WELLBUTRIN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (1230 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression / Anxiety Feeling Woozy, light headed, sort of a buzzed feeling and nausea. I have been on Zoloft 100 mg for three years. I have put on lots of weight and have no sex drive. Recently, my depression has started to rear it's ugly head and my doctor suggested I change to Wellbutrin. Doc put me on 100 mg 3 times daily (not extended release). The first week was very tough. I felt dizzy, woozy, sort of like I was getting drunk but not is a good way. The feeling got a lot worse during and after exercise. Lots of nausea and headaches as well. Constipation began during the second week. On the plus side I do feel more energized and alive. Less appitite and no interest in food. I really want to know when these side effects are expected to go away. Can anyone with longer experience on the drug tell me if or when the woozy feeling goes away? F 33 11 days
12/14/2008
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 4  acute depression and anxiety Possibly from Wellbutrin XL:dull headaches, spiratic agitation, slightly increased bowel movements, slight nausea, sounder sleep. Definitely from So far, so good. I never used to wake up @ 9am w/out desperately wanting to go back to sleep and I have been pretty consistently. I take .5mg of Xanax in addition for sleeplessness (PROBLEM PREVIOUS TO WELLBUTRIN XL), but I have not experienced the insomnia. Until my sex drive increased so greatly, I didn't fully realize it was such a physical an emotional issue. I have taken several others:Effexor, Lexapro, Zoloft, and Cymbalta. Though I have switched a lot-I remain hopeful. Everyone's chemical makeup is different and only (so) compatible with certain meds...Good luck to everyone...I WOULD NOT MIND ANY EMAILS..VENT..ASK ?'S..ANYTHING> F 24 11 days
3/7/2005
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 4  acute depression and anxiety Possibly from Wellbutrin XL:dull headaches, spiratic agitation, slightly increased bowel movements, slight nausea, sounder sleep. Definitely from So far, so good. I never used to wake up @ 9am w/out desperately wanting to go back to sleep and I have been pretty consistently. I take .5mg of Xanax in addition for sleeplessness (PROBLEM PREVIOUS TO WELLBUTRIN XL 300mg), but I have not experienced the insomnia. Until my sex drive increased so greatly, I didn't fully realize it was such a physical and emotional issue. I have taken several others:Effexor, Lexapro, Zoloft, and Cymbalta. Though I have switched a lot-I remain hopeful. Everyone's chemical makeup is different and only (so) compatible with certain meds...Good luck to everyone...I WOULD NOT MIND ANY EMAILS..VENT..ASK ?'S..ANYTHING> F 24 11 days
3/7/2005
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 3  major depression Iv only been taking it for 11 days. But so far my bladder is always full, no desire to eat (not a complaint, twithy cant be still, headache sometimes, one day I woke up and it felt like I had spent the day before in the gym my muscles were so sore subsided though. I see that a lot of people started itching and got a rash I really hope this doesnt happen to me. Iv been taking 300 mg of wellbutrin for almost two weeks. Its working very slowly I dont like that I have to pee every few minutes, or the twitchy like feeling. Other than that its ok. I say after a month I'll know if its good for me. I have no desire to eat had to make myself eat today was full off of half a sandwich. Gives me more energy atleast I can get through the day now. It bothers me when I'm lonely now never did until I started taking this medicine thats the only thing that makes me sad. And my mouth is dry its not really bad but I have to keep putting on lipgloss and drinking something I wake up like I'm dehydrated. F 19 11 days
2/27/2005
 3  Quit Smoking Vertigo, shakiness, anxiety, mild insomnia, appetite loss then binge. Ever changing as days into the Wellbutrin Days 1-3: Vertigo, shakiness, mild concentration loss Days 4-6: increased appetite loss which in turn has caused weight loss(for me not good), weird dreams and sleep patterns, anxiety Days 7-11: Increased anxiety, get angry, cigarettes tasting bad, have had dry mouth since the beginning, sensitive to light, short on patience, increase in energy and sex drive. Sleep patterns still somewhat messed up. My quit date is on the 14th day of taking Wellbutrin. I don't really feel like smoking, now it's more like just habit or compulsion. I worry about the anxiety as it seems to be increasing, however, with everything I'm researched on this med, chances are for me it'll gradually get better. I only got a scrip for 30 days, if it's not working by then I'll quit taking it. Wish me luck and hope I helped others. F 45 11 days
