Drug Ratings for ALLOPURINOL

Average Rating: 3.3 (145 Ratings)


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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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RATING  REASONSIDE EFFECTS FOR ALLOPURINOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
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 5  gout ED (yes it can cause it), cataract, tired, headaches, high billyrubin, after reading some of the comments I will share some of mine...drink more water, cut back on the alcohol, cut back on the red meat. I heard cherries or cherry juice helps. as for being tired take it at night...less chance of being tired. if need to see if taking smaller doses twice a day better then one big one. M 39
200mg 1X D
2/17/2010


History
 5  gout Never knew there were side effects until recent articles. Hence, I have to say I had none. I have had high uric acid levels most of my adult life. One morning some 20 years ago I woke up with a classic big toe gout attack. Following treatment for pain, I started taking allopurinol. I take one tablet each morning. I have had no symptoms since starting it. M 80 20 years
300mg 1X D
4/14/2010

 5  early gout onset none I diagnosed my first gout attack and had it confirmed by hospital er blood test. I pressed my doctor for a uric acid remedy because I realized through some research that gout is self sustaining. The more joint damage the more attacks. He prescribed allopurinol. It works. I have had no attacks and have not suffered the joint damage that would make me over-sensitive to uric acid levels. I eat whatever I want.(within reason) My mother and a friend were poorly handled and only given anti inflammatory. I recomended allopurinol and it has helped greatly but their joint damage still allows for occasional attacks. allopurinol, don't wait! M 55 12 years
150 1X D
5/7/2010

 5  uric acid relief 37 years so far. i click legs knees and feet. no pain to mention genuine reply M 78 37 years
1X D
7/17/2010

 5  Gout Tired initially for first 1 month or so and then body fully adjusted to it. Also had 3-4 to be expected attacks initially as a direct result of Allopurinol cleaning uric acid deposits. Since then my 1 year long non stop Gout pain has 100% disappeared. I rate Allopurinol higher than so called God! I will take it for rest of my life with pleasure. From some of the comments here I see that some are absolutely clueless about AlloPurinol. Give Allopurionl a chance! You can't undo decades of blood uric acid build by taking AlloP for just few weeks or months! Tough it out initially and you will be rewarded. AlloP for life for me! ALLOPURINOL I bow to you literally!!!!!!!!!!!! M 36 7 months
300mg 1X D
7/18/2010

 5  I had gout in my Ankles, toes, knee As stated in previous reviews allopurinol did bring back Gout as you have to take allopurinol when you havn't got gout, but you have to stay with the plan and keep taking your daily dossage. I seem to have blurry vision and feel tired a lot at first. 1 year down the line I havn't had any gout attacks in nearly 9 months but I do take 1 x 1000mg co liver oil tablet and 1 x selenium tablet daily as a extra precaution. For both cost only £15 a years supply from ebay for both. Both cod liver and selenuim which is a trace element , both are good for the joints in the body so can only help. M 31 1 years
300mg 1X D
9/8/2010
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 5  Gout Slight tendency to diarrhoea. I was informed about this by my doctor. Beats the pain by a mile! Took several months to work fully. Have been completely pain free for sevaral years now M 66 5 years
300 1X D
9/9/2010
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 5  Gout Diarrhoea possibly caused by allupurinol M 45 8 years
300mg 1X D
11/11/2010

 5  Uric Acid control I started using it as result of gout onset. No side effects at all. Although I take the medicine daily, and it keeps my uric acid in normal levels, I still get a gout flare-up randomly, once or twice a year. M 55 10 years
10 mg 1X D
11/10/2010

 5  gout none that I can be certain are related to Allopurinol. I had several very painful attacks in the mid 1990's, then none until around 2007 or so. It is the worst pain I've ever felt, so unless a side effect were life-threatening, I would take AP. I haven't had an attack since the one around 2007. M 64 3 years
150 MG 1X D
1/7/2011

