Drug Ratings for ALLOPURINOL

Average Rating: 3.3 (151 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)   

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RATING  REASONSIDE EFFECTS FOR ALLOPURINOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
sort down sort up F  M  
 4  Gout ( in both hands only ) Very strong urine and stool odor, shortly after starting this drug. A few abdominal pains. F 43 30 days
200 mg 1X D
5/28/2014
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 3  For high ua Rash,excessive sweating. M 27 6 months
100mg
5/4/2014
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 5  Gout initially general malaise but that was probably the gout effecting me than the zyloprim. Once the gout cleared all seemed ok. Scary side effect is erectile disfunction. Onset about 4 months ago. Taken allopurinol on and off since 29. Cycling with me getting an attack, colchicine to kill that off, then allopurinol - usually 200mg. Usually then after 7 months of no attacks I (hitherto the most recent attack that is) would drop the meds, thinking I could 'boof' it out and invariably I'd be hammered with another attack within 12-18 months - rinse and repeat. Now I aim to stay on allopurinol permanently. Worryingly I've noticed erectile performance has been severely affected in last 4 months whilst on 300mg-very embarrassing at times and no good for the psyche. Only meds I'm on so if it's meds that's it. Never ever had ed b4. I've put on weight but at 85kg and 180cm I'm not that obese. Can get an erection but not nearly as readily as before. Once a week now if lucky. Use rowing, spin machines but always have before without having been so drastically effected. It's like things are being heavily repressed rather than totally blocked. After today's celebrations (Australia Day) I'll drop the meds for a few months and see what happens. Then start and stay around 150-200mg as that was ample b4 and never had ed effects. Allopurinol also is beneficial for benign prostate enlargement so perhaps that might explain things. I don't have that but there might be some interactions happening down there. M 45 6 months
300 1X D
1/25/2014

 2  High Uric Acid Levels Teeth pain, sores on tongue, cold sweats, vertigo, shakiness and a general bad feeling. I have only been taking it for 5 days but really don't like the way I feel on it. My levels are just above normal range but after reading the horrific frequent side effects is really making me want to stop. Maybe start drinking cherry juice and eating cherries from now on. M 35 5 days
100mg 1X D
1/5/2014

 5  Chronic erosive tophaceous gout None I was walking with a cane and having such severe and constant pain.My skin was turning bright red and my controlled blood pressure was sky rocketing into stroke levels.Allopurinol has been a Godsend.I also stopped all meats,seafood,high purine veggies,sodas,beer,all liquor,except occasional white wine,stopped aspirin.I eat cherries and drink a lot of lemon water.Need to retest uric acid levels because they mite have to increase the dose. F 53 3 months
100 mg 3X D
11/20/2013

 1  Auto Immune hepatitis Fatigue, numbness, dry mouth and eyes, achiness, leg cramps and light headed and loss of appetite. I take this with 50mg of immuran. I hate this drug. F 64 3 months
100 mg 1X D
6/15/2013
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 4  severe gout in both feet intermittent stomach ache. frequent headache. Overall ok. I am 43 years old...and suffered the past 15 years with gout pain in my big toes. Going back about 6 months ago i would get pain throughout my whole foot that would basically cripple me. And for no apparent reason as far as diet went to avoid gout triggering foods. I had spent years taking Pro-gout and Colgout tablets which were fine and my attacks would subside within a couple of days. BUT i wopuld suffer terrible stomach ulcer pain and cramps due to it. 4 months ago my doctor did blood tests, and due to very high uric acid levels he put me on a 5 day course of Prednisolone which eased me into the daily taking of 1 Allopurinol tablet. The Prednisolone was fantastic and i suffered NO stomach upset...the daily taking of Allopurinol has COMPLETELY taken away my foot pain and i have already had small amounts of foods and drinks which i religiously avoided with no gout pain or effects. I can at times get an upset gut but it passes quickly. In my opinion and after suffering chronic gout for years....THIS works. Allopurinol is my saviour! I once took black cherry juice and i caused me much grief and allergy! If you suffer gout....talk to your doctor about a treatment of Predisolon easing you into a daily tablet of Allopurinol at a milligram that suits your system and you will be FREE!! :-) M 43 4 months
100mg 1X D
4/25/2013
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 1  High uric acid levels Took one pill - after a few hours, turned pink all over like a lobster, with a rash over most of my body. Went to wee in the night - fainted/collapsed for the first time in my life, and was out for 15-20min, accoring to my wife. Taken to hospital and received intravenous steroids (cortisone) which helped a bit; now at home just taking piriton - the rash is still really bad after 4 days. I have NEVER had an allergic reaction before to any food or medicine. I was first given allopurinol some months ago in conjunction with chemotherapy for leukaemia, to remove uric acid from the breakdown of cancer calls. I also had a bad rash then, which I thought was down to the chemo (it was a possible side effect). This time, not having had any chemo for 4 months, I'm sure the result was caused by the allopurinol. My wife thought I was dead. I won't be taking it again. M 64 1 days
100 1X D
1/21/2013

