1/5/2020
 1  Acne F 19 100 days
30mg
12/22/2019
 5  enlarge pore blackheads I was perfectly healthy 23 year old when given roaccutane for minor skin problem,was told there are no permanent side effects,have been left permanent damage skin that does not produce oil and has caused scarring,permanent depression and suicidal thoughts,also have now developed arthritis in many joints knees,elbows and spine. roaccutane is actual a chemo drug which nobody is told about, that has destroy my life and body ,I will never trust a dr again and as for roche and the dr that prescribed the drug I hope you rot in hell and you will be held responsible M 48 10 months
20 2X day
12/12/2019
Email
 5  enlarge pore blackheads I was perfectly healthy 23 year old when given roaccutane for minor skin problem,was told there are no permanent side effects, have been left permanent damage skin that does not produce oil and has caused scarring, permanent depression and suicidal thoughts, also have now developed arthritis in many joints knees,elbows and spine. roaccutane is actual a chemo drug which nobody is told about, that has destroy my life and body ,I will never trust a dr again and as for roche and the dr that prescribed the drug I hope you rot in hell and you will be held responsible M 48 10 months
20 2X day
12/12/2019
 1  Acne I had extremely sore joints. I could not run properly. My hip would partially dislocate. EXTREME depression (like hell on earth). Dry lips and bloody stool the list goes on and on... I took it at 16 foolishly thinking the side effects were temporary. Well I'm 27 today and I pop my back, fingers, and knees about 50 times a day. I can't eat carrots (vitamin a source) or drink ANY alcohol without feeling terrible. I defecate 8 to 10 times a day. I'm 100% sure Accutane caused this. I was extremely healthy before this. absolutely no health problems besides depression before taking Accutane. This stuff is poison. I'm sure my joints will only get worse as I age. I'm laying in bed with aching joints as we speak. I feel like I'm 50 years old not 27. No wonder they took the name brand Accutane off the market. It has destroyed people's lives. 27 6 months
80 mg
12/10/2019
 4  For acne Overall skin dryness and itching. Painful dry peeling lips. Vagina dryness and low libido painful sex. Hi guys, I was on Accutane for 6 months for my severe acne in 2017. Acne cleared and now I have very beautiful acne free skin but I’m now battling acne scars. On top of it I experienced DRY VAGINA and PAINFUL SEX and also BRUISING during sex, until the other day when I stumbled upon TREATMENT for VAGINA DRYNESS and PAINFUL SEX. Ladies my VAGINA is back to normal and gets WETS on its own without SEX or anything. My LIBIDO is still LOW but I ENJOY sex and it’s 💯 PAIN FREE. This is only for girls. I’m from Kenya 🇰🇪 Incase y’all wondering just email me I and I will reply. I understand that this can be extremely embarrassing and very stressful to deal with, I’m sorry for guys for what they are going through but I have no information on how to help. But if you’re a girl email me and keep me up on your progress. I forgot to mention that I used this cream for 5DAYS ONLY, that id so common in my place but I’m not sure if it’s available everywhere y’all at but it would be such a relief. this is NOT a hoax. Worked for me and I’m sure it would work for most of the ladies. I googled this online cos I have been keeping up with the internet to Svoid feeling alone. I’m not sure I can find this page again so EMAIL ME. Hope y’all get well soon. BYE F 25 6 months
20mg
11/22/2019
Email
 4  persistent acne I am still currently taking accutane. While yeah, the side effects are tough, it’s worth it. I still have 3 months to go and the side effects are starting to subside. In the beginning I had extreme dry skin and lips, it would cause my nose and lips to bleed. I have bad back pain, migraines and fatigue to the point that it’s hard to wake up in the mornings and I feel the need to sleep a lot during the day. This drug requires you to be tough. If that’s not you then i don’t recommend. It just depends on how bad you want good skin, and for me, I wanted it more than anything. I am already seeing results after 3 months and feel so much more confident. Best of luck to y’all F 18 6 months
30
11/14/2019
