ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  cystic acne for years chapped lips, dry face, some muscle pains. First off Accutane is absolutely amazing, I do not know why I didn't start it earlier. I've never been happier in my life, I noticed results after a week and a half of being on the drug. My oil stopped dead in it's tracks and my pores shrunk! Absolutely amazing! My face is so firm and tight because I no longer have big pores. I never broke out badly, only a few pimples on my chin, none on my cheeks or forehead. It greatly reduces the appearances of the red marks also, I think maybe due to the shrinking of the pores. I have two months left on accutane, I'm on the 20 mg, but as of now I'm completely acne free. The first two weeks you will notice all of your blackheads rising to the surface and you can just rub them off. My face is flaky at times but never oily! The only problems I've had while being on Accutane is, yes you do get very chapped lips, not really that big of a deal though, no loss of hair (my hair actually looks healthier because it cleared up the oil in that area F 2 months
11/21/2006
 5  Acne Dry lips, Dry skin, Depression
7/7/2002
 5  
1/12/2005
 5  acne Like everyone else, very dry lips. To the point where it was difficult to smile sometimes. Dr. gave me some protopic ointment and it helps. Dry bloody nose, dry patches on arms, very sensitive to the sun, minor back ache This medication has worked for me. Other then the side effects already listed, my skin has finally started to clear up. My dr. anticipates another month or two of continuing the medication until completion. The first 4-5 months were disappointing. Still had lots and lots of breakouts and my poor lips were going through hell (still are). However, now that I'm almost done with my 7th month, my skin looks great. Very clear and very smooth. I never experienced any of the depression or sadness. I definitely recommend using the medication if you are approved to do so. It took me a long time to find a dr. who would prescribe it to me. The monthly blood test are kind of a pain, but trust me, the results are worth it. Hang it there!! 7 months
7/20/2007
 5  Severe Acne Dry cracked lips, very dry face Accutane is a God send. It cured my severe acne in 4 months after trying EVERYTHING for 3 years. F 4 months
40MG 1X day
4/6/2014
 4  Sudden severe acne at age 38 Dry & cracked lips, pain in toe joints, slight pain and stiffness in knees and other joints. Not sure if pain is due to accutane. Seem to have less taste. Back aches...not sure if related. Antibiotics didnt work after 1 year. The drug cleared my acne after getting worse initally. My extremely oily skin is much, much better and more comfortable. Not sure if there are hidden side effects yet to come. I am very cautious especially since doctor advised me to go on drug for a year. Will consider seriously long term use. 100 days
10/23/2005
 4  Cystic Acne Very dry lips, decreased sex drive, tailbone, hip and muscle pain, dry\itching\burning eyes, patches of dry skin. Been taken accutane for about 7 weeks and it has helped. I did not understand the tailbone pain until I read this site. M 45 days
1/21/2006
 4  
1/26/2007
 3  Moderate Acne Chapped lips, Bleeding gums Im optimistic about treatment. Yet this is pretty serious stuff. Within a week my lips were getting chapped pretty bad. Also, last night I brushed my teeth to a crimson surprise. I have pretty decent dental habits and history. I experience mild gingivitus time to time and it usually solves itself with good brushing and some listerine. This time around, I couldn't believe how much blood there was. Fortunately, this morning wasnt so bad. The sore seems to be localized to one tooth. I really hope this is worth it.... 25 days
8/22/2005
 3  acne 1 days
11/6/2014
 1  
1X day
6/3/2012
 1  acne In the Roche pamphlet it is stated that the EXACT mechanism of isotretinoin is unknown. This information isnĄŻt all wrong, but the truth is that the mechanism of isotretinoin is pretty well known. It just hasnĄŻt been proven 100 % by lab essays. Well here are the hypothesis on how Roaccutane gets rids of acne. IĄŻll try to keep such a complex thing as simple as I can for everyone to understand. Roaccutane (isotretinoin) is a synthetic retinoic acid. The body uses retinoic acids to regulate gene expression!!. Gene expression!! means the way that cells are created (simplified a lot). Cells to be created needs transcription and replication of DNA. To put it simple, itĄŻs like making a cake. You need the ingredient list to be able to make the cake. The body needs DNA to be able to make the cells. Retinoic acids comes in this process by regulating the gene expression!!. It means that retinoic acid is a part of the creation of the cel In the Roche pamphlet it is stated that the EXACT mechanism of isotretinoin is unknown. This information isnĄŻt all wrong, but the truth is that the mechanism of isotretinoin is pretty well known. It just hasnĄŻt been proven 100 % by lab essays. Well here are the hypothesis on how Roaccutane gets rids of acne. IĄŻll try to keep such a complex thing as simple as I can for everyone to understand. Roaccutane (isotretinoin) is a synthetic retinoic acid. The body uses retinoic acids to regulate gene expression!!. Gene expression!! means the way that cells are created (simplified a lot). Cells to be created needs transcription and replication of DNA. To put it simple, itĄŻs like making a cake. You need the ingredient list to be able to make the cake. The body needs DNA to be able to make the cells. Retinoic acids comes in this process by regulating the gene expression!!. It means that retinoic acid is a part of the creation of the cel
