AYGESTIN Reviews (NORETHINDRONE ACETATE)Average Rating: 2.9 (163 Ratings)Filter ResultsCompare AYGESTIN with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on AYGESTIN: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR AYGESTIN | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 4 | Endometriosis/ bad cramps | Weight gain, anxiety, shortness of breath, fatigue, headaches | I started off on 5mg and didn't feel like it was strong enough for my symptoms so we upped it to 10mg a day. It stopped my period and heavy bleeding/cramps. After taking it a while I could start to feel like I had too much progesterone( I've been on hormone meds for years and can recognize the symptoms in myself) I have cut it back down to one pill a day and feel better, resumed my period.I had some cramps but much less than before, same with bleeding. I am going to stop taking them and get a hysterectomy just because I am done with dealing with this. But the pills did what I wanted, just not a fan of the side effects. | F | 43 | 7 months 10 1X day | 9/24/2023 | 1 | Endometrial protection during perim | Felt okay at first. Then increased anxiety, mood swings, depression. Difficulty sleeping, feeling tearful. Then anxiety was horrible, couldn't regulate my moods. Very uncomfortable psychologically. The feeling of getting on a horrible carnival ride and not being able to get off. I stopped taking and felt relief + back to normal after 2-3 days. | F | 40 | 13 days 5mg 1X day | 3/13/2023 | 1 | ER visit for excessive blood | I know that I don't do well with synthetic progesterone, but I thought I would give it a chance. The first few days I actually felt surprisingly good I thought maybe it was a miracle drug, but the sixth day I woke up, unable to cope depression, fatigue, dizziness, anger. My personality was very different. | I think this drug might start out mild, and then turn on you after a week or two, according to what I’ve been reading in here. I’m looking for another solution, and I stopped taking the drug. Perhaps ablation. For me my mental health is too important to jeapordize. | F | 52 | 6 days 5mg 1X day | 1/29/2023 | 5 | Endometriosis | Weight loss | All my endo symptoms improved when I started Aygestin. The biggest improvement was the amount of bloating I was having. My mood has improved, my anxiety has decreased and I'm overall in a much better place than I was before (switched from a birth control pill with estrogen). I had some hot flashes and headaches for the first few days, but those went away. My only side effect has been weight loss. | F | 40 | 2 months 2.5mg 1X day | 10/14/2022 | 3 | Control bleeding for fibroids | Anxiety, insomnia, night sweats, nausea, appetite suppression, chills, headaches, crying, bloating, increased BP, elevated liver enzymes | I still have another 10 days on this med before I try a progestin IUD, and that feels like an eternity. Although it has stopped the bleeding except for occasional spotting, which was necessary since I had developed severe anemia, I have felt horrible on this med. | F | 47 | 23 days 5mg 2X day | 8/13/2022 | 2 | Heavy Vaginal Bleeding | It is kind of hard to tell what was due to my extremely low Hemoglobin Levels and what was due to Aygestin. I was admitted to the ER due to having a hemoglobin level of 4.8. That is when my hate- hate relationships with Aygestin started. From October-January I was on anywhere from 10-20 mg of Aygestin a day to try and stop my bleeding. Spoiler alert: it hardly helped and made me so incredibly angry alllll of the time. The mood swings were some of the worst I have ever had. | Tranexamic acid was the true winner in my opinion. Eventually I ended up having two surgeries to remove the fibroid that was ruining my life (I had a total of 14 blood transfusions between October-January). I have naturally curly hair also and taking such a high dose of Aygestin caused my hair to straighten out as well as fall out once I stopped taking it. | F | 28 | 80 days 15mg 1X day | 6/26/2022 | 1 | Menstrual pain | Insomnia, crying, emotional changes | F | 43 | 17 days 5 1X day | 6/22/2022 | 3 | Adenomyosis and fibroids | Constant mild Headache. Severe night sweats every night that began 6 days after starting the medication. Fatigue. Depression, irritability and increased anxiety. The pain and cramping from adenomyosis has significantly improved. Light menstrual cycle. Minimal spotting. | Ob-Gyn wants to continue to monitor side effects and is hoping they will subside as my body continues