6/29/2007
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 2  depression/fatigue Severe allergic reaction resulting in rash/welts over most of my body. I took 150mg brand name Wellbutrin XL for 7 days with no noticeable side effects. Then bumped up to 300mg, which was generic buproprion XL (thanks to insurance. Day 2 of 300mg dosage had slight itchiness on backs of knees. Day 4 noticed rash developing on insides of arms and neck, unfortunately had already taken another dose. By end of day 4 rash was all over torso--back, sides, stomach, chest, insides of arms, neck and upper thighs, backs of knees and ankles. Took Benadryl and used hydrocortisone cream for itchiness. Woke up day 5 and rash had turned into giant red welts all over my body, the worst place being my lower back which looked like one huge welt. Went straight to doctor's office and had never seen such a severe allergic reaction, though she had heard of Wellbutrin skin rashes. Was given a steroid injection and put on 10 days of oral steroids (prednisone). Returned unused portion of the 300mg to my pharmacist, who had also never seen such a severe reaction. Today is Day 5 and the welts/rash is a little better, still present all over but not as red or "raised" as yesterday. Hoping this will clear up in the next few days wit F 36 11 days
4/10/2008
 2  depression, anxiety at first, dry mouth, blurred vision. headaches persistent throughout time that i was on it. Confusion and short term memory problems. I had to stop becasue i was worried about the heart pain and palpitations for the time that i was one it, it made feel like couple a couple of days. I didn't notice anything for my depression expect increased energy. the heart palplitations and stupidity, I can't have in my life. M 23 11 days
2/13/2006
 1  Horrible PMS constant headaches, nasty taste in mouth, as well as dry, burning in my stomach, hungry all the time, I probaly will gain weight with this, extreme tension in my neck and flu like symtoms Starting today, I am going off the wellbutrin, I feel worse, I was exercising daily, and in the last 11 days I have been eating non stop, trying to coat my stomach from the burning sensation, my stomach feels like it's on fire. I am glad it work for some, but not for me. F 36 11 days
8/11/2005
 5  Depression/withdrawal from Adderall Insomnia, unable to dull or escape racing thoughts, extreme depression if taking in conjunction with any Rx form of amphetamine, or even coffee. The first few days were HORRIBLE but that was mainly because I was still weaning off of Adderall. Once I wasn't taking any additional "speed", I started to notice the Wellbutrin working quite well. Honestly, Wellburtin saved my life! I was coming off of Adderall for the 5th or 6th (and FINAL) time and I wasn't sure I could pull through this one. My shotgun was loaded and ready for that one morning when the alarm clock went off and I couldn't stand the all-encompassing anguish anymore. Adderall withdrawal is the darkest, most harrowing and wrenching detox I have ever been through, tremendously worse than opiates and xanax. I had been (and still am) taking Zoloft for depression, but once Adderall is in your body it overpowers everything else and quickly drives you off the deep end. No matter how horrible your brain feels on it, you NEED it to survive. Anyhow...back to Wellbutrin. I had read about it and thought it couldn't hurt so I asked my doc about it. I literally was at the end of my rope. He thought it was a good idea so he prescribed it to me. After two days on it I didn't NEED Adderall to get through the day!! I soon found out that I couldn't drink coffee or do any caffeine either, but it is a fair trade! I've also been taking less Tramadols each day and I am almost off of them as well! I never imagined a smoother or quicker withdrawal from such a suicide-inducing drug and I am very grateful. I can actually get out of bed in the morning without M 36 12 days
150mg 2X day
3/4/2010