 5  Gout None After the initial 'pain' for around 2 months, have had no problems since M 51 4 years
100mg 1X D
4/8/2011
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 5  Gout None M 57 12 years
100 mg 1X D
5/15/2011
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 5  Gout None I've taken this drug for years with no flare up's that is after about the first three weeks. I tried to get off the drug once because others had told me that they had success doing so. I had a flare up about four weeks after giving it up. Now that I have been reminded how painful the flare up's can be I will never stop taking again. M 29 11 years
1X D
6/27/2011
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 5  gout No side effects. Have been gout free for nine months. Prior to allopurinol I was having gout attacks every three to four months. M 34 9 months
300 mg
12/16/2011
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 5  Gout Not aware of any been taking fo 40 years eat what I want a few beers a month and no major flare ups . Few lapses in prescription seems high stress can trigger attacks without. No attacks with daily doses M 63 10 years
300 mg
2/7/2012

 5  for gout pain no side effects for me. It doesn't work immediately, but slowly reduces attacks as uric acid diminishes in the blood. I inherited gout from my Dad's side. Started at age 30 , and I'm now 56.. If i miss my allopurinol for over a week, it can be felt in my lower joints, so I have learned by experience to not miss. It is too painful. I take 150 mg/a day. If the uric acid is allowed, thru not taking meds, to build up in the system, it will take a long time (from my experience, up to 3 months) to reduce back again to normal. I also have found out that the gout is way worse when overweight. Damn, isn't that just the way it goes with about every disease? Bottom line, don't ignore this this sleeping giant for too long. I got cocky 3 yrs ago and thought I could ignore taking the allopurinol for a few months. I ended up with excruciatingly painful swollen knees off and on for about 6 months, and my legs literally atrophied from lack of motion, because I was on crutches. Today I am completely pain free, due to allopurinol. M 56 20 years
150 1X D
1/16/2013

 5  UC (Ulcerative Colitis) None due to the Allopurinol itself. However, I take it as a XO inhibitor, to change the metabolism of Azathioprine. The Allop+AZA combo causes mild anemia (11.5-12.0 Hgb). Allopurinol increases by about 3x-4x the level of an Azathioprine metabolite that helps keep UC in remission (6TGN), and reduces manifold the levels of another AZA metabolite that is toxic to the liver (6MMPN). A combo with Allop (75mg) + AZA (50mg) has kept my severe pancolitis in remission, and brought down the level of 6MMPN from >10,000 to <250 (so it's not affecting my liver in the least). M 59 2 years
75 1X D
10/23/2012
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 5  gout none Prior to starting to take allopurinol for gout in my foot, I was looking into having my shoulder operated on because of sharp pain in my shoulder that I'd been having for a number of years. The problem with my shoulder disappeared and I could once again throw a football without fear. I have not been taking allopurinol for a couple of weeks and the shoulder problems just started to re-occur. M 56 1 years
20 MG 1X D
11/7/2012
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 5  Occasional gout in feet It seems like I have to urinate more often than before, but that could just be due to the increased fluid intake required with this medicine. I have not had a single gout flare-up since being on this medicine. M 35 12 years
6/23/2006

 5  Years of severe gout. I have not identified any side effects of Allopurinol. I take two 100mg tabs daily plus two Colchicine which combination I've been taking for about four years and have not had any gout attacks in that time. With this medication I am able to consume any food or drink desired without fear of a gout attack. Prior to beginning this treatment, I had suffered years of severe pain and periodic severe gout attacks which I countered with Ibuprofin. Kidney damage caused by the Ibuprofin dosage has reversed since stopping all NSAID usage. M 69 5 years
8/3/2006
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 5  gout and uric acid stone none i have been on it for 20 years. uric acid runs about 3.5. no side effects no gout no stones. M 81 20 years
1/1/2007

 5  Uric acid: high vlues No side effects with 100mg. Some sexual problems with 300mg, athough not very frequent. Normal values of uric acid. M 57 5 years
11/14/2006

 5  gout none to date I had gout for 6 straight and miserable weeks, after finding the right doctor and taking allopurinol every day since then I have yet to have another attack M 35 2 years
4/19/2006

