AYGESTIN Reviews (NORETHINDRONE ACETATE)

Average Rating: 2.9 (163 Ratings)

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AYGESTIN  (NORETHINDRONE ACETATE):  This medication is used to treat women with abnormal bleeding from the uterus. It is also used to treat women who have stopped having menstrual periods for several months (amenorrhea) but who are not pregnant or going through menopause. In addition, this medication is used to treat a condition (endometriosis) in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods. Norethindrone is a type of female hormone (progestin). It is like the hormone progesterone that your body makes naturally. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. This medication must not be used to test for pregnancy. Progestins are not effective in preventing miscarriages.   FDA Approval Date: 1982-04-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on AYGESTIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR AYGESTINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Endometriosis Weight loss All my endo symptoms improved when I started Aygestin. The biggest improvement was the amount of bloating I was having. My mood has improved, my anxiety has decreased and I'm overall in a much better place than I was before (switched from a birth control pill with estrogen). I had some hot flashes and headaches for the first few days, but those went away. My only side effect has been weight loss. F 40 2 months
2.5mg 1X day
10/14/2022
 5  Heavy periods I started on this drug for heavy periods and pain. The symptoms cleared up right away. A great side effect was uterine orgasms, in addition to vaginal orgasms. I don't really know if it's a side effect, but I had one for the first time the first night I took the drug. I love being able to schedule my period. I get my period 4 days after I stop taking it. My periods are lighter. I did get a sun spot on my face about 2 years after starting the drug. I don't know if it's related to the drug. I also have night sweats now. I think this has more to do with me getting closer to menopause. I wonder if this drug prevents me from reaching menopause. I am 59 and still get periods. My sisters reached menopause at 52-54 years old. F 59 100 days
5 1X day
7/19/2021
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 5  Endometriosis In the beginning, nothing. I started taking Aygestin in combination with the Lupron shot to help shrink the endometriosis after a lap. surgery. I've been side effect free for 14 years! I did have some weight gain, but I will take it over the pain I was having I did great for 14 years. Now I've begun to have some very light spotting and cramping. It happened for about a week in July and then again in September. It's now happening about every other week. I'm not sure if this is a side effect of the Aygestin and that my body is just too used to it now or what? I don't know if menopause is starting (I just turned 40) or if I just need to up my dose. I did call my doc. two weeks ago and he said to just make sure I'm taking it at the same time every day (which I do 98% of the time). I've never been able to find anyone who's been on it as long as I have been to see if they have any of the spotting/cramping that I have after all this time. F 40 14 years
5mg 1X day
10/6/2020
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 5  Yes its great just ran my BP up is Only high BP dr stopped me but cant stop bleeding resumes Its a much needed med F 52 2 months
10/30/2016
 5  Very long, heavy periods None Very effective. Have had no bleeding in 10 years. I'm 55 now; however, I can't figure out if I menopausal or not. Drug has messed up test results. F 55 10 years
5mg 1X day
2/7/2016
 5  Abnormal uterine bleeding My brainfog is gone, my nasal congestion cleared up and after 10 doses, my bleeding stopped. Not feeling the normal heavy daily fatigue and BONUS, losing weight. Compared to others negative reviews, this is a miracle for me. Also breast cysts have all gone down except for one. Provera started my period two weeks early(lasted 3 weeks) when in fact it was prescribed to thin the lining of my uterus to avoid excessive bleeding and clotting. FAIL! After 3 months, I was switched to Aygestin and have not felt this good for 20+ years. Thinned the uterine wall and the side effects are amazing FOR ME. I have had undiagnosed PCOS since age 18 in RT ovary only and have 3 children. 3 days 4x/day, 3 days 3x/day, 10 days 2x/day =41 pills F 48 19 days
5mg 4X day
9/30/2015
 5  hormone replacement/hysterectomy Had a hysterectomy with ovary removal in February 2015 (at 46 years and apparently not perimenopausal but feeling that I should be locked in an attic). Afterwards I dropped 25 lbs w/o effort. No menopausal symptoms to speak of. No extreme mood swings, depression, anger, anxiety, etc. Feel normal for the first time in years. Each person is different. What works for one will not work for another. My OB/GYN says I'm in the lucky 20% who don't experience extreme menopausal symptoms. Aygestin seems to regulate my hormones just fine since my hysterectomy. F 47 8 months
5mg
8/11/2015
 5  endometriosis, fibroids At first I experienced hot flashes, irritability, joint pain, swelling, and mood swing, decreased sex drive, and extreme fatigue. The symptoms started getting better the longer I took the meds. This medicine has worked wonders for me. I had two surgeries and countless other procedures but aygestin was the only thing that got rid of all my endo pain, shrunk my fibroids and helped my interstitial cystitis. This medicine takes time to work and the benefits out weigh the side effects. F 34 7 years
5mg
4/22/2015
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 5  Ovarian cysts Felt calmer, less anxious, stable mood I loved this medication. I was afraid to take it because of the listed side effects but took it anyway. I was so pleasantly surprised that I felt LESS moody than normal. I actually asked my dr if I could stay on it long term to treat the hormone imbalance causing the cysts F 49 12 days