8/20/2008
 2  mild acne on cheeks, forehead, chin chapped lips, dry skin on hands and face i started taking accutane because 3 medications before this did not work. Much of my acne is gone, but the side effects are still ever present... i would not take this if you are having puberty related acne, because that type tends to go away, but for adult acne, this is better. F 13 2 months
5/20/2008
 5  acne Very very dry lips (keep chapsticks all over the place!), sensitivity to sun but not terrible, very minor joint pain. My daughter, age 14, just finished 5 months of Accutane/Sotret is the generic, (after four miserable years of every antibiotic and topical treatment, laser therapy and naturopathic remedies) - FINALLY her skin is CLEAR and she is thrilled with the results. Beforehand I had read askapatient.com comments plus other info and I was scared about hairloss, depression, jointpain, etc.so I was very reluctant for her, especially at her age, to go on Accutane. But after everything she had tried, she was so discouraged and selfconscious; her dermatologist said that she has treated patients with Accutane for 20+ years with very very minor problems,(it turns out the same ones that our daughter had), almost everyone was pleased with the results so we decided to go for it. Relative to everything else our daughter tried, this has been an easy treatment, (the real hassle is the FDA requirements of monthly blood tests and online questions which seem ridiculous). Her clear skin has made a huge differ F 14 5 months
8/28/2008
 5  bad acne very chapped lips, lower back pain, pain in tail bone, dry and tired eyes, red face, sun burn easily, sore muscles in butt and groin area after hard running i first got acne in the 6th grade and each year it got significantly worse, i tried all other solutions but none worked. accutane is a miracle drug, it works, im on my 5th month of this drug and i have perfectly clear skin. this drug is great. although there are some bad side effects, it gets rid of your acne. if u play a sport, dont take accutane while ur sport is in season, u most likely will not be able to play with the side effects of accutane M 14 5 months
12/11/2005
 4  bacne dry lips, tiredness, anxiety, flare-ups in the first week I got an accutane prescription after trying everything else-- creams, antibiotics, you name it, I used it at some point. I'd heard about all the side effects. On the first day I got a painful acne cyst on the side of my nose, which was unusual for me because I don't get facial acne. It's reduced oil gland production, I can tell. And I have the usual dry skin, lips, etc. Hope it works!! Seems like it so far... F 14 5 months
40 mg 1X day
1/10/2011
 4  Pretty bad acne on face Back is a bit sore, sometimes headaches, lots of poo (maybe it's just me that's been going on before I took this) peeling skin on my face, chapped lips (the corners of my lips are the worst at the moment) constantly sleepy (but I'm always sleepy being a teen) If you want the results you want, then you should deal with the pain. Many good things come with a cost. It may not be for everyone. Hell, I don't even know if I will get the FULL results with me being on 3 more medications. It's been only a few weeks so far, and it's actually doing well, therefore I would recommend this. F 14 1 months
forgot .-. 1X day
10/27/2014
 4  Acne Extremely dry skin and chapped lips, HORRIBLE dry eyes And tailbone pain whenever I sat down or put pressure on it. It worked well, my skin is nice and smooth with only the occasional pimple. 14 5 months
30 mg
1/5/2020
 3  resilient acne FREAKING DRY LIPS, mood swings, lots of crying for no reason, a lot of back pain (lower when getting up from sitting) and (upper when going to bed), dry skin (but not flaky or peeling), dry eyes, lots of knee joint pain (after running you're really shaky), and I always want to sleep (I can never seem to feel rested) This stuff is hardcore, you have to be sure that it is worth all the side affects for clear skin, because as much as I want clear skin and to feel great about myself, it sucks to wake up everyday feeling tired, dried out, sore all over your muscles and bones, and upset. Your healthy and general happiness is definately affected, because you never feel yourself, there is always some nasty side-effect holding you back, so all i have to say is make sure it is worth it to you :) get in contact with me if you agree with any of this, I've barely started treatments and I would love to talk to someone my age going through the same thing. F 14 3 weeks
5/12/2007
Email
 5  Severe Acne Dry lips, hip pain and muscle soreness I am in my last month of a 7 month treatment. It took 6 months to work, but it truly is like a miracle drug. My face is almost completely clear! I have 3 weeks left. I just hope it lasts. The blood test were a pain in the neck, but everything was normal. M 15 7 months
6/18/2007
  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

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