 5  GOUT ZERO SIDE EFFECTSTHAT I CAN TELL IT IS A GIFT FROM THE GODS M 35 3 years
11/17/2004
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 5  High Uric Acid Level 7+ ???? If any, it could be the weather, my friends, my job or just thinking about side effects. Beats any Gout attack I ever had! For pennies a day---Haven't had a major Gout attack in years! Doc checked my Uric acid #'s a month ago. 12.6 Oh Oh! upped it to 300mg for a week(8.6), 400 for the next week (7.7), 500 the next week (6.4) Guess he found my number!! M 53 13 years
10/4/2006
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 5  Gout None. You most likely will have to take it the rest of your life M 3 years
11/7/2002

 5  Gout When I first started on Allopurinol, it triggered an acute attack of gout (my worst ever) but since then my symptoms have stadily gotten better to where I haven't had even a twinge in the last year or so. I initially resisted taking Allopurinol and tried to control my gout with diet, but after several attacks over a couple of years, I realized I was damaging my joints and the pain was causing me to not exercise. I regret not starting on it eariler. M 54 4 years
8/13/2007

 5  GOUT I HAVE HAD NO SIDE EFFECTS WHATSOEVER. I HAVE NOT HAD A GOUT ATTACK SINCE I STARTED THIS MEDICATION MY URIC ACID LEVEL WAS 8.8 [ BORDERLINE FOR GOUT ATTACKS ]. IF I ATE "WRONG FOODS- HIGH PURINES", MY URIC ACID LEVEL JUMPED, CAUSING A GOUT ATTACK. MY RHEUMATOLOGIST PRESCRIBED 150MG ALLOPURINOL DAILY, WHICH HAS MAINTAINED MY URIC ACID LEVEL AT 5.0. SINCE I BEGAN, MY FOOD RESTRICTIONS HAVE DISAPPEARED, AND I EAT WHATEVER I WISH. M 80 10 years
4/27/2007

 5  Gout No side effects I've gotten used to taking the two pills every day. It keeps the gout away...and nothing is worth bringing back that pain! M 42 2 years
8/26/2007
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 5  Gout Strong urine odor. I believe this to be my only side effect and is well worth the alternative. My first attack was around 30 and went undiagnosed for a few more years.I have had acute attacks in my toe's and both my knees at the same time. This was the worst pain I have ever had in my life. I have been on it now for aprox. 14 yrs. with no apparent side effects. M 48 14 years
1/8/2008
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 5  gout none Completely cured a years-long struggle with joint pain, swelling. Ankles, knees, big toe. I highly recommend this drug for anyone. Safe. If it doesn't help, nothing lost. M 67 12 years
11/24/2008

 5  Gout None. I have been on this medication for approximately 5 yrs. at 300mg. I had extreme pain in my large toe/joint area to the point that any slight movement would create excruciating pain. My regular physician misdiagnosed my symptoms after I told him I thought I had gout and I requested I be tested for the level of uric acid I had in my system. Given I was borderline, he would not prescribe anything and suggested I see a podiatrist, as I may have an issue with my joints. The podiatrist was a real quack in that he shot my joint up with cortisone and get the swelling down, which worked after the second time, but I suffered from this for awhile. The podiatrist even suggested I have the joint of my large toe removed and "fuse" the bones together. I would have none of this and stopped going to the podiatrist. After the last flare up, I went to my doctor and this time demanded he put me on some sort of gout medication. It was not until then, that he prescribed the allupurinol and I have never had another symptom since. Don't suffer through the M 50 5 years
11/28/2008

 5  Gouty arthritis None so far since I've only been on the drug (200mg) a short time but if it relieves or prevents attacks it is well worth it. I've suffered several gout atacks a year for about 10 years. It was bad enough when it was isolated to the big toe but now it has migrated to my ankles which at times has been literally crippling. I am an active guy (surfing, basketball, golf, etc.)but gout has turned my happy retirement into episodes of agony and inactivity which made me feel much older than my years. If allopurinol prevents attacks and enables me to get back to a normal, active lifestyle I'm willing to take it for the rest of my life if need be. It was recommended by several friends, one of whom has had a kidney transplant and is operating with just one kidney with no side effects. I'm praying that as time goes by I will find this medication to be a godsend. M 58 10 days
2/3/2009