 4  Depression and anxiety Headaches are gone, insomnia is gone -- noticing some anxiety and irritability, such as teeth clenching, traffic bothering me more, spouse irritating me Entering 2nd week on this medication - At this point, it seems like a tradeoff. With Lexapro, I was cheerful, didn't focus on old PTSD issues, but lethargic and gaining weight. With Wellbutrin XL 300 mg, am more emotionally labile, less rested, but much more alert and engaged in life. At this point, am wondering whether I will have to choose between the two...but will keep taking for four weeks and see. F 48 12 days
3/19/2006
 3  mild depression Very little side effects--thirsty in the first few days. i am waking up 1 hour earlier than normal with no need for an alarm, but it could because I moved to a new apartment and still am adjusting to space/light. I was a little spacey for the first 1-3 days and now I pretty much don't feel anything, except I'm a little more industrious. On my doctor's recommendation, I am going to up the dosage to the 75mg 2x a day and I will repost after a few weeks of that. F 36 12 days
75mg 1X day
2/18/2013
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 3  Depression Better ability to orgasm, jittery feeling, loss of appetite, extreme mood swings, get angry easily and it's difficult to control, anxiety, and in general not feeling like myself. Also, feels like the depression has gotten worse. Hoping everything but the increased ability to orgasm will go away soon! I am on my 2nd wk of Wellbutrin XL, 150 mg/day. I took Paxil for 9 months before, and although it worked well to alleviate the depression, the side effects eventually became intolerable (extreme somnolence, weight gain, inability to orgasm). Decided to take Wellbutrin because I heard good things, and no sexual side effects. I must say that at the present moment I'm hating Wellbutrin because of the mood swings, anxiety, uncontrollable anger, etc. I feel like I have gone from being depressed to Manic-depressive!! I read that these can be normal in the beginning and should go away after taking the drug for a longer period of time, (I experienced something similar when I started Paxil that I had chalked up to the depression, but now suspect it might have been an initial response to the Paxil), so I am hanging in there for now...will let you know how it goes. F 22 12 days
5/18/2006
 3  anxiety/moderate depression felling shakey like I've had too much coffee, loss of appetite. I felt kind of "foggy" the first few days. I sleep more soundly at night. My doctor said to take 100 mg twice a day. The pharmacist told me to take one a day for three days, then if I was tolerating it well to go to two a day. I took one for six days, then tried two a day. It took 3-4 days at two a day to adjust. Now I am starting to feel better. A little more motivated and upbeat. I have stopped drinking coffee. I already feel like I've had coffee. I've been trying to make myself eat lately. I lost 5 pounds the first 8 days. Can't wait to see how I'm feeling after a couple more weeks. F 46 12 days
6/15/2007
 3  Depression Dry mouth. Very bad Insomnia. Vivid memorable dreams. Improved memory. Wired energy at night, with bouts of fatigue during the day. Is taking the edge off the depression, but too early to tell how effective it is. Will give it time, but there sure are a lot of negative reviews out there... M 64 12 days
150 MG 1X day
7/4/2020
 2  Dysthymia, Anxiety, Stress,Insomnia Generic, NOT XL or XR-Jaw & fist clenching, tremors, no sleep, visual issues similar to slight hallucinations. Overall stimulation-felt constantly agitated like a buzzing feeling, but not aggressive or angry. The 1st week I had Xanax (1mg) for sleep, but not for the 2nd week. On the 11th day I did not sleep one minute and for me this is hell. On the 12th day, I was so fearful of not sleeping due to my constant agitation, I resorted to drinking until passing out. The next day I couldn't work, was twitching, and felt like I was coming off LSD--complete with psuedo-hallucinations--light had a green tinge and patterns were slightly enhanced. The drinking is not my regular behavior, and it scared me. I stopped taking WB that day and it took 3 days to feel normal again. I had my first episode of depression in 2001 and treated it succesfully (10-20mgs prozac/day & therapy for 2yrs). I've managed w/o drugs since then (4+yrs). This year anxiety became a problem and lead to another depressive episode. I had to consider drugs again. The Dr suggested wellbutrin because I had strong sexual side affects (zero orgasm) with Prozac. He said even with my anxiety and insomnia WB might be OK. It wasn't. From reading other people's experiences, I think my dosage was too much too quickly, and I wish my Dr had recommended differently. I started with 100mg/day and ramped up 100mg every 3 days-reaching 400mg at day 10. The Dr said to ramp every 3-7 days. I was eager to feel better, and it was OK at first, so I ramped every 3 days. The hand/jaw clenching and agitation came first at 200mg, and then everything got worse. My one day on 400mg was awful, I only took 200 the next day, but there was too much in my system and it nothing improved. I then stopped because I w F 35 12 days
