UNISOM Reviews (DOXYLAMINE SUCCINATE)

Average Rating: 2.5 (88 Ratings)

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 ANTIHISTAMINES

 Type: Over-the-counter Drug

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR UNISOMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Insomnia Accidentally took 5 once (the equate liquid gel type) and started hallucinating spiders (really sucked when I went to the bathroom), and it also made me feel like I was floating. Most recently however, it has been making me think violent and hurtful thoughts, to harm myself, or my 8 year old cat (I love my cat very much, I've raised him since he was 3 week, he imprinted into me, and I consider him to be my son) even though I know I would never harm, and if I did I'd probably end up killing myself. When I'm not taking unisom, I NEVER have any of these intrusive thoughts. If unisom does keep causing intrusive thoughts, I am going to stop taking them and get either Restoril or melatonin. M 35 8 years
200 MG 1X day
7/28/2020
 5  Insomnia I am using Doxylamine already for a few years. I live in Australia and take it in tablet form with the brand name Restavit. However, I take only 1/2 a tablet (12.5mg) about an hour before going to bed. I then take also a Valerian capsule and 1/2 teaspoon Tryptophan. The combination seems to work exept when I have been overstimulated by having visitors or working too late on my computer etc. I have Fybromyalgia and find that the anti-histamnine is something I also need for some of my allergies. So far I have not found problems with taking this but I may not recognise them because of the complaints I have with Fybromyalgia. F 56 7 years
4/14/2008
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 4  Opioid inducted insomnia So this does work for me I, but I have to take 4-5 a night in order to knock myself out and go into a sleep coma. I wake up at least once to go to the bathroom, during this time, I try not to pass back out while sleeping, and I've even fell asleep on the toilet before. So since 2018, every night after I take my unisom, I start to have really disturbing, intrusive violent thoughts, either directed towards myself, or my 8 year old cat (who I love and consider to be my son, I would never hurt him, and if I ever did, I'd probably kill myself). In order to prevent me from doing this (which I never would, but I was really disturbed and appauled that I had those thoughts and never would act on them). Before that, I had one that involved me killing myself with a katana I have. Please be mindful when you take unisom, because you may end up with the same thoughts like I had and they suck. Because of this incident, I'm going to be switching to melatonin. M 35 7 years
250 mg 1X day
8/26/2020
 4  Occasional sleep aid I experience mild personality suppression the next day, but few other side effects. I use the Unisom sleep tabs, but have learned to break them in half, and only take 1/2 tab as my dose. When I use them I take it by 9 PM and am in bed by 9:30, as I get up at 6:30 AM -- so I'm able to get a full night's rest. Taking only the 1/2 tab seems to make it much easier to control the next day side effects, yet I always get a deep sleep. I find I take 1/2 tab maybe once a month when I need to catch up on my sleep. M 62 5 years
25 mg 1X AN
3/25/2015
 3  Hard time falling asleep Extreme head to toe night sweats in the last year. I take these every night, I ran out a few days ago and suddenly no sweats the last 2 nights. The meds did help me fall asleep, I would just wake up soaking wet from sweating F 39 5 years
50mg 1X day
7/21/2021
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 1  Severe insomnia Weight gain Anger Water retention Loss of sex drive F 32 5 years
50mg 1X day
12/15/2020
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 2  Yes Hunger,weight gain In the 4 years I've taken this medication it has helped me sleep but I've become overweight since starting it mainly because it makes me mindlessly eat hundreds of calories more than my unusual intake. The hunger feeling is so great I eat just to shut it up. I went from 150 pounds to 175 pounds and in my entire 29 years of life I've never put on weight so fast or struggled so hard to get it off. I only recently decided to track when my weight gain first started the time is nearly to the week that I started the unisom that the first two or three pounds appeared. I believe I have to stop it completely to loose weight. Hopefully my sleepless nights don't come back to hunt me F 29 4 years
100mg
7/31/2016
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 4  Insomnia Having used sleeping meds for years and after having become highly addicted to them, Unisom brought me wonderful relief from extended insomnia when I had to stop the sleeping pills. Be warned though! I now have HYPER acidosis! Have to take up to 80mg's of acid blocking P.P.I's due to a totally messed up gastric system now. This has lead to ulcers and now gout type arthritis which the Physician says all stems from having used Unisom for close on 3 years. F 51 3 years
1/21/2008
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 5  Insomnia; to sleep Sometimes groggy in the morning. I usually take it when I know I don't have to get up early, and I let it put me back to sleep for a while. My seventeen year old daughter and I both have insomnia. For her, Unisom Sleepgels have worked very well. I have had to take something stronger most nights, and am currently taking Ambien. But on occasional nights, I do take the same Unisom Sleepgels that my daughter does. They work very well. Sometimes it takes a while for them to take effect, so I will take one an hour or so before bedtime. They often keep me very sleepy the next morning, so when I take them, I try not to plan too many morning activities. At the time they do put me to sleep, they feel very strong for an over the counter medication. F 49 2 years
1 Sleepgel 1X day
10/1/2010
 3  insomnia It puts me into a very deep sleep. Bad tremor and shakes. Nothing else makes me sleep so deep. Some depression. I have taken many psychiatric drugs and Unisom works better for sleep. Overall good experience. M 43 2 years
