ALLOPURINOL Reviews (ALLOPURINOL)

Average Rating: 3.0 (212 Ratings)

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 ANTIGOUT

 Type: Rx Drug

  

ALLOPURINOL  (ALLOPURINOL):  Allopurinol is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. These patients can have increased uric acid levels due to release of uric acid from the dying cancer cells. Allopurinol works by reducing the amount of uric acid made by the body. Increased uric acid levels can cause gout and kidney problems.   FDA Approval Date: 1986-10-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ALLOPURINOL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ALLOPURINOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Gout Abdominal spasms and cramps, bloating and excessive gas, pressure on bladder GP told me to stop taking it F 63 10 days
100mg
11/28/2018
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 3  Hyperuricemia On higher dosage, I developed irritable bowel symptoms, like intestinal cramping and loose, urgent stools three to four times a day, followed by stomach ulcer symptoms (constant burning, gnawing feeling). Lost 27 pounds in three months. I started Allopurinol due to very high uric acid levels. I did have a few gout attacks over the years, but it was not constant. Still, high uric acid can lead to other health issues. My doctor started me on a low dosage (100 mg per day) and increased over four months to 400 mg a day. My uric acid level came down to normal. A month after the increased dosage, I became very ill for six weeks with the symptoms I've mentioned. I could barely eat or function. I had a slew of blood tests, stool tests, barium swallow and abdominal ultrasound to find the source of my G.I. issues. All test were normal. Doctor cut back the dosage to 200 mg. a day and after six weeks of suffering, my symptoms resolved. My doctor is still hesitant to admit that the higher dosage caused these issues, but I am convinced that it did. I'll continue taking Allopurinol at this lower dosage. Hopefully, I'll have no further issues. F 61 7 months
100 2X day
8/5/2018
 1  High blood Uric acid SEVERE fatigue, Brain Fog, Joint Pains, All day sleepiness...god knows what else allopurinol did, it’s hard to tell or pay attention to anything when you’re half asleep (zombie) for years while taking it. My dosage was increased slowly and every medicine has drowsiness as a side effect. I’m sure that together both these things made it hard for me to connect side effects to the medicine. Once I had taken it long enough it was like I was a zombie most of the time. I thought I had some kind of cognitive problem I.e. Alzheimer’s, brain tumor etc... I saw all kinds of doctors (gastroenterologists, allergists, neurologists, endocrinologist etc) looking for answers but not one said that maybe it was the allopurinol. My testosterone was low, my vit D levels were low, high blood pressure, high cholesterol etc... After adjusting my diet and stopping the allopurinol (by chance) my pressure went back to normal, I was able to go to the gym and keep going, I feel half alive/awake again. Going to see my doctor soon to see what my Uric acid numbers are, testosterone, cholesterol etc off this medicine. Allopurinol is an adenosine agonist, this effect is probably (maybe not the only thing) why this medicine causes drowsiness, fatigue, brain fog. adenosine makes you sleepy (caffeine blocks adenosine). M 37 8 years
300 1X day
6/4/2018
 1  Gout altered vision, inability to focus eyes clearly, twitchy muscles around the eyes, fatigue, diarrhea What has happened to my vision on this is pretty strange, it is super intense after reading a screen (iphone) - I can still see far away but have a hard time bringing distinctness (faces) into focus. They are not blurred though. Also, perpetual twitching around my eyes. The other stuff I can handle, but would rather have a gout flare and not be able to walk than deal with my vision being affected like this. M 43 4 months
100MG 1X day
5/10/2018
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 3  Gout Very sore knees and muscle aches , small gout attacks , heavy legs and sore feet . Was warned to give this drug time , it's not a pretty ride to get your body used to it , better than a severe got attack , must be aware that this drug removes old crystal that are built up in the joint , very painful to start with but I will battle through . I have been told it can take up to 8 months or a year to be affective . Good luck gouters M 90 days
250
11/27/2017
 4  Gout and Kidney Stones Muscle aches and my legs feel like lead weights at times. I'm a runner and it seems like I am somewhat out of shape since reaching 300 mg when I run, but it's only been 3 months. So far it beats having gout. M 59 3 months
300
8/19/2017
Email
