ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  cystic acne back acne worked great - but did have dry skin and very dry lips. Please check out my full review under Zenatane. https://www.askapatient.com/viewrating.asp?drug=202099&name=ZENATANE M 16 6 months
30 1X day
9/8/2023
 3  chronic acne Accutane worked amazing clearing my chronic acne i've been battling since the 6th grade, that being said i have experienced extreme hair loss. Will my hair come back? it has almost been 9 months since i have stopped taking accutane M 19 1 years
15 2X day
11/4/2022
Email
 5  Acne dry lips I had cystic nodular acne on my face, back, and chest. I've tried every acne medication under the sun! So happy I've purchased Accutane (Qacne365). It worked great and I could tell a difference within a month of using it. It's been 3 years since I took it and I'm still all clear. I would recommend Accutane to anyone with acne. M 24 60 days
60 1X day
9/13/2022
 1  cystic acne I started getting mild stomach issues towards the last 2 days of taking accutane. i stopped it immediately but it was too late. The permanent damage its caused to my body ruined my life forever. A few months after I stopped accutane, my digestive issues got 100x worse and I developed new conditions. I have since been diagnosed with inflammatory bowel disease, autonomic dysfunction, POTS, peripheral neuropathy, and degenerative disc and joint disease. I am disabled now. Several years later and I am still disabled, getting worse every year. and this was from a LOW dose. This stuff is pure poison. This will ruin your life and all the serious effects happen after you stop F 27 3 months
20mg 1X day
6/24/2022
 1  Nodule acne I have struggled with weird skin issues for years. Dermatologists always prescribed topical meds and nothing worked. I have itchy inflamed knots under my skin. Mostly on my face and some on my neck. They never fully go away except when I took steroids for another skin rash condition caused by allergy to another med. my new dermatologist put me on Accutane confident it would cure. 7 months nothing. I had horrible skin, new eczema developed, depression, horrible peeling lips, and I started feeling lethargic. She wanted me to keep taking it 10 months but I don't have insurance and it was so costly. I had to quit. I felt it was doing more bad than good. Now I've been off it a month and my health is declining. I got a bad yeast infection, vomiting, lethargic, dizziness, massive weight loss, trouble eating, and my skin is even worse on my face now. DO NOT PUT THIS TOXIN IN YOUR BODY Would love to know if anyone else has similar health issues now. What has helped? I am going to see a functional doctor next. F 38 7 months
1X day
4/15/2022
Email
 1  Folliculitis I used 20mg of accutane for only 10 days before I developed ringing in my ears and quit immediately. Unfortunately it was too late and the damage was already done. 3 years later and I still have daily ringing in my ears, and since then I've developed even more health issues which my primary doctor thinks are caused by the drug. Cracking in my joints, dry eyes, migraines, erectile dysfunction, and floaters in my eyes. All of this from 10 pills. It's hard to believe how destructive and poisonous this drug can truly be. If I took a single more pill, it probably would have killed me. It's pure poison, and clearing the skin is simply a side effect of your entire body getting poisoned. It's ridiculous and concerning that this treatment is considered safe and given to young people. M 29 10 days
20mg 1X day
1/4/2022
Email
 1  Cystic acne I took accutane about 30 years ago (I was in my mid 20's) when it was first introduced / new on the market and back then there were very little warnings for all the possible risks and long term effects. Since taking it, over there decades my health has been a slow but continuous decline in ways that aren't explainable by my genetics. My siblings are all healthy; my parents never had any of the health issues I've suffered from. I felt fine while using accutane. What nobody warned me about is what would happen to my health and body in the aftermath of using this drug. Had I known it was a chemotherapy I would have of course never touched it, but this information wasn't disclosed (intentionally, perhaps?) to me. Who would take this drug for acne (no matter how severe) if you know it's a cytotoxic chemotherapy??? NOBODY… well, only insane people. In the past 30 years I have developed damage to virtually every part of my body. By age 30, I had lost half my hair and couldn't work out normally anymore due to pain and stiffness in my joints. My age 35, I developed seriously dry eyes and some new digestive problems. I struggled with infertility throughout my 30's and was never able to conceive, despite trying many times and seeking fertility assistance. By age 40 I had serious bone pain, arthritis, and MRI showe If you're reading this review thinking of using accutane, keep in mind that after ingesting this poison you will live the rest of your life not knowing how it will possibly ruin your health and body insidiously in the future. PLEASE READ THIS: zero.sci-hub.se/902/294a852b5aa6cb77485c16eeed8d6126/goulden1994.pdf The number of patients reporting either transient or persistent symptoms during the follow-up period was 74 (10-3%). Onset of symptoms ranged from 6 weeks to 10 years after stopping therapy. M 54 4 months