 5  for gout pain no side effects for me. It doesn't work immediately, but slowly reduces attacks as uric acid diminishes in the blood. I inherited gout from my Dad's side. Started at age 30 , and I'm now 56.. If i miss my allopurinol for over a week, it can be felt in my lower joints, so I have learned by experience to not miss. It is too painful. I take 150 mg/a day. If the uric acid is allowed, thru not taking meds, to build up in the system, it will take a long time (from my experience, up to 3 months) to reduce back again to normal. I also have found out that the gout is way worse when overweight. Damn, isn't that just the way it goes with about every disease? Bottom line, don't ignore this this sleeping giant for too long. I got cocky 3 yrs ago and thought I could ignore taking the allopurinol for a few months. I ended up with excruciatingly painful swollen knees off and on for about 6 months, and my legs literally atrophied from lack of motion, because I was on crutches. Today I am completely pain free, due to allopurinol. M 56 20 years
150 1X D
1/16/2013

 5  gout none Prior to starting to take allopurinol for gout in my foot, I was looking into having my shoulder operated on because of sharp pain in my shoulder that I'd been having for a number of years. The problem with my shoulder disappeared and I could once again throw a football without fear. I have not been taking allopurinol for a couple of weeks and the shoulder problems just started to re-occur. M 56 1 years
20 MG 1X D
11/7/2012
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 5  UC (Ulcerative Colitis) None due to the Allopurinol itself. However, I take it as a XO inhibitor, to change the metabolism of Azathioprine. The Allop+AZA combo causes mild anemia (11.5-12.0 Hgb). Allopurinol increases by about 3x-4x the level of an Azathioprine metabolite that helps keep UC in remission (6TGN), and reduces manifold the levels of another AZA metabolite that is toxic to the liver (6MMPN). A combo with Allop (75mg) + AZA (50mg) has kept my severe pancolitis in remission, and brought down the level of 6MMPN from >10,000 to <250 (so it's not affecting my liver in the least). M 59 2 years
75 1X D
10/23/2012
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 1  gout Dry eyes. Red around rims and lids eye doctor said I had ulcers on my eyelids. Very sensitive to light. Very vivid nightmares. My mom wakes up every time she sleeps in a panik. She says she is really seeing all this. She is full control of her mind but this is scaring her. She also has an itchy rash under her skin. I havent read all your comments yet. But if any feels they are having bad dreams they have never had before or visons in thier sleep please email me F 86 6 months
300mg
7/15/2012
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 4  Gout M 35 2 years
300 1X D
7/12/2012
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 3  gout Tired, easy brusing, dizzy, headaces, teeth ache, frequent urination, abdominal pain. Am taking 100 mg am and pm but will change to just pm. Still taking and have reduced uric acid to below 8.0. Got relief from right and left knucle but not the left big toe. Would like to stop but don't want more gout attacks. It apparently also reduces the risk for kidney stones? Also intend to try cherry juice. M 73 1 months
100mg 2X D
6/3/2012
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 1  for high uric acid level My husband took this drug for two weeks,then suffered the most horrible severe allergic reaction and was hospitalized for a month. He has to walk with a walker now due to this drug. He legs are suffering from nerve damage. He has kidney disease and this drug was building up in his diabetic kidneys. He has not walked properly since. It is really awful as it has affected his life and mine. M 66 2 weeks
300 mg
4/20/2012
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 2  Gout Itching, Welts swelled up in random locations, headaches, nausea, every joint in my body hurts now instead of just my ankle. This stuff is awful I have not had an attack in three years and the only thing I was doing was eating a bag of black cherries per every two weeks and bought enough bags to freeze for when not in season and this winter I didn't buy before the last shipment to the grocery store and low And behold 65 days no cherries and the gout is in full effect. Took allupurinol to try and make it till June but forget that I am headed to grocery store getn some cherry juice and going to choke it down it really does work and no side effects these damn doctors need to get educated on the issues they are diagnosing I was advised on cherries from my chiropractor go figure the one doctor insurance companies don't want to pay for the ones that help without the use of drugs! M 37 6 days
300
3/18/2012
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 5  Gout Not aware of any been taking fo 40 years eat what I want a few beers a month and no major flare ups . Few lapses in prescription seems high stress can trigger attacks without. No attacks with daily doses M 63 10 years
300 mg
2/7/2012