to adjust. | F | 43 | 3 weeks 5mg 1X day | 6/6/2022 | 1 | Endometriosis | Dizzy, nausea, extreme fatigue, muscle cramps, head ache, stomach pain, mood swings, severe depression | I only took this medicine for two weeks and had thoughts of suicide one week in. Not to mention the extreme fatigue, nausea and other unpleasant side effects. I feel better after stopping it. I will never take this drug again | F | 34 | 16 days 5 Mg 1X day | 5/30/2022 | 3 | Severe PMS symptoms | Severe mood swings, night sweats and cold flashes, weird vivid dreams. | F | 42 | 30 days 5 MG 1X day | 4/23/2022 | 4 | To stop and control heavy bleeding | Depression, chest pains, difficulty breathing, crying | After removal of Kyleena IUD, I had a heavy bleeding. Had to go to ER, got transferred into a hospital and had 3 blood transfusions. They were able to stop the bleeding with high dosage of Aygestin (10mg x 3 times a day) with Tranexamic Acid every 8 hours. I had to decide what to do next. Didn't want to do hysterectomy. Gradually started taking less of Aygestin and stopped taking TRX acid. 7.5 mg dose x 1 time a day stopped the bleeding, but gave me side effects such as chest pains and difficulty breathing. ER doctor said that these effects can be due to a Aygestin, but if I stop taking it, there is nothing else to prevent the monthly heavy bleeding. I have adenomiosis and a fibroid sized 6cm. 5mg x 1 time a day reduced the side effects, but onstead of chest pains I started feeling depressed. Went to a functional medicine doctor and he checked the levels of NY progesterone, estrogen and testosterone (I'm perimenopausal). I got 100mg of testosterone pellets in my hip that will be dissolving slowly at the rate of 1mg a day for the next 3 months and bio-identical progesterone tablets 150mg a day to help control the monthly bleeding. Now I take 2.5mg of Aygestin at 4:00pm every day and this dose doesn't give me ANY side effects and 150mg pill of bio-identical progesterone at 6:00am. This combination seems to stop the monthly bleeding completely, with a very few PMS symptoms. I plan to take both pills until my menopause is here and then I hope to stop taking it. Doctor said that a | F | 46 | 2 months 2.5 1X day | 4/20/2022 | 4 | Heavy periods, endometriosis pain | Constipation, weight gain (6 lb in the 1st month) hot flashes at night, light spotting 2-3 times per month | Started at 5 mg once per day which stopped heavy bleeding but light spotting continued every day for 2 months and endometriosis pain continued. Doctor changed dosage to 5 mg 2x per day. In that month of increasing dosage, I gained 6 pounds. I workout over an hour every day of the week and watch everything I eat. I cannot get that weight off. I have decided that I have to accept weight gain because it is the only med that has worked so far. I also have to take Benefiber to deal with constipation and now have night sweats. | F | 41 | 5 months 5 2X day | 3/11/2022 | 2 | Heavy Periods | Mood swings, anxiety, decreased sex drive, bleeding, night sweats, hot flashes and headache. | F | 40 | 43 days 5mg 1X day | 10/5/2021 | 5 | Heavy periods | I started on this drug for heavy periods and pain. The symptoms cleared up right away. A great side effect was uterine orgasms, in addition to vaginal orgasms. I don't really know if it's a side effect, but I had one for the first time the first night I took the drug. I love being able to schedule my period. I get my period 4 days after I stop taking it. My periods are lighter. I did get a sun spot on my face about 2 years after starting the drug. I don't know if it's related to the drug. I also have night sweats now. I think this has more to do with me getting closer to menopause. | I wonder if this drug prevents me from reaching menopause. I am 59 and still get periods. My sisters reached menopause at 52-54 years old. | F | 59 | 100 days 5 1X day | 7/19/2021 | 2 | Endometriosis | I started taking this 3 days after my second laparoscopic excision of endometriosis in 1/2018. At first it was amazing, no cramps, pain, or heaving bleeding. 