5 1X day
10/6/2014
 5  fibroids Headache in the beginning Mood swings Has stopped my very heavy bleeding and ridiculous clots. Has anyone gotten pregnant while on this? I want to get pregnant but I don't know my cycle and if I get off if the problem will come back... F 32 4 months
5mg
5/22/2014
Email
 5  90 days Heavy bleeding Maybe a little angry. But that could be do to the fact that I read a lot of reviews for the side effects. Other than that no side effects at all! Praise GOD!!! I have had some very bad experiences with medications so I am afraid to take anything! Even too much caffeine freaks me out. I was bleeding so heavy and for so long that I had a blood transfusion. This pill saved my life! I highly recommend you try it. I always relay on ask a patient for reviews and am so grateful someone took the time to make one I promised myself I would pay it forward. Hope this helps someone who is afraid to try it like I was. F 42 9 days
5mg 4X day
1/21/2014
Email
 5  Bleeding & cramping Eating all the time. F 43 10 months
10mg
12/23/2013
 5  Heavy Bleeding This medication has been very helpful to me. Basically holding back my periods and preventing me from having a hysterectomy at this time. I just hope to use these to get myself into menopause which I don't think is very far off. I have had the worst heavy periods in the past few years and this stuff just stopped them in their tracks. Although, I did have one 2 day breakthough very heavy, but It stopped. I have had noticed my skin is more acne prone, so I have switched to acne products and for the most part it is under control. I seem to have a little joint pain, but I am not sure this is the med doing it. I have to say I am more depressed than usual. I cannot comment on weight since I have been eating out a lot the past few months, so I don't think the few extra pounds are from the aygestin. Overall it has made a huge difference for me. F 48 9 months
10 1X day
9/3/2013
 5  pcos & irregular & heavy periods No major side effects. It actually helped me keep my weight down... Decreased appetite. Stopped pain from cysts. Shut period off completely. No spotting. Wonderful drug. F 27 4 years
10mg
6/13/2013
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 5  endo Swelling of d legs. I liked this side effect because I have chicken legs =D...after my histeroscopy surgery d swelling went away.I wwonder if I could continue taking it 4 that purposes only? To have my legs thicker? =) F 46 1 months
3M
3/23/2013
Email
 5  Heavy Uncontrollable Bleeding Highly satisfied. No weight gain. A little acne but controllable. Stopped my bleeding! Diagnosed with Von Willibrands Disease and had an IUD placed and was put on a taper of this medicine. I am down to 5 mgs this week and started bleeding. Rather stay on the higher dose!! I would recommend this medicine in luie of a hystorectomy any day. F 33 3 weeks
10mg Day
2/10/2012
Email
 5   extreme weight gain, super tired at random times, brain farts, hot flashes, mood swings in the beginning, leg cramps at times i had uncontrolled bleeding to the point of needing a blood transfusion (a new Dr,) and a D&C, Two weeks later it started up all over again, Fourth trip to the ER later, I was finally given this and was told to take 4 the first day, until the bleeding subsided and stopped. It took a few days but it finally stopped and was an answer to my prayers. I went from "bleeding a river" (said by an ER Dr.) to not having to stress over it anymore. I wish there weren't side effects, but I certainly would take them over the alternative ANY day, F 48 2 years
5MG 2X day
5/18/2011
 5  adenomyosis After 4 months my blood pressure went from 100/70 to 180/110 with severe tachycardia when combining this with Advil. This med spared me from bleeding to death. I posted here to warn other users about the hypertension risk when using this at high doses, especially when combining it with Advil, Tylenol or other NSAIDs. The side effects went away a few months after discontinuing both aygestin and advil. F 53 5 months
5 mg 3X day
12/4/2010
Email
 5  uterius ceis I was so very nervous about taking this medication but, it have work great for me. I think you got to workout at the gym or do some type of walking etc. I notice the water wght gain, but, other than that it has work wonderful for me. The key is working out with this medicine will help. Drink alot of water and workout is the key. I did notice a weight gain but, thats it and it was only 5lbs no more. F 40 9 days
5mg 1X day
11/1/2010
Email
 5  HEAVY CYCLES BLOTING,INSOMINA AT TIMES,NIGHT SWEATS,HOT FLASHES,COLD INTOLERANCE AT TIMES,NAUSEA(MILD)WEIGHT GAIN(MILD) HEADACES AT TIMES! AYGESTIN HAS BEEN A LIFE SAVER FOR ME, NO MORE HEAVY CYCLES,NO MORE ANEMIC,I FEEL GREAT!NO HYSTERECTOMY AT THIS TIME!! I THINK THIS MEDICATION IS WONDERFUL! ITS BEEN SIX MONTHS NO SPOTTING OR CYCLES, SEX DRIVE INCREASE!! AGE 39! F 39 6 months
5MG 1X day
7/22/2010
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AYGESTIN  (NORETHINDRONE ACETATE):  This medication is used to treat women with abnormal bleeding from the uterus. It is also used to treat women who have stopped having menstrual periods for several months (amenorrhea) but who are not pregnant or going through menopause. In addition, this medication is used to treat a condition (endometriosis) in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods. Norethindrone is a type of female hormone (progestin). It is like the hormone progesterone that your body makes naturally. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. This medication must not be used to test for pregnancy. Progestins are not effective in preventing miscarriages.   FDA Approval Date: 1982-04-21 (Sources: U.S. Centers for Medicare Services, FDA)

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