ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38


More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  cystic acne on my face Back and stomach pain I haven't been on it for very long but the short amount of time I have been on it it has been wonderful to my face. I do experience some horrible stomach pain and back pain but its no worse then what feels like menstrual cramps. My mother was on accutane when she was 19 (25 years ago) and she has never had a problem with acne or anything else ever since, so I don't exactly worry the accutane will give me problems down the line. To me, its so worth it to take the drug and not have to deal with horrible painful cysts. I didn't even get normally more then one cyst at a time but I was in so much pain f.....I tried everything and my doctor finally agreed to put me on this, and I have never been happier. F 21
20 mg 2X day
11/28/2010
Email
 5  Severed Acne Dry/reddish skin, dry lips (peeled constantly) After several visits to my dermatologist, I finally decided I'd had enough of my acne nightmare (I was still in high school, need I say more). I switched doctors, and the new one immediately put me on accutane. Approximately 2ish months later, my acne was gone, completely. I've never had a problem with acne since, and I'm now 33. This was like a miracle drug. M 33
2X day
8/16/2011
Email
 5  Acne Dry lips, Dry skin, Depression
7/7/2002
 5  
1/12/2005
 4  Mild Acne on face neck back chest Dry, peeling skin. Red, watery eyes. Frequent nose bleeds. It sure has cleared my skin up! However, as with any medicine, there are some adverse side effects. I've been suffering from back pain since being on the medicine, and my eyes are constantly red. My skin peels so bad that it looks terrible with makeup on. I still would recommend this drug to anyone who wants to rid their acne. This is my last month on the medicine and i can't wait to be done with the full results! F 15
30 MG 2X day
12/23/2011
Email
 4  adult onset cystic acne dry lips, dry skin, dry eyes, permanent thinning hair that started during treatment, joint and muscle pain, back pain I took Accutaine for about 3 months but I don't remember the strength. The joint, muscle and back pain started soon after treatment ended. I never associated the pains to the medication until recently after reading what others have stated. I knew the thinning hair and other side effects were the result of the medication and figured it was worth it. Knowing now that the back, joint and muscle pains are most likely due to taking the medication I would not take Accutaine again if I could do it over again. The worst part is that my son took the medication at age 17 and he started having back pain (disc related). He regrets taking Accutaine and I regret encouraging him to take it. F 58
1X day
6/7/2010
 4  
1/26/2007
 4  Mild Acne- Hated The Blackheads I have only been on this treatment for 2 weeks and i am feeling rough. My twin sister was on this for 6 months last year and only experienced the basics side affects that everyone seems to get no matter what...extremely dry lips & face and the occasional mood swing. However she was started on a lower dose then me even though her acne was alot worse. I thought id be fine but im really not. I have upper back pain most of the time and the occasional chest pain. I get blurred vision and my eyes are killing me! Headaches on and off and im tired alot of the time,which doesnt change much actually as i do shift work but it is making it hard. Im definately not coming off the medication as i know it works but i know its gonna be difficult. Im just hoping that these are all i get. I can handle mood swings and the dry lips & face, just not the constant pain and the headaches. I would still recommend it as not everyone gets the same problems....my twin is the prime example.....she sailed through!!! She looks radiant and i hate her for it! :-P My sister is just generelly better now, psycially and mentally then she has ever been. F 20
10/22/2009
 3  Severe acne Dry lips, soar back, overall very few side effects I am currently still on accutane and so far I've been very pleased with my results. I am only 18 but my issue is will this harm any babies that I plan on having later on down the road like 10 years or so from now?? F 18
60 1X day
5/17/2010
 3  acne I am feeling very uncomfortable. My back hurts and my joints ache. I am tired to the point of needing to take a nap everyday. I used to play in the yard with the kids and I feel like I have no energy to do that and I also have such bad muscle cramps that I am afraid to use them. No headaches- just bad aches and pains. The dry lips are tolerable. I am wondering if anyone else has this problem and how long it lasted. It seems like there is a range of symptoms associated with the drug. I am 41, have mild acne but tired of the scars it leaves. Should I preserver? I have been on it about three weeks- have a pretty good breakout currently, and hope it works in the long run to make it worth the pain it causes. F 41
1/8/2009
Email
 3  Cystic Acne Dryed out skin, lips, dehydrated I took this drug when i was 15 for however long the treatments are. (It was a while ago) The side effects were bearable, mostly just dried out and thirtsy, but my acne went away for the time being. After a few months of being off of it, my acne came back just as bad as before. The younger you are when you use the drug, the more likely the acne is to come back. This time around i have been prescribed bactrim and use differin gel on my face and i have PERFECT SKIN. I never thought i would be able to try anything else since i already had to resort to using accutane, but this works for me. I had to be patient as it got worse before it got better, but i have been on the new treatment for quite some time now and i will continue it forever to have the beautiful skinthat i do now. F 21
8/19/2008
 2  the usual reasons Most of the side effects associated with taking Accutane are the same as for vitamin A toxicity. If you are considering using this drug please read information on vit.A tox. in addition to the literatue on Accutane. Taking it is essentially putting you into the same physical state and it's a coin toss as to what extent of damage you'll receive. No one, doctor or otherwise, can tell the outcome you'll have on it. What is your gut reaction, your intuition, when considering to take it? Listen to yourself. Best wishes, truly, best wishes. F 30
1/25/2006
 1  acne I had very dry skin, however when I was finshed I broke out with a terrible rash that I still have. It covered the side of my face and got worse. I still have it and have since I got off of accutane. I still have mild break outs. To me I would rather have acne then a rash that breaks out over my body that hurts and itches. F 17
10/22/2006
 1  acne cystic PERMANENT BACK/JOINT PAIN! DEBILITATING MED! I took Accutane in 2001, and I haven't been the same since. I was a healthy nurse working full-time, taking care of 2 small children, and kept an immaculate house. THEN, ACCUTANE RUINED MY LIFE! I haven't been able to nurse full-time or work full-time for that matter. I can no longer walk long distances b/c the back and joint pain is so SEVERE. I've been taking arthritis and pain meds for years now. Every time I try to come off, the pain is absolutely unbearable. I manage if I take my meds and be as active as the pain will allow. I also have a bladder disease, poor eyesight and thinning hair. This med is like chemo; it ages your entire body. My skin looks 10 years older than I am, and I still have acne! If you've taken it and have the same permanent symptoms, I feel so bad for you. You may email me, if you'd like. BEWARE,IT'S NOT WORTH IT! F 39
? 1X day
8/12/2010
Email
 1  acne-father insisted M 26
30 mg 1X day
10/20/2011
Email