 1  High Uric Acid Gout I got really depressed. I'd start crying for no reason. I got gout 3 times and my feet and knees hurt the whole time I was on it. A month after I had been off it all my pain went away but my Uric Acid Levels are still high. M 35 90 days
300 1X D
1/31/2012
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 5  gout No side effects. Have been gout free for nine months. Prior to allopurinol I was having gout attacks every three to four months. M 34 9 months
300 mg
12/16/2011
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 3  High Uric Acid Levels fluctuating weight, rash, severe kidney stone build up (uric acid stones) I had severe attacks associated with uric acid levels when diagnosed. I was told the usual, stop the red meat, smoking, drinking and trigger food etc, problem was and is that I am a non drinker, smoker and had been a vegetarian for a couple years prior to first diagnosis and remained so for another 2 years afterwards while they mucked with diet. Instead of gout symptoms I occasionally got the weight/rash issues and when I went in for a blocked urethra this year I was informed of the discovery of 6 additional stones in my right and 4 in the left kidney and all of them well over the 11mm range, all uric acid stones. My system has not been flushing but harboring it for several years. Allopurinol has lost effectiveness and I am still now in the process of surgery for removal. Strongly suggest if you have been on this for several years to get an ultrasound on the kidneys and verify your body has not turned to working around the drug as mine has. M 38 17 years
200 mg 1X D
9/26/2011
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 1  ucerative colitis Week, painfully tired, headaches. most days I sleep once or twice during the day and get tiered a few hours latter or wake up tired. I'm taking it for ucerative colitis. It was added to 25 mg of Mercaptopurine which is a 6mp imune saprussant to make it work better to get of prednisone. No one listed here says they are taking it for UC so I wonder if I'm a Ginni pig. Has anyone took it for IBD? M 53 1 months
100mg 1X D
9/12/2011
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 1  high uric acid caused by triamteren legs became swollen,red and hot like sunburn. Some pitting on leg and peeling skin. Also nausea and chills. This was supposed to reduce the level of uric acid caused by triamterene but really messed up my legs. Slowly getting better since I am off it. Using a regimen of cherry juice that seems to be helping. F 81 21 days
100 mg 1X D
7/14/2011
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 1  Gout No gout attacks. However this drug had caused fertility issues and decreased sperm count to almost 0. Causes infertility and can also cause testicular failure. Would not recommend to any guy who possibly may want to have children. M 45 10 years
100mg 1X D
7/8/2011
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 5  Gout None I've taken this drug for years with no flare up's that is after about the first three weeks. I tried to get off the drug once because others had told me that they had success doing so. I had a flare up about four weeks after giving it up. Now that I have been reminded how painful the flare up's can be I will never stop taking again. M 29 11 years
1X D
6/27/2011
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 1  gout muscle pains - ankles, knees, shoulders, hands could not sleep or eat Too many side affects Several people have taken this drug and went into a coma. It shuts down the organs. Please be careful. M 73 3 days
100mg 1X D
6/10/2011
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 5  Gout None M 57 12 years
100 mg 1X D
5/15/2011
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 1  Crystals in the kidney Severe dry eyes and extreme sensitivity to light... optimoligist and nephroligist do not believe allopurinol is the cause but i disagree if ANYONE also experienced these side effects please email me, i would ike to know what you did to treat it F 22 1.5 years
200 1X D
4/22/2011
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 5  Gout None After the initial 'pain' for around 2 months, have had no problems since M 51 4 years
100mg 1X D
4/8/2011
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 3  gout fatigue, anxiety I don't think it is effective as cholchicine M 55 2 years
100 mg 1X D
3/27/2011
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 3  Gout I have been suffering from Gout since I was 23 now 43. I have, I think foolishly, been predudice against taking tablets every day - feeling this is a slippery slope. After a bad 2010 with many attacks I have bitten the bullet and started 7 days ago. I have constant pain in both toes but not as bad as a full blown attack, which usually effects just one toe at a time. I have read the comments and it seems a little unbelievable that the Uric Acid crystals 'melt' but I am going to persist with the Allopurinol. I have been feeling very tired. I have had a couple of very bad tummy upsets this week. I will monitor and update again in a week. Any feed back from others is gratefully received - a trouble shared is a trouble halved an all that! M 43 7 days
300 1X D
1/28/2011
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 4  Gout None so far F 68 10 days
200 mG 1X D
1/11/2011