40mg 1X day
1/2/2022
 1  Cystic acne Accutane will ruin your health. It isn't a matter of IF but rather WHEN. I felt more or less fine while using this drug 5 years ago. Blood tests, the usual normal symptoms, dry skin lips hair etc. Things were normal, I was working out, going to school, etc. It wasn't until the following years that my health problems all started. A few months after the course ended, I started losing massive loads of hair and my eyes became dry. They have progressively gotten worse over the years. Then, 3 years later, joint pain- in my elbows and knees at first, but soon after it spread everywhere in my body. Accutane will damage your health in the future, it's not matter of "if", burather "when". M 28 5 months
20mg/day 1X day
1/1/2022
 4  Cystic acne I had bad depression,dry eyes and dry skin,lots of appetite or gain of appetite, runny nose. Please only take this is its absolutely necessary it works wonders but the side effects are what get you :) F 19 5 months
30mg
12/14/2021
 1  Acne on face and back. Erectile dysfunction and no orgasm. I can ejaculate, but I feel literally 0 orgasm. Loss of libido. Avoid. Try exhausting other methods to clear acne. M 22 1 years
12/1/2021
 4  To clear my skin Dry lips.. joint pain.. light sensitivity.. blurry vision.. hair loss.. rashes.. fragile skin.. sensitive eyes.. nose bleeds every day for 6 months.. lack of sleep.. aggression.. depression.. lack of concentration.. dizziness.. fatigue.. lower back pain.. anxiety .. stress inducing dreams.. loss of appetite.. dry eyes.. cracked mouth.. body aches Besides all the symptoms the drug did what I wanted it to.. just take precautions M 17 6 months
20mg 2X day
5/18/2021
Email
 3  Severe Acne I believe it helped my acne out a lot. My dermatologist paired it with an anti inflammatory and a steroid (cephalexin and prednisone.) I'm a lifter and have severe inside elbow pain, low back pain, shoulder issues, and chapped lips. apart from that no other side effects. M 17 8 months
40 1X day
3/30/2021
Email
 4  Acne Dry lips Dry eyes Blood noses but taking it at 42 I realised you can prevent blood noses by nasal spray products Didn't sleep well not sure if that's me or the drug I took this drug at 15 years old 20 mg I already was depressed from just having bad acne. I took it again at 16yrs this time 40 mg. Then it came back after a year stronger than ever. I then went back on it 40mg but I was young and just took it when I felt like taking it. I then went back on it at 21 years of age but had bad depression and anxiety so I stopped. I used creams after that. Tried to go back on it at 25 yrs age felt very depressed I had to stop due to my teeth hurting me at the time. So many year on I still struggled with my acne. I had kids at 32 yrs and another at 35yrs my skin was manage with creams. I began to Get large pimples on my chin which left big scars so I have just recently gone back on. I have finished my course and didn't feel depressed or anxious. My skin has improved but I am going back for a stronger dose. It's been a long journey for me. I still would take it nothing else really help but this. For me I am not sure if accutane causes depression or acne causes it. I don't have any other health problems all these years later. F 42 6 months
20mg to 40 4X M
3/26/2021
 1  Polycystic Acne I took Accutane many years ago...13 years ago to be exact and I still suffer from cracking joints, chapped lips, dry scalp, dry skin... the list goes on. The cracking joints are embarrassing as I'm only 34 years old. I've waited years for it to stop and it has not. I'm glad I found this thread. I'm going to try taking vitamin D and see if it helps.... I'm seeing a Dr now to try to get to the bottom of it. On top of all of this....I Still Have Acne F 21 6 months
Don't reme 1X day
3/13/2021