 1  gout severe pain from right foot to knee.made my eyes seem to look up and slightly to the right with burning and slight sting.this i cant swear to this but im pretty sure it caused cellulittis in my right lower leg theres no other reason i can think of as i never had it in my leg before and it started in just about 3-4 days after takeing the allopurinol so i trashed it down the toilet.my advice is stay far away from it. M 62 0 weeks
100mgx2 da
6/14/2017
 1  Kidney Stones This drug is awful! Severe anxiety, severe insomnia, dry mouth, brain fog, stomach pain, back pain, joint pain, hair falling out, blurred vision, toe numbness and crying for no reason. Stopped taking the drug after researching it and the anxiety, insomnia, brain fog and crying stopped the next day. Still having some residual effects on my stomach and joints. Make sure you're aware of any changes when taking this drug. Took me 4 months to put two and two together. F 50 4 months
300 mg
5/22/2017
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 4  gout Weak legs F 61 1 days
once a day
3/4/2017
 3  High Uric Acid Level After taking this drug for 4 months with no side effects all of a sudden my legs feel like lead weights and my knees are as sore as can be. This onset occurred after taking amoxicillin. I have gotten gout attacks in the past but I had them under control with diet & hydration. Doc still wanted to get my uric acid level down (was 7-8) so I agreed to this Rx. I am having second thoughts now with this sudden on set of side effects. Someone please tell me this will pass - I do not want be a cripple at 50. M 50 4 months
100 MG 1X day
2/27/2017
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 5  Gout attack and high uric acid Slight weight loss so far, and great reduction of size of several lipomas I think the med affects appetite somewhat which I am quite happy about with a need to lose 30 pounds. Have lost 9 lbs. so far after 6 weeks use. Also shrinking of my lipomas is occurring since I started this med. and have no other variables during this time. F 63 6 weeks
100 1X day
2/23/2017
 5  Painful gout for 30 yrs No side effects A life saver, takes patience in beginning treatment but pain free afterwards, have to give pill time to work. M 57 1 months
200mg
2/21/2017
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 1  high uric acid level Dreadful fatigue & weak. Chest & neck pains; thought I was having a heart attack. Numbness in front of legs. Rash & itching. Gout in finger. Diarrhea. Cold sweats. Sleep disturbances. I stopped this drug and would NEVER take it again. I would rather put up with an attack of gout to the dreadful side effects this drug causes after just 5 tablets.It is now 5 days since taking allopurinol and still suffering the side effects F 5 days
100mg 1X day
2/21/2017
 4  High Blood Uric Acid. MGUS Night sweats (MGUS Cancer related most likely), fatigue and depression. The removal of calcites also caused severe kidney pains in removing the these deposits (4x attacks x5hrs extreme pain). Ringing ears and temporary hearing loss. No skin rashes or other major side effects. All seems to have eased after 2 months of daily 100Mg. M 60 2 months
100Mg 1X day
2/6/2017
 1  Gout and Kidney Stones Immediately experienced body pains (side, jaw, back, shoulder) accompanied with dizziness, and followed by chest pain. Since taking medicine a month ago, still experiencing periodic high blood pressure, chest, and joint pain. M 45 1 times
20 1X day
1/29/2017
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 3  Gout. nausea, occasional diarrhea. food aversions - haven't eaten meat or anything else greasy or had a glass of wine since starting drug. i've lost 10 pounds, which, frankly isn't a bad thing. but i am a person who really enjoyed cooking and eating before this, now i have a couple bites of anything, and push it away in disgust. i may keep on the drug til i lose another 20 pounds but i'm really hoping there's no other of the side effects everyone else is talking about lurking! has anyone else's side effects lessened with time? my gout pain is definitely lessened since starting the drug a couple weeks ago. the side effects RUINED thanksgiving dinner, though! F 51 14 days
300mg 1X day
12/5/2016
 2  Uric acid levels elevated After 30 days I noticed cramps in legs and twitching in several muscles. M 53 1 months
100mg
11/21/2016
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 3  Ulcerative Colitis Foggy, rash, mild depression, tiredness, inability to concentrate, sore kidneys, personality changes - on days where i've forgotten to take it I feel great.... F 24 1.5 years
50 1X day
9/5/2016
Email
 1  To lower uric acid Brain fog chest pain confusion lethargy. Discontinued after reported to doctor all my symptoms and was ignored. Focused only on chest pain even after all tests at e.r. disproved heart. Told e.r. doctors were wrong and made mistake. M 54 1 months
200
8/24/2016
Email
 5  for the gout Pain all over F 60 1 days
100mg
7/31/2016

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