Patient History
 1  
1X day
6/3/2012
 1  acne In the Roche pamphlet it is stated that the EXACT mechanism of isotretinoin is unknown. This information isnĄŻt all wrong, but the truth is that the mechanism of isotretinoin is pretty well known. It just hasnĄŻt been proven 100 % by lab essays. Well here are the hypothesis on how Roaccutane gets rids of acne. IĄŻll try to keep such a complex thing as simple as I can for everyone to understand. Roaccutane (isotretinoin) is a synthetic retinoic acid. The body uses retinoic acids to regulate gene expression!!. Gene expression!! means the way that cells are created (simplified a lot). Cells to be created needs transcription and replication of DNA. To put it simple, itĄŻs like making a cake. You need the ingredient list to be able to make the cake. The body needs DNA to be able to make the cells. Retinoic acids comes in this process by regulating the gene expression!!. It means that retinoic acid is a part of the creation of the cel In the Roche pamphlet it is stated that the EXACT mechanism of isotretinoin is unknown. This information isnĄŻt all wrong, but the truth is that the mechanism of isotretinoin is pretty well known. It just hasnĄŻt been proven 100 % by lab essays. Well here are the hypothesis on how Roaccutane gets rids of acne. IĄŻll try to keep such a complex thing as simple as I can for everyone to understand. Roaccutane (isotretinoin) is a synthetic retinoic acid. The body uses retinoic acids to regulate gene expression!!. Gene expression!! means the way that cells are created (simplified a lot). Cells to be created needs transcription and replication of DNA. To put it simple, itĄŻs like making a cake. You need the ingredient list to be able to make the cake. The body needs DNA to be able to make the cells. Retinoic acids comes in this process by regulating the gene expression!!. It means that retinoic acid is a part of the creation of the cel
8/20/2008
 1  cystic acne I did two rounds of that crap in 1997.My skin cleared up.However I started having heart palpitations which have not stopped now for several years. Will they ever stop? Would I trade clear skin for these disturbing side affects? No, I am scared about what the future holds. This is a scary drug. I would never do it again F 48
1/8/2005
 1  cystic acne I did two rounds of that crap in 1997.My skin cleared up.However I started having heart palpitations which have not stopped now for several years. Will they ever stop? Would I trade clear skin for these disturbing side affects? No, I am scared about what the future holds. This is a scary drug. I would never do it again F 48
1/8/2005
 1  Acne Crohns Disease, Hair Loss, Depression Developed Crohns Disease (internal bowel disease) within 6 years of taking Accutane. Also hair loss started at 25. No genetic trace of either in my family. Depression could have been partially genetic, but not to the length I went through while taking it. M 35
6/1/2007
  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

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