 1  moderate acne After a couple of weeks I felt that something had changed in my head. I went from being confident and happy to feeling extremely anxious and tearful. 2 months after stopping this drug I became psychotic and felt suicidal. I also then realized that I could no longer get an erection. Nobody knew how to help me, my psychiatrist told me that I was just depressed, I knew it was the drug. Six years on and I still suffer with debilitating depression. Nobody warned me of the hideous side effects. This is a chemotherapy drug and is an overdose of vitamin A. It causes permanent brain changes and is causing misery to thousands of young people. It should be banned totally and the victims compensated for having their lives ruined by incompetent dermatologists. M 26 28 days
20 2X day
2/24/2021
 4  Persistent acne I had a lot of side effects with this drug such as hand joint pain, constipation, anal fissures, tail bone pain, dry skin, hair loss, dry eyes, decreased night vision, chapped lips, vaginal problems, persistent thirst, and I am always out of breath when exercising. It definitely helped clear my acne, but I think I was on it longer than needed. After two months my face was completely clear but I stayed on it for three months after that. I am definitely glad I took it, because I was very self conscious about my acne. But I don't think I would choose to take the drug again just because of how many side effects I have had. F 20 100 days
30 mg 2X day
2/22/2021
 1  mild acne Erectile dysfunction, low libido, depression, anxiety, PTSD suicidal ideation. suicide attempt. permanent joint pain. Loss of muscle man and no longer able to make gains. ruined skin can no longet tan, loss of hair. aged considerably. Isotretinoin destroyed by life and these side effect are not rare. Research before you take it. Go on forums and believe what victims are saying M 31 8 months
60mg 2X day
2/20/2021
Email
 1  minor skin problems every body that takes roaccutane are going to end up with permanent damage arthritis all the joints,you will not be able to move 10 to 20 years after you have taken the drug roaccutane is a chemo drug that has destroyed my body and life.everybody who has taken this drug needs to see a lawyer, roaccutane is a chemo drug that destoys lives,everybody needs to see a lawyer for permanent damage M 49 10 months
40 1X day
12/31/2020
 4  Nodules, pus-filled acne HALF MY THICK HAIR FELL OUT it was totally abnormal and I've never had this much hair fall. It also became thin and lackluster. I couldn't even tie it. Hyperpigmentation got worse as I lost so many skin cells on my face and arms. Skin feels tight. Red patches on face that come and go. Dry eyes and sight was unclear at night-you shouldn't drive. Frequent headaches. Really depressed and it makes everyday life and normal activities very difficult. It works but the side effects are definitely not worth it. It's surely not an easy medication to take. My acne scars are still there and my face is kinda red (I have dark skin). I'm currently using bioderma sebium hydra post-accutane. Only use it if nothing else works (I was on treatment for 6 months before e.g. doxy, adapalene, antibiotics etc) and be sure to moisturize frequently (try something non comedogenic) F 17 3 months
20MG 2X day
11/10/2020
Email
 1  Chronic Cystic Acne Loss of almost all scalp hair, still losing it, loss of eyebrows, lashes and body hair, change of colour, texture, thickness, elasticity of hair before it fell out. Conjunctivitis, permanent eye pain, problems with night vision, dry eyes, back pain, scalp pain, earache, joint pain, cracked bleeding lips, strange ridges in finger and toe nails. TOXIC POISON. My dermatologist repeatedly recommended this to me, as a safe natural vitamin A product which would cure me in a short time, unlike long-term hormones, and the worst I could expect was to feel uncomfortably dry. I asked him 2-3X about any effect on my (beautiful, thick, curly red hair) and he assured me the effect was just temporary dryness and that as soon as I stopped taking Accutane all side effects would cease. Every time I expressed concern he would say to me : "Who's The Doctor??" I agreed to try it. After three months I stopped and that's when the hair loss started. I had never had a problem before and was not on other meds. What all the experts I subsequently consulted called Telogen Effluvium became chronic and never stopped. The doctors all denied it was related to Accutane! They're still prescribing it. Hoffman LaRoche isn't suffering, my dermatologist (now comfortably retired I expect) never suffered, Health Canada who approved it never suffered. They're all responsible for destroying my life and clearly others' but didn't pay even as much of a penalty as someone who steals a loaf of bread to keep from starving. Dr. L. S. in Montreal, I pray every day that YOU in particular rot in hell. If your doctor suggests you take this garbage, ask him/her first if they are willing to pay for your wigs. I'm thinking, no. F 59 90 days
40 mg 1X day
9/26/2020
Email
  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

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