 5  gout none that I can be certain are related to Allopurinol. I had several very painful attacks in the mid 1990's, then none until around 2007 or so. It is the worst pain I've ever felt, so unless a side effect were life-threatening, I would take AP. I haven't had an attack since the one around 2007. M 64 3 years
150 MG 1X D
1/7/2011

 3  gout Right off I noticed that I was tired all the time and at times feeling confused. About every 2 weeks I will get painful welts on my face and scalp. Slight loss of hair on head, eye lids are red around the edges. Back pain on my lower right side and both left and right sides at times. I do on occassion drink some beer but have cut down to almost nothing. Gout symtoms have almost completly gone with an occasional scare. I was putting of taking allopurinol for about five years but took the plunge after my last plolonged attack on multiple joints, ank;le, knee, wrist all on the left side. The pain was so bad I think that if there was an ax handy I would have used it on my ankle. My aim is to get my blood checked and if I like the numbers, get of this stuff, but I think it has helped thus far. Oh yeah I think the stuff does play a little with my mind. Maybe just cut my dose in half and stay on it? M 58 90 days
100 1X D
12/21/2010

 1  Gout severe allergic skin rash complete with burning, itching. "One of the most severe rashes she's seen." Immediately given prednisone and am still taking it. After 3 days, rash is starting to wane but still irritable. F 70 12 days
1X D
12/17/2010

 2  gout I have had severe fatigue, extreme forgetfulness, itchy rashes with welts on my hind legs and chest, stomach cramps, burning sensation in legs, tightness in ribcage and significant weight loss. If i don't take the medicine, I have severe gout attacks. One such attack in June 2010 kept me bedridden for 2 days and necessitated a trip to the doctor. If I take the medication, the side effects occur. Either way I've been feeling seriously under the weather due to gout since June 2010. M 53 3 months
100 1X D
11/19/2010

 1  gout dizzyness,rashes all over,sallowen lymb nods.poped red eyelid,low grade fever to high-fever to low temp in three days,nerve system damaged,vombting,above all skin,head,everywhere itching all over.even prednisone cream couldn't stopped along /w hydroxyzine. M 62 30 days
300 1X D
11/16/2010
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 5  Gout Diarrhoea possibly caused by allupurinol M 45 8 years
300mg 1X D
11/11/2010