9/17/2008
 2  depression / anxiety Tennitus in both ears Stopped after trying 2 times to take the drug. Liked the way I felt - but the ringing in the ears is now a documented side effect but NOT when I started taking it. DRs still don't know tennitus is a side effect! Bummer. Scared now of these drugs and trying to get help to quiet my brain (ears) down! M 54 12 days
2/26/2007
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 1  Smoking cessation Extreme anxiety, panick attacks, dizziness, brain fog, derealization, blurred vision. Sides kept getting worse. Stopped after 12th day. 3 days off and sides are finally getting better. It's gradual but each day is noticeably better than the last. M 53 12 days
150mg 1X day
11/10/2023
Email
 5  depression a few nights of insomnia and some anxiety during the day Been on it for 13 days. Started at 25mg and titrated up every 4 days to 75mg in the AM and 25mg in the PM. Started noticing a stimulant effect the 1st day. Depression really started falling away on day 10 when I was at 75mg AM / 25mg PM. Feeling pretty great at day 13. Really surprised about the difference already. Was feeling hopeless that it wouldnt work even 2-3 days ago. Hang in there and it will work. It needs time to start neuron genesis growth factors in the hippocampus. Its not just a drug for increasing neurotransmitters simply. It really works by making your hippocampus gaim size again. M 42 13 days
4/10/2008
 4  depression Wild and vivid dreams were the first noticable effects.I believe this inadvertently caused a mild case of insomnia. An increase in an already healthy libido. (My poor wife who has no libido is feeling left out). Some loss of appetite also. I have never been on anti depressants before. Mine is not a severe case , just an aggravating period on my life.I have only been on 150 mg. for 13 days and I hope these side effects subside. The wild dreams are a pain in the butt and the increased libido is wild. I already had a crazy one to begin with, now I'm off the charts.Will these side effects decrease? I am suppose to double up on the dosage in a couple of days and who knows what is going to happen. I'm gonna try to enjoy the ride. By the way my depression seems to be improving. I have slowed down and I feel its easier to get through the day. I am just curious about these side effects. 55 13 days
3/5/2007
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 3  Depression/loss of focus constant headaches, my eyes feel strained and are always red, emotional rollar coaster, loss of appetite, slight increase in libido, more focus, more energy, pain in neck, I'm always shaking my legs when I sit, restlessness, irritability some days, sleeping all day sometimes or not able to sleep much at all other days. This is my eleventh day. The first week was fine, I actually liked cleaning, had more focus in school, I used to doze off in class, but never imagine doing that now. The first week I had trouble sleeping and had racing thoughts while lying in bed. Trazodone got rid of this completely. I highly reccommend it. When I started the second week, I had really frequent headaches and my eyes hurt. Two days ago (about the 9th day) I couldn't stop crying, and that weekend I slept all day and did not feel like going out or studying. Before the meds I freaked out if the apartment was dirty, and now I don't care at all. When I first started the pills I cleaned a lot, but now after 11 days I don't do anything productive. I feel like I'm on an emotional roller coaster, and I don't know what to believe anymore. Do I have insomnia or do I sleep too much? It it constatly changing everyday. Why do I not feel like doing anything some days and then wanting to do it all on other days? I guess I just have to F 20 13 days
12/3/2006
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