 5  Gout Some fatigue but I take it at night to minimize impact of tiredness. I've taken Allopurinol for two years after resisting for the previous 7 years. I had a kidney stone in January 2006. Uric acid levels are particularly high in the kidneys and can greatly contribute to kidney stones. As my doctor warned, I had a particularly bad series of attacks within the first 6 weeks of starting the medication but I've had no problems since then. Kidney x-rays are clear from stones. Benefits are worth the side effects. M 43 2 years
6/11/2008

 5  Gout None whatsoever. Having had several very painful episodes of gout about 10 years ago, I was put on 300mg of Allupurinol daily. I have not had a single episode of gout since. M 44 8 years
4/27/2009

 5  Gout No side effects I've been taking alloputinol daily for fifteen years for gout and have not had any side effects or gouty episodes since starting. M 68 15 years
7/9/2009
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 5  Gout None Very effective at controlling gout. I have had no negative side effects. M 57 4 years
9/25/2009

 5  Gout / High Uric Acid 300mg/day. No major issues and no more gout! Possibly feel more tired during the day. Will follow advice of other users and try taking it at end of day instead of at breakfast. M 38 4 months
11/24/2009
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 5  Gout No side effects I am on it and know peoal who are on it, no side effects. I can now play soccer, go to gym, and no aches or pains any any joints or anywhere. Headaches first few days but are gone, M 40 2 weeks
12/19/2009

 5  Hyperuricemia (>9) No side effect. I am taking allopurinol 300 mg/day; uric acid (4-5) and creatinine (1.2-1.4) checked twice a year, remained fairly constant since the beginning of this treatment. M 65 15 years
1/4/2010
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 5  Gout attacks No side effects at all. Allopurinol is a GODSEND! I have been taking it for years and I have been Gout free since the 1st day I took it! M 47 5 days
1/16/2010

 5  Gout No side effects Great drug for controlling gout. Have tried another which I realised after a while was making me feel down but then changed to allopurinol and have had no side effects at all... or gout attacks. M 35 9 years
1/23/2010

 4  gout attacks Started taking January 2005 ( 1 x 300mg per day) No side effects until early 2009.Told July 2009 that I have suffered nerve damage to my feet and lower legs which seriously affects my mobility.Any remedy? M 71 4 years
10/2/2009
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 4  Gout My facial hair has fallen out and is slowly re-growing. After 1 year on Allopurinol I lost my beard, mustache, eyebrows and half of one eyelash. I experienced patchy hair loss on other parts of my body. The hair is starting to reappear but is slow to come back. No problems with gout since on Allopurinol. (100mg) M 53 2.5 years
10/5/2009

 4  Gout high Uric Acid I'm worried that it's what is causing frequent nausea. I also often feel tired and sore in the feet but no gout anymore. It took 9months to stop the attacks though. I'm wondering if drinking more water might help. Or if I could lower the dose now that my UA levels are very good. Plan on seeing the doctor soon the nausea is so unpleasant. But then gout would be much worse. Regarding gout triggers. I've decided unfiltered beer/ale is a trigger and only drink clear spirits distilled several times (certain brands of Vodka) No problems with those. M 54 24 months
8/9/2009

 4  Gout My side effects are not very severe. I am a little more lethargic and may be a little drowsey. Its hard to gauge. Started on 100mg and worked up to 600mg. My UA is around 4 now. Missed a day and was 8 so it works. On it about six months now and have had plenty of gout since starting. Its getting less frequent and my lumpy knuckles are gone as are the white lumps in my ear lobes so I presume I am losing MSA crystals. I'm on baking soda too. Going to reduce to 300mg and see if that keeps safe level. M 52 6 months
4/8/2009
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 4  gout drowsiness! M 55 18 days
4/15/2009

 4  Gout Extremely tired, headaches, frequent urination, dry mouth, ache all over. I would rather have the side effects than have anymore gout attacks. M 36 2 months
1/21/2009