 5  Uric Acid control I started using it as result of gout onset. No side effects at all. Although I take the medicine daily, and it keeps my uric acid in normal levels, I still get a gout flare-up randomly, once or twice a year. M 55 10 years
10 mg 1X D
11/10/2010

 2   slight hair loss, lethargic,low resistance to infections now got flu for first time in 12 years conjunctivitis twice in one month have had gout 5 times in 8 months,so not sure if its helping me at all and am very concerned about the long term effects it might be doing to my body if I continue to take it!Thinking of either alternating the dose or cutting the tablet in half!! F 62 4 months
100MG 1X D
10/10/2010
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 2  gout gout symptoms went away but had migraines one to three times a day, lowered libido, general malaise, slight depression, occasional confusion with simple questions all side effects stopped within 24 hours of not taking the medication but gout symptoms are returning so will need to find alternative medication since change in diet does nothing M 59 3 months
300mg 1X D
10/6/2010

 3  Gout Frequent urination. Urgent urination. Can't explain the different sensation felt during urination almost like pressure build up or something slowing the flow. Still pain in my foot at the joints. No wood...yes Erectile Dysfunction. M 37 30 days
100 mg 1X D
10/3/2010
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 5  Gout Slight tendency to diarrhoea. I was informed about this by my doctor. Beats the pain by a mile! Took several months to work fully. Have been completely pain free for sevaral years now M 66 5 years
300 1X D
9/9/2010
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 5  I had gout in my Ankles, toes, knee As stated in previous reviews allopurinol did bring back Gout as you have to take allopurinol when you havn't got gout, but you have to stay with the plan and keep taking your daily dossage. I seem to have blurry vision and feel tired a lot at first. 1 year down the line I havn't had any gout attacks in nearly 9 months but I do take 1 x 1000mg co liver oil tablet and 1 x selenium tablet daily as a extra precaution. For both cost only 15 a years supply from ebay for both. Both cod liver and selenuim which is a trace element , both are good for the joints in the body so can only help. M 31 1 years
300mg 1X D
9/8/2010
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 1  gout Complete fatigue, intense joint pain and suicidal 5-month, acute gout attack in both feet that encompassed the entire foot and extended half way up the calfs in both legs. Relentless red/purple swelling in the feet, no sleep for months and thoughts of suicide due to lack of sleep and unbearable pain. The doctors said that this was the worst gout they have ever seen and published photos of my left foot (the worst of the two feet). I have friends that take this drug and they are doing fine. I must be allergic to it. I have a pain tolerance that you wish you had and 5 months of Allopurinol screwed me up forever. The damage done to the connective tissue in my feet may never heal. Poison...at least for me. If you have gout make sure you go to a specialist. Most docs are morons when it comes to gout and will push you down a slippery slope. I am taking Uloric now and it seems to be the real thing....urate level at 6.3 mg/dl in 3 weeks. Make sure you have colchicine and indomethecin that you can take if a severe attack happens...I did not even know of these drugs and when the intense attack happened I was not prepared. By the time I was prescribed these drugs (3 months into the bout) they did not even touch the pain. One good thing....I am now completely immune to pain of any kind. That gout bout burned out any pain receptors. M 50 7 months
300 mg 1X D
8/22/2010

 2  gout on a weekly basis I stopped taking the drug and my gout went away. ??? go figure. M 56
300mg 1X D
7/27/2010

 4  Gout None Warning: When you start taking this drug you will have gout symptoms for 1-3 weeks b/c the medicine melts uric acid crystals in your joints. Once the crystals are gone you will have no pain and can even go off the meds, but the crystals will accumulate again and you'll have to go through the whole cycle again. Keep on it and stop eating trigger foods - you'll be cured. M 43 1 years
200 1X D
7/24/2010