 5  Cystic acne Dry everything. Cracked lips. Bloody nose. Some fatigue. I have tried every product on the market. Proactive included. Nothing cured my cystic acne except accutane. It truly is a miracle drug, albeit with side effects. My acne started to come back after a few years, so I am on a 2nd round, which will be much shorter. I am a 37 yo female and have battled facial acne since puberty. 37 9 months
20 mg dail
11/7/2019
 1  mild/moderate acne DRUG RUINED MY LIFE. SUICIDAL EVERY SINGLE DAY 5 years later. All the tissues of my body have been irreversibly damaged - brain, nerves, muscles, joints, tendons, ligaments, skin, hair, bones. All in severe agonizing 24/7 pain. Feel like I'm burning in hell constantly, was disabled by age 22. My father being a doc sent me to his derm friend, who convinced me that low-dose accutane was 'safer than long term antibiotics'. He said all the stories and press were unfounded in science literature and not linked to accutane. Convinced me to take low dose. Was ok for first 3 months treatment, then developed ache in ankle. He said it wasn't related. Mild hair shedding. Became more depressed. Stopped treatment early, 5 months in. 5 months after I stopped, ENTIRE BODY FELL APART, severe brain damage/borderline brain dead, confused, barely able to walk or stand, pain spread to EVERY SINGLE joint in entire body with horrific cracking, skin ruined, facial fat atrophy, hollow eyes, I look 20 years older and feel 90. Developed parkinson-like tremors, suicidal depression, wished for death, burning nerve pain like I'm soaked in acid. All this happened AFTER I stopped. This is the most horrific coverups in modern medical history, a genocide of youth. I am 100% sure the literature showing 'no link' between IBS, depression, and accutane use is completely fabricated. SO MANY PEOPLE INJURED BY THIS. Even in my normal life I know people damaged by it. Completely disabled have been mostly bedbound for 5 years I am in the process of applying for euthanasia. I cry and am severely suicidal every moment of the day. I had a great life before this and was studying to become a dotor, 4.0 student, athletic, happy. ROCHE, YOU WILL BURN IN HELL. F 27 5 months
20mg 1X day
10/2/2019
Email
 1  Mild acne Aging skin. Dry eyes. Severe depression.thinning hair and skin. Please Please if you are reading my comment, i'm begging you yes i'm begging you, DO NOT TAKE the poison isotretinoin ( the active ingredient in accutane, curacne etc ..) İt completely ruined my life, i was a happy and a normal person and it turned me into a depressive, angry and a sad person,it killed my creativity, my imagination, my love of life.. İ'm not even talking about the physical effects yet like the thinning skin, my skin became so thin and crepey that i Can see clearly my veins through it, no matter what oils, butters, creams i put on it, it will never smooth out the lines and wrinkles, it became like a lizzard's skin. My hair also was affected by this poison, i had a very beautiful soft and tick long hair, my tears are falling while typing this, my hair changed completely After taking the poison, it became so thin and weak, ten years After accutane, my hair still ugly, it's shedding continuously like in a vicious circle. The Doctor or murderer who prescribed this poison to me didn't mention anything about the side effects, i trusted her because i was innocent and naive and back then i had no access to internet or to any kind of information. So i blamed myself long enough to realize that it wasn't my fault. İ pray God that whoever invented this horror, whoever prescribed it including my Doctor will be judged and punished for destroying lifes. İ'm trying to have a normal life somehow by practising sport, reading, praying a lot too F 34 1 years
20
8/19/2019
 3  Acne I am now almost 60. I took Accutane in my late twenties. I would say do not take this medication! My pores have never breathed normally. I have many scars post Accutane. I've heard from other Accutane patients that also agree that our bodies temperatures run very differently. It's not just that I am menopausal. For many years I am much too hot and my body does not sweat the same. It's as though my pores closed up and do not work normally. If I had to do it over again I would not use this product. I did have the dry lips and headaches. I have migraines now but I don't know if it's related at all. F 28 6 months
Can't reme
4/19/2019
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