25mg
11/20/2014
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 1  Insomnia depression, anxiety, sleeplessness, dry mouth, hangover. Effects have been bad for me. Its my belief that after taking this drug for months that it has made my depression and anxiety much worse. I would not recommend using Unisom or other antihistamines over any period of time if you are predisposed to depression or anxiety. Like other hypnotics, sleeping pills alter brain chemistry the same way. Benzos, antihistamines, and SSRI's (antidepressants) target GABA receptors in the brain. Taking Unisom or other hypnotics will only mask the causes of insomnia, you will fall asleep, but it will be unnatural. This is what gives you that "hangover" effect when you wake up in the morning. That "hangover" effect may have cumulative negative effects on your brains normal operation and can, over time, make depression and anxiety worse. We know depression, anxiety, insomnia are all related. I know its tempting for doctors and patients to seek a quick resolution of insomnia or depression since they impact your life greatly. But I would caution against using Unisom or other sleep agents if you have depression/anxiety and seek practical, natural, and behavioral steps to alleviate your insomnia. There is very little information about doxylamine succinate. These drugs have only been around for a few years while insomnia, depression, and anxiety have been around for as long as human kind. We cannot fool ourselves into taking new drugs for ages old conditions. Unisom, Benzos, SSRIs, & antihistamines side effects are t M 26 2 years
25mg 1X day
2/17/2011
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 5  insomnia morning grogginess, difficulty waking, increased appetite in morning I became reliant on these tablets for sleeping so cut my dose to a quarter of a tablet and increased to half if still unable to sleep. Now I only use for emergencies. Very helpful! F 25 1 years
12.5 1X day
10/26/2010
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 4  Insomnia A very effective insomnia remedy. Better than sleeping tablets. The down side is that over time you need to keep on upping your dose till you reach a point where you are actually overdosing as you become tolerant very quickly to the Unisom (Doccylacime Succinate.) For people with gastric sensitivity it is worth keeping in mind that this is actually an anti-histamine and can mess quite badly with the acid contents of the stomach. F 50 1 years
7/15/2007
 4  Insomnia First time I took it I experienced anhedonia, emotional blunting and fatigue. But I took whole 25 mg tablet. I realized I can induce sleep with as little as 7mg, which is roughly a third of the tablet. Any sedation is counteracted with caffeine next day. Nowadays I have to take the whole tablet though, I still get decent sleep though. But I always reacted poorly to benzos and other GABAenergic drugs. F 27 1 years
12.5-25mg
12/25/2013
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 3  Insomnia Next day feeling low, depressed like. If I wake up in the middle of the night and take some I might really feel depressed the next day. Besides being an antihistamine I believe it blocks acetylcholine. I've used Unisom off/on for about 1 year or so. This is the one of the only things that helps me fall asleep and stay asleep. But some times it gives me next day depression which is not fun. M 48 1 years
25mg 1X day
1/30/2018
 3  Insomnia Agitation, irritability, depression This drug worked well at getting me to go down, but I woke up several times during the night and the next day I would feel worthless, agitated, and depressed. All sleeping medicines cause this for me for some reason. I'm trying to go to sleep naturally now. This is just my experience, it may work fine for you. F 30 1 years
25 MG 1X day
8/9/2013
 1  Insomnia I have had a long journey with insomnia. I got on unisom after deciding Tylenol PM was probably bad for my liver daily. It's been about a year of unisom & I have been putting on weight like crazy. I've gained about 13lbs. I constantly eat, and don't feel full. I'll fall asleep & wake up with intense cravings for food. Normally sweets. I finally realized that unisom is an antihistamine like another med I was on (hydroxozine) that made me blow up, so I've pulled the cord on them. Apparently even melatonin which I used with unisom nightly slows your digestion. I've quit both cold turkey & last night (first night off) was brutal. I've gotten barely any sleep & I'm sweating like crazy. Hopefully this blows over sooner than later 🤞🏼 F 35 1 years
50mg 1X day
8/19/2023
 4  Insomnia Lingering grogginess in the morning. Even though this is an over-the-counter drug, as far as inducing the feeling of sleepiness, it is one of the most powerful I've tried and, in that respect, works better than both Ambien and Lunesta. The problem with it for me is that it can take over an hour to kick in -- but when it does you'd better be in bed or close by. It's so strong that I have to buy it in the oval tablet form and break them in half. If I took a whole one, I'd still be in a fog for over half of the next day. As it is, even with the half tablet, I'm still too groggy in the morning which is why I don't use it more. But it's a very effective sleep medicine. M 51 18 months
10/9/2006
 3  insomnia tolerance, numb hands arms F 46 6 months
9/23/2009
 1  Insomnia I didn't realize until reading all of these reviews that this medication is responsible for my heart palpitations, anxiety and tight chest! I dreaded bedtime and had sleep anxiety but after 2 weeks without taking it everything went away!!! It was also making me gain weight which I could not figure out! Hate this crappy med! Don't take it!!! This medication also was also responsible for my tight chest and squeezing sensation which hurt and felt like i was having a heart attack all the time! F 55 6 months
25 mg 1X day
5/31/2021
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