3 months in- gastric reflux so bad (I had previously been managing my vulnerability to reflux with diet and PPI) but this was relentless, it damaged my esophagus and I ended up having a major surgery to fix (nissen). Plus- chronic nausea, dizziness, constipation, bladder spasms, severe weight gain yet decreased appetite, rage, depression/anxiety- to the point of almost taking my life multiple times, restless sleepless nights, night sweats, chills, did I mention the RAGE, not just lack of libido but full blown aversion to anything related to sex, acne on shoulders and back . Oh- and within 1 year of starting I ended up being diagnosed with Type 1 diabetes- I assume related to my genetic vulnerability and the potential of this medication to cause hyperglycemia and extreme stress on the body (triggers for those vulnerable to T1D). I have cried and cried to my doctors (GI, PCP, GYNE, endocrinologist, and endometriosis specialists) no ONE mention that all my issues could be related to this medication, because they all said- if it were related it would have started immediately upon taking, not a few months in. | I wish I had found this review site years ago. I plan to stop ASAP. I am scared, but nothing can be as bad as this has made me feel. Please reach out if you have stopped this med and let me know how long it's taken you to feel like a human being worth life again. | F | 35 | 3 years 5mg 1X day | 11/15/2020 | 1 | Endo, Focal & Diffuse adenomyosis | RAGE, irregular bleeding, night sweats, depression, fatigue, anxiety, mental anguish, irritability, insomnia, weight gain, constipation, despair. | Wish it would've worked. For the first two weeks I felt great and then a mental prison and rage. | F | 47 | 3 months 10 1X day | 10/14/2020 | 2 | To shrink endometrioma | Nausea, headache, decreased appetite, no motivation to do anything, longer periods, no sex drive, trouble sleeping. I'm constantly having cramps and feeling sick every single day. | This can't be normal. I am hoping to speak with my provider soon and discontinue this medication in the future. | F | 34 | 15 days 5mg 1X day | 10/11/2020 | 1 | Premenopause, heavy periods | Moodiness, no sex drive at all, Inability to climax, vaginal dryness- tingly arms and hands, weight gain. I live on salads and work out 4-5 days a week and can't lose the weight I gained. It did stop my periods, cramps, and breast swelling- if I wasn't married and did not care About sex, I guess it would be great. Not sure how to stop taking it. Can I stop immediately or do I need to step down? | F | 45 | 8 months 5 1X day | 10/11/2020 | 5 | Endometriosis | In the beginning, nothing. I started taking Aygestin in combination with the Lupron shot to help shrink the endometriosis after a lap. surgery. I've been side effect free for 14 years! I did have some weight gain, but I will take it over the pain I was having | I did great for 14 years. Now I've begun to have some very light spotting and cramping. It happened for about a week in July and then again in September. It's now happening about every other week. I'm not sure if this is a side effect of the Aygestin and that my body is just too used to it now or what? I don't know if menopause is starting (I just turned 40) or if I just need to up my dose. I did call my doc. two weeks ago and he said to just make sure I'm taking it at the same time every day (which I do 98% of the time). I've never been able to find anyone who's been on it as long as I have been to see if they have any of the spotting/cramping that I have after all this time. | F | 40 | 14 years 5mg 1X day | 10/6/2020 | 3 | Stop heavy period due to fibroid | While on the drug I experienced mood swings, depression, body cramps, dark spot on face. The heavy periods stopped almost immediately (only slight spotting) which was good but all the other side effects affected my daily life. I also took one Lupron shot in the first month that I started taking the medication. | Just stopped taking Aygestin about 10 days ago. Heavy bleeding, severe leg cramps, tiredness, breast tenderness started about 3 days ago. Not sure how long the effects will last. | F | 42 | 7 months 5 1X day | 10/3/2020 |
AYGESTIN (NORETHINDRONE ACETATE): This medication is used to treat women with abnormal bleeding from the uterus. It is also used to treat women who have stopped having menstrual periods for several months (amenorrhea) but who are not pregnant or going through menopause. In addition, this medication is used to treat a condition (endometriosis) in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods. Norethindrone is a type of female hormone (progestin). It is like the hormone progesterone that your body makes naturally. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. This medication must not be used to test for pregnancy. Progestins are not effective in preventing miscarriages. FDA Approval Date: 1982-04-21 (Sources: U.S. Centers for Medicare Services, FDA)