 4  Gout No obvious side effects until I started another medication recently. Immediately suffered from dehydration, with its associated symptoms. Increased my water intake to about 3 litres per day. Great improvement. I did not know until the past week, that it is most important to consume 8-10 tumblers of water per day when on Allopurinol. In over 20 years on the tablets, cannot recall ever seeing a side effects leaflet. Only warning on the bottle, is about drowsiness/alertness. Have checked it out on the internet - allopurinol has plenty of side effects. I have been lucky. M 65 22 years
2/21/2009

 4  Hyperuricemia / Gout Increased urination upon waking up. Increased sleep(?) Good Drug. Has enabled to maintain my uric acid levels at 7 from 9 earlier. Am on 200 mg HS. M 40 2 years
9/10/2007
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 4  to check high level of uric acid I did not notice any side effects as such . However,I am experiencing low level of energy and weight gain which might be because of lack of exercise or some other reasons. I take two tablets of 100mg at a time in the morning after breakfast.It has been very effective so far. My uric acid level in the blood remained below 7 and I did not had any attack of gout since i started taking the medicine. I think diet control works to a certain extent only and it is better to keep taking Allopurinol to actually control the level of uric acid in the blood. M 42 2 years
10/19/2007
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 4  Gout Severe depression! - Strong urine smell - Some pain in kidneys. I've never been depressed before; now, I've actually contemplated suicide! (but I'd rather die than go through the severe gout again! Gout became so severe that after attacks, white uric acid crystal "paste" would erupt out of the skin from the affected joint. After that, fluid would ooze out for months. Allupurinol + Colchicine was a "must"! M 57 150 days
4/9/2007
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 4  Gout I became very depressed the day after I started taking ALLOPURINOL. However the depression only lasted a day or so. I don't believe I have experienced any other side effects from the medication. I have gout in the joints of my big toes. It was very painful. ALLOPURINOL seem to work well for me. The label instructions say take two a day. I only take one a day. I have not volinteered that info to my Doctor yet. M 49 1 years
5/3/2005

 4  Acute Gout Constipation. Numbness in feet and fingers. M 65 15 years
3/7/2004
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 4  gout None, so far.... "this" time. I had bad side effects the first time I tried taking it over ten years ago. SEVERE gout! Thank God I could take it "this" time... (Maybe it will work...) I've only been taking it (300 MG) for 3 months, but as of this writing, I have terrible gout in my left foot. (Is it working?) Had it in both hands (index) about 4 & 6 months ago! M 57 90 days
12/22/2006

 4  Gout Attacks No side effects. Attacks were 6x a year, so intense I could not walk. After the allopuinol, no attacks. I wont say I'm cured, but I will keep taking the drug. Since Target re did their pricing, only $6 YEAH! M 41 1 years
1/8/2007

 4  pre cancer treatment night sweats started a day after taking allopurinol lymphoma diagnosed, night sweats are a known symptom of this so it might be coincidental M 50 3 days
8/19/2005

 4  Gout I gained a lot of weight very quickly after starting to take Allopurinol, but my weight has stabilized since. I have read, and experienced, that gout can make people feel anguished, depressed, apprently the uric acid affects the brain, i have also heard, and i can confirm that gout can increase the risk of having a seizure (if u are epileptic) When u first start to take Allopurinol it will destroy buildups of uric acid cristals, so the amount of uric acid in the blood can actually go up before going down. So it's not at all surprizing that starting with Allopurinol causes some mental problems. I have been using it over a year now, and the only time i felt bad was when i stopped taking it for over a week. It's a really bad idea to stop, even for a few days. M 37 1 years
10/14/2005

 4  Gout Slight burning during urination. Dry mouth. Will have to take it for the rest of my life. Looks like I'm another sucker of the medical establishment. M 34 6 months
9/24/2005
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 4  Gout Not too sure yet but I think that the dull aches in some joints have occured since I started taking the tablets. I was having regular severe attacks of gout that ruined many weekends away and prevented me from any sustainable excercise plans. Since taking the 300mg tablets I have had twinges of gout but no attacks. Early days but its a god-send! How long do I take it for? M 1 months
6/21/2006
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