 5  Gout Tired initially for first 1 month or so and then body fully adjusted to it. Also had 3-4 to be expected attacks initially as a direct result of Allopurinol cleaning uric acid deposits. Since then my 1 year long non stop Gout pain has 100% disappeared. I rate Allopurinol higher than so called God! I will take it for rest of my life with pleasure. From some of the comments here I see that some are absolutely clueless about AlloPurinol. Give Allopurionl a chance! You can't undo decades of blood uric acid build by taking AlloP for just few weeks or months! Tough it out initially and you will be rewarded. AlloP for life for me! ALLOPURINOL I bow to you literally!!!!!!!!!!!! M 36 7 months
300mg 1X D
7/18/2010

 5  uric acid relief 37 years so far. i click legs knees and feet. no pain to mention genuine reply M 78 37 years
1X D
7/17/2010

 4  Gout None Definately reduced my uric acid level but I can still get gout if I don't drink enough water M 56 18 months
300 1X D
6/24/2010

 5  early gout onset none I diagnosed my first gout attack and had it confirmed by hospital er blood test. I pressed my doctor for a uric acid remedy because I realized through some research that gout is self sustaining. The more joint damage the more attacks. He prescribed allopurinol. It works. I have had no attacks and have not suffered the joint damage that would make me over-sensitive to uric acid levels. I eat whatever I want.(within reason) My mother and a friend were poorly handled and only given anti inflammatory. I recomended allopurinol and it has helped greatly but their joint damage still allows for occasional attacks. allopurinol, don't wait! M 55 12 years
150 1X D
5/7/2010

 4  Gout Light diziness, but somewhat more energetic! Hallelajah, Praise Jesus!!! M 51 14 days
1X D
4/29/2010

 5  gout Never knew there were side effects until recent articles. Hence, I have to say I had none. I have had high uric acid levels most of my adult life. One morning some 20 years ago I woke up with a classic big toe gout attack. Following treatment for pain, I started taking allopurinol. I take one tablet each morning. I have had no symptoms since starting it. M 80 20 years
300mg 1X D
4/14/2010

 1  gout After 2 months, pain and swelling in the knees, which had never had any gout symptoms before, swelling in both great toe joints which started the great toes deviating laterally, putting pressure on the other toes. I stopped taking the allopurinol and the symptoms resolved. M 62 3 months
300 1X D
2/24/2010

 5  gout ED (yes it can cause it), cataract, tired, headaches, high billyrubin, after reading some of the comments I will share some of mine...drink more water, cut back on the alcohol, cut back on the red meat. I heard cherries or cherry juice helps. as for being tired take it at night...less chance of being tired. if need to see if taking smaller doses twice a day better then one big one. M 39
200mg 1X D
2/17/2010


History
 1  gout very dizzy and disoriented. Very out of sorts. feeling pain in joints. Dr. had me stop immiediately M 37 3 days
300 mg 1X D
2/11/2010

 2  gout dizziness, foggy head, could not focus or do my job. had to stop taking it. It's a great drug for gout if you can take it; most people can. I had to switch to uloric which is working for me. go to gout-pal.com for great advice on gout. They are not selling anything just a bunch of fellow gout sufferers with great advice. M 44 2 weeks
1/30/2010

 5  Gout No side effects Great drug for controlling gout. Have tried another which I realised after a while was making me feel down but then changed to allopurinol and have had no side effects at all... or gout attacks. M 35 9 years
1/23/2010

 5  Gout attacks No side effects at all. Allopurinol is a GODSEND! I have been taking it for years and I have been Gout free since the 1st day I took it! M 47 5 days
1/16/2010

 5  Hyperuricemia (>9) No side effect. I am taking allopurinol 300 mg/day; uric acid (4-5) and creatinine (1.2-1.4) checked twice a year, remained fairly constant since the beginning of this treatment. M 65 15 years
1/4/2010
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 2  gout i have taken allopurinol for a number of years for gout but have been off it for a while now. The side affects were kidney pain, lethergy and weight gain. I was taken off this because of surgery and not gone back. I eat lots of vegies and take black cherry juice now. No side affects. Cherry juice if good for bursitis as well as gout. You can take pills or liquid. I cured bursitis in less than a week one time. M 55 10 years
1/4/2010
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